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      • KCI등재

        Nonlinear supersonic aerothermoelastic analysis of as ymmetrically curved-fiber composite panels with nonuniform temperature distributions

        Yating Liu,Jingbo Duan,Yihang Gao,Buqing Xu 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.3

        The thermal buckle and flutter behaviors of the asymmetrically curved-fiber composite panel in supersonic air flow are studied in frequency and time domains. Based on the Mindlin thick plate theory, the Von Karman large-deformation assumption and the quasisteady supersonic piston theory were adopted to describe deformations and supersonic loads of the composite panel, respectively. According to Hamilton variational principle, the nonlinear aerothermoelastic equations of the asymmetrically curvilinear-fiber panel were established with frequency domain characteristics obtained by the complex mode method and time domain responses obtained by the Newmark method, respectively. After verifying the correctness of the current method, the influences of temperature gradient, curvilinear-fiber orientation and incoming airflow pressure on the static large-deflection, mode coalescence, flutter-buckling boundary, time-history responses and phase-plane plots of the composite panel were discussed in detail.

      • KCI등재

        Development of a multiplex qRT-PCR assay for detection of African swine fever virus, classical swine fever virus and porcine reproductive and respiratory syndrome virus

        Yating Chen,Kaichuang Shi,Huixin Liu,Yanwen Yin,Jing Zhao,Feng Long,Wenjun Lu,Hongbin Si 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.6

        Background: African swine fever virus (ASFV), classical swine fever virus (CSFV), and porcine reproductive and respiratory syndrome virus (PRRSV) are still prevalent in many regions of China. Co-infections make it difficult to distinguish their clinical symptoms and pathological changes. Therefore, a rapid and specific method is needed for the differential detection of these pathogens. Objectives: The aim of this study was to develop a multiplex real-time quantitative reverse transcription polymerase chain reaction (multiplex qRT-PCR) for the simultaneous differential detection of ASFV, CSFV, and PRRSV. Methods: Three pairs of primers and TaqMan probes targeting the ASFV p72 gene, CSFV 5′ untranslated region, and PRRSV ORF7 gene were designed. After optimizing the reaction conditions, including the annealing temperature, primer concentration, and probe concentration, multiplex qRT-PCR for simultaneous and differential detection of ASFV, CSFV, and PRRSV was developed. Subsequently, 1,143 clinical samples were detected to verify the practicality of the assay. Results: The multiplex qRT-PCR assay could specifically and simultaneously detect the ASFV, CSFV, and PRRSV with a detection limit of 1.78 × 100 copies for the ASFV, CSFV, and PRRSV, but could not amplify the other major porcine viruses, such as pseudorabies virus, porcine circovirus type 1 (PCV1), PCV2, PCV3, foot-and-mouth disease virus, porcine parvovirus, atypical porcine pestivirus, and Senecavirus A. The assay had good repeatability with coefficients of variation of intra- and inter-assay of less than 1.2%. Finally, the assay was used to detect 1,143 clinical samples to evaluate its practicality in the field. The positive rates of ASFV, CSFV, and PRRSV were 25.63%, 9.36%, and 17.50%, respectively. The co-infection rates of ASFV+CSFV, ASFV+PRRSV, CSFV+PRRSV, and ASFV+CSFV+PRRSV were 2.45%, 2.36%, 1.57%, and 0.17%, respectively. Conclusions: The multiplex qRT-PCR developed in this study could provide a rapid, sensitive, specific diagnostic tool for the simultaneous and differential detection of ASFV, CSFV, and PRRSV.

      • KCI등재

        Anionic trash control in high-yield pulp (HYP) containing furnish by using a poly-DADMAC based commercial formulation

        Yating Wang,Jianping Ni,Cui Chen,Jinyong Peng,Hongbin Liu 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.6

        High-yield pulp (HYP) is gaining increasing interest in papermaking, the presence of anionic trash hasbeen limiting its application in high-end paper products such as fine papers. In order to control the anionictrash ofHYP, the performances of three anionic trash catchers in terms of charge controland fiber fines andfiller retention enhancement were compared in a laboratory study. It was found that a poly-DADMACbased commercial product had the highest efficiency. The use of CPAM/Bentonite system resulted inhighest fiber fines and filler retention. The best anionic trash controlwas achieved when HYPwas treatedseparately.

