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Sohn, Seil,Chung, Chun Kee,Park, Sung-Hye,Kim, Eun-Sang,Kim, Ki-Jeong,Kim, Chi Heon M. Nijhoff ; Kluwer Academic Publishers 2013 Journal of neuro-oncology Vol.114 No.3
<P>The fate of residual spinal schwannomas needs to be estimated in order to plan further management after subtotal removal. Our aim was to evaluate the growth rate of residual spinal schwannomas and compare results in regrowth and no regrowth groups by using data collected from the Korea Spinal Oncology Research Group database. From January 1989 to August 2011, 27 patients with residual spinal schwannomas were selected. Patients with at least two follow-up magnetic resonance image (MRI) studies after subtotal resection were included. The mean period of MRI follow-up was 62.4 months. A tumor size increase of over 2 mm in the maximal diameter was considered indicative of regrowth. Age, sex, size at initial diagnosis, postoperative tumor size, and Ki-67 labeling index were compared between regrowth and no regrowth groups. Eight residual schwannomas regrew (29.6 %), and 19 (70.4 %) did not regrow. Average growth rate of the regrowing tumors was 1.0 4.4 mm/year. The mean percentage increase in tumor size during follow-up was 10.0 28.8 %. The Ki-67 labeling indices were significantly different between regrowth and no regrowth groups (P = 0.014). Two patients underwent a revision operation for significant tumor regrowth. Nineteen cases (70.4 %) among 27 residual spinal schwannomas did not regrow significantly, but further surgical treatments were necessary in 2 patients due to significant regrowth. The Ki-67 labeling index was higher in the regrowth group. Earlier follow-up MRI is recommended for patients whose tumors have higher Ki-67.</P>
요통(腰痛) 환자에 대한 침치료(針治療)와 직접구(直接灸) 병행치료(竝行治療)에 대한 비교(比較) 연구(硏究)
위종성,원승환,황정수,선승호,안영민,손승현,박기철,박희수,We, Jong-sung,Won, Seung-hwan,Hwang, Jung-soo,Sun, Seung-ho,Ahn, Young-min,Sohn, Seung-hyun,Park, Ki-chul,Park, Hee-soo 대한침구의학회 2004 대한침구의학회지 Vol.21 No.6
Objective : The purpose of this report is to examine the effects of direct moxibustion in the Low back pain patient. Methods : Clinical studies were done 30 patients who were treated with low back pain to Dept. of Acupuncture & Moxibustion, of Oriental Medical Sang-Ji University from September 1, 2003 to August 31, 2004. We treated them by Oriental medical therapy(including direct moxibustion)for 10 days. The evaluation was performed five times(admission day, before and after each twice). Results : 1. VAS was decreased after direct moxibustion for 10 days significantly(p<0.01). 2. After direct moxibustion, S.L.R. T angle of patients were increased. ConclUsions : We brought to the conclusion that direct moxibustion has possibility to the efficient to cure the Low back pain. So we suggest the possibility to use this treatment for Low back pain.
Focal adhesion kinase and src expression in premalignant and malignant skin lesions
( Ju Yeon Choi ),( Jae Yun Lim ),( Han Saem Kim ),( Jung Min ),( Jung In Kim ),( Hyun Min Seo ),( Sang Hyeon Hwang ),( Chong Won Choi ),( Yoon Hwan Kim ),( Jin Hee Sohn ),( Hyunjoo Lee ),( Won Serk Ki 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2
Background: Focal adhesion kinase (FAK) and Src are non-receptor tyrosine kinases. FAK and Src play a critical role in inducing malignant transformation in tumor cells. Objectives: We performed immunohistochemical staining for total and phosphorylated forms of FAK and Src, to evaluate the role of FAK and Src in the development of premalignant and malignant skin lesions. Methods: A total of 59 facial skin samples (30 actinic keratoses, 10 Bowen``s diseases, 13 squamous cell carcinomas and six perilesional skins) were immunohistochemically stained for Ki-67, total (t) and phosphorylated (p) form of FAK and Src. Methods: A total of 59 facial skin samples (30 actinic keratoses, 10 Bowen``s diseases, 13 squamous cell carcinomas and six perilesional skins) were immunohistochemically stained for Ki-67, total (t) and phosphorylated (p) form of FAK and Src. Results: Cells positive for t-Src, p-Src-y530, t-FAK and pFAK-s722 were detected in premalignant intra-epithelial lesions (PELs) and squamous cell carcinomas (SCCs), but not in the perilesional skin. There was a tendency towards high correlation between Ki-67 and t-FAK or pFAK-s722, suggestive of the active role of FAK in cell proliferation. Conclusion: Our findings of higher t-Src and p-Src-y530 positive cells in PELs, as compared to SCCs (with higher Ki-67 level), are suggestive of the other role of Src in tumor formation and progression, which requires further investigation.
현동우,박재용,강태경,박기수,박태인,김창호,손상균,권건영,이규보,정태훈,권삼,Hyun, Dong-Woo,Park, Jae-Yong,Kang, Tae-Kyung,Park, Ki-Soo,Park, Tae-In,Kim, Chang-Ho,Sohn, Sang-Kyun,Kwon, Kun-Young,Lee, Kyu-Bo,Jung, Tae-Hoon,Kweon, Sam 대한결핵및호흡기학회 1998 Tuberculosis and Respiratory Diseases Vol.45 No.1
저자들은 발열, 체중감소 등의 증상과 흉부 X-선 사진상 폐경화의 소견이 있었던 환자에서 폐의 병변이 역형성 거대세포 림프종으로 추측되는 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Anaplastic large cell lymphoma(ALCL) is a recently recognized large cell lymphoma characterized by large pleomorphic cells, with prominent nucleoli, expressing the CD30(Ki-1) antigen. It is often misdiagnosed as metastatic carcinoma, malignant histiocytosis or Hodgkin's disease. Primary pulmonary ALCL is extremely rare although it frequently involves extranodal sites, e.g. skin, bone, gastrointestinal tract, soft tissue and lung. We report a case of ALCL suspected as primarily involving lung.
