영·유아 언어, 인지, 사회·정서 발달 평가도구 문항 개발을 위한 예비연구

이종숙,신은수,박은혜,김영태,유영의,최일선,유흥옥 이화여자대학교 교육과학연구소 2009 교육과학연구 Vol.40 No.3

본 연구는 만 2~5세 영·유아의 발달 상태를 객관적으로 평가함과 동시에 발달이 지연된 영·유아를 선별할 수 있는 발달평가도구 문항을 개발하기 위한 예비연구이다. 이를 위해 문헌고찰 및 발달관련 평가도구들을 비교 분석하여 발달지표를 선정하고, 만 2세~5세까지의 영·유아의 언어, 인지, 사회·정서발달영역을 교사관찰에 기초하여 평가할 수 있는 문항을 개발하였다. 연구대상은 대도시, 중소도시, 읍면 소재지 별로 표집 된 만 2세부터 5세까지 총 13개 유아교육기관에 다니는 435명의 영·유아들이며, 본 연구에서 최종 개발된 평가도구의 문항은 총 141문항이다. 평가도구 문항은 언어, 인지, 사회·정서발달영역별로 영·유아의 행동과 언어를 중심으로 교사가 관찰하고, 관찰하기 어려운 문항에 대해서는 단서와 kit를 제시하여 평가할 수 있도록 구성하였다. 개발된 평가도구 문항의 적절성을 알아보기 위하여 내용 타당도와 내적 신뢰도를 살펴본 결과 비교적 양호한 것으로 나타났다. This was a preliminary study to construct a developmental rating scale for understanding children's objective developmental levels and screening developmental disabilities. For this purpose, a developmental indicator was selected by a literature review and comparative analysis of related developmental assessment tests. An assessment scale based on teacher's observations to measure language, recognition, and social-emotional developmental areas was developed. The subjects were 435 young children aged 2 to 5 who lived in both urban and rural areas. A trial test consisted of 141 assessment items in the language, recognition, and social-emotional developmental domains. The developmental scale was evaluated by teachers who observed children's behavior and language, and used clues and kits. Tests on validity and reliability for confirming the appropriateness of the developed assessment scale showed that content was relatively valid and internally consistent.

苛性소다 處理가 볏짚의 나이론주머니 消化率에 미치는 영향

辛炯泰,金永玉,魏筍英 成均館大學校 1980 論文集 Vol.28 No.-

Four Korean native male goats, weighing approximately 30㎏ each, were equipped with rumen cannulas to study the effect of different levels of NaOH treatment, of rumen incubation time and of different kinds on "nylon bag dry matter digestibility (NBDMD,%)" and "nylon bag organic matter digestibility (NBOMD,%)" of rice straws. The goat was housed individually in pen and was fed 600 grams (concentrate) daily, and fed rice straw and rincal blocks ad libiltum. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9 X 14 ㎝ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 24, 48 and 72 hours (Experiment 1) and 72 hours only (Experiment 2). They were washed, dried in an oven at 105℃ for 24 hours and weighed "NBDMD", and ashed in an muffle furnance at 600℃ for 2 hours and weighed "NBOMD". The results which were obtained with two experiments were as follows; 1. Nylon bag dry matter digestibility (NBDMD,%) and nylon bag organic matter digestibility (NBOMD,%) of NaOH treated straws were highly significant different (P<0.01) in different levels of NaOH treatment, of rumen incubation time and of different kinds of rice straws. 2. The relationship between mean NBDMD (%, Y_1) of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hours rumen incubation was: Y_1=2.93X_1+42.32(r=0.97^**) 3. The relationship between mean NBOMD (%, Y_2)of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hour rumen incubation was: Y_2=2.76X_1+41.32(r=0.96^**) 4. The orders of NBDMD (%) and NBOMD (%) for 5 kinds fo rice straws were Yooshin, Suwon 264, Milyang 23, Tongil and Akibre. Therefoare it is necessary to study more on the utilization of NaOH-treated new-bred rice straws for animal performance than old-bred rice straw as Akibare. 5. The optimal level of NaOH (%) for improving NBDMD and NBOMD from 5 kinds of rice straw on the basis of Dr. McCullough's theory was as follow: 6% NaOH for Yooshin, Suwon 264 and Milyang 23; 7% NaOH for Tongil and 8% NaOH for Akibare. 6. Crude protein, crude fiber, ADF, cellulose, lignin percent of 5 rice straws did not much different by chemical analysis. The orders of NBDMD (%) and NBOMD (%) for 5 kinds of rice straws did not same orders of the consitituents of chemical composition in rice straws.

