고등급 이형성을 보인 편평톱니샘종

권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1

Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.

사이버 가정학습체제 구축 모형 개발

권성호,최인호,심현애,이승진,김경현,장상현 한국교육정보미디어학회 2003 교육정보미디어연구 Vol.9 No.4

본 연구는 초·중등 사이버 가정학습체제의 구축 모형 개발을 목적으로 한다. 이를 위해 첫째, 사교육비 관련 현황 및 우리나라의 사회·현실적 요구를 분석하고, 둘째, 사이버 공간에서의 학습을 지원하는 학습이론을 탐색하여 얻은 시사점을 바탕으로 사이버 가정학습체제 개발 원리를 도출하였으며, 셋째, 학습이론적 적용의 틀을 기반으로 사이버 가정학습체제 구축 모형을 개발하고, 각 모형에 대한 세부적인 설명과 시행 시 고려해야 할 사항을 제시하였다. 사이버 가정학습체제 구축 모형은 체제 구성요소와 각 요소들 간의 관계를 도식화한 체제 구성도를 바탕으로 사이버 가정학습체제를 운영하는 활동 주체들의 역할을 정의한 운영 모형, 사이버 가정학습체제 내에서의 학습 유형과 흐름을 보여주는 학습 모형, 사이버 가정학습체제 내 학습 콘텐츠의 구성 기준을 제시하는 콘텐츠 모형 그리고 사이버 가정학습체제 내에서의 학습에 대한 학업성취도 평가와 체제 평가를 위한 평가 모형으로 구성되었다. 각 유형별 모형은 필요에 따라 하위 모형으로 분류되어 총 17개의 사이버 가정학습체제 모형을 제시하였다. 또한 사이버 가정학습체제가 사교육비 절감과 공교육 지원이라는 궁극적인 목적을 달성하기 위해 고려되어야 할 시사점으로 환경자원, 학습자원, 인적자원, 홍보 마케팅 등의 네 가지 측면으로 나누어 제시하였다. The study is purposed to develop a set of construction models for Cyber Home Study System(CHSS) to support the students' self study through internet at the level of elementary, middle and high school students. This is intended to reduce the over spending of the private educational payment, causing the social conflict and antagonism in Korea, and finally to support the public education. The study problems are as follows: 1. Analysis on the social and authentic needs for reducing the private educational payment which causes the social conflict and antagonism in Korea. 2. Setting up the principles to develop the construction model for CHSS to apply the learning theories in support of the learning in the cyber space. 3. Development of a set of construction models for development and construction for CHSS, based on the theoretical developmental principles. The construction model for CHSS developed in this study contains a systemic diagram of the whole CHSS, and 4 major models: a model for management, the model for learning process, the model for content design, and the model for evaluation. The systemic diagram for CHSS demonstrates various components, which consist of the whole system, and the relationship among the components. The model of management identifies the role of each organization by which the CHSS is operated. The Learning process model is classified with 9 sub-models converging on the three factors. These factors are the learner subject, the existence of tutor support, and the relationship to the local school. The models for content design proposes the guideline for design and production of learning content. The evaluation model is composed of three sub models: evaluation for individual learning achievement, evaluation for learning achievement of the tutor supported calss members, and the system evaluation. Finally, 4 kinds of suggestions is suggested to accomplish the purpose of CHSS in terms of environmental resources, learning resources, man power, and advertising and marketing strategies.

초등학교 급식소에서의 HACCP 적용을 위한 계절별 환경미생물학적 위해분석

권성희,이헌옥,정덕화,신원선,엄애선 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.5

Foodservice at elementary schools has been povided nation-wide. It is predictable that foodborne diseases would increase continuously. Formation of a counterplan is urgently needed. This study was designed to identify the stage which contains the critical control points (CCPs) for the microbiological management of HACCP(Hazard Analysis Critical Control Point) at the foodservice provided at elementary schools. Foodservice places at four elementary schools in Seoul were sampled and the overall hygiene of cooking, utensils and equipment, employees, and environment by season were examined. The results showed that the number of bacteria in overall samples was increased and that E. coli, Salmonella and Staphylococcus by biochemical test emerged in more diverse samples in summer than in spring. Particularly, the number of aerial bacteria in summer was three-fold greater than that in either spring or winter. E. coli 0157 was not detected, although Salmonella was identified by PCR analysis in the meat Knives, chopping boards, waste bins and meat dish at elementary school foodservice. According to this data, cross-contamination should be managed in the stage of mixing up the ingredients with improper equipments and insanitary treatments. Thus, the establishment of SSOP (Sanitation Standard Operating Procedures) and GMP (Good Manufacturing Practice) at elementary school foodservice is stringently required, along with sanitation education for workers and employees as CCPs.

