우리나라 長壽者의 生活 및 意識調査에 관한 硏究 - Ⅴ. 過去의 健康疾病 및 苦痛에 대한 態度 -

최진호(Jin-Ho Choi),변재형(Jae-Hyeung Pyeun),최재수(Jae-Sue Choi),임채환(Chae-Hwan Rhim),김수현(Soo-Hyun Kim),김정한(Jeung-Han Kim),이병호(Byeung-Ho Lee),우순임(Soon-Im Woo),최선남(Sun-Nam Choi),변대석(Dae-Seok Byun),김무남(Mu-Nam Ki 한국식품영양과학회 1987 한국식품영양과학회지 Vol.16 No.4

우리나라 長壽者의 生活 및 意識調査硏究의 一環으로 長壽者의 過去의 健康, 疾病 및 苦痛에 대한 對處態度 등을 調査ㆍ比較한 結果는 다음과 같다.<br/> 1. 更年期(40~60歲)의 健康狀態가 『대단히 건강했다.』가 71.0%로 가장 많고, 그 다음이 『건강이 보통이었다』가 21.6%로서, 전체 장수자의 91.6%가 보통이상의 건강상태를 유지했다.<br/> 2. 老年期에 접어든 후 疾病이나 負傷을 당한 經驗이 『없었다』고 대답한 경우가 74.7%로 대부분을 차지한 반면 『있었다』고 대답한 경우는 22.6%에 불과했다.<br/> 3. 疾病이나 負傷이 『있었다』고 한 경우의 內譯을 比較하여 보면 『消火器疾患』이 32.6%로 가장 많고, 그 다음이 『腦率中ㆍ高血壓』 14.0%, 『心臟病』 14.0%, 『呼吸器疾患』 12.8%의 순으로 되어 있었다.<br/> 4. 苦痛에 대한 經驗을 調査하여 본 結果, 苦痛이 『없었다』가 55.7%, 『있었다』가 44.3%로 거의 비슷한 傾向이었고, 苦痛에 대한 經驗內譯을 보면 『가정생활』이 85.1%로 대부분을 차지한 반면 『사업』 등은 10.1%에 불과해서 가정생활에 많은 문제가 있었음을 알 수 있었다.<br/> 5. 苦痛에 대한 對處態度롤 比較하여 보면 빨리 『잊을려고 努力했다』가 51.2%로 가장 많았고 그 다음이 『계속 걱정을 했다』(33.3%), 『걱정을 하지 않았다』(7.1%)의 순이었다.<br/> 6. 長壽한 사람들의 初經年齡은 『16~18歲』가 38.8%로 가장 많고, 그 다음이 『19歲이후』가 25.2%로서 전체 장수자의 64.0%가 16세이상에서 初經이 나타났으며, 閉經年齡은 『41~43歲』가 36.4%로 가장 많고, 그 다음이 『44~46歲』가 28.5%로서 전체 장수자의 64.9%가 46歲이하에서 閉經現象이 나타났다. 따라서 장수한 사람들의 初經年齡은 현재보다 4~5年 늦은 반면 閉經年齡은 현재보다 4~5年 빨랐음을 알 수 있었다. The present study was designed to be link a part of the research on the investigation on daily life and consciousness of the longevous people in Korea, and to investigate the health conditions, and the attitude on disease and suffering of longevous people in the past.<br/> 1. By the health conditions of longevous people between 40 and 60 years, "very good" showed the highest figure of 71.0%, followed by "ordinary" (21.6%). Consequently it is found that 92.6% of total longevous people surveyed maintained the good health conditions above ordinary.<br/> 2. Of the experiences of disease and/or injury after 60 years of longevous people, "never" showed the highest figure of 74.7%, while "had" showed the only 22.6% of total longevous people surveyed.<br/> 3. Of the details of disease and/or injury after 60 years of longevous people, "digestive disease" showed the highest figure of 32.6 %, followed by "apoplexia cerebri & hypertensions" (14.0%) and "heart disease" (14.0%), and followed by "respiratory disease" (12.8%).<br/> 4. Of the experiences of suffering between 40 and 60 years of longevous people, "never" showed 55.7% of total longevous people surveyed, while the frequency of suffering decreased in the order of "once" (22.7%), "2 times" (15.8%) and "3 times" (4.7%). By the details of suffering between 40 and 60 years of longevous people, "family life" showed the highest figure of 85.1%. followed by "business" (10.1%).<br/> 5. By the attitude on suffering of longevous people, "tried to forget soon" showed the highest figure of 51.2%, followed by "continuous worried" (33.3%). and followed by "not worried" (7.2%).

