에어리프트 펌프를 이용한 정밀여과막 세척

이준호,김명호,고대현 韓國交通大學校 2022 한국교통대학교 논문집 Vol.57 No.-

The MBR method, also known as the membrane separation active sludge method, does not require a precipitation tank and has many advantages such as stable discharging water. The biggest disadvantages of the MBR method, which has many advantages, are maintenance problems due to reduced flux due to fouling, decreased processing efficiency, and membrane replacement. In this study, in order to reduce membrane pollution, membrane cleaning was performed using the washing principle of the airlift pump, and shear force according to the amount of air was analyzed using the Ansys Fluent computational fluid dynamics program. As a result of the analysis, the film recovery rate was 93.8% to 97.3% and the average was 95.8%, and the CFD analysis showed the highest shear force at about 5.425×10-2Pa at 10m3/m2/hr. It is believed that the MBR device using Airlift in this study can maximize the flux recovery rate by reducing the problem of membrane contamination.

정신분열병 환자에서 Risperidone에 의한 Cytokine의 변화

김대진,김원,윤수정,고효진,최보문,전태연 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

기존의 항정신병약뮬인 haloperidol이나 clozapine과는 약물학적 특성이 다른 대표적인 약물인 risperidone을 사용하여 정신분열병 환자가 치료 전과 4주 치료 후에 어떤 면역학적 차이를 보이는지 6가지 cytokine의 혈장 농도를 측정하여 알아보았다. 방법: 1999년 2월부터 1999년 5월까지 카톨릭대학교 대전성모병원 정신과에 입원한 환자 중 DSM-IV 진단 기준에 의해 정신분열병으로 진단된 환자 25명을 대상으로 하였다. 입원 다음날 아침 8시 risperidone 투여전의 기본적인 cytokine농도를 측정하기 위해 혈액을 채취하였으며 제 2병일에 risperidone 2mg, 제 4병일에 4mg, 제 6병일에 6mg으로 증량하는 방식을 항정신병약물 치료를 하였다. 임상평가는 risperidone 투여 전과 투여 4주 후 정신과 전공의가 각각 PANSS 검사를 시행하였다. 혈장에서 IL-1β,IL-2, IL-6, IL-12, INF-□, TNF-α의 정량 측정은 ELISA kit (Endogen Inc., Woburn, MA, USA)을 사용하여 quantitative ELISA법으로 하였다. 결과: risperidone을 4주간 투여 후 환자 혈장 IL-12 농도가 유의하게 증가되었고 나머지 cytokine 농도는 유의한 변화가 없었다. 결론: 저자들은 연구에서 risperidone 치료 후 IL-12가 증가된 것은 이러한 항정신병약물치료가 면역반응 을 활성화시키는 역할을 한 것으로 시사된다. Objectives: This study was carried out to evaluate immunologic difference between baseline and after 4 weeks drug treatment with atypical antipsychotics(rispreidone) by measurement of serum concentration of 6 cytokines. Methods: The subjets were composed of 25 patients who are admitted at Dajeon St's Marys hospital of psychiatry department and diagnosed as schizophrenia by DSM-IV diagnositc criteria. We measured serum IL-1β, IL-2, IL-6, IL-12, INF-□, TNF-α concenatrations by quantitative ELISA method using ELISA kit(Endogen In., Woburn, MA, USA). The two psyciatrists per-formed PANSS examination between baseline and after 4 weeks risperidone treatments. Results: The serum level of IL-12 was increased significantly after medication of 4 weeks and the serum concentration of IFN-□ showed the tendency of decreasement but not significant. The serum level of the other cytokines showed no significant change. Conclusion: We spectulate that the increasement of IL-12 may contribute to role of activa-tion of immune response by treatment of antipsychotic medication(risperidone). This study is first trial of IL-12 study in neuropsychiatric field and IL-12 which play impor-tant role of immune response becomes interesting subjects in immune research.

현행초과이익과 EVA를 이용한 가치평가모형의 실증비교

이대선,박성환,윤준재 서강대학교 경영연구소 2005 서강경영논총 Vol.16 No.1

양측성 다낭종신 태아의 중반기 중절 1례

손대언,송창훈,한세준,이미자,기근홍 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Recently, the use of Ultrasonography as a diagnostic method in detection of fetalanomalies during pregnancy has been increased because of the safety. Many fetal genitourinary anomalies were reported as early as mid trimester by transabdomonal sonography. We experienced a case of bilateral polycystic kidney in 23th months gestatational aged fetus, diagnosed by transabdominal ultrasonography and pathologic authopsy.

소아 대퇴 간부 골절의 장기 추시 결과

신현대,양준영 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

Femoral shaft fractures in children remain a common but interesting subject of pediatric trauma. The management of these fractures gradually has evolved toward a more operative approach in the past decade. But their treatment by age has become widely accepted. In children younger than 4 years, spica casting has found to render excellent long-term results. For the age group older than 10 years, spica cast are being used with intramedullary fixation. However, for the age group between 4 years and 10 years, no consensus has been found. We reviewed of treatment of the femoral shaft fractures in 27 children age 4 to 10 years between July 1988 and October 1996. Fifteen were treated with early spica casting, the others with flexible intramedullary nails. No nonunions or significant malunion were seen. But patients treated with flexible intramedullary nails were able to do early partial weight bearing and had less immobilization period. Flexible intramedullary nailing of femoral shaft fractures in 4 to 10-year old age group seems to he safeand effective method and may be the treatment of choice.