피하기종,기종격을 동반한 제초제 중독 1례

신준섭,최옥경,정구영 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Paraquat(1,1-dimethyl-4,4-bipyridium dichloride) is lethal herbicide and it is thought to act by turning into superoxide and peroxide free radical in the presence of reducing agents. Among the multiple organ failure, the pulmonary complication is always fatal. We present the case of a patient with subcutaneous emphysema and pneumomediastinum without pneumothorax on 6days later after acute paraquat ingestion. A 28 years old female patient was admitted ED at 10:40 on September 8, 1995(Day 1) after ingestion of 10cc-15cc of paraquat (20% solution) at 20:00 on yesterday. By the sodium dithionite test, the presence of paraquat was negative in the urine. She was alert without oropharyngeal ulceration and had stable vital signs. Her hepatic function was moderately deteriorated (SGOT/SGPT 389/867, ALP 233, TB 5.7) and the others laboratory findings were normal limits. She was transferred to ICU and treatment was according to a our protocole(Table 1). On day 6, she complainted numbness on the right lateral neck and respiratory difficulty. The chest X-ray showed subcutaneous emphysema, pneumomediastinum and pneumomediastinum without pneumothorax. Day after day, the size of subcutaneous emphysema and pneumomediastinum were decreased on chest x-ray and it was not found inflammatory signs. The chest CT showed pulmonary fibrosis on the both lower lung field(onday 10) and the esophagography showed no specific findings without dye leakage(on day 14). On day 16, The high resolution chest CT was showed diffuse pulmonary opacity with cystic lesions and peribronchovascular air densities were found with pericardial emphysema and pneumomediastinum. At 4:30 a.m. on day 18, the respiratory arrest was developed and she was expired at 4:35 a.m. under DNR.