갯쑥부쟁이(Heteropappus hispidus (Thunb.))의 감마방사선 감수성과 M1 세대 형질변동 특징

오병권,홍경애,송성준,유장걸,이선주,이영일 제주대학교 방사능이용연구소 2003 연구보고 Vol.17 No.-

제주도에서 자생하는 갯쑥부정이(Heteropappus hispidus(Thunb.))에 감마선을 10, 20, 40, 80, 120, 160, 200, 300, 400Gy 수준으로 나누어서 조사한 뒤 발아율 및 발아 30일 후의 본엽 출현을, LD_(50), 본엽길이, 줄기부분의 안토시아닌 색소 형성 유무, 생육 60일 후의 로젯형 엽, multi-shoot 형성율, 초장, 채화 결실율등의 주요 양적형질들을 생존개체를 대상으로 실시하였다. 120Gy 까지의 발아율은 88.5%로 대조구와 큰 차이를 보이지 않았으나 160Gy 이상에서 부터는 급격히 감소하여 치사선량(LD_(50))은 160Gy 범위 정도였다. 또한, 본엽 출연율과 그 길이는 조사선량이 높아질수록 억제되었다. 안토시아닌 색소 형성은 조사전량이 높을수록 대조구 2%에서 30%로 높아졌으며 로젯형도 고선량 처리구에서 발생하였다. Multi-shooting은 80Gy 이상일 때 부터 나타났으며 multi-shooting을 형성하는 개체들은 초장은 짧고 줄기는 가늘게 다발형으로 자라는 특성이 있어서 만일 형질이 고정된다면 화분 관상용 개체로 선발하기에 적합하였다. 특히, 조사선량이 증가됨에 따라서 안토시아닌 색소 형성, 로젯형 개체, multi-shoot등의 개체가 많이 출현되었는데 이는 돌연변이 유기의 선발지표가 될 수 있을 것으로 보인다. The seeds of naturally growing Heteropappus hispidus Thunb were treated by nine different doses(0, 10, 20, 40, 80, 120, 160, 200, 300, 400㏉) of gamma rays to investigate their germination rate and to quantify the characteristics of their germinated plant as like as leaf appearance and length, the formation rate of anthocyanin color in stem 30 days after germination, the formation rate of rosette leaf and multi-shoot, the flowering and seed-bearing, and shoot length. The germination rate at least up to 120 ㏉ was not greatly affected but was rapidly decreased at over 160 ㏉. It seemed that lethal dose(LD_(50)) of germination was 160 ㏉. The leaf appearance and growth was also inhibited, but the formation rate of anthocyanin color in the flower stem was enhanced up to 30% with dose. The rosette plants were observed in plants irradiated with higher than 40 ㏉. Multi-shoots were developed over 80 ㏉. For a short shoot length and bundle of thin stem, it was considered that they can be selected as the potential pot flower plants, through genetic fixation. In particular, it was suggested that the formation of anthocyanin color in flower stem, rosette and multi-shoot plants induced by the morphologically markers for the mutant selection of Heteropappus hispidus (Thunb.)

다형성 교모세포종에서 광범위 전적출술후 단기 재발된 치험 1예

박호권,강중식,조준,문창택,장상근,임정애 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

Glioblasty/ma Multiforme(GBM) is the one of the most common malignant tumors in central nervous system(CNS). The incidence of the tumor is about 12% of all CNS tumors and about 50% of all intracranial tumors. Though the development of the microsurgical technique, radiosurgical technique, and chemotherapy works effectively, complete cure of the GBM has not been achieved. It has been known that the prognosis of GBM depends on the extent of surgical tumor removal, remained tumor volume, radiation dose, and chemotherapy. Not only patient's age but also tumor characteristics such as MRI enhancement, angiogenesis and necrosis are also very important prognostic factors. Authors experienced very aggressive GBM in aged woman, who received gross total tumor removal, but refused other therapeutic motalities postoperatively. Very rapid recurrence of GBM and global cerebral edema in aged woman should be considered fatal. This case demonstrates the effectiveness of aggressive removal and the limited usefulness of neurosurgical tools in GBM recurrence. Authors would suggest that the early diagnostic effort and the verified neurosurgical therapy for malignant tumor are still strongly requested to make better prognosis.

