Dissolved Air Flotation(DAF) 접촉조의 수리동력학적 조건이 입자의 제거에 미치는 영향

유제선,김성훈,신은허,박희경 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

Hydrodynamic conditions for optimum solids capture within the contact zone, which are governed by the geometry and flow, are not yet well understood. In this research, dimensionless parameters which represent hydrodynamic conditions in the contact zone were derived, using the Buckingham π theorem. Those parameters are Reynolds No. (Re), Froude No. (Fr), Weber No. (We), Local Weber No., and Bubble Capacity No. (Bc). The particle removal rate was investigated by changing each value of the dimensionless parameters. The experimental results indicate that particle removal rate, when gravity dominates and the flow is semi-turbulent (Fr < 0.3, Re < 8000), is higher than when inertia dominates and flow is turbulent. For the We, higher removal rates were obtained in the range of the We < 40. Relative to the Local We, smaller bubbles which are influenced more by surface tension than inertia, demonstrated a higher particle removal rate than larger bubbles. For the Bc, the optimal range is from 0.3 to 0.5. We suggest that these dimensionless parameters can be used to diagnose the performance of and to design a DAF reactor.

전산유체 기법을 이용한 DAF 부상조에서의 수리 특성 고찰

김성훈,유제선,김영미,박희경 대한상하수도학회 2002 상하수도학회지 Vol.16 No.4

Dissolved air flotation is a solid-liquid separation process that uses fine rising bubbles to remove particles in water. DAF is found most effective in treating algae and lower density flocs that are hard to remove in sedimentation process. Some researcher reports the results of an experimental study which examined the flow within the flotation zone of a DAF tank (ONeill at al., 1997). I would be concluded that, in general, the flow within flotation zone is robust and that differences in the performance of individual DAF tanks must be the result of processes occurring within the contact zones of these tank, not as the result of flotation processes. In this research, the authors thought that the efficiency of the DAF process is strongly related to bubble size. It means bubble rising velocity at the air injection nozzle is most important factor of DAF process. However, bubble movement in DAF tank is somewhat complicate, so it is hard to make up conceptual model through simple mass balance as other researchers did (Leppinen at. al., 2000). For the modeling of turbulent 2-phase flow in the tank, the standard k-ε model was used in CFD code because it is widely accepted and the coefficients for the model are well established. This model uses the eddy-viscosity hypothesis for the turbulence. As the result of this study, the authors concluded that bubble size and its rising velocity is very important factor of DAF process and the recycle ratio must be also consider for the flotation zone parameter. Also, For the improved model, relation between turbulent intensity and bubble-particle attachment must be studied.

전산유체 기법을 이용한 용존공기부상법에서의 접촉도 조건변화에 따른 충돌효율평가

김성훈,유제선,박희경 대한상하수도학회 2004 상하수도학회지 Vol.18 No.2

Dissolved air flotation (DAF) is a solid-liquid separation process that uses fine rising bubbles to remove particles in water. Most of particle-bubble collision occurs in the DAF contact zone. This initial contact considered by the researchers to play a important role for DAF performance. It is hard to make up conceptual model through simple mass balance for estimating collision efficiency in the contact zone because coupled behavior of the solid-liquid-gas phase in DAF system is 90 complicate. In this study, 2-phase(gas-liquid) flow equations for the conservation of mass, momentum and turbulence quantities were solved using an Eulerian-Eulerian approach based on the assumption that very small particle is applied in the DAF system. For the modeling of turbulent 2-phase flow in the reactor, the standard k-ε mode Ⅰ(liquid phase) and zero-equation(gas phase) were used in CFD code because it is widely accepted and the coefficients for the model are well established. Particle-bubble collision efficiency was calculated using predicted turbulent energy dissipation rate and gas volume fraction. As the result of this study, the authors concluded that bubble size and recycle ratio play important role for flow pattern change in the reactor. Predicted collision efficiency using CFD showed good agreement with measured removal efficiency in the contact zone. Also, simulation results indicated that collision efficiency at 15% recycle ratio is higher than that of 10% and showed increasing tendency of the collision efficiency according to the decrease of the bubble size.

Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

정신분열병 환자를 위한 인지재활훈련 프로그램의 개발 : Korean-Cognitive Differentiation Program 한국형 인지분화훈련 프로그램

현명호,안석균,이만홍,조현상,최충식,이연희,송선미,유계준,김장우,김태용,이희상 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.2

연구배경 : 정신분열병 환자들은 인지장애를 보이는바, 저자들은 이들을 대상으로 한국형 인지분화훈련 프로그램을 개발하여 정신분열병 환자들을 대상으로 인지재활훈련을 실시한 후 환자들의 인지기능, 정신병리 및 문제해결기술에 미치는 효과를 조사하였다. 방 법 : 28명의 정신분열병 환자를 훈련군(n=14)과 대조군(n=14)으로 나누어 훈련군에게 한국형 인지분화훈련 프로그램을 1회 60분씩, 주당 2회씩, 11주간 총 22회를 실시하였다. 환자들의 인지기능은 K-WAIS의 산수, 빠진곳찾기, 어휘, 공통점찾기 소검사로 측정하였고 정신병리는 양성 및 음성증상 척도로 측정하였으며 문제해결기술은 사회문제해결척도로 평가하였다. 인지재활훈련의 효과를 평가하기 위해 훈련 전후의 인지기능, 정신병리 및 문제해결기술의 변화를 종속변수로 하고 훈련 유무를 독립변수로 하여 반복측정에 의한 변량분석으로 자료를 분석하였다. 결 과 : 한국형 인지분화훈련이 시간에 따른 인지기능검사 중 산수 소검사, 문제해결기술 중 시회문제해결척도의 전체 점수와 문제해결기술 소척도의 점수의 변화에 유의한 영향을 미쳤으나, 시각적 주의력, 개념화 능력 및 정신병리의 점수의 변화에 유의한 영향을 미치지 않았다. 결 론 : 한국형 인지분화훈련 프로그램은 정신분열병 환자에서 청각적 주의력 및 문제해결기술의 호전을 꾀할 가능성이 있음을 시사한다. Objectives : The purpose of this study was to investigate the effects of cognitive differentiation training program- Korean version(a training program of attention and conceptual abilities) on cognitive function, psychopathology and problem solving skills in patients with schizophrenia. Methods : A total of patients diagnosed as schizophrenia using DSM-Ⅳ were randomly assigned to 2 groups. The training group went through a total of 22 sessions of cognitive differentiation training(60 min/ session×2 sessions/wk×11 wks). The attention-placebo control group received psychoeducation program during the same period. Arithmetic, vocabulary, similarities, picture completion of Wechsler Adult Intelligence Scale-Korean version, Positive and Negative Syndrome Scale, and Social Problem Solving Scales were administered to all patients, both before and after the training program. Results : In the arithmetic scores(F=6.35, af=1, p=0.018) of Wechsler Adult Intelligence Scale-Korean version, and total scores(F=6.35, af=1, p=0.018) and problem solving skill scale scores(F=4.88, af=1, p=0.036) of social problem solving scale, interaction effects of training was significant. Conclusion : Our findings suggest that cognitive differentiation training program-Korean version is effective on improving auditory attention and problem solving skills in patients with schizophrenia.

Enhancement of centelloside production from cultured plants of Centella asiatica by combination of thidiazuron and methyl jasmonate

Yoo, Nam-Hee,Kim, Ok-Tae,Kim, Jung-Bong,Kim, Sun-Hee,Kim, Young-Chang,Bang, Kyong-Hwan,Hyun, Dong-Yun,Cha, Seon-Woo,Kim, Min-Young,Hwang, Baik The Korean Society of Plant Biotechnology 2011 Plant biotechnology reports Vol.5 No.3

In order to produce centellosides from whole plant cultures of Centella asiatica (L.) Urban, we evaluated the synergistic effects of thidiazuron (TDZ) and methyl jasmonate (MJ) on whole plant growth and centelloside production. After 4 weeks of treatment with 0.025 mg/L of TDZ coupled with 0.1 mM MJ, the production of made-cassoside and asiaticoside from whole plant cultures was estimated to be 2.40- and 2.44-fold, respectively, above that of MJ elicitation alone. When whole plants were treated with a growth regulator and an elicitor, the growth of whole plants, as compared to the controls, did not differ. Additionally, total phytosyterol content in the leaves of whole plants co-treated with MJ and TDZ was 1.08-fold greater than those of MJ alone. These results demonstrate that combined treatments not only stimulate the accumulation of centellosides in the leaves but also inhibit the reduction of phytosterol levels caused by MJ elicitation.