RBL-2H3 세포에서 Spermine에 의한 히스타민 유리와 칼슘유입에 미치는 상백피의억제효과

채옥희,강경진,신인호,김영기,이무삼,전병득 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2

蛋白質 供給源이 흰쥐의 成長 및 窒素均衡에 미치는 影響

辛炯泰,金永玉 成均館大學校 科學技術硏究所 1985 論文集 Vol.36 No.1

This experiment was conducted to study the effect of protein supplementation to rice diet on growth, digestibility, nitrogen balance and nitrogen retention by growing rats. The experimental diets were consisted of rice diet (no supplementation of protein, I), soybean meal diet (II ), casein diet (III), fish meal diet (Ⅳ), lysine+threonine diet (V), 1/2 soybean meal+1/2casein diet (Ⅵ), 1/2 soybean meal+1/2fish meal diet (VII). Experiment was undertaken with 42 weanling male rats of Sprague-Dawley strain for 3 weeks and they were evenly divided by 7 treatments, respectively and feeds and clean water were available ad libitum. For the experimental period, body weight gain, feed intake, feed efficiency ratio, protein efficiency ratio, digestibility (dry matter, organic matter, crude protein), nitrogen balance and nitrogen retention were measured to evaluate the nutritional effects of protein sources. Some results which were obtained with this experiment as follows: 1. The average daily body weight gain for growing rats fed experimental diets(I-VII) were 0.95g, 2.03g, 2.97g, 3.27g, 2.48g, 2.71g, 2.77g, respectively. The highest body weight gain was fish meal diet (IV) and the lowest was sodbean meal diet (II). And the other diets ( III , V,Ⅵ,VII) showed similar weight gains. 2. Feed efficiency ratio (FER) was higher for fish meal diet (IV) and casein diet (III) than the other diets. And feed efficiency ratio of the other diets were similar. 3. Protien efficiency ratio (PER) followed the same pattern as the feed efficiency ratio. 4. Digestibilities of dry matter and organic matter were for casein diet (III) of 94.07%, 96.01%, respectively and soybean meal diet (II) of digestibilities of dry matter and organic matter 91.59%, 93.98% respectively. Protein digestibility showed the same pattern as the protein efficiency ratio. 5. The nitrogen balance and nitrogen retention of fish meal diet (Ⅳ) were higher than those of the rest of diets and soybean meal diet (II) was shown the lowest values. 6. As studies with rice diets by growing rats, protein supplementation to rice was superior to unsup plemented diet in performance, nitrogen balance and nitrogen retention. To compare the nutritional values of protein sources in this experiment, fish meal and casein as animal protein sources showed the highest performance, nitrogen balance and nitrogen retention. Combined animal protein and plant protein and lysine+threonine supplementation were the middle (performance, nitrogen balance and nitrogen retention) and soybean meal as plant protein showed the least (performance, nitrogen balance and nitrogen retention).

국내산 양송이, 느타리, 표고 버섯의 휘발성 향미 특성 : Agaricus bisporus, Pleurotus ostreatus, and Lentinus edodes

신길옥,김영석 이화여자대학교 생활환경대학 인간생활환경연구소 2002 인간생활환경연구소 논집 Vol.- No.1

Volatile compounds in Agaricus bisporus, Pleurotus ostreatus and Lentinus edodes cultivated in Korea were analyzed by using gas chromatography/mass spectrometry (GC-MS) and gas chromatography/olfactometry (GCO). A total of 108, 103, and 122 volatile compounds were identified in Agaricus bisporus, Pleurotus ostreatus and Lentinus edodes, respectively. Some odorants, such as butanoic acid (described as strong rancid), 2-methyl butanoic acid (described as stinky), 3-methyl butanoic acid (described as buttery), 2-heptanol (described as grassy), 2-pentanol (described as green), trans-2-heptanal (described as fatty), trans, trans-2,4-octadienal (described as grassy), 1-octen-3-one (described as fresh mushroom-like) and 1-octen-3-ol (described as mushroom-like) were found in all the samples. The unique odor compounds of each mushroom were benzaldehyde (described as almond) and benzyl alcohol (described as floral) in Agaricus bisporus, 2-formyl-5-methylthiophene (described as strong sulfurous) in Lentinus edodes, and unknown compounds (described as spicy) in Pleurotus ostreatus.

외이도에 발생한 악성종양의 치료 결과

최영석, 신시옥 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

연구목적 : 외이도에 발생하는 악성종양의 임상적 특징 및 병기에 따른 치료효과를 비교하고자 한다. 대상 및 방법 : 1996년부터 2005년까지 10년간 충북대학교병원에서 외이도 악성종양으로 진단 받고 치료 후 추적관찰이 된 11명의 환자들을 대상으로 연령별, 성별 분포, 병기의 분류 및 병기에 따른 치 료 결과를 확인 하였다. 결과 : 총 11례의 환자 중 남자와 여자의 비는 9:2로 남자에게서 발병율이 월등히 높았으며 나이 분 표는 20대에서 80대까지 다양하게 분포되었고 50대에서 가장 호발 하였다. 병기에 따른 치료결과로는 수술적 치료가 우선 되었던 T1, T2의 경우 5년 생존율이 86%이었으며 방사선 치료가 주치료였던 T3, T4의 경우 5년 생존율이 50%이었다. 조직학적 특성으로는 편평상피암이 9례(82%)로 대부분이 었으며 선양낭성암종과 기저세포암이 각각 1례씩이었다. 결론 : 외이도의 악성종양은 T병기 별로 유의한 5년 생존율의 차이를 보이며 조기발견 및 암종의 침 습정도를 정확히 파악하고 수술시 절제변연을 충분히 확보하는 것이 중요하다.

