저유량 마취를 위한 전자제어식 기화기 개발

오영택,박재훈,장인배 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.B

For the environmental safety of the operating room and patient healthcare, the closed type rebreathing system is widely adopted. In order to reduce the anesthesia gas during surgery, the mixing ratio of anesthesia gas with breathing air should be precisely controlled. Generally, the breathing air passes through the vaporizer to mix the anesthesia gas, but there is a difficulty in controlling the mixing ratio precisely. In this paper, the stand-alone style vaporizer is designed and the operating characteristics are investigated. The vaporizer measures the temperature and pressure in the vaporizing chamber and chamber temperature is precisely controlled by proportional controlled heater. Exact quantity of anesthesia media is feeded by PID controlled peristaltic pump and vaporized gas is mixed with breathing air flow by PWM controlled solenoid valve. The experimental result shows that the vaporizer has an excellent command following performances that it can be applied to the low flow anesthesia system.

GSIS를 이용한 소하천 경계경보 발령기준 설정 및 관리방안에 관한 연구

오명진,박재훈 경복대학 2004 京福論叢 Vol.8 No.-

최근 홍수피해의 문제점을 분석해 보면 기상 이변으로 집중호우가 발생하고 특히, 국지적인 호우에 의한 돌발홍수(flash flood)로 인한 피해가 빈번하게 발생하고 있다. 대하천의 경우에는 각 홍수 통제소에 의한 홍수 예·경보시스템(flood warning system)을 통하여 인명 혹은 재산피해는 과거에 비하여 상당히 감소하였으나 소하천에서는 반대로 피해가 증가하고 있는 실정이다. 본 연구에서는 하천 지역의 돌발홍수의 특성을 밝혀 보고자 지형공간정보(GSIS, Geo-Spatial Information System)기법을 이용하였으며, 하천 유역의 수문학적 돌발홍수 예측모형을 GIUH(geomorphoclimatic instantaneous unit hydrograph) 기법으로 구축하였다. 본 연구를 통하여 구축된 돌발홍수 예·경보 시스템을 통하여 하천 지역에 있어서의 인명 및 재산피해를 상당부분 감소시킬 수 있을 것이며, 다른 지역의 돌발홍수 예·경보 시스템구축을 위한 기초 자료를 제공할 수 있을 것이다. Recently, local heavy rain for a short term is caused by unusual changing in the weather. This phenomenon has, several times, caused an extensive flash flood, casualties, and material damage. In case of large river, the extent of loss of lives and properties has been decreased through the flood warning system by flood control stations. However, the extent of damages in other small rivers has increased to the contrary. This study is aimed at calculating the characteristics of flash floods in streams. For this purpose, the anslysis of topographical characteristics of water basin through applying GSlS techniques will be conducted. The flash flood prediction model we used is made with GIUH(geomorphoclimatic instantaneous unit hydrograph). As a result, we can suggest a rational warning criteria for the mitigation of flash flood damage and the reduction of the casualties as well as those for the decrease of property damage. Therefore, it will provide basic materials to establish a new flash food warning system, which can replace current system for other places.

自然型 接觸酸化法에 의한 都市下水 處理에 關한 硏究

오종민,김무훈,윤동선,박재영 경희대학교 산학협력기술연구원 1997 산학협력기술연구논문집 Vol.3 No.-

This study was performed to estimate the organic matter removal efficiency when apply to natural purification method with variable media. We used gravel, concrete, tire, scrubber as media of contact oxidation reactor. And when scrubber, gravel, the average SS, BOD, COD removal efficiency was very high(when scrubber, 96.3, 78.1, 59.0 % and gravel, 82.1, 73.8, 56.5 %, respectively). If the physical and chemical operations are added to contact oxidation process for the removal of nitrogen, phosphorous, the water quality of urban small stream which is polluted by municipal waste water will be purified.

Al-Ti-Cr 합금계 L1_2기지 합금의 800℃에서의 상안정성

오민욱,이재경,오명훈,위당문 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.1

Relationship between the phase stability and the composition of L1_2-based Ti-Al-Cr alloys at 800℃ was investigated. It was found that the yield strength of Al-21Ti-23Cr and Al-21Ti-15Cr alloys with Ti-lean composition after exposure at 800℃showed a relatively small increase compared with that of alloys homogenized at 1150℃. However, yield strength of al-30Ti-15Cr alloy with Ti-rich composition after exposure at 800℃ increased very remarkably. The difference in strength increment after exposure at 800℃ was due to the partial decomposition of L1_2 phase in Al-21Ti-23Cr and Al-21Ti-15Cr alloys, and the complete decomposition of L1_2 phase in al-30Ti-15Cr alloy. Therefore, alloys with Ti-lean composition were expected more suitable for light heat resistant and oxidation resistant coating material with respect to stability of L1_2 phase. It was also revealed that the phase decomposition of L1_2 phase resulted from the shift of L1_2 phase region to Al-rich corner in Al-Ti-Cr phase diagram with decreasing temperature.

