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      • SCISCIESCOPUS

        Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

        Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

        <B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

      • 대장선암에서 p53과 c-erbB-2의 표출 및 상관관계에 관한 연구

        양승하,강상균,김대중,김의한,김만성 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

        Colorectal adenocarcinoma is relatively common malignant tumor in korea and various oncogenes has found in tumor cells. Colorectal adenocarcinoma show overexpression of p53 and c-erbB-2. The relation between expression of p53 and c-erbB-2 and prognosis of patients in colorectal adenocarcinoma has studied recently, but that is controversy. To evaluate relation between expression of p53 and c-erbB-2 and histopathologic finding prognostic factors, we have performed immunohistochemical staining, using mouse anti-p53 and anti-human c-erbB-2, for 52 cases of colorectal adenocarcinoma. The results were as follows; 1) Expression rate of p53 and c-erbB-2 in colorectal adenocarcinoma were 71.2% and 51.9%, respectively. 2) Expression rate of p53 in left side(70.4%), differentiated(75.6%) and invasion to serosa and surrounding adipose tissue(72.5%) were higher than in right side(37.5%), poorly differnetiated(42.9%) and invasion to muscle(50%). 3) Expression rate of c-erbB-2 in left side(51.9%), differentiated(57.8%) and invasion to serosa and surrounding adipose tissue(54.5%) were higher than in right side(37.5%), poorly differnetiated(14.3%) and invasion to muscle(37.5%). 4) The expression of p53 and c-erbB-2 showed coexpression in colorectal adenocarcinoma. 5) The expression of p53 and c-erbB-2 showed no differenece according to presence or absence of lymphatic metastasis. Above result revealed that p53 and c-erbB-2 are coexpression in colorectal adenocarcinoma. The expression of each p53 and c-erbB-2 and the simultaneous expression of p53 and c-erbB-2 may be related to left side and differentiated cases. Our studies for relation with prognosis of patients in colorectal adenocarcinoma showed different results according to depth of invation and metastasis to lymph node and we should be followed for them.

      • SCOPUSKCI등재

        3차원 광밴드갭 결정 : 제조와 응용 Fabrication and Applications

        양승만,이기라 한국화학공학회 2003 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.41 No.3

        미시적 공간에서 광자르 자유롭게 제어할 수 있는 소재인 광결정은 광통신과 광컴퓨터에 쓰이는 채널드롭 필터(channel drop filter), 광파가이드(optical waveguide), 나노레이저(nanolaser)와 같은 핵심소자의 기본 재료일 뿐만 아니라 차세대 마이크로디스플레이의 칼라화소로 활용될 수 있다. 본 글에서는 3차원 광결정의 기본 개념과 지금까지 제안된 제조공정을 소개하고 응용분야에 대해 살펴본다. 광결정 제조 공정 중 화학공학자들의 관심을 끌 수 있는 콜로이드 자기조합체(self-assembly)의 3차원 광결정으로의 응용에 대해 중점적으로 소개하고자 한다. Photonic crystals are referred to as semiconductors for light and can control the flow of photons in microscopic space since semiconductors do the flow of electrons in ULSI(Ulta Large Scale Integration) circuits. Therefore, photonic crystals have attracted enormous attention due to their potential applications including channel-drop filters, nanolasers, optical waveguides and others that are required for the development of next-generation optical telecommucation devices and optical computers. Photonic crystal balls at micrometer scales can be also used as full-color pixel sources in fabrication of three-dimensional photonic crystals have attracted enormous attention due to their potential applications including channel-drop filters, nanolasers, optical waveguides and others that are required for the development of next-generation optical telecommunication devices and optical computers. Photonic crystal balls at micrometer scales can be also used as full-color pixel sources in the pioneering microdissional photonic crystals, and their potential application areas. In particular, we emphasize the colloidal self-assembly scheme that is the most attractive to chemical engineers among several synthetic methods.

