An Adaptive Discrete-Time ILC Strategy using Fuzzy Systems for Iteration-Varying Reference Trajectory Tracking

Teng-Fei Xiao,Xiao-Dong Li,John K. L. Ho 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.1

In this article, a novel fuzzy systems based on adaptive Iterative Learning Control (ILC) strategy is presented to deal with a class of non-parametric nonlinear discrete-time systems which perform iteration-varying reference trajectory tracking. Using the technique of fuzzy systems to compensate for the non-parametric uncertainty of the discrete-time system dynamics, the proposed adaptive ILC scheme can well track the iteration-varying reference trajectory beyond the initial time points. The convergence of the fuzzy systems based adaptive ILC algorithm is guaranteed by theoretical analysis, and a numerical example is given to illustrate the effectiveness of the adaptive ILC scheme.

Finite-element-method based Adaptive Iterative Learning Control for a Rapid Thermal Processing System

Teng-Fei Xiao,Xiao-Dong Li,Qing-Yuan Xu 대한전자공학회 2020 Journal of semiconductor technology and science Vol.20 No.1

For the temperature regulation in a rapid thermal processing system in semiconductor manufacturing, we develop an adaptive iterative learning controller based on the finite-element-method in this paper. A finite-dimensional model of the system is constructed by the finite-element-method firstly. Then, adaptive iterative learning controller is designed based on the finite-dimensional model. Simulations are performed by heating the wafer in the system with the developed control method. Simulation results show the effectiveness of the proposed adaptive iterative learning controller.

Pretreatment with the Total Flavone Glycosides of Flos Abelmoschus manihot and Hyperoside Prevents Glomerular Podocyte Apoptosis in Streptozotocin-Induced Diabetic Nephropathy

Lei Zhou,Xiao-Fei An,Shi-Chao Teng,Jing-Shun Liu,Wen-Bin Shang,Ai-Hua Zhang,Yang-Gang Yuan,Jiang-Yi Yu 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.5

Diabetic nephropathy (DN) is an important diabetic complication, and podocyte apoptosis plays a critical role in the development of DN. In the present study, we examined the preventive effect of the total flavone glycosides of Flos Abelmoschus manihot (TFA) on urinary microalbumin and glomerular podocyte apoptosis in experimental DN rats. The preliminary oral administration of TFA (200 mg/kg/day) for 24 weeks significantly decreased the urinary microalbumin to creatinine ratio and 24-h urinary total protein in streptozotocin-induced DN rats. Terminal deoxynucleotidyl transferasemediated dUTP nick end-labeling assay indicated glomerular cell apoptosis in DN rats was significantly improved by pretreatment with TFA. Furthermore, fluorescence-activated cell sorting and Hoechst 33342 staining suggested preincubation with hyperoside (50 and 200 lg/mL), the major active constituent of TFA, could significantly mitigate cultured podocyte apoptosis induced by the advanced glycation end-products (AGEs). Western blot analysis showed that increased caspase-3 and caspase-8 expressions induced by AGEs were also inhibited by pretreatment with hyperoside at both doses. Our results demonstrate that TFA pretreatment can decrease urinary albumin excretion in early-stage DN, which might be accomplished by preventing renal damage and podocyte apoptosis.

Tissue-specificity of RNA editing in plant: analysis of transcripts from three tobacco (Nicotiana tabacum) varieties

Fang Jing,Jiang Xiao-Han,Wang Teng-Fei,Zhang Xiu-Jun,Zhang Ai-Di 한국식물생명공학회 2021 Plant biotechnology reports Vol.15 No.4

RNA editing is a significant post-transcriptional molecular process of modifying the primary transcripts by editosome. In plants, it remains unknown whether and to what extent RNA editing contributes to tissue-specific regulation from a global perspective. To obtain an overview of RNA editing events in model plant tobacco (Nicotiana tabacum), we implemented a bioinformatics analysis of DNA-Seq and RNA-Seq data from roots and leaves of three tobacco varieties (TN90, Basma and K326). The results showed that hundreds of RNA editing sites were detected to be located in the protein-coding region of plastid/mitochondria for all three varieties. Among these sites, some of them were detected in leaves but not or reduced in roots. Interestingly, most of the disappeared editing sites in roots were located in plastid transcripts encoding subunits of NADH dehydrogenase. The average editing efficiencies in roots were reduced significantly compared with leaves across three varieties in both organelles. In addition, we found that the reduction of RNA editing efficiency in mitochondria is mild compared with plastid. Expression analysis further showed that an extraordinarily high percentage of RNA editing factors were down-regulated in roots, particularly for PPR, MORF proteins, indicating that the distinct editing patterns between roots and leaves might result from the differential regulation of RNA editing factors expression. This study provides references and insights into understanding the function of plant RNA editing in tissue-specific regulation mediated by editosomes.