기능성 소금 섭취가 실험쥐의 혈중 콜레스테롤, 중성지방, 인슐린과 염소 농도에 미치는 영향에 대한 메타분석

허선희(Seon-Hee Heo),유성모(Seongmo Yoo),허선화(Seon-Hwa Heo),윤혜영(Hye Yung Yoon) 한국식품영양과학회 2018 한국식품영양과학회지 Vol.47 No.2

본 연구는 정제염 섭취에 비하여 기능성 소금 섭취가 혈중지질, 인슐린, 염소 농도에 미치는 영향을 파악하는 것이다. 이를 위해서 정제염 대 기능성 소금을 대상으로 메타분석을 통하여 총 콜레스테롤, 중성지방, 고밀도지단백 콜레스테롤, 인슐린, 나트륨 농도와 같은 혈중 성분 관련 척도 일평균 체중증가량과 식이효율과 같은 체중 관련 척도에 미치는 효과 크기를 비교하였다. 정제염 섭취에 비하여 기능성 소금섭취는 총 콜레스테롤과 중성지방의 감소에 효과적인 것으로 나타났으며, 혈중 인슐린 농도 증가에 효과적인 것으로 나타났다. 하지만 고밀도지단백 콜레스테롤의 증가에 영향을 미친다는 증거는 발견되지 않았다. 혈중 Na⁺ 농도의 경우 정제염 섭취와 기능성 소금 섭취의 차이는 발견되지 않았으며, Cl⁻ 농도의 경우 정제염 섭취에 비하여 기능성 소금 섭취의 경우 농도가 유의미하게 감소하는 효과가 있는 것으로 나타났다. 기능성 소금 섭취로 인한 중성지방 감소는 기능성 소금 섭취가 체내 중성지질의 배설을 촉진시킴으로써 혈중 전체 콜레스테롤 농도를 낮추는 효과가 있는 것으로 판단된다. 순수 NaCl로 구성되어 있는 정제염은 혈중 미네랄을 감소시키기 때문에 과다 섭취 시 신체에 유해한 것으로 알려져 있으며, 소금 성분 중 Na⁺과 Cl⁻ 중 어느 성분이 고혈압과 관련이 되었는지에 대하여는 아직 명확하게 규명되지 않은 상태이다. 기능성 소금 섭취는 삼투압 작용과 관련이 있는 세포 밖 Na⁺ 농도를 정제염과 차이가 없게 유지시키고 있으며, 혈관수축과 관련이 있는 Cl⁻ 농도를 감소시키는 것으로 나타난 메타분석 결과는 기능성 소금 섭취가 인체의 항상성 유지를 위한 삼투압 작용은 유지하면서 혈관수축을 유발하는 염소 농도를 감소시키는 효과가 있다는 것을 의미한다. 기능성 소금 섭취가 인슐린 증가를 유도하는 것은 기능성 소금에 함유된 Mg 같은 미네랄 성분으로 인한 것이며, 인슐린 증가는 혈당 감소에 영향을 미치게 된다. 이상의 결과에서 기능성 소금 섭취는 삼투압 작용에 필수적인 Na⁺ 농도는 유지하면서, 혈중 중성지방 배출을 통한 혈중 콜레스테롤 감소와 인슐린 증가를 통한 혈당 감소의 효과가 있는 것으로 확인되었다. 따라서 본 연구 결과를 토대로 기능성 소금 섭취가 혈중 콜레스테롤 감소, 인슐린 농도 증가, Cl⁻ 농도 감소에 효과적인 것으로 나타나 정제염 대신 기능성 소금 섭취를 권장할 수 있을 것으로 생각되나 본 연구의 메타분석에 사용된 학술 논문의 수가 적기 때문에 향후 지속적인 in vivo관련 연구를 통하여 기능성 소금 섭취의 긍정적인 효과에 대한 증거 누적과 의학적인 기전 규명에 대한 연구도 필요할 것으로 생각된다. 아울러 메타분석에 사용된 개별연구에서의 연구대상이 정상 쥐, 당뇨 쥐, 고혈압 쥐 등으로 이질적이지만 개별연구의 수가 적어서 연구대상의 조절 효과를 다룰 수가 없었으며, 향후 관련된 연구가 누적될 경우 이에 대한 연구도 필요할 것으로 생각된다. It is publicly recommended to intake less sodium if possible. However, it is inevitable to intake salt in daily life, especially in Korea, and there are various kinds of functional salts for replacing table salts. The objective of this study was to assess the effects of functional salt intake on levels of total cholesterol, triglyceride, high-density lipoprotein cholesterol, insulin, sodium, and chloride in the blood of rats using meta-analysis. Individual research materials were selected from academic databases such as MEDLINE, Science Direct, CINAHL, DBPIA, and KISS. Research articles published in peer-reviewed academic journals that compared purified salt and functional salts such as bamboo salts and mineral-rich salts and that experimented with a nonequivalent control group research design were selected. Two authors independently selected final articles, and only four articles were qualified for the meta-analysis. Hedges’ effect size was used to compare functional salts and purified salts. The results show that the effect size of total cholesterol, triglyceride, insulin, and chloride measures were significantly different from zero. The results imply that functional salts are possibly effective in decreasing total cholesterol, triglyceride, and chloride and increasing insulin in blood.

