서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

거제도(경상남도, 거제시)의 거미상

김주필(Joo Pil Kim),김대희(Dae Hee Kim),지승환(Seung Hwan Ji),지성현(Sung Hyun Ji) 한국거미연구소 2017 한국거미 Vol.33 No.2

2017년 7월 4일부터 6일까지 경상남도 거제시 거제도 일대를 김주필, 김대희, 지승환, 지성현, 최라미, 이영경 등 한국거미연구소 회원들이 주야로 채집한 결과, 총 23과 56속 75종이 조사 연구되어 이에 발표하는 바이다. 채집한 표본은 주필거미박물관에 보관하였다. From July 4 to 6 in 2017. Joo-Pil Kim, Dae-Hee Kim, Seung-Hwan Ji, Sung-Hyun Ji, Ra-Mi Choi, Yeong-Gyeong Lee, the members of The Arachnological Institute of Korea investigated the spiders in the whole area of Geoje city, Geoje-do, Gyeongsangnam-do and report 23 Family 56 Genus 75 Species of spiders. The collected spiders are placed (stored) in the Joo-Pil Spider museum.

신속한 재전송을 이용한 슬라이딩 윈도우 프로토콜

김필중,김상하 충남대학교 기초과학연구소 1996 忠南科學硏究誌 Vol.23 No.2

Good performance of the data link layer which is using sliding window protocol requires selection of optimal timeout duration. Timeout duration can be selected based on RTT. But, due to the variable environmental factors of channels, selection of optimal timeout duration is not easy task. This paper suggests additional method that can be used to identify frame loss even before timeout occurs. Using this additional method(called Fast Retransmission method), sender detects transmission error on a certain frame early and retransmits the frame immediately without further waiting for timeout event. This method loosen up the requirement of stringent timeout value on data link layer and gives the performance quite closed to the one that can be obtained with optimal timeout value.

소아 동종 조혈모세포이식 200예의 분석 : Single Center Study

김학기,조빈,정낙균,정대철,장필상,김선영,김춘추 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.1

