사후분해 시체에 대한 법의학적 접근

최영식,이상용,김유훈,조갑래,이봉우,양경무,정낙은,서중석,이한영,이원태,강현욱 大韓法醫學會 2000 대한법의학회지 Vol.24 No.2

Disposal of a homicide victim by dismemberment is rare, but individual cases are on record in most major medicolegal departments. Recognition of postmortem mutilation may be of importance in the interpretation of certain murders committed by sexual perverts and other mentally deranged individuals and sometimes performed for the sole reason of easier disposal of the body. Postmortem dismemberment is usually readily recognizable as such; The edges of the injuries are dry and lack evidence of bleeding. The joints may be disarticulated without fracture, or the use of an axe or saw may be evident from examination of bones. Parallel horizontal or oblique furrows in the bone surface are caused by skipping of the saw prior to establishing depth. Such patterns on the bone may assist in identifying the particular saw involved. So we report 25 dismembered corpses that autopsied in National Institute of Scientific Investigation. This paper can help in attempting to establish not only the first criminal investigation steps but also the medicolegal approach methods in unidentified and dismembered deaths.

Hexachlorocyclohexane에 의한 肝細胞 傷害機轉과 Glutathione의 影響에 關한 超微細形態學的 硏究

李元基,黃一愚,孫泰重 慶北大學校 醫科大學 1980 慶北醫大誌 Vol.21 No.1

저자는 HCH투여로 인한 간세포의 변화를 알아보고 또 이에 대한 glutathione의 방어 효과를 알기 위하여 생쥐에 0.15%의 HCH을 1일 1회 0.1㎖, 0.2㎖를 단독으로 혹은 glutathion과 같이 7일간 투여한 후 형태학적으로 검색한 소견을 요약하면 다음과 같다. 광학현미경 소견으로는 간세포의 위축, 핵내의 공포화, 핵농축 및 핵소실등을 특징으로 하는 가역성 및 비가역성변화가 주로 간소엽의 중심대에 나타나며 이들 변화는 투여량이 많으면 다소 현저하여지고 glutathione을 같이 투여한 군이나 그렇지 않는 군과의 사이에는 차이가 없었다. 전자현미경 소견으로는 핵에 있어서는 핵 윤곽의 불규칙, heterochromatin의 증가, 핵소체의 위축, nucleolonema의 소실등 핵의 기능저하를 나타내는 소견이 주로 나타나고 분비기능과 관련되는 구조물에 있어서는 그 기능의 저하를 나다내는 rER의 감소, ribosome의 탈락, Golgi장치의 위축 및 그 내강의 VLDLP의 소실등의 현상이 나타나고 sER의 증식, glycogen 과립의 감소 내지 소실, cristae의 증가를 동반하는 mitochondria의 변형 내지 거대화, 그리고 microbody의 증가등 간세포의 해독 기능과 관련되는 구조물에 있어서는 기능항진 현상이 나타나고 그밖에 퇴행성변화로서 Cristae의 감소 내지 소실을 동반하는 mitochondria의 팽화, 세장화 및 거대화, 각종 lysosome의 증가, lipid droplet의 증가등이 나타나고 Kupffer 세포에서는 탐식능의 항진을 나타내는 현상으로 생각되는 phagosome이 심히 증가하였고 보통의 경우 관찰할 수 없는 3층 구조물이 mitochondria 내에서 관찰되었다. 이상의 소견으로 보아 HCH를 투여하면 간에 있어서 두가지의 현상이 한세포내에 같이 혹은 별도로 출현한다. 즉 HCH로 인한 간세포 상해현상으로서는 핵의 위축, cristae의 감소 내지 소실을 동반하는 mitochondria의 팽화, 세장화 및 거대화, 각종 lysosome의 출현, rER의 수포화 및 감소, rER의 ribosome의 탈락등이 일어나고 HCH를 해독하기 위한 현상으로서는 sER의 증식, glycogen 과립의 감소, cristae 증가를 동반하는 mitochondria의 변형 및 거대화, microbody의 증가등이 일어나며, 이들 변화는 투여량이 많으면 더 증가하고 glutathione의 병용투여로서 그 변화가 다소 경감되는 경향이라 생각된다. 그리고 mitochondria에서 관찰된 간 세포에서는 볼 수 없는 층상구조물에 대해서는 앞으로 더 관찰할 흥미있는 것이라 믿어진다. It is a well known fact that hexachlorocyclohexane (HCH) remains unexcreted in the liver cells and extend toxic effect to them, but the mechanism is not understood in detail. This study was carried out in an attempt to investigate the mechanism of toxic effect of HCH on liver cells by examining the ultrastructural alterations after HCH administration and also glutathione was added to HCH to see if it has any protective effect to the hepatocyte damage. Thirty-four experimental mouse weighing about 30gm were divided into 3 groups: group I was given 0.1㎖ of HCH to 3 mice and 0.2㎖ to 3 mice intramuscularly daily for 7 days, group 2 20mg of glutathione added and group 3 only the solvent, olive oil, as a control. The animals were sacrified on day 8 and on day 10. The results were summarized as follow: On light microscopic examination the liver cells revealed atrophy, intranuclear vacuolization, pyknosis and karyolysis. These changes were particulary prominent in the centrilobular zones, and were more severe in the group treated with high dosage, but no evidence of protective effect of glutathione was noted. Electron microscopically, nuclei showed irregularity of nuclear contour, increase of heterochromatin, and atrophy and loss of nucleolonema of nucleoli, Secretory organelles, showed decrease of rER, shedding of ribosome, and atrophy and loss of VLDLP in Golgi apparatus suggesting functional derangement. On the other hand, changes of organelles involved in detoxication suggested increased activity by revealing of proliferation of rER, decrease or loss of glycogen particles, distorted and enlarged mitochondria combined with increase of cristae and increase of microbody. Also degenerative changes were noted such as welling of mitochondria with decrease and loss of cristae, increase of primary and secondary lysosomes, and increase of lipid droplets. Kupffer cell showed increase of phagosome suggesting increased phagocytic activity. Thee results are suggesting that two different phenomena are occuring in the liver cells by HCH injection. The one was liver cell injury and the other was increased activity of organelles involved in detoxication. The severity of changes was more strong in higher dosage group. Administration of glutathione seemed to lessen the toxic effects of HCH in mild degree.