우리나라 長壽者의 生活 및 意識調査에 관한 硏究 - Ⅴ. 過去의 健康疾病 및 苦痛에 대한 態度 -

최진호(Jin-Ho Choi),변재형(Jae-Hyeung Pyeun),임채환(Chae-Hwan Rhim),양종순(Jong-Soon Yang),김수현(Soo-Hyun Kim),김정한(Jeung-Han Kim),이병호(Byeong-Ho Lee),우순임(Soon-Im Woo),최선남(Sun-Nam Choe),변대석(Dae-Seok Byun),김무남(Mu-Nam 군산대학교 수산과학연구소 1994 군산대학교 수산과학연구소 연구논문집 Vol.1 No.-

The present study was designed to be link a part of the research on the investigation on daily life and consciousness of the longevous people in Korea, and to investigate the health conditions, and the attitude on disease and suffering of longevous people in the past. 1. By the health conditions of longevous people between 40 and 60 years, ""very good"" showed the highest figure of 71.0%, followed by ""ordinary"" (21.6%). Consequently it is found that 92.6% of total longevous people surveyed maintained the good health conditions above ordinary. 2. Of the experiences of disease and/or injury after 60 years of longevous people, ""never"" showed the highest figure of 74.7%, while ""had"" showed the only 22.6% of total longevous people surveyed. 3. Of the details of disease and/or injury after 60 years of longevous people. ""digestive disease"" showed the highest figure of 32.6%. followed by ""apoplexia cerebri & hypertensions""(14.0%) and ""heart disease""(14.0%), and followed by ""respiratory disease""(12.3%). 4. Of the experiences of suffering between 40 and 60 years of longevous people, ""never"" showed 53.7% of total longevous people surveyed, while the frequency of suffering decreased in the order of ""once""(22.7%), ""2 times""(15.8%) and ""3 times""(4.7%). By the details of suffering between 40 and 60 years of longevous people. ""family life"" showed the highest figure of 85.1%, followed by ""business""(10.1%). 5. By the attitude on suffering of longevous people, ""tried to forget soon"" showed the highest figure of 54.2%, followed by ""continuous worried""(23.3%), and followed by ""not worried""(7.2%).

백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.

Antioxidant and cytoprotective effects of morin against hydrogen peroxide-induced oxidative stress are associated with the induction of Nrf-2-mediated HO-1 expression in V79-4 Chinese hamster lung fibroblasts

Lee, Moon Hee,Cha, Hee-Jae,Choi, Eun Ok,Han, Min Ho,Kim, Sung Ok,Kim, Gi-Young,Hong, Su Hyun,Park, Cheol,Moon, Sung-Kwon,Jeong, Soon-Jeong,Jeong, Moon-Jin,Kim, Wun-Jae,Choi, Yung Hyun Spandidos Publications 2017 International journal of molecular medicine Vol.39 No.3

<P>Natural phytochemicals of plant origin, including flavonoids, have been found to be potent antioxidants providing beneficial effects against oxidative stress-related diseases. The present study was carried out to investigate the antioxidant properties of morin, a flavonoid originally isolated from the flowering plants of the Moraceae family. Superoxide dismutase (SOD)-like activity and 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS(center dot+)) radical scavenging activity were determined. We also investigated the cytoprotective effects of morin against hydrogen peroxide (H2O2)-induced DNA damage and apoptosis in V79-4 Chinese hamster lung fibroblasts. Our results demonstrated that morin had strong scavenging effects against ABTS' radicals with enhanced SOD activity, which varied in a dose-dependent manner. Morin was found to reduce H2O2-induced intracellular reactive oxygen species generation and nuclear DNA damage, and it recovered cell viability damaged by H2O2 via inhibition of mitochondrial dysfunction-mediated apoptosis. Notably, the treatment of V79-4 cells with morin markedly enhanced the expression of heme oxygenase-1 (HO-1) but not quinone oxidoreductase-1, which was associated with the increased expression and phosphorylation of nuclear factor-erythroid 2-related factor 2 (Nrf2) and the downregulation of Kelch-like ECH-associated protein 1 expression. Based on our findings, we conclude that morin effectively ameliorated oxidative stress-induced DNA damage through intrinsic free radical scavenging activity and activation of the Nrf2/HO-1 pathway.</P>

