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송창훈,배홍진,함영록,나기량,이강욱,최대은 전해질고혈압연구회 2017 Electrolytes & Blood Pressure Vol.15 No.2
Ethylene glycol is a widely used and readily available substance. Ethylene glycol ingestion does not cause direct toxicity; however, its metabolites are highly toxic and can be fatal even in trace amounts. Poisoning is best diagnosed through inquiry, but as an impaired state of consciousness is observed in most cases, poisoning must be suspected when a significantly elevated osmolar gap or high anion gap metabolic acidosis is found in blood tests. Hemodialysis and alcohol dehydrogenase inhibitors such as ethanol and fomepizole are a part of the basic treatment, and timely diagnosis and treatment are crucial because any delays can lead to death. However, there are few reported cases in Korea, and no report on the use of fomepizole. Herein, we report a case of acute renal failure caused by ethylene glycol poisoning that was treated with fomepizole and hemodialysis and present a literature review.
소형디젤엔진용 E-EGR 밸브의 개발 및 차량적용에 관한 실험적 연구
송창훈,정용일,차경옥 한국에너지학회 2002 에너지공학 Vol.11 No.3
본 연구에서는 유니크에서 개발된 E-EGR 밸브의 특성을 분석하였으며, 차량적용의 가능성을 평가하였다. 메르세데스 벤츠에서 개발된 배기량 0.8리터급 소형디젤 승용차인 Smart cat가 본 실험에 사용되어졌다. 실험용 차량은 전자식 EGR 밸브가 장착된 3기통의 터보 과급식 차량이다. 테스트벤치에서 EGR 밸브의 성능을 비교 및 분석한 후 차대동력계상에서 EGR map과 CVS-75 시험결과를 통하여 전자식 EGR 밸브의 차량적용 가능성을 여부를 수행하였다. In this study the characteristics of E-EGR valve developed by Unick were analyzed and the feasibility of application to vehicles were evaluated. Smart car (3$\ell$/100 km) and engine which is small-displacement size, 0.8-liter, of diesel passenger car developed from Mercedes-Benz were used for this experiment. It was installed a 3-cylinder turbo-charged light duty diesel engine with an electronic EGR valve. After the analysis and comparison of E-EGR valve performance under test benches, the estimation of vehicle application was executed through the EGR map and CVS-75 test result measured on the chassis dynamometer.
의과대학 산과학 강의에 있어서 주제발표식 학습에 시도와 문제점 분석
송창훈 朝鮮大學校 附設 醫學硏究所 1998 The Medical Journal of Chosun University Vol.23 No.1
Traditionally, medical education was performed by professor-centered lectures However, medical education is changing rapidly from traditional concepts to new trends. One of the changes is problem based learning. The purpose of this study is to model the modified PBL which is adjusted in our educational environment. A class of 165 students at Chosun U-niversity Medical School. was selected as a study group from August 1997 to October 1997. The lecture was performed by the students themselves every week according to lecture topics given from the tutor. The results were as follows: 1.The students' own opinions about ; ubject-Oriented Student Lecture(SOSL) were mainly(78%) that it was worthy of development with repletion. 2. The students who wanted to partici late in a lecture were 58.8%, and the students who didn't want were 38%. 3. The disadvantages of SOSL, which were indicated by students, were disorganized and disarranged lectures(31.9%), unclear lectures(30%), lack of reliability (19.4%), and partial participation(18.8%). 4. The students who participated in SOSL needed additional professor's supplementary lecture(54.3%), whole participation (48.9%), presentation skills (40%), programming (24%). preparation (17%). 5. The students had difficulty in group study (60%), subject understanding (446%). reference survey(31%),and lack of time(26%). 6. The educational patterns of Chosun Medical School were professors-entered with lecture notes (79.4%). 7. The students that wanted changes from the previous teaching methods were 96.9% and those that did not want changes were 3.1%. In conclusion, SOSL may cause some confusion and dissatisfactions to students who are familiar with traditional professors-entered lectures, but by revolution and development. SOSL will be applicated as an effective instruction in our actual circumstances.
4행정 가솔린기관의 상용배기시스템 소음저감 및 성능에 관한 실험적연구
송창훈,양진승,차경옥 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-
In vehicle exhaust systems the sound attenuation and the reduction of flow losses are often two competing demands. The present study considers a fully vehicle exhaust system and investigates experimentally both the sound attenuation and the flow performance of production configurations including the catalyst, the resonator, and the muffler. Dynamometer experiments have been conducted with 1500cc engine with speeds ranging from 1000 to 5000 rpm. Measurements include the flow rates, the temperatures and the absolute dynamic pressures of the hot exhaust gases at point locations. The present study describes the experimental aspects of an ongoing effort to validate and use the nonlinear fluid dynamic models in the time-domain for the prediction of the acoustic and power performance of firing internal combustion engines with full production exhaust systems.
동맥-정맥 우회술을 이용한 염소 태자의 태반 기능 보조법에 관한 연구
송창훈,이국현,박석천,소금영,김지애,장철호 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.1
Background : The extrauterine fetal incubation system must meet stable blood gas exchange and sufficient oxygen supply to provide the physiologic oxygen consumption of the fetus. In the fetus, blood gas exchange is totally sustained by the placental circulation. The placenta can be regarded as an extracorporeal organ, and the basic structure of placental circulation comprises arteriovenous (AV) bypass. To mimic this mode of circulation, we used AV ECMO (extracorporeal membraned oxygenation) in the goat fetus, and attempted to achieve stable blood gas exchange and oxygen supply to the fetus. Methods : Pregnant goats, weighting 30-35 ㎏, were anesthetized with N_2O-O_2-enflurane. We performed a cesarean section with a midline incision, and cannulated via the umbilical vessels after a hysterotomy, and connected the fetuses to an ECMO circuit. The fetus was transferred to an incubator containing normal saline mixed with antibiotics. Blood samples were obtained every 4 to 6 hours from the circuit for electrolytes, hemoglobin and blood gas analysis and arterial blood pressure and heart rate were monitored through the umbilical artery. Oxygen delivery and consumption were calculated from the measured parameters. Microscopic examinations of the liver, kidney and lung were performed 24 hours after ECMO to know the effect of AV ECMO on the circulation of the organ. Results : AV ECMO was done for 24 hours in the six goat fetuses and the main cause of death was circulatory failure. Heart rates and blood pressure were stable during ECMO. Sodium bicarbonate was injected when mild acidosis occurred and blood gas exchange was maintained stable. Mean pump flow rate was 156 ± 62 ml/min/㎏ and oxygen extraction ratio was 30.4%. The liver function tests were sustained within normal limits both before and 24 hours after ECMO, but BUN and creatinin increased beyond upper normal limits 24 hours after ECMO. Microscopic features of the liver and kidney showed congestion 24 hours after ECMO. The fetal lung after 24 hours of ECMO especially showed an increase of mature capilllaries in the septum and wall of alveoli compared with the twin fetal lung. Conclusions : These results indicate that the extrauterine fetal incubation model used for this study was suitable to blood gas exchange and utility of oxygen for goat fetuses. (Korean J Anesthesiol 2002; 42: 95~106)