      • 위선암에서 조직면역학적 방법을 이용한 P-glycoprotein의 분포에 관한 연구

        김만성,양승하,김의한,강상균 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

        P-glycoprotein, as a pleotropic membrane transport protein, shows specific localization in many normal tissue and malignant tumor. It act as an energy dependent drug pump in malignant tumors and makes difficulty for treating these tumors with anticancer drugs. Many malignant tumors such as colon carcinoma, renal cell carcinoma, hepatoma, islet cell tumor of pancreas, and adrenal cortical carcinoma, show high expression of P-glycoprotein and resistance to chemotherapy. However reports for P-glycoprotein in gastric adenocarcinoma is rare. The difference of its expression according to differentiation of gastric adenocarcinoma has been studied and its results are controversial. To observe the relationship of P-glycoprotein positivity according to differentiation of carcinoma, age and sex, adenocarcinoma 82 cases and dysplastic lesions 12 cases were analysed then processed for immunohistochemical stain by avidin-biotin complex using mAB JSB-1. The results were as followings : 1. Positive rate of P-glycoprotein in gastric adenocarcinoma and dysplastic lesions were 48.78%(40/82) and 50%(6/12). 2. Well, moderate and poorly differentiated adenocarcinoma showed positive reaction of P-glycoprotein in 51.28%(20/39), 46.43%(13/28) and 46.67%(7/15) respectively. 3. Positive reaction of P-glycoprotein in male was 53.85%(35/65) and female in 29.41%(5/7) which indicate high positive rate in male. 4. Positive rate of P-glycoprotein according to age distribution were 25%(1/4) in 20-30 decade, 42.8%(6/14) in 40 decade, 44.83%(13/29) in 50 decade, 57.14(12/21) in 60 decade and 57.14%(8/14) in 70 decade. It indicate that P-glycoprotein positivity is increased with age. The above results reveal that the expression of p-glycoprotein in gastric adenocarcinoma as related with sex and age but not with differentiation of carcinoma. These results implies that P-glycoprotein may be implicated with hormone dependent.

      • 산성강하물의 침착량과 동태 해명에 관한 연구 -춘천과 서울 강우의 화학조성 비교 : Comparison of Chemical Composition of Rain Water between Chunchon and Seoul

        김만구,강미희,임양석,박기준,황훈,이보경,홍승희,이동수 江原大學校 附設 環境硏究所 1999 環境硏究 Vol.16 No.-

        The rain water samples were collected at Chunchon and Seoul by using wet only automatic sampler from January 1996 through December 1997. The daily base rain water samples collected over than 95% rainy events during the whole period. The samples were measured both pH and conductivity, and were analysed major ionic components, SO₄^(2-), NO₃^(-), Cl^(-), NH₄^(+), Ca^(2+), Na^(+) and K ^(+), by ion chromatography. In 1996, about 77% sampled rain water showed below pH 5.6 and the 60% of rain water was lower than pH 5.0. The volume weighted average pH was 4.7 at all sites. In 1997, the volume weighted average pH was 4.6 and 4.9 at Seoul and Chunchon, respectively. Among the rain water samples, 87% and 55% of samples showed below than pH 5.6 and 5.0, respectively. The pH value of Chunchon was significantly (p<0.05) lower than Seoul at the rain samples for less than 20 ㎜ rainfall. However conductivity of the rain samples were 20.9 μS/㎝ for 1996 and 27.7 μS/㎝ for 1997 at Seoul, and 19.1 μS/㎝ for 1996 and 14.1 μS/㎝ for 1997 at Chunchon. H₂SO₄AND HNO₃CONTRIBUTED 65.9% and 29.6% of free acidity at Seoul, respectively. The ratio of [NO₃^(-)]/[nss-SO₄^(2-)] were 0.43 at Seoul and 0.51 at Chunchon for rain samples for less than 20 ㎜ rainfall. The annual wet deposition of Cl^(-), NO₃^(-), SO₄^(2-), H^(+), Na^(+), NH₄^(+), K ^(+), Mg^(2+) and Ca^(2+), respectively, 568.8 ㎏/㎢, 1489.3 ㎏/㎢, 3184.8 ㎏/㎢, 20.9 ㎏/㎢, 249.4 ㎏/㎢, 1091.2 ㎏/㎢, 189.8 ㎏/㎢, 90.2 ㎏/㎢, and 702.4 ㎏/㎢ at Seoul for 1996; 656.4 ㎏/㎢, 2029.7 ㎏/㎢, 3280.7 ㎏/㎢,27.2 ㎏/㎢, 229.4 ㎏/㎢, 1063.9 ㎏/㎢, 106.9 ㎏/㎢, 7802 ㎏/㎢, and 645.3 ㎏/㎢, at Seoul for 1997; 116.9 ㎏/㎢, 983.3 ㎏/㎢, 1797.0 ㎏/㎢, 21.4 ㎏/㎢, 83.2 ㎏/㎢, 648.1 ㎏/㎢, 78.0 ㎏/㎢, 22.2 ㎏/㎢ and 368.8 ㎏/㎢ at Chunchon for 1996; 100.2 ㎏/㎢, 1077.6 ㎏/㎢, 1754.0 ㎏/㎢, 13.4 ㎏/㎢, 146.0 ㎏/㎢, 602.3 ㎏/㎢, 88.8 ㎏/㎢, 16.2 ㎏/㎢ and 206.8 ㎏/㎢ at Chunchon for 1997.