Sang-Ho Lee,Ki-Seok Oh,Yong-Min Kim,이진아,Seong-Won Sohn,손창호 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.5
Cell-free fetal RNA is useful to determine fetal sex and detect other inherent genetic disorders. However,non-invasive fetal sex determination methods using fetal RNA from maternal plasma is not yet well established instudies pertaining to bovine animals. Thus, the aim of this study was to systematically evaluate the presence of themale-specific ZRSR2Y gene transcript in maternal plasma using Reverse Transcriptase-Polymerase Chain Reaction (RTPCR)assays, and to verify its accuracy, sensitivity, and specificity in determining fetal sex between 30 and 100 daysof gestation. Overall accuracy, sensitivity, and specificity of the ZRSR2Y gene transcripts in determining fetal sexwere 89.1%, 86.3%, and 100%, respectively. The 30 to 100 days of gestation were further classified into five stagesof gestation, and each stage had relatively high accurate, sensitive, and specific results. Overall, these results indicatethat the expression of the ZRSR2Y gene can be used for fetal sex determination in bovine animals using circulatingcell-free RNA in maternal plasma during early pregnancy
S-68 A Primary Hepatic Leiomyoma in a Gastric Cancer Patient
( Sung Ju Kang ),( Suk Hyun Jang ),( Hyung Bin Yuk ),( Jang Sihn Sohn ),( Ki Hyun Ryu ),( Sun Moon Kim ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1
An asymptomatic, 57-year-old man without any significant medical history was referred to our hospital because of early gastric cancer and a hepatic mass. Esophagogastroduodenoscopy revealed a superficial elevated lesion with central depression approximately 20 mm in size in the posterior wall of the antrum of the stomach. Pathologic examination confirmed well-differentiated adenocarcinoma. The laboratory tests and tumor markers, including AFP, CA19-9, and CEA, were within the normal range. Computed tomography (CT) revealed the hepatic mass was approximately 33 mm in size in segment Ⅱ/Ⅲ of the liver. However, the imaging cannot reliably differentiate between sclerosing hemangioma and metastasis. He underwent a US-guided needle biopsy, but we couldn't obtain a biopsy specimen, as the firmness of the liver mass made it impossible to put the needle through into the core. Subsequently underwent a diagnostic laparoscopic wedge resection. The mass was histologically typical for a leiomyoma. Primary hepatic leiomyoma (PHL) is a very rare benign tumor, with only 36 cases reported in the world literature. Surgical resection is both diagnostic and curative. This is the first report describing PHL in the domestic literature and the first report describing PHL diagnosed with coexisting gastric cancer in the world literature. In conclusion, when the patient presents a hepatic mass with another malignancy, reliable tissue diagnosis is necessary to exclude this rare entity, especially if the imaging cannot reliably differentiate between hemangioma and metastasis.
UPnP robot middle ware for dynamic services
Ki-Woong Lim,Sang Chul Ahn,Yong-Moo Kwon,Heedong Ko,Hyoung-Gon Kim,Kwanghoon Sohn 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
In the future, robots will be become more intelligent and complex. Accordingly, their services will becom-posed of S/W components. In that case, robots need to support various services for user by managing many internal components. Hence, it is important to reconfigure robot services and to manage components in ordertouse them ef-ficiently. The UPnP(Universal Plug and Play) is a middle ware that has many advantages for future robots in dynamic distributed computing environment such a subiquitous computing environment sad we have developed UPnP based robot middle ware. UPnP control point is automatically enabled to discover UPnP device using SSDP protocol. In this paper, we propose the Component Manager and UPnP Connect Service to enable dynamic service reconfigurations. We imple-mented a method that dynamically changes the search target to connect without pause of the robot using the Component Manager and UPnP Connect Service. Component Manager is also freelyable to load and unload component sin to the memory. And the paper shows that the proposed solution is useful and effective to manage robot components and recon-figure robot services by applying Connect Service to various robots.
Sohn, Young Bae,Kim, Su Jin,Park, Sung Won,Park, Hyung‐,Doo,Ki, Chang‐,Seok,Kim, Chi Hwa,Huh, Seung Won,Yeau, Sunghee,Paik, Kyung‐,Hoon,Jin, Dong‐,Kyu Wiley Subscription Services, Inc., A Wiley Company 2010 AMERICAN JOURNAL OF MEDICAL GENETICS PART A Vol.a152 No.12
<P><B>Abstract</B></P><P>Mucopolysaccharidosis type II (Hunter syndrome) is a lysosomal storage disease caused by a deficiency of iduronate‐2‐sulfatase. Most reported patients are males because of X‐linked recessive inheritance pattern. Only a few female patients with Hunter syndrome have been reported, and there is no prior report of offspring from a patient with Hunter syndrome. In this report, we describe a woman with mild manifestations of Hunter syndrome who gave birth to a daughter. Both the mother and daughter carried the p.R443X mutation in exon 9 of the <I>ID2S</I> gene. Iduronate‐2‐sulfatase activity in the mother was as low as that found in male Hunter syndrome patients, but it was in the low‐normal range in her daughter. Unlike her mother, the daughter did not show any physical signs of Hunter syndrome, and urinary excretion of glycosaminoglycan was within normal range. However, she had severe pulmonary vein stenosis with pulmonary hypertension and a large atrial septal defect and died at 11 months of age. © 2010 Wiley‐Liss, Inc.</P>