消石灰處理가 볏짚의 粗成分 및 消化率에 미치는 影響에 관한 硏究

辛炯泰,魏筍英,金永玉 成均館大學校 1981 論文集 Vol.29 No.-

Nylon bag dry matter digestibility (NBDMD, %), nylon bag organic matter digestibility (NBDMD, %) and chemical compositions were analysed to evaluate the nutritive values of 5 varieties of Ca(OH)_2-treated rice straws (Akibare, Tongil, Milyang 23, Yooshin and Suwon 264) by using Korean native male goats. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9×14 ㎠ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 72 hours. They were washed, dried in an oven at 105℃ for 24 hours and weighed "NBDMD" (%) and ashed in an muffle furnace at 600℃ for 2 hours and weighed "NBOMD" (%). The results which were obtained with this experiment were as follows : 1. Nylon bag dry matter digestibility (NBDMD, %) and nylon bag organic matter digestibility (NBOMD, %) of Ca(OH)_2-treated rice straws were highly significant different (p<0.01) in different levels of Ca(OH)_2 treatment and of different varieties of rice straws. 2. The relationship between total mean NBDMD (%, Y_1) of 5 varieties of rice straws and Ca (OH)_2 concentration (%, X) at 72 hours rumen incubation was : Y_1=1.51X+41.36 (r=0.97^**) 3. The relationship between total mean NBOMD (%, Y_2) of 5 varieties of rice straws and Ca(OH)_2 concentration (%, X) at 72 hours rumen incubation was : Y_2=1.36X+41.02 (r=0.95^**) 4. The orders of NBDMD (%) and NBOMD (%) for 5 varieties of rice straws were Yooshin, Suwon 264, Milyang 23, Tongil and Akibare, and Yooshin showed the highest values and Akibare showed the lowest values. Crude fiber, cell-wall constituents and lignin percent in the five varieties of rice straws were shown the negative relation to the NBDMD (%) and NBOMD (%).

이성대상포진의 증상에 따른 안면신경마비의 정도와 예후

신시옥,송창근,이동욱,최영석,진흥률,신정우,윤희석 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.1