Coagulant와 Hydro-cyclone을 결합한 상향류식 여과시스템

김명호,고대현,정다래,이준호 한국교통대학교 2021 한국교통대학교 논문집 Vol.56 No.-

Coagulation Hydro-cyclone can be added to the upward flow filtration system utilizing Fiber-Ball filter media to analyze and evaluate the treatment characteristics in order to Non-point pollution, which is a pollution problem, more efficiently. Hydro-cyclone was added to the existing Filter column to create an Up-Flow Filtration system. The treatment efficiency according to the operating conditions such as turbidity, suspended solids, pH, inflow flow rate, and head loss was analyzed. Comparison of inflow water and runoff water suspended solids and turbidity analysis results showed a minimum treatment efficiency of 93.21% and a maximum treatment efficiency of 99% or more. It was analyzed that the SS and turbidity analysis results showed a treatment efficiency of 80% or more before and after backwashing twice. When Coagulation Hydro-cyclone was added compared to the existing filtration system, it was analyzed that particles that had not been treated as an adsorption fiber company filter medium between particles could be treated.

BTT 미사일의 상태변수 추정 및 자동조종장치의 구현

송용규,전대길 한국항공대학교 1999 論文集 Vol.37 No.-

본 연구에서는 신경망 상태변수 추정기에 기반한 BTT 미사일 자동조종장치의 구현을 고려한다. 여기에서 고려되는 BTT 미사일은 실제적인 비선형성을 포함하고 있다. 자동조종장치를 구현하기 위해 먼저 신경망 기법을 이용하여 상태변수 추정기와 부분선형화 제어기를 설계하고 이들의 성능을 평가하기 위해 제어기등 모든 요소가 포함된 전체 궤환루프를 수치적으로 모의 실험한다. 또한 수치 모의 실험은 강건성을 평가하기 위해 공기역학적 불확실성이 존재할 경우에도 수행한다. In this work an implementation of a neural network state estimator-based autopilot for BTT missiles is considered. The considered BTT missile model comprises rather practical nonlinearities. To implement the autopilot, a state estimator and a partial linearizing controller are designed via neural network techniques. Furthermore, the complete closed-loop system containing all components is simulated in order to evaluate the performance of the estimator and the partial linearizing controller. The simulations are also performed under some aerodynamic uncertainties to see the robustness of the closed-loop system.

Risperidone 조기 중단군 및 장기 유지군의 임상적 특성 비교

김광수,박원명,전태연,배치운,김대진,백인호,이철,김정수,한상익,최보문,장계호,고효진 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : Risperidone 투여후 조기 중단한 환자들과 장기적으로 계속 risperidone을 복용하고 있는 환자의 임상적 특성을 평가하고 나아가 risperidone장기 유지와 조기 중단의 요인을 분석하고 정신병리가 약물 투여에 미치는 영향을 조사하고자 하였다. 방 법 : 연구 대상자는 1996년 1월부터 1996년 12월까지 가톨릭대학교 의과대학 부속 8개 병원 정신과에서 risperidone을 투여 시작한 환자 580명중 DSM-IV기준에 의해 정신분열병으로 진단받고 투여 기간이 6개월 미만(조기 중단군)이거나 2년 이상(장기 유지군)을 경과하였으며 의무기록의 누락이 없는 210명을 선정하였다. 두 군간 임상적 특성을 조사하기 위하여 인구학적 변인, 정신병리학적 변인, 약물 투여기록 및 부작용 등을 과거 의무기록을 근거로 평가하였다. 결 과 : 대상환자 210명 중 조기 중단군이 67명(31.9%)이었고 장기 유지군은 143명(68.1%)이었으며 두 군간 인구학적 변인과 정신병리학적 변인에 따른 특징에는 두 군간 차이가 없었다. 두 군간 risperidone의 시작 용량과 변인과 정신병리학적 변인에 따른 특징에는 두 군간 차이가 없었다. 두 군간 risperidone의 시작 용량과 최대 용량은 유의한 차이가 없었으나 유지용량은 조기 중단군에서 4.49(±1.44)mg,장기 유지군에서 3.67(±1.50)mg으로 유의한 차이가 있었다(t=3.698, p<0.05). 또한, 이전 항정신병약물의 사용 기왕력 변인에서 조기 중단군은 기왕력이 없는 환자가 39명(58.2%), 고역가 항정신병약물을 사용한 기왕력이 있는 환자는 27명(40.3%), 저역가 항정신병약물을 사용한 기왕력이 있는 환자는 1명(1.5%)이었고, 장기 유지군은 기왕력이 없는 환자가 58명(40.6%), 고역가 항정신병약물을 사용한 기왕력이 있는 환자는 77명(53.8%), 저역가 항정신병약물을 사용한 기왕력이 있는 환자는 8명(5.6%)으로 유의한 차이가 있었다.(x²=6.559, df-=2, p<0.05). 결 론 : 본 연구결과에 의하면 가급적 환자 상태에 따라 낮은 최적 치료 용량을 투여하는 것이 장기잔의 투여를 바람직한 것으로 생각된다. 본 연구와 같은 대규모의 후향적 자연적 연구는 일반 실제 진료에서 risperidone의 효과 및 기타 다른 측면에서의 유용한 정보를 얻을 것으로 기대된다. Objective : This retrospective naturalistic study was designed to compare the clinical characteristics including psychopathology of two groups of patients, long-term maintenance group and short-term drop-out group, who were taking risperidone. Method : Datas were collected for 210 schizophrenic patients with complete medical records among 580 patients who were enrolled with risperidone administration from January 1996 to December 1996 in 8 affiliated hospital of the Catholic University. The short-term drop-out patients group were assigned to whom treatment period was less than 6 month, and the long-term maintained patients group, treatment period was more than 2 years. We assessed demographics, psychopathology, and other variables related with medication based on past medical records. Results : Among subjects of 210, short-term drop-out patients group were 67(31.9%) and long-term maintained patients group were 143(68.1%). Demographics and psychopathology were not significantly different between two groups. The stating and maximal dosage of risperidone was not significantly different between two groups but the maintenance dosage of risperidone was lower in long-term medicated patients group than short-term drop-out patients group(t=3.698, p<0.05). Additionally, the result of this study showed differences in experiences of past antipsychotic use as following. The number of no previous use of antipsychotic was 39(58.2%), the number of high potency amtipsychotic use was 27(40.3%), and the number of no previous use of antipsychotic was 58(40.6%), the number of high potency ntipsychotic use was 77(53.8%), the number of low potency antipsychotic use was8(5.6%) in long-term maintained group.(x²=6.559, df-=2, p<0.05). Conclusions : According to these results, administration of low therapeutic dosage should be recommended for long-term maintenance as if possible. Multi-center based retrospective naturalistic study like this would be useful for getting informations about efficacy and some other aspects of antipsychotic administration in practial field.