      • KCI등재

        교사의 근무학교에 따른 직업윤리, 조직몰입 및 조직효과성과의 인과관계

        문승태,양복만 한국농업교육학회 2007 농업교육과 인적자원개발 Vol.39 No.4

        본 연구의 목적은 교사들의 직업윤리와 조직몰입이 학교조직 효과성에 어떠한 영향을 미치는지를 살펴봄으로써 이들 변인과의 관련성을 명료화하는데 있으며,이를 위하여 먼저 선행연구 고찰을 통해 직업윤리,조직 몰입,학교조직 효과성 개념을 정립하였다. 초,중,고,특수학교 교사를 대상으로 설문 조 사를 실시하여 신뢰도와 타당도를 검증하였다. 그 주요 결과는 다음과 같다. 첫째,교사들의 근무학교에 따라 직업윤리의 하위요인인 자기관리요인,사회윤리,직무수행윤리,교권 윤리,학생지도윤리,조직 몰입,학교조직 효과성은 차이가 있는 것으로 나타났다. 전체적으로 초등학교 및 특수학교에 근무하는 교사들의 직업윤리,조직 몰입,학교조직 효과성이 높은 것으로 나타났다. 둘째,교사의 직무수행윤리,학생지도윤리,사회윤리는 조직 몰입을 29% 정도 설명하고 있었으며,직무수행윤리,사회윤리,직무수행윤리,교권윤리,학생지도윤리,조직 몰입은 학교조직 효과성의 63%를 설명하는 것으로 나타났다. 셋째,교사들의 직업윤리의 하위요인과 조직 몰입 및 학교조직 효과성과의 경로분석 결과,직업윤리 하위요인과 조직 몰입 및 학교조직 효과성 간에는 서로 관련성이 있음을 알 수 있다. 조직 몰입에는 사회윤리 .09,직무수행윤리 .34,학생지도윤리 .19가 직접적인 효과를 미치는 것으로 나타났으며,학교조직 효과에는 조직 몰입 .44,자기관리윤리 .22,교권윤리 -.13으로 직접적인 효과를 미치는 것으로 나타났다. 즉 학교조직 효과성에는 직업윤리와 조직 몰입이 직·간접인 영향을 미치고 있음을 알 수 있었다. The purpose of this study is to clarify the correlation among the factors by investigating the effects of teachers'vocation ethics and organization commitment on the school organization effectiveness. Some preceding studies have been made to establish the concepts of vocation ethics, organization commitment, and school organization effectiveness. A survey conducted on the teachers in the elementary, middle, high, and special schools proved this study reliable and reasonable. The major findings of this study are as follows: First, every school made some differences in such vocational sub-factors as self-control, social ethics, job performance ethics, teaching ethics, student guidance ethics, organization commitment, and school organization effectiveness. This study showed the teachers working in the elementary and special schools had a high level of vocation ethics, organization commitment, and school organization effectiveness. Second, the ethics related to job performance, student guidance, and society accounted for 29% of organization commitment, while the ethics related to job performance, student guidance, society, and organization commitment explained 63% of the school organization effectiveness. Third, the analysis of the sub-factors of teachers' vocation ethics, organization commitment, and school organization effectiveness has shown that they were correlated one another, Organization commitment is influenced directly by social ethics(.09), job performance ethics(.34), and students guidance ethics(.19), while school organization effectiveness is influenced directly by organization commitment(.44), self control ethics(.22), and teaching ethics(-.13). It means that vocation ethics and organization commitment have direct and indirect effects on school organization effectiveness.

