Pseudomonas sp. YS-542가 생산하는 Chitinase의 정제

강신욱,최희상 慶北專門大學 2003 慶北專門大學 論文集 Vol.22 No.-

The optimal condition for the production of chitinase from Pseudomonas sp. YS-542 was follow ; 1.0% colloidal chitin, 1.0% tryptone, 0.2% MgSO_(4)7H_(2)O, 0.1% K_(2)HPO_(4), pH 8.0 at 25℃ for 48hrs cultivation. The chitinase was purified by ammonium sulfate fractionation, two times of affinity adsorption. Yield of the purified enzyme was 19.2%. The purified enzyme showed a single protein band on polyacrylamide gel electrophoresis and its molecular weight was estimated to be 47,000 by SDS-polyacrylamide gel electrophoresis.

동종골수이식 환자에서 발생한 지역사회발생 Parainfluenza virus 3형 폐렴 1예

신종욱,조요한,강철인,김성한,이상윤,김의석,오명돈,이환종,박선양,김병국,최강원 대한감염학회 2002 감염 Vol.34 No.5

시동전동기의 기동소음 평가기법에 관한 실험적 연구

신영재,강성황 安東大學 1994 安東大學 論文集 Vol.16 No.1

Noise and its effect on quality has recently become an important issue in the area of the starting motor cranking sound. This study has determined the algorithm of cranking sound evaluation for starting motor. Traditional noise analysis techniques did notcoonsistently correlate with subjective jury rating of the cranking sound. As a result, an algorithm based on time domain microphone output was developed to correlate objective measurements of cranking sound to subjective jury ratings. The algorithm contains three parameters to describe the cranking sound, and good correlation between the two ratings has been observed. When jury test results has been inconclusive, the algorithm has proven helpful in evaluating incremental design changes to current starting motor specification.

중독한 추체로 증상을 보인 cyclosporine에 의한 뇌증 1예

강정현,곽승근,신현영,김성은,이정호,이정찬,곽상혁,윤환중,조덕연,김삼용,김제,송창준 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

The use of cyclosporine(CsA), a potent immunosuppressive agent, is associated with numerous side effects. Neurotoxicity was earlier less well known, but with growing experience central nervous system side effects are now reported up to 40% of patients. Among various CsA-induced neurotoxicities, tremor is most common and posterior leukoencephalopathy is well characterized. An encephalopathy presenting with pyramidal weakness, however, seems to be rare and poorly documented. We report here a case of encephalopathy presenting with multiple generalized seizures followed by fluctuating quadriparesis developed a few days after starting CsA and resolved spontaneously after withdrawal of the drug . A 48-year-old woman with aplastic anemia was placed upon immmunosuppressive treatment consisting of antithymocyte globulin(ATG), CsA, and methylprednisolone. Two days after starting the therapy, she developed a generalized seizure. The next day she developed 2 more episodes of seizure and the therapy was stopped. Computed tomogram of the brain was normal. Six days after starting therapy, she developed mild motor weakness and paresthesia of both lower extremities, which progressed to a definite quariparesis confining her to a bed in 3 days. Magnetic resonance imaging(MRI) of the brain revealed asymmetric, bilateral high-signal abnormalites in the subcortical white matter of fronto-temporal areas. After reaching to a maximum with some fluactuation(14 days after starting the therapy) the motor weakness started to be resolved. She was discharged with a almost complete resolution of the weakness 45 days after starting the therapy. Five months later she did well and brain MRI was negative.

Landscape Ecological Study on the Habitats of Genus Ranunculus Plants and its Distribution

Kang,Shin-Ho,Ko,Sung-Chul 한국자원식물학회 2002 Plant Resources Vol.5 No.1

The purposes of this study were to clarify of floristic composition and the landscape structure on the habitats of each Ranunculus plant, which were distributed in Daejeon, Korea. Three taxa were distributed and investigated in this study. Floristic composition of habitats were organized by living in flatten open space needed a lot of sunlight and humidity species. Landscape ecological structure of habitats were defined by soils of coarse loamy and loamy skeletal, slope of under 15$^{\circ}$ 수식 이미지, under the (five percent of woody coverage at 100-300m above the sea levels. Distribution patterns of Ranunculus plants in Daejeon were presented on the 1km X 1km grid map.

관해유도 화학요법을 받는 급성 백혈병 환자에서 발생한 감염증에서 Imipenem 단독요법과 Ceftizoxime + Amikacin 병용요법의 효과 및 안전성에 관한 전향적 비교 연구

신형식,김성민,이기형,최희정,김남중,오명돈,박선량,김병국,최강원 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.2