방사성요오드 치료를 받는 갑상선암 환자의 삶의 질 변화와 영향요인

유선희(Yoo, Seon Hee),최스미(Choi-Kwon, Smi) 한국간호과학회 2013 Journal of Korean Academy of Nursing Vol.43 No.6

Purpose: To investigate changes in Quality of life (QOL) and related factors in patients with thyroid cancer undergoing Radioactive Iodine remnant ablation (RAI). Methods: Data were collected longitudinally 3 times for 6 months (2 weeks post-surgery, post RAI, 3 months post RAI) in a hospital located in Seoul. Questionnaires were used to measure levels of physical symptoms, anxiety, depression, and QOL. Ninety-eight patients with thyroid cancer who had RAI were included in the analysis. Data were analyzed using SPSS (18.0). Results: Findings for the three data collection times respectfully were: mean scores for physical symptoms, 0.53, 1.21 and 0.62, patients with depression, 47%, 36.7% and 37.7%, patients with anxiety, 18.4 %, 19.4% and 20.4%, mean scores for QOL, 7.06, 7.01 and 7.28. QOL score was highest 3 months post RAI (p=.031). In the stepwise multiple regression analysis, depression and fatigue were predicting factors for low QOL at all data collection times. Dysponia was a predicting factor for low QOL post RAI and 3 months post RAI. Conclusion: To increase QOL, it is necessary to provide information in advance regarding physical & psychological symptoms and to develop nursing intervention programs to decrease depression and fatigue.

Adie 증후군과 동반된 원발성 Sjogren 증후군

김선희 ( Seon Hee Kim ),김영학 ( Young Hak Kim ),조유숙 ( You Sook Cho ),김찬 ( Chan Kim ),최승원 ( Seung Won Choi ),유빈 ( Bin Yoo ),이명종 ( Myoung Chong Lee ),문희범 ( Hee Bom Moon ) 대한류마티스학회 1995 대한류마티스학회지 Vol.2 No.2

Sjogren`s syndrome is a heterogenous autoimmune disease characterized by progressive destruction of the exocrine glands and accompanied by a variety of autoimmune phenomena. Sjogren`s syndrome patients can develop symptoms of ocular and oral dryness as well as extraglandular complications including central and peripheral nervous system disease. Sometimes neuropathy precedes the diagnosis of Sjogren`s syndrome. Adie`s syndrome is characterized by tonic pupil and the absence of tendon reflex. Sweating abnormality and chronic peripheral polyneuropathy can also be present. We report a case of primary Sjogren`s syndrome preceded by Adie`s syndrome with peripheral neuropathy. A 26-year-old woman was admitted for photophobia and paresthesia. On examination. her pupils were anisocoric and did not react to light but constricted promptly to pilocarpin. Sensation decreased on her left side of body and deep tendon reflexes were absent. Biopsy of minor salivary gland demonstrated infiltration by lymphocyte consistent with Sjogren`s syndrome, but Schirmer test was negative. So she was diagnosed as Adie`s syndrome with peripheral neuropathy. Five month later she complained of dry eye and dizziness. Rose bengal staining was positive. Sjogren`s syndrome was diagnosed and she was discharged with local therapy for the sicca symptoms.

실거래가를 활용한 개별공시지가의 형평성 분석연구

유선종(Yoo, Seon-Jong),이주희(Lee, Joo-Hee),정희남(Jung, Hee-Nam) 한국주거환경학회 2014 주거환경(한국주거환경학회논문집) Vol.12 No.3

The Publicly Announced Price (PAP) of individual land, introduced in 1989 and assessed by local governments every year, has been used as a criterion for levying land taxes, including property tax and capital gains tax. There have been arguments about whether the PAP of land is reliable and appropriate to represent the market prices. The arguments become even hotter since 2006 when the government introduced the real price report system in real estate transaction. Tax equity, both horizontal and vertical equity, means the similar amount of tax shall be levied being proportioned to the similar value of property. This study is to identify whether there exists the equity among land tax bases, that is PAP of individual land. Effective 1,168 parcels of land was selected from Bupyung-gu, Incheon City, which were traded during the years of 2011 and 2012. It compares the difference between the PAP of individual land and the reported transaction prices. To analyze both the horizontal and vertical equity of each 8 local counties (dong) and value level, it uses the ratio analysis method and regression analysis. The findings can be summarized as follows; there exists vertical inequity in most local counties and land value levels. It implies land taxes were rather degressive. There also exists horizontal inequity, implying tax burdens do not proportionally allocated to similar land conditions. The findings suggest that improving the PAP of land system is necessary to enhance both the vertical and horizontal equity.