연구배경: 1983년 11월부터 2000년 9월까지 시행한 동종 조혈모세포이식의 성적을 분석하여 소아 골수이식의 발전 방향을 모색하고자 하였다. 방법: 1983년 11월부터 2000년 9월까지 가톨릭의대 조혈모세포이식센터, 성모병원 소아과에서 동종 조혈모세포이식을 시행한 200예를 대상으로 조혈모세포이식의 유형 및 대상질환, 이식 당시의 상태 및 전처치에 따른 치료 성적을 후향적으로 분석하였다. 결과: 200예 중 HLA-일치 형제간 골수이식이 146예(73%), HLA-일치 형제간 골수이식 이외의 이식이 54예(27%)였다. 1) HLA-일치 형제간 골수이식: 146예 중 남아와 여아가 각각 78명과 68명이었으며 SAA 50예의 5년 무병 생존율은 95.8±2.9%였고 AML 45예의 5년 무병 생존율은 71.7±7.0%로 일차 및 이차 관해기에 이식 받은 40예와 5예의 5년 무병 생존율은 각각 73.6±7.2%와 60.0±21.9%였다. AML에서 전처치로 Bu/Cy를 사용한 28예와 TBI/Cy를 사용하였던 9예의 5년 무병 생존율은 각각 81.9±7.4%와 33.3±15.7%였으며 Bu/Cu/TBI를 시행한 8예의 무병 생존율은 80.0±17.9%였다. ALL 33예의 5년 이상 무병 생존율은 75.5±7.5%였고 일차 및 이차 관해기에 이식을 시행하였던 18예와 14예의 무병 생존율은 각각 83.0±9.0%와 71.4±12.1%였다. CML 및 MDS 11예의 5년 무병 생존율은 72.7±13.4%였다. 기타 질환으로는 Fanconi 빈혈 2예, 혈구탐식성 조직구증식증 2예, 순적혈구 빈혈 2예, Kostmann 증후군이 1예로 이들의 전체 무병 생존율은 85.7±13.2%였다. 2) HLA-일치 형제간 골수이식 이외의 이식을 시행하였던 54예의 3년 이상 무병 생존율은 45.3±11.6%였으며 HLA-일치 UBMT 26예, CBSCT 15예, 형제 이외의 혈연에 의한 골수이식이 13예로 이들의 무병 생존율은 각각 56.2±10.8%, 58.2±13.1%, 35.9±17.3%였다. 결론: 소아 난치성 혈액질환의 완치요법으로 동종 골수이식의 치료효과를 확인할 수 있었으며, 동종 조혈모세포의 공여원으로 비혈연간 골수나 제대혈의 이용이 점차 증가하고 있음을 알 수 있었다. Background: Bone marrow transplantation was first introduced to Korean children in 1983. Since then the number of children receiving transplants has increased steadily. Methods: We analyzed two hundred pediatric cases of allogeneic hematopoietic stem cell transplantation between Nov. 1983 and Sep. 2000 in Catholic Hematopoietic Stem Cell Transplantation Center of Korea. Results: HLA-matched sibling transplantations were performed in 146 cases (78 males, 68 females, median age; 10 years) with median follow-up of 47 months. The 3-year estimated event-free survival (EFS) of ALL and AML was 76% and 72% respectively. The 5-year estimated EFS of severe aplastic anemia and CML/MDS was 96% and 73% respectively. The 2-year estimated EFS of nonmalignant rare disease was 86%. Twenty-six children underwent unrelated bone marrow transplantation (UBMT), 15 cord blood stem cell transplanta-tion (CBSCT) and 13 familial haploidentical transplantation (FHT). There were 35 males and 19 females with a median age of 6.5 years and median follow-up of 18.5 months. The estimated 2-year EFS of UBMT, CBSCT and FHT were 56%, 58% and 34% respectively. Conclusion: HLA-matched sibling allogeneic BMT showed better survival in children with hematopoietic stem cell disorder compared to UBMT and CBSCT. Recently, transplants using alternative stem cell source are increasing due to lack of suitable matched sibling donor and continuous efforts for reducing transplant-related complications are warranted for improving survival.

국제 신뢰성 표준화에 관한 조사 연구

김종걸,강성필 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(1)

본 논문은 IEC의 구성, 조직 및 규격에 관한 조사연구와 IEC의 국제 규격 제정 및 개정 절차 등의 조사 연구를 통하여 현재 우리가 필수적으로 갖추어야 할 신뢰성 표준들이 무엇인지를 제시하고, 신뢰성 표준화 사업 및 인증 사업에 관한 방향을 제시하고자 한다. 이를 바탕으로 적정하고 합리적인 신뢰성 표준화 사업이 전개되어 서비스의 향상, 생산기술의 혁신을 기하여 산업경쟁력을 향상시킬 것이다.

화일 정보를 효율적으로 제공하는 화일 화인더의 구조 설계

김필중,김상하 충남대학교 기초과학연구소 1995 忠南科學硏究誌 Vol.22 No.1

One of the most compelling problems facing local area networks is the location information of resources on the networks. This paper explores the network architecture of file finders which is suitable for retrieving the resource information efficiently. Each network file finder is composed of four functions: registration, management, retrieval, and network functions. The communication between network file finders may be required to get the correct resource information because all informations are distributed over them. This may cause the loop problem in which the service request may be routed to the request generator itself. This problem could be sloved by the spanning tree method in this paper.