8년간(1992~1999) 산업안전보건연구원에 의뢰된 직업병 심의 사례 분석

강성규,김규상,김양호,최정근,안연순,진영우,최병순,양정선,김은아,채창호,최용휴,김대성,박정선,정호근 대한산업의학회 2000 대한직업환경의학회지 Vol.12 No.2

Objectives : Pneumoconisis and noise-induced hearing loss (NIHL) have been reported as main occupational diseases by the Special Health Examination. The Industrial Accident Compensation Insurance has reported various work-related diseases, however, these two diseases occupied almost a half of compensated cases. Therefore, it was not well known about the status of occupational diseases other than pneumoconiosis, NIHL, and cardio-cerebrovascular accident (CVA). This study was conducted to analyze claimed cases as an occupational disease, that was requested to the Korea Industrial Safety and Health Agency (KOSHA). Methods : The local office of the Korea Labor Welfare Corporation (KLWC) has asked the KOSHA for confirmation of claimed cases as an occupational disease. We analyzed 379 cases requested from KLWC, the Ministry of Labor, employers, unions and occupational health agencies from 1992 to 1999. Results : Male was 80.7 % of the requested cases. Their mean age was 42 years old and 75.5 % of them were more than 35 years old. The requested cases were increased rapidly from 25 cases in 1992 to 108 cases in 1999 and the accept rate was 50.7 %. The majority of requested cases were respiratory diseases(22.4%), cancers(18.5%), Neuropsychiatric problems(14.5%), and musculoskeletal problems(13.5%). The accept rate was high in reproductive, respiratory, musculoskeletal and digestive disorders and low in neuropsychiatric, renal and otologic problems and occupational cancers. 73.6% of them were caused by chemical agents, especially 28.5 % were by organic solvents. 67% of them were clinically confirmed at university hospitals. A half of the cases were from KyongIn area, even the request came from the whole country. Conclusions : A claim was common in workers whose age was over 35 years old and exposure history was over 10 years. The respiratory diseases and neuropsychiatric disorders were still main problems in occupational health and occupational cancers was increasing even though its accept rate was not high yet.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

Goretex를 이용한 융비술

최진영,민철기,명훈,황순정,서병무,이종호,정필순,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

융비술시 실리콘 고무는 다루기 쉽고 조직 반응이 적어 현대 많이 돌출의 합병증이 생길 수 있다. 저자등은 이러한 실리콘의 단점을 보완할 수 있는 goretex를 사용하여 융비술을 시행하고 비첨에 대해서 자가연골을 이식하여 만족할 만한 결과를 얻었기에 goretex가 안면부 연조직의 증강을 위한 이식재료로 적합하다고 생각되어 문헌고찰과 함께 보고하는 바이다. Many different materials have been used to provide augmentation of the nasal dorsum. this include both autogenous and homogenous materials,as well as allografts. Silicone among the artificial materials has been most widely used. The silicone has some advantages and disadvantages. Goretex(expanded polytetra-fluoroethylene) which has widely used in vascular surgery and abdominal surgery can be used for facial soft tissue augmentation. The author presemts 2 cases of nasal augmentaion using goretex with literature review.