C^(60)_(0)γ線으로 照射된 低密度폴리에틸렌에서 脫氣體試科와 非脫氣體試科의 트리이 現象의 比較硏究

金正洙,吳成基,田大守 弘益大學校 1987 弘大論叢 Vol.19 No.2

Low density polyethylene was irradiated respectively with 5, 15, 20, 50, 80[Mrad] by C^(60)_(0)γ ray. And the irradiated specimens remained at the air naturally for one year. And part of those specimen was again degassed at the Vacuum of 10^(-3)~10^(-4)[Torr] for 50,100[h], at 50℃ And we abserved comparatively the length of tree growth and the number of cumulative discharge at the constant voltage and temperature of 7.5[KV] and 20[°C] about those degassed and other non-degassed specimen. At the result there was not much difference of the breakdown time of tree length between degassed and non-degassed samples at 5, 15 and 20[Mrad], but the breakdown time of degassed samples became longer than the of non-degassed ones at 50. 80[Mrad]. And the number of cumulitive discharge pulsed became predominantly few at degassed samples. And this fact was intepreted that the gas in samples came out in degassing and the gas pressure of tree path became decreased and the bigining voltage of discharge became high due to the region of low pressure in Paschen's law and the occurrence frequency of partial discharge decreased. And we could be confirm that the result of experiment and the theory are wonderfully coincidend each other.

악교정 수술중 수액요법과 술후 합병증의 연관성

류정호,김대윤,배준수,양병은,유준영,김용관 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.5

Few topics in operative and perioperative patient management generate more controversy than that of appropriate fluid and electrolyte therapy. especially, controversy has swirled around colloid vs crystalloid therapy and the composition of administered fluids, agreement among clinicians as to what fluid therapy is appropriate, and in what amount, is rare. This controversy likely will be enhanced by Arieff' s provocative article. He described 11 adults and 2 pediatric patients. All developed fatal postoperative pulmonary edema, seemingly caused solely by excessive postoperative fluid administration. From January 1999 to December 1999, we investigated 24 patients, which were operated by orthognathic surgery, about the intraoperative fluid therapy and the associated effect in orthognathic surgery, which is regarded as one of the major surgery of oral and maxillofacial surgery. First, They were devided into two groups, that is one-jaw surgery and two-jaw surgery, and each groups were devided by intraoperative fluid volume of 8ml/kg/hr. Subjective assesment was collected through use of a series of 3 questionnaries. In each questionnaire, a 5-point Liekert scale was used far assessment of following parameters of recovery from anesthesia: headache, dizziness, drowsiness, nausea/vomiting, thirst. The patient completed questionnaire 1 at 4 hour after surgery, questionnaire 2 was completed at 24 hours after surgery, and questionnaire 3 was completed at 48 hours after surgery. This study demonstrated that appropriated perioperative rehydration decreases postoperative adverse outcomes and improved the patient's perception of the postoperative period.