Gd₂O₃doped CeO₂의 미분말 합성 및 소결특성

이주신,김원중,박성용 경성대학교 공학기술연구소 1999 공학기술연구지 Vol.6 No.-

10mol% Gd₂O₃doped CeO₂ doped fine powders were synthesized by the oxalate coprecipitation method and then their powder characteristics and sintering behavior were studied. The characterization of powders has been investigated using thermogravimetry and differential thermal analysis for thermal analysis, X-ray diffraction for phase identification. Brunauer-Emmett-Teller, X-ray diffraction-line broadening and transmission electron microscopy for particle size and morphology determination. The sintering behavior were investigated by means of the sintering density measurements and scanning electron microscopy techniques. The characteristics of powders prepared by the oxalate coprecipitation method and their sintering behavior are discussed.

연속형 센서와 웨이브 전파를 이용한 판 구조물의 손상감지

이종원,최광호,이중원 남서울대학교 2007 남서울대학교 논문집 Vol.13 No.4

Abstract : The response characteristics of long continuous sensors are studied for damage detection in a plate structure based on strain waves that are generated by damage. That is, the response characteristics of the long continuous sensors, which are long ribbon-like sensors and can be fabricatedby piezoceramic ribbon fibers, etc. are studied by simulation of wavepropagation in a panel to improve sensing capability of the waves that arepropagating by damage. The advantage of the long continuous sensor is toimprove damage detection by having a large coverage of sensors on thestructure using a small number of channels of data acquisition. Theresponses from the long continuous sensor are similar if the damages arelocated at the same normal distance to the sensor, and these similar patternscan make it easy to estimate the damage. Keywords : long continuous sensor, damage detection, wave propagation 요지 : 이 연구에서는 손상에 의해 발생하는 변형률 웨이브 검출을 통한 판 구조물의 손상위치추정을 위하여 연속형 센서의 응답특성에 대하여 연구하였다. 즉, 균열발생 및 균열진전등과 같은 손상에 의하여 발생되는 웨이브를 보다 효과적으로 감지하기 위하여, 피에조 세라믹 섬유 등을 이용하여 리본 형으로 길게 제작할 수 있는 연속형 센서의 응답특성을 웨이브 전파 시뮬레이션을 통하여 연구하였다. 이러한 센서를 적용하는 경우, 적은 수의 데이터 취득 채널을 이용하여 구조물의 넓은 영역을 감지할 수 있는 장점이 있다. 또한 연속형 센서와 여러 손상위치들의 직각거리가 같은 경우 센서에서 감지되는 각각의 응답들은손상위치들에 대해 거의 동일한 양상을 보이며, 이러한 응답패턴을 이용하면 판 구조물의손상위치를 더욱 효과적으로 추정할 수 있을 것으로 판단된다. 핵심용어: 연속형 센서, 손상추정, 웨이브 전파

