방사선 센서의 동작특성

임영화,한상효,김도성,강희동 경북대학교 센서기술연구소 1995 센서技術學術大會論文集 Vol.6 No.1

A Geiger-M□ller(GM) radiation sensor is fabricated by using the vacuum system and gas feeding system. The base pressure of the vacuum system is 1X10^(-7)torr, and two MFCs(0~10sccm, ±1% accuracy of the full scale) are used to control the composition of filling gas exactly. The fabricated GM radiation sensor is simultaneously filled with the mixture of neon and clorine. The mica window(7.43mg/cm^(2)) is attached to the GM radiation sensor. The optimized GM radiation sensor has about 660V starting voltage, 125V plateua length, and 10%/100V plateau slope.

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

레슬링선수들의 체중감량에 따른 섭취열량과 신체조성의 변화

백영호,염종우,염원상,김세종,서혜림 부산대학교 체육과학연구소 2000 體育科學硏究所 論文集 Vol.16 No.-

This study was to find out calorie intake and body composition changes in accordance with weight loss of wrestlers. The wrestlers were divided three groups : no weight loss groups, 5∼7% weight loss group and over 7% weight loss group. And they were observed three : before weight loss, at measuring weight and before games. The following are the conclusion of this study: 1.The changes of calorie intake 1) Before weight loss, the percentage of the daily intake to the daily energy expenditure was 57.7% for the no weight loss group, 47.2% for the 5%∼7% weight loss group and 53.7% for the over 7% weight loss group. 2) The calorie intake of each group per meal: the no weight loss group intake 1,118kcal before weight loss, 760.9kcal before weight measurement and 1026.8kcal from after weight measurement to before games, and the 5∼7% weight loss group intake 955.4kcal before weight loss, 483.1kcal before weigh measurement and 880.4kcal from after weight measurement to before games, and the over 7% weight intake 959.3kcal before weight loss, 339.4kcal before weight measurement and 872.7kcal from after weight measurement to before games. 3) The ratios of calorie intake(protein : fat : glucose) : the no weight loss group showed 16.7∼35.1% : 20.8∼23.8% : 44.1∼60%, the 5∼7% weight loss group showed 15.5∼26.6% : 22.2∼23.7% : 50.6∼62.3% and the over 7% weight loss group showed 15.0∼30.2% : 19.6∼27,6% : 50.7∼59 4%. 2.The changes in body composition 1) After weight loss, weight and BMI changes in accordance with weight loss among groups showed meaningful differences in all circumstances : weight, before games versus at measuring weight and before weight loss versus before games.(p≤.001) 2) In the changes of total body water, protein, mineral, fat mass and %fat in accordance with weight loss among groups, when we compared those of before games with those of at measuring weight, we found that the over 7% weight loss group showed a meaningful increase over the no weight loss group.(p≤0.5) 3) In the changes within groups, though we found no meaningful difference, total body water, protein and mineral of before games were less than those of before weight loss, and fat mass and %fat of before games were higher than those of before weight loss. According to the results of this study, the wrestlers lost their weights intensively in three days before games by eating less and when lean body mass was restored, the level was lower than before weight loss. Therefore, these results intake the weakness of exercise capacity, long-term weight loss plan is more helpful than short-term weight loss, and for the enhancement of exercise capacity systematic plan and training of the weigh loss should be done.

환경호르몬에 관한 연구동향과 안전대처 방안

염원상,이의철,서혜림,김세종,백영호 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-

From a theoretical research on recent investigations of endocrine disruptors, the results of this study were as follow; 1. Endocrine Disruptors means an exogenous chemical substance that causes adverse health effects in an intact organism, or its progeny, consequent to changes in endocrine function. 2. It is required that the cooperative study and research is propelled among administrative organs, scientific research companies and the common people companies for fundamental protecting about endocrine disruptors. 3. It is necessary that the network data-base and international cooperation works should be intensified. 4. Development of techniques which can distinguish and classify the endocrine disruptors, more testing and continuous monitoring are required.

원발성 조기 위 소세포암

송근영,강길,박정희,김경종,민영돈,박치영,임성철 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

Gastric small cell carcinoma(SCC) is defined as poorly-differentiated neuroendocrine tumor of the stomach, and their morphologic and biologic features arc similar to those of the lung. It is known that this tumor has poor prognosis even in early pathologic stage, It acounts for only 3% of all gastrointestinal SCC. that has been reported only 33 cases outside and 6 cases inside of the comitiy. Most of these reports are related to advanced gastric SCC. as pathologic stage IIIb or IV. This report describes a case of early gastric SCC. pathologic stage Ib.