외음부에 발생한 혈관근육섬유아세포종 1례

오혜근,구자봉,김동출,심재영,박정훈,박영균,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

We present a case of angiomyofibroblastoma of the vulva in a 32-year-old woman. The asymptomatic lesion measured 4×3cm and appeared as a gray-white myxoid mass on cut sections Histologically, it appeared as a relatively well-circumscribed spindle cell proliferation with alternating hypercellular and hypocellular areas and proliferation of thin-walled blood vessels. Immunohistochemically, the stromal cells expressed vimentin, CD34 and progesterone receptor, but not desmin, α-smooth muscle actin, S-100 protein and estrogen receptor. These features were similar to those of angiomyofibroblastoma as previously reported in the vulva except negativity for desmin A case of pathologically proven very rare tumor of angiomyofibroblastoma of the vulva is presented with a literature review

폐렴구균의 용혈능 변화와 pneumolysin 유전자의 변이 양상

오원섭,장현하,정숙인,김연숙,이혁,김신우,김성민,백경란,이남용,송재훈 대한화학요법학회 2002 대한화학요법학회지 Vol.20 No.3

목적 : 폐렴구균은 인체에서 폐렴, 수막염 및 패혈증 등을 일으키는 중요한 병원균으로 현재 전 세계적으로 항균제 내성이 큰 문제가 되고 있다. 하지만 폐렴구균의 항균제 내성에 따라 병독성이 어떻게 변화하는지에 대해서는 구체적으로 알려져 있지 않다. 이에 기능적 및 구조적 분석을 통하여 폐렴구균의 주요 병독성 인자인 pneumolysin의 병인론적 역할을 규명하고자 하였다. 방법 : 임상 검체에서 분리된 페니실링 감수성 균주 20주와 내성 균주 20주를 대상으로 하였다. Pneumolysin의 세포 독성의 변화를 관찰하기 위하여 각각의 균주들의 용혈능을 측정하였고, pneumolysin 유전자를 중합효소 연쇄반응으로 증폭한 후 증폭 산물의 유전자 구조를 분석하였다. 결과 : 페니실린 감수성 균주와 내성 균주간의 용혈능은 유의한 차이를 보이지 않았으나, 일부 용혈능이 매우 낮은 균주에서 Lys152→Thr, Thr-172→Ile, Lys-224→Arg와 같은 변이가 관찰되었다. 결론: pneumolysin의 세포 독성의 변화는 항균제 내성 정도와는 무관하였으나, 일부 용혈능이 저하된 균주에서 발견된 pneumolysin 유전자의 변이가 pneumolysin의 세포 독성에 영향을 주는 것으로 보인다. Background : Pnumolysin (Ply) is one of the most important virulence factors of Streptococcus pneumoniae. To investigate the functional and structural variation of Ply, hemolytic activity (HA) and gene sequences of pneumolvsin were determined. Methods : A total of 40 invasive pneumococcal isolated (20 penicillin-susceptible & 20-resistant strains) were analyzed. HA of each isolate was measured in crude extracts (1×10^8 CFU/mL) hourly from the time of inoculation to 9h. Crude extracts (50㎕) and DTT buffer (100㎕) were serially diluted in 96-well plate and mixed with 1% sheep blood (50㎕). HA was represented as the reciprocal of the greatest dilution, which resulted in the complete lysis. Two sets of oligonucleotide primers were used to amplify a 1,474-bp fragment containing the coding region and a 578-bp fragment of upstream region of ply gene, respectively. Amplified products were directly sequenced. Results : HA showed a wide variation from 0 to 87,480 regardiess of penicillin MICs, serotypes or specimen sources. Two bacteremic strains showed completely no hemolytic activity. No significant differences in HA between penicillin-susceptible (Mean± SE : 15,468± 4,693) and penicillin-resistant strains (21,384± 4,087) were found (p > 0.05).Sequencing of the coding region showed unique alterations in amino acids in strains with markedly reduced hemolytic activity (≤ 40): Thr-172-Ile and Lys-224-Arg. However, upstream region of ply gene was highly conserved. Conclusions : Ply activity was not related with antibiotic resistance. Absence of HA in some strains was associated with unique alterations in amino acid sequences in ply gene. Relationnship between genomic alteration and functional changes in pneumolysin should be further investigated.

