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Wen-Jie Si,Xun-De Dong,Fei-Fei Yang 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.5
This paper investigates adaptive tracking control for a more general class of stochastic nonlinear timedelaysystems with unknown input dead-zone. For the considered system, the drift and diffusion terms containtime-delay state variables. In control design, Lyapunov-Krasovskii functionals are employed to handle unknowntime-delay terms. Then, unknown nonlinear functions are approximated by RBF neural networks, and the dynamicsurface control (DSC) technique is utilized to avoid the problem of explosion of complexity. At last, based onthe Lyapunov stability theory, a robust adaptive controller is designed to guarantee that all closed-loop signals arebounded in probability and the tracking error converges to a small neighborhood of the origin. The simulationexample is presented to further show the effectiveness of the proposed approach.
Zhao Xun,Cui De-Jun,Yang Liu-chan,Yuan Wen-Qiang,Yan Fang 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.5
BACKGROUND: This study commenced to uncover the role of long non-coding RNA FBXL19 antisense RNA 1 (FBXL19-AS1) in the development of ulcerative colitis (UC) and its possible mechanism. METHODS: FBXL19-AS1 expression in the colonic sigmoid mucosa of UC patients was detected. A colitis model was induced in mice using 5% dextran sodium sulfate. Hematoxylin–eosin staining was performed for histopathological examination. Apoptosis was detected by Tunel staining and tissue fibrosis was detected by immunohistochemistry. Also, intestinal permeability was examined. The concentrations of inflammatory factors IL-1b and IL-18 were detected by enzyme-linked immunosorbent assay. The relationship between FBXL19-AS1, miR-339-3p and RHOB was verified by RNA immunoprecipitation assay and dual luciferase reporter assay. RESULTS: The expression of FBXL19-AS1 was increased in dextran sodium sulfate (DSS)-induced colitis mouse model. FBXL19-AS1 interference or miR-339-3p overexpression inhibited DSS-induced colonic epithelial cell apoptosis and inflammatory response, and improved intestinal epithelial barrier defects, thereby ameliorating DSS-induced colitis injury in mice. FBXL19-AS1 sponged miR-339-3p while miR-339-3p targeted RHOB. Overexpression of RHOB reversed the protective effect of inhibition of FBXL19-AS1 on DSS-induced colitis in mice. CONCLUSION: FBXL19-AS1 reduces miR-339-3p-mediated targeting of RHOB and aggravates intestinal epithelial barrier defect in DSS-induced colitis in mice.
MySQL 기반의 역파일 검색엔진 시스템 효율성에 관한 연구
김문걸(Wen-Jie Jin),김광훈(Guang-Xun Jin),최운수(Woon-soo Choi) 한국엔터테인먼트산업학회 2010 한국엔터테인먼트산업학회 학술대회 논문집 Vol.6 No.1
현재 최고 인기 있는 정보 검색 기술로 전문 검색을 꼽을 수 있다. 하지만 이 검색 방법은 정보의 양이 많아짐에 따라 검색의 효율도 점점 낮아진다. 본 논문에서는 전통적인 역 검색(inverted index) 방법의 결점을 분석하고 상기 문제점을 해결하고자 한다. 텍스트를 여러 개의 논리적 블록으로 나누어 Elias-gamma 코드 압축 기법과 hill-climbing 알고리즘. 그리고 역 검색의 알고리즘을 이용하여 검색 시스템의 효율을 개선한다. Currently, the most popular information retrieval technology is full-text retrieval. however, with the information more and more, the efficiency of this method also lower and lower. This paper analyze the defects of traditional inverted index, present the logic sub-block of text and compress with Elias-gamma coding, then present to use the hill-climbing algorithm as the search algorithm of inverted index, improved the system efficiency.
Guang-Xun Lin,Li-Ru He,Jin-Niang Nan,Wen-Bin Xu,Keyi Xiao,Zhiqiang Que,Shang-Wun Jhang,Chien-Min Chen,Ming-Tao Zhu,Gang Rui 대한척추신경외과학회 2024 Neurospine Vol.21 No.1
Objective: This meta-analysis aims to refine the understanding of the optimal choice between different cage shapes in transforaminal lumbar interbody fusion (TLIF) by systematically comparing perioperative data, radiological outcomes, clinical results, and complications associated with banana-shaped and straight bullet cages. Methods: A meticulous literature search encompassing PubMed, Embase, Scopus, Web of Science, China Knowledge Network, and Wanfang Data was executed up to October 5, 2023. Inclusion criteria focused on studies comparing banana-shaped and straight bullet cages in TLIF. The quality of included studies was assessed using appropriate tools such as the Newcastle-Ottawa Scale (NOS) for nonrandomized studies. Rigorous evaluations were performed for radiographic outcomes, including disc height (DH), segmental lordosis (SL), lumbar lordosis (LL), subsidence, and fusion rates. Clinical outcomes were meticulously evaluated using visual analogue scale (VAS), Oswestry Disability Index (ODI), and complications. Results: The analysis incorporated 7 studies, involving 573 patients (297 with banana-shaped cages, 276 with straight cages), all with NOS ratings exceeding 5 stars. No statistically significant differences were observed in operative time, blood loss, or hospitalization between the 2 cage shapes. Banana-shaped cages exhibited greater changes in DH (p = 0.001), SL (p = 0.02), and LL (p = 0.01). Despite statistically higher changes in ODI for straight cages (26.33, p < 0.0001), the actual value remained similar to banana-shaped cages (26.15). Both cage types demonstrated similar efficacy in VAS, complication rates, subsidence, and fusion rates. Conclusion: Although banana-shaped cages can excel in restoring DH, SL, and LL, straight bullet cages can provide comparable functional improvements, pain relief, and complication rates.