응급실을 내원한 요로결석 환자

김성중,김준식,조준필 대한응급의학회 1995 대한응급의학회지 Vol.6 No.1

A clinical study was made on 139 cases of urolithiasis among the total number of 14798 who visited in the emergency center during 7 months from June 1994 to December 1994.The 186 patients was suspected the urolithiasis, then the 150 patients was followed through out-patient department of Urology and performed Intravenous pyelogram. Among the 150 cases, the urolithiasis was confirmed in 139 cases. The results are summarized as follows: 1. The ration of the male to female is approximately 2.97:1. 2. The age of the patients ranged from 20 to 50 in approximately 80.6%. 3. Among 52 patient who were not revealed stone in KUB, 45 patients were shown micro-scopic hematuria. The 22 patients were revealed urolithiasis in IVP.The 6 patients found the urolithiasis spontaneously delivered.The 17 patients were diagnosed through out-patient department of urology. 4. The 7 patients, who not hematuria and no stones in KUB, were revealed urolithiasis in IVP performed at other hospital. 5. The major clinical symptoms and signs were flank pain(117 cases),abdominal pain and suprapublic discomfort(35 cases),fever(7 cases),low back pain(7 cases),nausea and vomiting(6 cases),painful urination(1 case),and urinary frequency(1 case). 6. The specific location of the stones showed 98 cases in ureter, 7 cases in kidney,bilaterality(3 cases),and multiple stones(8 cases). The ureteral stones located most frequently in the lower 1/3 of the ureter with 55 cases.

돈지, 들깨유 및 달맞이꽃 종자유의 혼합급이가 흰쥐의 혈청 지질 성분에 미치는 영향

김성희,김한수,강정옥,박필숙,정승용 慶尙大學校 1992 論文集 Vol.31 No.2

돈지 및 들깨유와 달맞이꽃 종자유등 2종 식물 종자유아의 혼합비율을 달리한 유지의 급이가 흰쥐의 혈청 지질성분에 미치는 영향을 구명하기 위해 S·D계 숫쥐에게 돈지 2.5% 및 들깨유와 달맞이꽃 종자유의 혼합비율을 달리하여 4주간 급이 사육한 후 혈청의 지질 성분을 분석 검토한 결과는 다음과 같다. 혈청의 총콜레스테롤 농도는 대조군(A군 돈지10%)에 비해 B군(들깨유7.5%+돈지2.5%)이 유의적으로 낮았으며, HDL-콜레스테롤 농도는 대조군에 비해 C군(들깨유 5.0%+달맞이꽃 종자유2.5%+돈자2.5%), D군(들깨유 2.5%+달맞이꽃 종자유5.0%+돈지2.5%)및 E군(달맞이꽃 종자유7.5%+돈자2.5%)이 높았고, 총콜레스테롤에 대한 HDL-콜레스테롤의 농도비는 대조군에 비해 E군이 현저하게 높았다. 콜레스테롤를 급이군은 콜레스테롤 무급이군에 비해 전 군에 걸쳐 총콜레스테롤 농도는 월등히 높았고 HDL-콜레스테롤 농도는 낮았다. 콜레스테롤 에스테르의 농도는 대조군에 비해 B및 C군은 낮은 반면, D및 E군은 높았고 콜레스테롤 급이군에 비해서는 대조군에 비해 전군이 유의적으로 낮았다. LDL및 LDL-콜레스테롤 농도는 대조군에 비해 전 군이 유의적으로 낮았으며 B군은 특히 현저하게 낮은 경향을 나타내었고, 또한 콜레스테롤 급이군은 콜레스테롤를 무급이군과 유사한 경향을 보였으나 전반적으로 월등하게 높았다. 인지질 및 중성지질의 농도는 대조군에 비해 전 군이 유의적으로 낮게 나타났고, 콜레스테롤 급이군의 혈청 중 인지질 및 중성지질의 농도는 콜레스테롤 무급이군고 유사한 경향이였으나 전반적으로 보아 현저하게 낮았다. In order to observe the effects of the feeds mixed with the lard and two vegetable seeds oils on lipid components of serum in rats, the oils mixed with 2.5% lard and various level of perilla oil and evening primrose oil were administered to the male rats of the S.D. for 4 weeks. Total cholesterol concentrations of serum were significantly lower in the B group(perilla oil 7.5%+ lard 2.5%) than in the control group(A group ,lard 10%). HDL-cho-lesterol concentrations in serum were higher in the C(perilla oil 5.0%+evening primrose oil 2.5%+lard 2.5%), D(perilla oil 2.5%+evening primrose oil 5.0%+lard 2.5%) and E(evening primrose oil 7.5%+lard 2.5%) groups than in the control group. In the supplemeted cholesterol groups(SC groups), total cholesterol concentrations in serum were by far higher and HDL-cholesterol concentrations in serum were lower than in the nonsupplemented cholesterol groups(NSC groups). Cholesteryl ester concentrations in serum were lower in the B and C groups, but higher in the D and E groups than in the control group. In the SC groups, cholesteryl ester concentrations in serum were significantly lower in the other groups than in the control group. concentrations of LDL-cholesterol in serum were lower in the other groups and remarkably in SC groups were similar to the NSC groups, but those of serum were by far higher in all groups. Concentrations of phospholipid and triglyceride in serum were significantly lower in the other groups than in the control group, in the SC groups, concentrations of phospholipid and triglyceride were similar to the NSC groups, but those from serum were remarkably lower in all groups.