뇌경색을 동반한 Haemophilus parainfluenzae에 의한 감염성 심내막염 1예

오은영,배상수,정윤재,이창근,이혁,김성민,박승우,백경란,송재훈 대한화학요법학회 1998 대한화학요법학회지 Vol.16 No.3

저자들은 뇌경색을 동반한 H. parainfluenzae에 의한 심내마염을 ampicillin과 gentamicin의 병합요법으로 치료한 1예를 경험하였기에, 이를 문헌고찰과 함께 보고하는 바이다. We experienced a case of infective endocarditis due to Haemophilus parainfluenzae complicated by cerebral infarction. A 40 year-old woman was admitted because of right-sided hemiparesis and dysarthria, which was accompanied by high fever up to 40 C with chills. She had been suffering from low-grade fever and general weakness for one month prior to admission. Blood cultures grew H. parainfluenzae, and the brain CT scan demonstrated cerebral infarction of MCA territory. Transesophageal echocardiogram showed mitral valve prolapse with regurgitation, and no vagetation was found. She was successfully treated with ampicillin and gentamicin for six weeks. To our knowledge, this is the first case of infective endocarditis caused by H. parainfluenzae in Korea.

括數根 水溶性 蛋白質의 細胞毒性

殷載淳,鄭甲基,梁在憲,權鎭,吳贊鎬,全焄 又石大學校 1995 論文集 Vol.17 No.-

The purpose of this research was to investigate effect of water-soluble protein of Trichosanthes kirillowii(TKP) on the proliferation of human tumor cells. TKP inhibited the proliferation of HeLa cells and KHOS-NP cells. The inhibitory activity of doxorubicin on HeLa cells and its of mitomycin C on KHOS-NP cells were increased by the combination of TKP. TKP did not affect on the proliferation of Balb/c 3T3 cells, but inhibited the proliferation of mouse spleen cells and human lymphocyte at 1 ㎍/ml. These results suggest that TKP bas the cytotoxicity on HeLa and KHOS-NP cells, and increase the cytotoxicity of doxorubicin or mitomycin C.

T1급 고속 암호 시스템에 관한 연구

이훈재,류명춘,오주환 경운대학교 산업기술연구소 1998 産業技術硏究論文誌 Vol.1 No.1(A)

In this paper we propose a secure T1-rate digital image conference system which consists a stream cipher of 7-bit real adder with 2 bit carrys and a fast and stable 2-step full-duplex synchronization. And we analyze the cipher algorithm and the synchronization performance of the system.

상악전치부 심미에 대한 인식도 평가

정재훈,오상천 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

This study was undertaken to determine the Korean perception of the altered anterior dental esthetics including the lack of symmetry, the midline deviation, the gingival exposure, the inclination of incisal plane, the type of incisal plane, and the type of gingival line. 670 subjects were participated in this survey. A questionnaire accompanied by 12 sets of computer-manipulated images using 3D MAX 4.2 software was used to record the ranking of the geometric preference related to the anterior esthetic discrepancies in three or four degrees of alteration. The statistical significance of the differences between the groups was determined by a one-way ANOVA and a t-test. The results obtained were as follows: 1. The Korean perception of the anterior dental esthetics according to the subjects' occupation, sex, and age was most affected by occupation. 2. The masked image emphasizing the dentition and lips appeared stranger than the non-masked image at the same alteration. 3. The lack of symmetry, which was expressed as a unilateral discoloration of the tooth, showed incongruity in any teeth of the anterior dentition. The incongruity was more severe as the degree occurred closer to the midline, 4. The deviation of midline was showed more severe strangeness as the degree of deviation increased. However, more than half of the subjects did not perceive a deviation of 5mm. 5. During smiling, the exposure of the upper gingiva showed more severe incongruity as the degree of gingival exposure increased. 77% of the subjects perceived strangeness at the gingival exposure of 4.5mm. 6. The inclination of the incisal plane appeared stranger as the degree of inclination increased. 62% of subjects perceived strangeness at the 7.5˚ inclination of the incisal plane. 7. The type of incisal plane showed increasing strangeness in the order of convex/downward, straight/horizontal, and concave/upward. 80% of subjects perceied strangeness at concave/upward. 8. The type of gingival line was showed increasing incongruity in the order of the same, a little above, and a little under the zenith of the lateral incisor to the line joining the zenith of the central incisor and the canine. However, less than half the subjects did not perceive strangeness at any alteration of the gingival line.