A total of 40 febrile granulocytopenic patients with acute leukemia were randomized to receive imipenem-cilastatin or ceftizoxime plus amikacin as initial empirical therapy to compare the efficacy and safety of imipenem monotherapy with that of ceftizoxime/amikacin combination therapy. 21 patients were randomized to the imipenem monotherapy, while 19 patients to the ceftizoxime/amikacin combination therapy. On 72 hour assessment success rates accordings to NCI criteria were 100% in both groups, success rates according to IHS (Immunocompremised Host Society) criteria were 55.0% in imipenem group and 66.7% in ceftizoxime/amikacin group. On overall assessment success rates according to NCI criteria were 90.0% in imipenem group and 94.7% in combination group, success rates according to IHS criteria were 50% in both groups. There was no statistical difference in success rate between two groups. Hepatotoxicity was the most common side effect in both groups(imipenem 15.0% vs. ceftizoxime/amikacin 15.8%). There was no CNS tixicity in both groups. Nausea and vomiting occurred in 9.5% of imipenem recipients, and 1 patients was unable to complete therapy due to intolerance. In summary, imipemem monotherapy was effective and safe empirical antibiotic therapy as compared with ceftizoxime/amikacin combination therapy.

날씨가 주가에 미치는 영향

신민식,강성미 慶北大學校出版部 2004 經商論集 Vol.32 No.1

Based on psychological evidences, which show that weather affects mood, and this could also affect decision-making, we analyzed correlations between cloud cover and the daily composite index within Seoul, Daejeon, Daegu, Gwangju, Busan which are representative cities from Korea. Evidence demonstrates the following. First, analysis supports the correlation between cloud cover data and the daily composite index and shows that cloud cover affects stock returns negatively except for those in Daejeon. Second, we study the correlation between cloud cover of days when it has no rain and the daily composite index shows that Gwangju is not positive anymore. It has reverse effects particularly for Daejoen, as the data indicates opposite results. Third, the correlation between new cloud cover figures are weighted with GRDP data and the daily composite index show that cloud cover is significantly correlated with negative stock returns.

유기박막 광도파로형 바이오(칼슘이온)센서의 개발

강신원,박이순,김성훈,김창원 경북대학교 센서기술연구소 1955 연차보고서 Vol.1995 No.-

본 연구는 고감도, 빠른 응답특성 및 넓은 센싱범위를 갖는 능동형 유기박막 광도파로형 칼슘이온센서를 개발하였으며, 이와 병행하여 중성 ionophore와 함께 특정 음이온 선택성의 색소(LAD : lipophilic anionic dye)를 설계·합성을 하였다. 유기박막 광도파로형 칼슘이온센서는 감지막 자체를 박막광도파로화 함으로써 빠른 응답시간과 고감도의 특성을 가졌으며, 514㎚ 광원에서 10^-6∼1M의 범위의 Ca^++ 의 농도를 측정할 수 있었다. 또한 새로이 합성된 LAD의 칼륨이온선택성을 분광측정으로 평가한 결과, 광이온센서(optode)들의 변색성 이온감응물질로서 사용이 가능함을 확인하였다. A new approach to the design and construction of thin-film optical waveguide Ca^+2 sensor has been developed by using a copolymer matrixed membrane that incorporates a cation-selective neutral ionophore, H^+-selective neutral chromo-ionophore, and lipophilic anionic sites in the same plasticized copolymer membrane. This sensor is based on absorption measurement, and it makes use of host molecules that change their optical properties through an actual ion-sensitivity recognition process. In parallel, the high ion-selective lipophilic anionic dye(LAD) was synthesized and evaluated. Proposed ion sensor, utilizing thin film membrane which is the waveguide itself, exhibited rapid response time and high sensitivity. And sensor could detect a wide range of Ca^++ concentrations ranging from 10^6 ∼ 1M by measuring the absorbance change at 514㎚ of light. The newly synthesized LAD showed its potential applicability as chromoionophore for optodes and/or thin-film optical waveguide sensors.

14각형 헥사아자 거대고리 구리(II)착물과 음이온의 반응에 미치는 리간드의 치환기 효과

姜信杰,李成得성득,權在槿,鄭守炅 大邱大學校附設 基礎科學硏究所 1991 基礎科學硏究 Vol.8 No.-

Reactions of copper(In complexes of 1, 8-dimethyl-, 1, 8-diethyl-, and 1, 8-dipropyl-1, 3, 6, 8, 11, 13-hexaazacyclotertradecanes(A, B, and C, respectively) with halide and pseudohalide ions have been studied in aqueous solutions by spectrophotometric method. It is observed that the equilibrium constants(K) of these reactions decrease with the ligand structure in the order A> B>C for anions and decrase with the anions in the order SCN^(-)>N_(3)^(-)>Br^(-)>Cl^(-) for complexes. The values of K increased with increasing temperature. Thermodynamic parameters obtained from the equilibrium constants are investigated.

알루미늄 압출부재의 굽힘붕괴 해석 및 실험에 관한 연구

강신유,서성수 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-

This study is concerned with characteristics of bending collapse of aluminum members with multi-cell section. Aluminum is light so it is compatible of being used for vehicle structures members. Bending collapse behaviors of aluminum members with multi-cell section are very complex and tension failure mode are occured in experiment. In this paper, the aluminum members are modeled to be able to represent the tension failure mode and, characteristics of bending collapse of aluminum members with multi-cell section by experimental method are compared with the results of PAM-CRASH.