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- 저자 : John K. L. Ho (검색결과 2 건)
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Prediction of Discharge Status and Readmissions after Resection of Intradural Spinal Tumors
Michael C. Jin,Allen L. Ho,Austin Y. Feng,Zachary A. Medress,Arjun V. Pendharkar,Paymon Rezaii,John K. Ratliff,Atman M. Desai 대한척추신경외과학회 2022 Neurospine Vol.19 No.1
Objective: Intradural spinal tumors are uncommon and while associations between clinical characteristics and surgical outcomes have been explored, there remains a paucity of literature unifying diverse predictors into an integrated risk model. To predict postresection outcomes for patients with spinal tumors. Methods: IBM MarketScan Claims Database was queried for adult patients receiving surgery for intradural tumors between 2007 and 2016. Primary outcomes-of-interest were nonhome discharge and 90-day postdischarge readmissions. Secondary outcomes included hospitalization duration and postoperative complications. Risk modeling was developed using a regularized logistic regression framework (LASSO, least absolute shrinkage and selection operator) and validated in a withheld subset. Results: A total of 5,060 adult patients were included. Most surgeries utilized a posterior approach (n = 5,023, 99.3%) and tumors were most commonly found in the thoracic region (n = 1,941, 38.4%), followed by the lumbar (n = 1,781, 35.2%) and cervical (n = 1,294, 25.6%) regions. Compared to models using only tumor-specific or patient-specific features, our integrated models demonstrated better discrimination (area under the curve [AUC] [nonhome discharge] = 0.786; AUC [90-day readmissions] = 0.693) and accuracy (Brier score [nonhome discharge] = 0.155; Brier score [90-day readmissions] = 0.093). Compared to those predicted to be lowest risk, patients predicted to be highest-risk for nonhome discharge required continued care 16.3 times more frequently (64.5% vs. 3.9%). Similarly, patients predicted to be at highest risk for postdischarge readmissions were readmitted 7.3 times as often as those predicted to be at lowest risk (32.6% vs. 4.4%). Conclusion: Using a diverse set of clinical characteristics spanning tumor-, patient-, and hospitalization-derived data, we developed and validated risk models integrating diverse clinical data for predicting nonhome discharge and postdischarge readmissions.
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Teng-Fei Xiao,Xiao-Dong Li,John K. L. Ho 제어·로봇·시스템학회 2015 International Journal of Control, Automation, and Vol.13 No.1
In this article, a novel fuzzy systems based on adaptive Iterative Learning Control (ILC) strategy is presented to deal with a class of non-parametric nonlinear discrete-time systems which perform iteration-varying reference trajectory tracking. Using the technique of fuzzy systems to compensate for the non-parametric uncertainty of the discrete-time system dynamics, the proposed adaptive ILC scheme can well track the iteration-varying reference trajectory beyond the initial time points. The convergence of the fuzzy systems based adaptive ILC algorithm is guaranteed by theoretical analysis, and a numerical example is given to illustrate the effectiveness of the adaptive ILC scheme.
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