삶의 질 향상과 지속가능한 지역경쟁력 : 호순환 관계의 모색

장지상,이성진,조정재,권우현,김애경 慶北大學校 1997 經商論集 Vol.25 No.1

갯쑥부쟁이(Heteropappus hispidus (Thunb.))의 감마방사선 감수성과 M1 세대 형질변동 특징

오병권,홍경애,송성준,유장걸,이선주,이영일 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

제주도에서 자생하는 갯쑥부쟁이(Heteropappus hispidus (Thunb.))에 감마선을 10, 20, 40, 80, 120, 160, 200, 300, 400 Gy 수준으로 나누어서 조사한 뒤 발아율 및 발아 30일 후의 본엽 출현율, LD_(50), 본엽길이, 줄기부분의 안토시아닌 색소 형성 유무, 생육 60일 후의 로젯형 엽, multi-shoot 형성율, 초장, 개화 결실률 등의 주요 양적형질들을 생존개체를 대상으로 실시하였다. 120 Gy 까지의 발아율은 88.5%로 대조구와 큰 차이를 보이지 않았으나 160 Gy 이상에서 부터는 급격히 감소하여 치사선량(LD_(50))은 160 Gy 범위 정도였다. 또한, 본엽 출현율과 그 길이는 조사선량이 높아질수록 억제되었다. 안토시아닌 색소 형성은 조사선량이 높을수록 대조구 2%에서 30%로 높아졌으며 로젯형도 고선량 처리구에서 발생하였다. Multi-shooting은 80 Gy 이상일 때 부터 나타났으며 multi-shooting을 형성하는 개체들은 초장은 짧고 줄기는 가늘게 다발형으로 자라는 특성이 있어서 만일 형질이 고정된다면 화분 관상용 개체로 선발하기에 적합하였다. 특히, 조사선량이 증가됨에 따라서 안토시아닌 색소 형성, 로젯형 개체, multi-shoot등의 개체가 많이 출현되었는데 이는 돌연변이 유기의 선발지표가 될 수 있을 것으로 보인다. The seeds of naturally growing Heteropappus hispidus (Thunb.) were treated by nine different doses (0, 10, 20, 40, 80, 120, 160, 200, 300, 400 ㏉) of gamma rays to investigate their germination rate and to quantify the characteristics of their germinated plants as like as leaf appearance and length, the formation rate of anthocyanin color in stem 30 days after germination, the formation rate of rosette leaf and multi-shoot, the flowering and seed-bearing, and shoot length. The germination rate at least up to 120 ㏉ was not greatly affected but was rapidly decreased at over 160 ㏉. It seemed that lethal dose (LD_(50)) of germination was 160 ㏉. The leaf appearance and growth was also inhibited, but the formation rate of anthocyanin color in the flower stem was enhanced up to 30% with dose. The rosette plants were observed in plants irradiated with higher than 40 ㏉. Multi-shoots were developed over 80 ㏉. For a short shoot length and bundle of thin stem, it was considered that they can be selected as the potential pot flower plants, through genetic fixation. In particular, it was suggested that the formation of anthocyanin color in flower stem, rosette and multi-shoot plants induced by the high dose of gamma rays could be utilized as the morphological markers for the mutant selection of Heteropappus hispidus (Thunb.).

소규모 베이커리에서의 HACCP적용을 위한 미생물학적 위해도 평가

엄애선,권성희,정덕화,오상석,이헌옥 한국조리과학회 2003 한국식품조리과학회지 Vol.19 No.4

Recently, the HACCP(Hazard Analysis Critical Control Point) system has been emphasized in food processing industries throughout the world. However, the system has, as yet, not been applied very well to domestic food industries. Due to the increase in the consumption of bakery products, more studies are required on the application of HACCP to establish the system in small-scale bakeries. This study was designed to provide basic data for setting management standards for HACCP, based on microbiological hazard evaluations of bakery products. Red bean paste filled breads, custard cream filled breads and cakes covered with fresh whipping cream were collected, and microbiological evaluations conducted on the raw materials, the manufacturing processes and potential hazards. The result showed the presence of coliforms in fresh cream of cakes and the soybean paste of soybean paste breads at levels as high as 105 CFU/g on the hazard analysis of the raw materials. Moreover, the general levels of bacteria and coliforms were over those of the standards during the intermediate fermentation and molding processes. Furthermore, high levels of coliforms were detected on the hands of the salesmen and bakers themselves. This suggests that the CCPs (Critical Control Points), such as fresh cream and red bean paste manufacturing process desperately require better management. There is also a requirement for education relating to personal hygiene for the production of hygienic bakery products and for the publics health.