An Overview of Compressive Trackers

Zhongyi Hu,Lei Xiao,Fei Teng 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.9

Compressive tracking is considerably popular in the visual tracking community in recent years. The very strong theoretic support from compressive sensing motivates many researchers to follow and there are a wide range of compressive trackers with attractive performances. The goal of this paper is to overview some of the most recent state-of-the-art compressive trackers in the literature. First, a variety of compressive trackers are thoroughly introduced and summarized. Second, extensive analyses from different perspectives, including random measurement matrix, compressive features, feature selection strategy and so forth, aim to provide readers a good understanding of the strengths and weaknesses of different trackers. Finally, several possible future trends for compressive trackers are outlined to hopefully bring some insights to interesting researchers.

Role of Nucleation-Promoting Factors in Mouse Early Embryo Development

Wang, Qiao-Chu,Liu, Jun,Wang, Fei,Duan, Xing,Dai, Xiao-Xin,Wang, Teng,Liu, Hong-Lin,Cui, Xiang-Shun,Sun, Shao-Chen,Kim, Nam-Hyung Cambridge University Press 2013 Microscopy and microanalysis Vol.19 No.3

<B>Abstract</B><P>During mitosis nucleation-promoting factors (NPFs) bind to the Arp2/3 complex and activate actin assembly. JMY and WAVE2 are two critical members of the NPFs. Previous studies have demonstrated that NPFs promote multiple processes such as cell migration and cytokinesis. However, the role of NPFs in development of mammalian embryos is still unknown. Results of the present study show that the NPFs JMY and WAVE2 are critical for cytokinesis during development of mouse embryos. Both JMY and WAVE2 are expressed in mouse embryos. After injection of JMY or WAVE2 siRNA, all embryos failed to develop to the morula or blastocyst stages. Moreover, using fluorescence intensity analysis, we found that the expression of actin decreased, and multiple nuclei were observed within a single cell indicating that NPFs-induced actin reduction caused the failure of cell division. In addition, injection of JMY and WAVE2 siRNA also caused ARP2 degradation, indicating that involvement of NPFs in development of mouse embryos is mainly through regulation of ARP2/3-induced actin assembly. Taken together, these data suggested that WAVE2 and JMY are involved in development of mouse embryos, and their regulation may be through a NPFs-Arp2/3-actin pathway.</P>

The Expression of Aldehyde Dehydrogenase Family in Breast Cancer

Yan Qiu,Tianjie Pu,Li Li,Fei Cheng,Changli Lu,Linyong Sun,Xiao Teng,Feng Ye,Hong Bu 한국유방암학회 2014 Journal of breast cancer Vol.17 No.1

Purpose: It is widely accepted that aldehyde dehydrogenase(ALDH) activity is a signature of breast cancer stem cells, andhigh activity has been reported to be associated with poor clinicaloutcome. The aim of this study was to assess the expressionof members of the ALDH family of isozymes in breast cancer tissuesand to evaluate the implications of the results. Methods: Weanalyzed paraffin-embedded tumor tissue from 160 patients withbreast cancer. Immunohistochemistry (IHC) staining was performedon the slides using antibodies against different ALDHfamily members. We collated the IHC results with patient clinicalcharacteristics and determined their prognostic value. In addition,we analyzed normal, hyperplastic, and carcinomatous tissues insitu to check their ALDH distributions. Results: All the testedALDH members were detected in the various tissue types, but atdifferent levels. Only ALDH 1A3 was found to be significantly associatedwith distant metastasis (p=0.001), disease-free survival(p<0.001), and overall survival (p<0.001). Conclusion: The levelof ALDH 1A3 in breast cancer tissue is a predictive marker of apoor clinical outcome.