      • Accelerated Life Test Study on Thyristors of HVDC Converter Valve

        Cuicui Liu,Ning Liang,Yating Gou,Jiachen Tian,Fang Zhuo,Feng Wang 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        As the key component of HVDC converter valve system, thyristors have vital impact on the reliability of the entire HVDC transmission project. In order to effectively obtain the life model of thyristor, this paper uses the existing accelerated life test theory, combined with the operating conditions of the converter valve and the relevant characteristics of the thyristors, to deeply analyse the several stress levels that have the most serious impact on the life of the thyristors. An accelerated life test scheme that can effectively guide the life model of the thyristor, according to the test data collected by this test method, the thyristor junction temperature life model under the short-circuit current stress is established, and compared with the thyristor failure rate in the practical engineering, the results show the feasibility of the test scheme and the correctness of the life model.

      • KCI등재

        Whole-genome bisulfite sequencing identified the key role of the Src family tyrosine kinases and related genes in systemic lupus erythematosus

        Fang Ting,Liu Suyi,Chen Liying,Ren Yating,Lu Dingqi,Yao Xinyi,Hong Tao,Zhang Xvfeng,Xie Zhimin,Yang Kepeng,Wang Xinchang 한국유전학회 2023 Genes & Genomics Vol.45 No.9

        Background As a multisystemic autoimmune illness, the basic mechanisms behind the pathophysiology of systemic lupus erythematosus (SLE) remain poorly understood. Objective We aimed to investigate the possible significance of SLE’s DNA methylation and gain further insight into potential SLE-related biomarkers and therapeutic targets. Methods We used whole genome bisulfite sequencing (WGBS) method to analyze DNA methylation in 4 SLE patients and 4 healthy people. Results 702 differentially methylated regions (DMRs) were identified, and 480 DMR-associated genes were annotated. We found the majority of the DMR-associated elements were enriched in repeat and gene bodies. The top 10 hub genes identified were LCK, FYB, PTK2B, LYN, CTNNB1, MAPK1, GNAQ, PRKCA, ABL1, and CD247. Compared to the control group, LCK and PTK2B had considerably decreased levels of mRNA expression in the SLE group. Receiver operating characteristic (ROC) curve suggested that LCK and PTK2B may be potential candidate biomarkers to predict SLE. Conclusions Our study improved comprehension of the DNA methylation patterns of SLE and identified potential biomarkers and therapeutic targets for SLE.

      • KCI등재

        Effect of Cu-Coated Short Carbon Fibers on the Mechanical and Electrical Properties of the Epoxy Composites

        Weiwei Li,Lei Liu,Bin Shen,Yating Wu,Wenbin Hu 한국고분자학회 2012 Macromolecular Research Vol.20 No.4

        In this study, short carbon fiber (SCF)-reinforced epoxy composites were prepared through changing of the fiber content (0.1-0.7 wt%). An electrodeposition process was used to produce Cu-coated SCFs. To investigate the effect of Cu-coated SCFs on the composite mechanical and electrical properties, we prepared two kinds of reinforcements:SCFs treated by 400 oC (400 oC-treated SCFs) and Cu-coated SCFs (Cu-SCFs). Fracture characteristics of the composites revealed that the Cu coating and the epoxy matrix had a better interface, meaning that the tensile and bending strength results were better in epoxy/Cu-SCFs composites than those in epoxy/400 oC-treated SCFs composites. The 400 oC-treated SCFs decreased the electrical resistivity of the epoxy composites compared to the pure epoxy. However the epoxy/Cu-SCFs composites had lower electrical resistivity than epoxy/400 oC-treated SCFs with the same fiber content.

      • KCI등재

        Enhancing Tensile Properties of Wire-Arc Additively Manufactured Ti-6Al-4 V Deposits Via Cryogenic Vaporised Ar Shielding/Cooling

        Peng Han,Jia Lin,Wen Wang,Zhihao Liu,Yating Xiang,Ting Zhang,Qiang Liu,Xiaohu Guan,Ke Qiao,Yingchun Xie,Kuaishe Wang 대한금속ᆞ재료학회 2023 METALS AND MATERIALS International Vol.29 No.2