원발성과 이차성 기흉에서 비디오흉강경수술의 임상결과

최순호,류대웅,이미경,이삼윤 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

배경: 젊은 성인에서 자발성기흉의 치료는 논란이 많다. 흉관삽관술로 구성된 고식적인 치료는 흉관 삽관시기의 이환율, 장기간의 입원 그리고 일정기간 안에 수술을 요한다. 젊은 성인에서 기흉은 보통 폐 첨부의 기포를 동반한 것처럼, 저자는 첫 기흉의 발생 시기에 기포의 흉강경하 절제는 낮은 이환율과 짧은 입원 일을 동반하는 효과적인 치료이며 개흉술에 대한 훌륭한 대체수단이라고 가정하였다. 대상 및 방법:2005년 1월부터 2006년 12월까지 166명의 기흉환자에서 비디오흉강경수술을 시행하였다. 155명은 남자이었고 11명은 여자이었다. 평균 나이는 29.3±6.7세(15-75세)이었다. 환자는 특히 날씬하고 키가 컸으며 증상의 발현시기에 경도의 호흡곤란과 흉통을 보였다. 폐 첨부의 기포는 조직 검사로 확인을 하였다.130명의 환자는 5일이상의 지속적인 공기누출과 흉부 컴퓨터사진상 다발성 기포 때문에,15명은 반대편 기흉으로, 7명은 양측성 기흉, 그리고 5명은 흉관삽관술의 치료 후 재발한 경우로 수술을 받았다. 모든 환자에서 Endo-GIA stapler 에 의한 폐 쐐기절제수술과 탈크도포, 그리고 늑막찰과상이 수행되었다. 추적 동안에 환자의 재발 과 잔존 만성 흉통을 관찰하였다. 결과: 수술사망은 없었다. 수술 후 합병증은 1명에서 과도한 늑막찰과상에 기인한 출혈로 재수술,9명의 환자에서는 7일 이상의 지속적인 공기누출, 그리고 3명에서 재발을 보였다. 재발은 수술 후 1-3개월 동안에 발생하였다. 그리고 또한 16명에서 경도의 잔존 흉통을 호소하였지만 진통제는 필요하지 않았다. 입원 일은 원발성 기흉 환자에서는 5.2±2.4일 그리고 이차성 기흉환자는 7.5±3.2일 이었다. 결론: 늑막유착술을 동반한 폐 첨부의 쐐기절제수술은 낮은 이환율과 짧은 입원 일을 동반하고, 초기 흉관삽관술이나 개흉수술 같은 고식적인 수술에 대한 매력적인 대체수단이다. 흉강경수술은 자발성 기흉 환자를 위한 효과적으로 처음 시도하는 수술일 수 있다. 이 질환의 병태생리상 기흉 환자는 기흉의 재발 때문에 엄밀한 추적을 요한다. Background:The treatment of spontaneous pneumothorax in young adult has been controversial. Conventional treatment consisting of chest tube thoracostomy may be associated with morbidity at the time of tube insertion, prolonged hospitalization, and interval operation in many patients. As spontaneous pneumothorax in young adults is usually associated with apical blebs, we hypothesized that video-assisted thoracic surgery(VATS) resection of the blebs at the time the first pneumothorax may be effective treatment associated with low morbidity and short hospital stay, and also viable alternative to thoracotomy. Method & materials. From Jan.2005 to Dec.2006,a series of 165 patients with spontaneous pneumothorax were treated by video-assisted thoracic surgery, there were 135 men and 11 women. The mean age was 29.3±6.7 years old(range:15to 78 years).Patients were predominantly tall and thin and also mildly symptomatic at the time of presentation. Apical bullae was confirmed in the pathologic specimen.139 patients was treated for persistent air leak(>5days) and multiple blebs & bullae on Chest CT, 15 patients for contralateral pneumothorax. 7 patients for bilateral pneumothorax, and another 5 patients for recurrent pneumothotax after conservative treatment. Stalpling of blebs and bullae with Edo-GIA stapler and pleurodesis by Talc poudrage and pleural abrasion was performed in all cases. During follow-up patients were observed for recurrence and residual chronic chest pain. Results: There was no postoperative death. Postoperative complications were reoperation due to excessive pleural abrasion in one patient and continued air leaks more than 7 days in 9 patients, and recurrence in 3 patients.Recurrence were occurred during postoperative 1 to 2 months also mild chronic residual chest pain also noted in 16 patients, but no required analgesics. The hospital stay was mean 5.2±2.4 days in primary spontaneous pneumothorax and mean 7.5±3.2 days in secondary pneumothorax. Conclusions: VATS wedge resection of apical bullaes with pleurodesis is associated with low morbidity and short hospitalization, and provides an attractive alternative to the conventional treatment of initial tube thoracostomy and possible interval repeat thoracostomy or operations. VATS may be an effective first line treatment for spontaneous pneumothorax.Due to the pathophysiology of this disease, patients should be closely followed for the occurrence of the pneumothorax.

원격 퍼스컴회의 시스템의 다자간 접속을 위한 SAS 구현

崔承鎬,張晟柱,鄭順玉 東新大學校 工業技術硏究所 1997 工業技術硏究 Vol.3 No.-

In this paper, we suggest new MCU to implement multipoint connection in the SAS of remote PC conference systems. The MCU should observe recommendations of H.231 and H.234 of ITU-T. While mixing video data, the number of attendants in limiteded because it decodes bit stream and then encodes again, therefore, multicasting in the application layer should be implemented to solve the limited element. This program implemented the module that enables group manager of SAS and group server to procede and transmit multimedia data. The validity of paper was proved by implementing the function of image rotation that can display all of attentant in SAS of romote PC conference. The main service system is implemented based on Windows NT and Visual C^(++) 2.0.

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.