응급실 내원시 예상치 못한 사망 환자의 예측 인자

김욱진,서정필,정성필,황태식,이한식 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

Background: Unexpected deaths of the patients at ED are surprising to the medical staffs as well as the families. It may also increase the possibilities of medico-legal problems. This study was conducted to review the unexpected death in ED and find the predictive factors leading patients to unexpected death. Methods: A retrospective study with reviewing available medical records of 183 patients who were expired at Ed of Shinchon Severance Hospital from Mar. 1997 to Feb. 1998 and 103 patients of Youngdong Severance Hospital from Mar. 1996 to Feb. 1998 was done. Analyses were done on 30 variables of physical findings, laboratory results, procedures and therapies. We used univariate analysis such as t-test and x²-test and multiple logistic regression analysis. Results: Of the total 286 deaths in Ed, 153 cases were enrolled in this analysis. The number of unexpected deaths were 76. Age, mental status, fraction of neutrophil count, BUN level, whether endotracheal intubation was done, use of inotropics were the factors with statistical significance on the univariate analysis, but only comatose mentality, endotracheal intubated case, and use of the inotropics were significant on logistic regression analysis. The longer the ED length of stay, the higher the rate of mortality and unexpected death. Conclusion: This result suggest that medical attention is needed on the patients with comatose decreased mental status, endotracheally intubated case and needing inotropic agents to prevent unexpected deaths shortening the ED length of stay may also be a factor for decrease the unexpected death rate.

형광백혈구 안저촬영술에서 플로레신 염색의 안정성과 형광림프구의 분리

김윤희,강필성,김강주,양연식,김재덕 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.1

Recently, retinal blood flow has been studied with several methods, targeted dye delivery method, fluorescent vesicle system, laser Doppler velocimetry, acridine orange staining method. Authors presented a new method, fluorescein leukocyte angiography using a scanning laser ophthalmoscope which include external staining of leukocyte with fluorescein dye and reintroduce the fluorescent leukocyte into the blood flow. Authors tried to check security of external fluorescein staining of leukocytes and separation of fluorescent lymphocytes from whole blood and supernatant fluid using Ficoll-Paque, with cell viability, leukocyte recovery rate and erythrocyte contamination rate. There was no significant difference in cell viability, leukocyte recovery rate and erythrocyte contamination rate between fluorescein staining group and non-staining group. Fluorescent lymphocytes could be separated from whole blood and supernatant solution after gravity sedimentation with 6% hetastarch and the gravity sedimented group had low erythrocyte contamination rate than whole blood group(p≤0.05). In conclusion, external fluorescein staining procedure of leukocyte during fluorescein leukocyte angiography could be performed without cell injury compared to non-fluorescein staining group and fluorescent lymphocyte could be separated from whole blood and supernatant fluid after gravity sedimentation.