        The high-entropy alloy particles reinforced 6061Al composite was prepared by cold spray (CS) and then modified by frictionstir processing (FSP). The microstructure evolutions, corrosion, and wear behaviors of the composites were investigated. Results showed that numerous micro-pores and cracks were distributed in the Al matrix due to adiabatic shear instability andinsufficient deformation of the deposited particles for CSed samples. The average size of uniformly distributed HEA particleswas ~ 24 μm, and the geometric necessary dislocation (GND) density reached 17.1 × 1015m−2 due to large plastic deformationduring CS. Comparatively, the micro-pores and cracks were eliminated, and many fragmented HEA particles dispersed inthe Al matrix with an average size of ~ 4 μm for FSPed sample. Note that the GND density reduced to 9.8 × 1015m−2 due todynamic recrystallization during FSP. The formation rate of the oxide film was gradually greater than that of the dissolutionrate with the samples immersion in 3.5 wt% NaCl solution from 12 to 36 h, and the main corrosion mechanism was particledissolution around micro-pores and pitting for CSed and FSPed samples, respectively. In the polarization process, the FSPedsamples exhibited low corrosion tendency and high corrosion rate due to the dense and uniform microstructure, low GNDdensity, and dispersed HEA particles. The FSPed samples had better wear resistance than the CSed samples at 25 °C and200 °C. The dominant wear mechanisms of CSed and FSPed samples were abrasion at 25 °C, while the wear mechanismsof these samples were adhesion accompanied by abrasion at 200 °C.

      • AN ANALYSIS AND RESEARCH OF ROUTING PROTOCOL FOR MANET

        Lejun Chi,Zhongxiao Hao,Chunlong Yao,Yating Zhang,Kun Wang,Yang Liu 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-

        In typical methods for accessing Internet or intranet in mobile wireless environment, users can access to fixed networks without multi-relay based on Broad Band access networks. Especially in some special applications, messages from source users can only arrive at destination terminals by multi-relay among several mobile users because wireless network is infrastructural, which is so called Ad hoc networks. There are many up-to-date research results in table driven routing and on-demand routing for ad hoc mobile networks are proposed in this paper. In the mentioned two kinds of routing protocols, DSR and DSDV, this paper not only introduces the contents of the routing protocol, but also points out their advantages and drawbacks, and evaluates these protocols based on a given set of parameters such as deliverance, end-to-end-delay, meanhop and load. This paper also evaluates some drawbacks of above routing protocols. Finally, the authors suggest the research direction in routing for ad hoc mobile wireless networks in the future

      • KCI등재

        A Preoperative Nomogram for Predicting Chemoresistance to Neoadjuvant Chemotherapy in Patients with Locally Advanced Cervical Squamous Carcinoma Treated with Radical Hysterectomy

        Zhengjie Ou,Dan Zhao,Bin Li,Yating Wang,Shuanghuan Liu,Yanan Zhang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.1

        Purpose This study aimed to investigate the factors associated with chemoresistance to neoadjuvant chemotherapy (NACT) followed by radical hysterectomy (RH) and construct a nomogram to predict the chemoresistance in patients with locally advanced cervical squamous carcinoma (LACSC). Materials and Methods This retrospective study included 516 patients with International Federation of Gynecology and Obstetrics (2003) stage IB2 and IIA2 cervical cancer treated with NACT and RH between 2007 and 2017. Clinicopathologic data were collected, and patients were assigned to training (n=381) and validation (n=135) sets. Univariate and multivariate analyses were performed to analyze factors associated with chemoresistance to NACT. A nomogram was built using the multivariate logistic regression analysis results. We evaluated the discriminative ability and accuracy of the model using a concordance index and a calibration curve. The predictive probability of chemoresistance to NACT was defined as > 34%. Results Multivariate analysis confirmed menopausal status, clinical tumor diameter, serum squamous cell carcinoma antigen level, and parametrial invasion on magnetic resonance imaging before treatment as independent prognostic factors associated with chemoresistance to NACT. The concordance indices of the nomogram for training and validation sets were 0.861 (95% confidence interval [CI], 0.822 to 0.900) and 0.807 (95% CI, 0.807 to 0.888), respectively. Calibration plots revealed a good fit between the model-predicted probabilities and actual probabilities (Hosmer-Lemeshow test, p=0.597). Furthermore, grouping based on the nomogram was associated with progression-free survival. Conclusion We developed a nomogram for predicting chemoresistance in LACSC patients treated with RH. This nomogram can help physicians make clinical decisions regarding primary management and postoperative follow-up of the patients.

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