연구목적: 이성대상포진에 동반되는 안면신경마비는 Bell's palsy와는 달리 예후가 더 나쁘고 그 마비가 완전히 회복되지 않는 경우가 더 많다.본 연구에서는 이성대상포진에서 발현되는 증상들의 유무가 치료 전 안면신경마비의 정도 및 치료 후 예후와 상관관계가 있는지를 관찰하여 예후의 예측인자에 대해 분석하였다. 재료 및 방법: 지난 1992년 1월부터 1999년 6월까지 이성대상포진으로 진단받고 본원에 입원하여 고용량 부신피질호르몬제와 항바이러스제인 acyclovir의 병합투여로 동일한 치료를 받은 30명의 환자를 대상으로 후향적으로 의무기록을 분석 및 고찰하였으며, 치료 전 안면마비의 정도와 치료 후 마비의 회복 정도를 이통, 이명, 난청, 현훈 등의 증상의 유무와 치료 시작 시기, 그리고 안면신경의 electroneuronography(ENoG) 값에 따라 비교하였다. 결과: 이성대상포진수포가 안면신경마비 보다 먼저 발현된 경우에 안면신경마비의 치료 전 grade가 통계적으로 유의하게 좋았다(p<0.05).이통, 청력손실, 그리고 현훈의 유무에 따른 안면신경마비의 정도는 상관관계가 없었고 예후에도 차이가 없었다.이명의 유무에 따른 치료 전 안면신경마비의 정도는 상관관계가 없었으나 치료 후 완전회복율은 이명이 있었던 군에서 통계적으로 유의하게 높았다(p=0.003<0.05).완전회복군과 불완전회복군 사이의 치료 전 ENoG의 수치는 통계적으로 유의하게 예후와 상관이 있었다(p=0.037<0.05). 결론: 좀더 많은 수의 환자를 연구에 포함하여 증상에 따른 예후의 차이를 연구하는 것이 필 요하며 또한 ENoG 값이 10%에서 40% 사이인 환자들의 치료 방법에 대한 고려와 이성대상포진수포가 안면신경마비보다 먼저 생긴 환자에서 치료 전 마비정도가 경미했던 이유에 대한 연구가 필요할 것으로 생각된다. Purpose: Herpes zoster oticus generally has a poor prognosis, leaving many patients with permanent facial nerve dysfunction, compare to Bell's palsy.Acyclovir and prednisolone have been widely used for the treatment of herpes zoster oticus.This retrospective study was conducted to suggest the prognostic factors according to various symptoms. Materials and Methods : Clinical studies were retrospectively performed on 30 patients with herpes zoster oticus who were treated with acyclovir and prednisolone in the Chungbuk National University Hospital between 1991 and 1999.The authors analyze the pre-treatment grade and prognosis of facial nerve palsy according to symptoms(the existence of otalgia, tinnitus, hearing loss, and vertigo), the treatment onset, and electroneuronography ( ENoG ). Results : Of thirty patients who have been diagnosed as herpes zoster oticus, there is no significant difference in the pre-treatment grade of facial nerve palsy according to the existence of vesicle, otalgia, tinnitus, vertigo, and hearing loss.Of 25 patients who have facial nerve palsy, the recovery from the palsy is complete in 14 patients(56%).There is no significant difference in the pre-treatment grade of facial nerve palsy according to the existence of otalgia, tinnitus, vertigo, and hearing loss.The pre-treatment grade of facial palsy is better when the vesicles precede facial in the group with tinnitus than without tinnitus.A significant difference of the prognosis according to the onset of treatment and other symptoms are not found.ENoG is better in the group that facial nerve palsy is completely recovered than incomplete recovery group. Conclusion : Reliable prognostic factor according to symptoms is not found, ENoG is the only prognostic factor.

姙娠末期 및 哺乳期 飼料의 아미노산 補强이 母豚의 生産性 및 仔豚成長에 미치는 影響

辛炯泰,金永玉 成均館大學校 科學技術硏究所 1988 論文集 Vol.39 No.1

This experiment was conducted to study the effect of amino acid supplementation to two protein level of corn-soybean meal diets fed in late-pregnancy and lactation on the performance of sows and their litters. The experimental diets were consisted of 13% protein diet(T_1), 13% protein diet + 0.26% lysine + 0.10% methionine + 0.02% tryptophan(T_2), 15% protein diet(T_3), 15% protein diet + 0.02% tryptophan(T_4). Experiment was undertaken with 16 gestating sows for 80 days(50 days in late-pregnancy period and 30 days in lactation period). Some results watch were obtained with this experiment as follows: 1. There were no differences in body weight change of gestating sows during late pregnancy among the treatments. 2. Numbers of live-born piglets at birth were similar among the treatments. Birth weight of piglets by gestating sows fed 15% protein diet + 0.02% tryptophan(T_4) was the highest, but there were no significantly different among the treatments(P>0.05). 3. The highest weaning piglet body weigiht was 15% protein diet + 0.02% tryptophan (T_4) and the lowest was 13% proten diet(T_1). 4. the body weight change of lactating sows during lactation was affected by milk yield. Lactation weight loss was greater for sows receiving 13% protein diet(T_1) and lesser for 15% protein diet + 0.02% tryptophan(T_4). So, it may be concluded that tryptophan(0.02%) supplementation to 15% protein diet for late-pregnancy and lactation period would be the best performances. Lysine, methionine, tryptophan supplemention to 13% protein diet and 15% protein diet in late-pregnancy and lactation showed similar performances of sows and litters.