      • KCI등재후보

        3구간 종속 가변속도하에서 배송차량의 최적운영 방안에 관한 연구

        문기주,양승만 대한설비관리학회 2004 대한설비관리학회지 Vol.9 No.2

        The vehicle routing problem with time-varying speed(VRPTVS) is difficult to handle with regular Traveling Salesman Problem(TSP) approaches due to the varying speeds. A 3 service zone partitioning method is developed in this research to adapt the government supplied traffic information as well as possible computing time reductions. The vehicle speed in each of the 3 splitted service zones based on the time window becomes fixed vehicle speed. A regular TSP algorithm for not coning back to the origin is applied for the delivery points in each zone and then 3 routes are connected for one initial completed vehicle route. A pairwise exchange method is applied to reduce the traveling time.

      • KCI등재

        동일한 시료에 대한 국내 기관간의 STR 분석결과 비교 : STR 유전자좌 분석법의 표준화 설정을 위하여

        박종태,신경진,양윤석,우광만,이숭덕,이승환,이정빈,정연보,조승희,한길로,한면수,홍승범 大韓法醫學會 2001 대한법의학회지 Vol.25 No.1

        This paper described a collaborative exercise intended to see what kinds of short tandem repeat (STR) loci are used in different DNA typing laboratories in Korea and to compare their results for the demonstration whether uniformity of DNA profiling results from different laboratory could be achieved in Korea Laboratories were asked to test five tissue DNAs using methods routinely used in each laboratory and to report the results to the coordinating laboratory. The exercise demonstrated that each laboratory was using different STR loci for the typing with different STR numbers,2 VNTRS,36 STRs and amelogenin in total, and the direct comparison of the results from all the laboratory for the 18 loci could not be done as only one laboratory submitted typing results. Among 21 loci for which several laboratories submitted typing results, results for 14 loci were the same and results for the other 7 loci were different depending on the participating laboratory. D1S80, F13A01, D16S539, D21S11, D18S51, D3S1744 were the loci with different typing results. Even in the cases where commercial kits were used, the results were not the same depending on the machines used, that is the capillary electrophoresis or the gel based electrophoresis. The reason for the different results, points about the standardization of the methods arid the profiling data were described.

      • SCIESCOPUSKCI등재

        Case Report : Hepatoid Carcinoma of the Pancreas Combined with Neuroendocrine Carcinoma

        ( Ji Ye Jung ),( Yoon Jae Kim ),( Hee Man Kim ),( Hong Jeoung Kim ),( Seung Woo Park ),( Si Young Song ),( Jae Bock Chung ),( Chang Moo Kang ),( Joo Yeon Pyo ),( Woo Ick Yang ),( Seung Min Bang ) The Editorial Office of Gut and Liver 2010 Gut and Liver Vol.4 No.1

        Hepatoid carcinoma is a primary extrahepatic carcinoma whose morphology, immunohistochemistry, and behavior are similar to those of hepatocellular carcinoma. The most common sites of extrahepatic carcinoma are the stomach and ovary, but nine cases of hepatocellular differentiation of the pancreas have been reported in the literature. We report another case of hepatoid carcinoma of the pancreas that was associated with the development of a pancreatic endocrine carcinoma in a 46-year-old man. Serum alpha-fetoprotein (AFP) was elevated to 262.49 IU/mL and radiological examinations revealed a mass measuring 7.5 cm in diameter in the head of the pancreas. He underwent a conventional Whipple operation, and light microscopy showed adenocarcinoma that was immunopositive for AFP, hepatocyte antigen, cytokeratin, chromogranin, synaptophysin, and alpha-1 antichymotrypsin. Although hepatoid differentiation was not shown unequivocally histologically, other immunohistochemistry findings supported the diagnosis of hepatoid carcinoma combined with neuroendocrine carcinoma. The patient was healthy and had no evidence of recurrence at 4 months after the surgery. This report describes why hepatoid carcinoma should be considered as a differential diagnosis of a pancreatic mass, especially when serum AFP is elevated. (Gut Liver 2010;4:98-102)

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