요통환자에 있어서 MRI 소견상 추간판 팽윤의 임상적 의의

선호영,조성일,이정웅,임상덕,정상돈,윤영석 최신의학사 1993 最新醫學 Vol.36 No.12

SD Rats를 이용 1-hexene의 흡입독성 연구

김현영,임철홍,정용현,이권섭,이성배,이준연,한정희,전윤석,이용묵 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

The purpose of this study was to investigate the acute (4 hours) and repeated-dose (6 hours a day, 5 days a week, 4 weeks) toxic effects of I -hexene on Sprague- Dawley (SD) rats which were treated by inhalation. The results were as follows; I. The median lethal concentration (LC_(50)) was estimated 52,694 ppm (confidence limit 95%; 49,494~55,447 ppm) in acute inhalation. Abnormal clinical signs related to the l-Hexene were not observed with the acute inhalation dose. Gross findings of necropsy revealed on evidence of specific toxicity related to the 1-hexene, II. By repeated inhalation exposure the body weight of male were more or less reduced by the dose of 2,500 ppm and 5,000 ppm compared with control group. However there were no significant variation hematology and blood biochemistry for the exposed rats compared with the control rats. Abnormal clinical signs and gross findings of necropsy related to the 1-hexene were not shown. In conclusion when we exposed I-hexene to SD rats for 4 weeks, 5 days per week, 6 hours per day, the Lowest observed effect level (LOEL) was over 2,500 ppm and Non observed effect level (NOEL) was below 500 ppm.

인슐린 비의존성 당뇨병에 동반된 심상성 천포창 1 례

이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.

크롬(Ⅵ)의 체내 흡수와 소실속도에 관한 연구

김현영,이성배,임철홍,이권섭,정용현,이종성,한정희,전윤석,황호순,이용묵 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.1

The CrO3 mostly used in plating. metal surface disposal, leather, cosmetic manufacturing, as an experiment material by repeatedly inhaling and exposure the male S.D. rats at a 0.00, 0.2., 0.50, 1.25 mg/㎡ concentration(particle size: 0.5-0.5 aerosol)6hours a day, 5day a week in 13weeks comparing with 2weeks, 8weeks of recovery group about the noxiousness of the experiment animal and the reduce scale of the CrO3 in the internal organ especially in blook and respiratory organ with the period of convalescent and clearance. The experiment results which we received are as follows. 1. In blood the RBC, HGB and HCT experiment, rats with 0.20, 0.50 mg/㎡ concentration showed that there were some decreases but not dependent. The kidneys absolute weight compared with control group was reduced intentionally(p〈0.05) and the lungs absolute weight compared with control group showed intentional increase(p〉0.05). 2. After the exposure of the experiment material, the whole blook, l\blood plasma and red blood cell in blood by (x): the period of convalescent, per (y); the decreasing of Cr concentration, was y=66.51 e -0.057x, y=67.2 e-0.101x, y=70.01 e-0.030 in 0.50 mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life (day)was estimated 12.0, 6086, 23.0 each. 3, After the exposure of the experiment material, the experiment animals lung, liver and kidneys by(x); the period of convalescent, per (y); the decreasing of Cr conentration, was y=1808 e-0.00493x, y=12.02e-0.0297x, y=67.61 e-0.0292x in 0.50mg/㎡ exposure concentration by calculating the clearance coefficient of correlation, and the half life(day)was estimated 140.6, 23.3, 23.7, each, and including lung, liver with all of the experiment internal organs, the Cr clearance decreased as the exposure concentration increased.

S.D. Rats를 이용 1, 1-Dichloro-1-fluoroethane의 아민성 흡입독성 연구

김현영,이성배,임철홍,김철우,점용현,한정희,전윤석,최수영,강대봉,이용묵 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

There were no specific effects for test materials on Sprague-Dawley (S.D.) rats in clinical symptoms, amounts of food intakes, weight changes, laboratory findings, and pathology after whole body l, l-Dichloro-1 -fluoroethane (used as coolant, metal cleaner and solvents) exposure(0, 1,500, 3,000, and 6,000 ppm) for 13 weeks (6 hour/day, 5 days/week). However, the loss of capillary vessels in eyeball (pupil) was observed in a female rat among 6,000 ppm group. Though there was a tendency for MCHC (Mean Corpuscular Hemoglobin Concentration) in rat to be decreased (p<0.05), it was not regarded as abnormal because the values were within normal limits. In asthma-stimulation related evaluations, there was also a tendency for inflammatory cell counts in bronchoalveolar lavages to be increased. But it had no statistical significance, and also no dependency on sex and the exposed concentration. Based on this result, the non observed effect level (NOEL) induced by 1, 1-Dichloro-l -fluoroethene inhalation was evaluated in groups with 3,000 ppm below (S .D. Rats, 13 weeks). Finally, it was concluded that the short term exposal of 1, 1-Dichloro-l-fluoroethane is not considered as a asthma stimulant by inhalation despite of some study limitations such as test animals use and short-term exposure .