청소년 볼링 선수들의 경기 대처 기술요인 분석

이영애,유승준,이용식,신철호,현승권 한국학교체육학회 2002 한국학교 체육학회지 Vol.12 No.2

본 연구는 청소년 볼링 선수들의 경기 대처 기술 요인의 구조를 밝히는 것으로 이를 바탕으로 볼링선수들의 성공적인 수행을 예상하여 경기력을 향상 시키는데 그 목적이 있다. 이러한 연구목적에 맞추어 본 연구는 우수선수와 비 우수선수의 심리적 기술 요인을 측정하기 위하여 Smith, Schutz, Smoll, Ptacek(1995)에 의해 개발된 선수들의 대처기술(ACSI-25: the Athletic Coping Skills Inventory-28)척도를 국내 실정에 맞게 번안하여 심리측정적 타당도를 검증한 후 사용하였다. 각 요인별 타당도와 신뢰도를 화보하기 위하여 요인분석을 실시한 결과 16문항 6요인으로 분류되었으며, 분류된 6개의 심리기술 요인을 성취욕구, 걱정, 코칭능력, 목표설정, 역경대처, 집중력으로 명명하였다. 이 후 각각의 배경변인(성별, 우수여부, 학년)에 따른 각 요인별로 three-way MANOVA분석 결과 6개 요인에 대한 배경변인의 차이는 발견되지 않았다. This study aims to provide information on how to improve bowlers capacity by examining amateur bowlers athletic coping skill factors. A test paper on the Athletic Coping Skills Inventory-28(ACSI-28) developed by Smith, Schutz, Smoll, and Ptacek(1995) is used in order to measure the athletic coping skill factors of excellent as well as mediocre players. This paper is adapted for the domestic situation, with its appropriateness for measuring the bowlers mental state verified. Crombach's α result is used in classifying 16 questions and 6 factors, with factor analysis done in order to secure the appropriateness and credibility by each factor The six factors are: accomplishment desire, worry, coaching ability, goal setting, coping with adversity, and concentration, A statistic analysis is then conducted according to environmental variables such as sex, excellence, and grade. Based on the analysis, the following conclusions are derived: The factor analysis reveals six athletic coping skill factors of bowlers, e,g,, accomplishment desire, worry, coaching ability, goal setting, coping with adversity, and concentration. A three-way MANOVA analysis per three environment variables (sex, grades, and excellency) for the six athletic coping skill factors (accomplishment desire, worry, coaching ability, goal setting, coping with adversity, and concentration) reveals that environment variables do not cause any difference in the psychological technique factors of bowlers. In order to verify the effect of a bowlers maturity on the six athletic coping skill factors (accomplishment desire, worry, coaching ability, goal setting coping with adversity, and concentration), multiple regression analysis is done with a multi-step method, using predicative variables and athletic coping skill factors as reference variables. The result shows that the bowlers level of maturity is evident in goal setting and coping with adversity.

「장애인 등에 대한 특수교육법」에 따른 교육과정적 통합교육 실시에 대한 초등학교 특수교사와 일반교사의 인식

김의정,김애화,최혜승,권택환 이화여자대학교 교과교육연구소 2011 교과교육학연구 Vol.15 No.4

본 연구에서는 .장애인 등에 대한 특수교육법.에 따른 교육과정적 통합교육 실시에 대한 초등학교 특수교사와 일반교사의 인식을 알아보기 위하여 포커스 그룹 인터뷰를 실시하였다. 총 30명의 교사(특수교사 15명과 일반교사 15명)가 포커스 그룹 인터뷰에 참여하였고, 인터뷰는 5개의 개방형 질문에 따라 진행되었다. 인터뷰 데이터를 전사한 후 3차에 걸쳐 코딩하였으며, 이를 통해 .장애인 등에 대한 특수교육법.에서 요구하는 교육과정적 통합교육 실시에 대한 특수교사와 일반교사의 인식과 관련된 4개의 주제와 이들 주제 하에 특수교사 13개, 일반교사 16개의 범주가 도출되었다. 주요 연구 결과를 요약하면 다음과 같다. 첫째, 통합교육에 대한 특수교사와 일반교사의 견해에 차이가 있었다. 둘째, 교육과정적 통합교육을 실시하는 데 있어서의 어려움, 요구 사항 및 해결방안에는 특수교사와 일반교사 간 공통점과 차이점이 동시에 나타났다. 셋째, 교육과정적 통합교육을 위해 필요한 특수교사와 일반교사 고유의 전문성에는 두 교사 집단 간 뚜렷한 인식의 차이가 있는 것으로 나타났다. 마지막으로, 특수교사와 일반교사는 기본적인 교사로서의 사명감 및 자질을 교육 과정적 통합교육을 실시하는데 필요한 특수교사와 일반교사 공통의 전문성으로 인식하는 것으로 나타났다. In this study, focus group interviews were conducted to explore the perceptions of elementary special and general education teachers on curricular inclusion. Thirty teachers (15 special education teachers and 15 general education teachers) participated in focus group interviews; the interviews involved five open-ended questions. The interview data were transcribed, and then coded three times. Through the coding processes, four themes with thirteen sub-categories emerged for the special education teachers; sixteen sub-categories emerged for the general education teachers. The major findings of this study are summarized as follows. First, the special and general education teachers perceived inclusion differently. Second, the findings revealed both commonalities and differences between the special and general education teachers about difficulties, needs, and solutions for curricular inclusion. Third, the special and general education teachers felt that the unique expertise of both special and general education teachers is needed for successful curricular inclusion. Lastly, they felt that the commitment and qualities of teachers should be their common expertise in the implementation of curricular inclusion.