Rong Jia,Wen Xun,Guozhou Liao,Yuan Yang,Guiying Wang 한국축산식품학회 2023 한국축산식품학회지 Vol.43 No.6
The fatty acid composition and small molecular metabolites in breast and leg meat of Yanjin blackbone chickens (YBC) and Piao chickens (PC) were detected by gas chromatography-mass spectrometry and liquid chromatography-quadrupole static field orbital trap mass spectrometry. Thirty-two fatty acids were detected, and the total fatty acid content of PC was significantly higher than that of YBC (p<0.05). Oleic acid, linoleic acid, palmitic acid, stearic acid, and arachidonic acid were the main fatty acids in the two chicken varieties, and the composition of fatty acids in the two varieties were mainly unsaturated fatty acids, being more than 61.10% of the total fatty acids. Meanwhile, 12 and 16 compounds were screened out from chicken legs and chicken breasts of YBC and PC, respectively, which had important contributions to the differences between groups.
Jin, Zhe,Wang, Wen-Fei,Huang, Jian-Ping,Wang, He-Meng,Ju, Han-Xun,Chang, Ying Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Background: Biological and pharmacological activities of dryocrassin ABBA, a phloroglucinol derivative extracted from Dryopteris crassirhizoma, have attracted attention. In this study, the apoptotic effect of dryocrassin ABBA on human hepatocellular carcinoma HepG2 cells was investigated. Materials and Methods: We tested the effects of dryocrassin ABBA on HepG2 in vitro by MTT, flow cytometry, real-time PCR, and Western blotting. KM male mice were used to detect the effect of dryocrassin ABBA on H22 cells in vivo. Results: Dryocrassin ABBA inhibited the growth of HepG2 cells in a concentration-dependent manner. After treatment with 25, 50, and $75{\mu}g/mL$ dryocrassin ABBA, the cell viability was 68%, 60% and 49%, respectively. Dryocrassin ABBA was able to induce apoptosis, measured by propidium iodide (PI)/annexin V-FITC double staining. The results of real-time PCR and Western ting showed that dryocrassin ABBA up-regulated p53 and Bax expression and inhibited Bcl-2 expression which led to an activation of caspase-3 and caspase-7 in the cytosol, and then induction of cell apoptosis. In vivo experiments also showed that dryocrassin ABBA treatment significantly suppressed tumor growth, without major side effects. Conclusions: Overall, these findings provide evidence that dryocrassin ABBA may induce apoptosis in human hepatocellular carcinoma cells through a caspase-mediated mitochondrial pathway.
Leilei Xu,Xueying Wen,Mindong Chen,Chufei Lv,Yan Cui,Xianyun Wu,Cai-e Wu,Zhichao Miao,Xun Hu 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.100 No.-
The mesoporous nanosponge MFI silicate zeolite was facilely fabricated by employing the long chainammonium as the structure-directing agent. The zeolite with both mesoporous and microporouschannels were selected as the support of Ni-La catalysts for methanation of CO2. Various techniques wereused to characterize the catalysts systematically. The effects of the La2O3 promotor and pore morphologyof the support on the catalytic performance were carefully investigated. Our study demonstrated that Lapromoter could be beneficial to the increase of the surface basicity and the enhancement of the metallicNi dispersion. This would intensify the processes of the CO2 chemisorption and H2 dissociation in CO2methanation. Besides, we also found that the catalyst supported on mesoporous nanosponge MFI zeoliteperformed higher activity and better long-term stability than the reference catalysts supported on bulkMFI and MCM-48, suggesting that the synergistic effect between the mesoporous and microporouschannels displayed unique advantages. Kinetic study revealed that both the nanosponge structure andLa2O3 promoter contributed to decreasing the reaction activation energy. Therefore, the present highlydispersed Ni-La catalyst over mesoporous nanosponge MFI zeolite promised a potential catalystcandidate for low-temperature CO2 methanation reaction.