한국인 관상동맥의 변화양상에 대한 형태학적 연구

이상용,권태정,정낙은,서중석,이한영,이원태 大韓法醫學會 2002 대한법의학회지 Vol.26 No.1

ICT를 활용한 구성주의적 수업이 과학개념 획득과 문제해결에 미치는 효과

이춘희,정원우,김중욱,이윤종 慶北大學校 科學敎育硏究所 2004 科學敎育硏究誌 Vol.28 No.-

The purpose of this study is to examine in details the effects of the constructive instruction on the acquisition of scientific conceptions and the problem solving of Science based on ICT (Information and Communication Technology). In this study, An examination tool developed for a previous learning concept was applied to instructional model by a constructivism to students, and by grasping a previous learning concept and using ICT. An way of the improvement about acquisition of scientific conceptions and problem solving of subject was inspected, the rate of a correct answer, the decrease rate of misconception, and the achievement rate of a periodical examination were compared. The result of such enforcement was as follows; The motivational induction for learning, the interesting rate, and the rate of a correct answer in an experimental group showed highly. The result of a examination between an experimental group and a comparative group showed similarly. The rate of accomplishment also showed highly in an experimental group. Accordingly, the constructive instruction using ICT proved to be fit for seventh educational course as a student-centered course. The change of recompositional course for knowledge from a previous learning concept to a new one showed clearly.

현행 중학교 과학 실험·실습교육에 대한 교사들의 견해와 개선방안

이윤종,기우항,김영호,정원우,양승영,강용희,안병호,임성규,윤일희,김중욱,강동진 경북대학교 과학교육연구소 1996 科學敎育硏究誌 Vol.20 No.-

The status of facilities, management of the experiment, practices, and Science education teaching method in middle school have been investigated. The present status and reasonable management of middle school science education have been grasped from the questionaires. The results are as follows : The reasonable management for expeiments and practices of science education were scanty in the middle school around the urban and rural schools owing to the shortage of facilities and equipments, crowded class, excessive classes, work for teachers, excessive contents of present textbook and insufficience of administrative support etc. The current teaching method of middle school science has emphasized knowledge. This fact does not satisfy the objective of learning due to lack of teaching method. Desirable directions for the improvement of present status of middle school science education were proposed in this paper.

汗證의 時代的 傾向에 대한 文獻的 考察

李源中,辛祖永 한국전통의학연구소 2000 한국전통의학지 Vol.10 No.1

The results of about the sweet disease are as follows: 1. There had been knowledge of cause, steal-sweat, self-sweat, sweatless in Neiing(內經). 2. External causes were regarded as abnormal relationship of lung, weiqi(衛氣), and skin in excretion part, and internal causes were regarded as abnormal relationship of heart and kidney in metabolism. 3. The kinds of sweet disease were self-sweet, steal-sweat, and sweatless, there were head-sweat, heart-sweet, limb-sweat, axillary-sweat, and pubic-sweat in parts, and there were cutted-sweat, soft-sweat, blood-sweat, and yellow-sweat in types. 4. Prognosis of sweat disease were swellings of mouse and tongue and sweating as oil, and the men of head-sweat and severe coughing were regarded as immedicable. 5. The treatments of self-sweat were adding Yang(陽) and controling Wei(衛), and steal-sweat were adding Yin(陰) and downing Hua(火).

HBsAg양성 원발성간암에 있어서 HBV-DNA표지자의 PCR성적

이원길,김재식,김정철,서장수,강은자,이중원,김기연,송경은,양정선 慶北大學校 醫科大學 1997 慶北醫大誌 Vol.38 No.2

목적 : HBV-DNA를 정성적 그리고 정량적으로 검출함으로써 강한 전염성과 높은 유병율로 인해 사회적으로 문제가 되는 B형 간염과 원발성간암의 연관성을 알아보고자 하였다. 대상 및 방법 : B형 간염 표면항원(HBsAg)이 양성을 보이는 원발성간암 환자 38명을 대상으로 하였으며 HBV-DNA 중합효소연쇄반응법을 이용하여 정성적 검출 그리고 luminometry법을 이용하여 정량적 검출을 하였다. 결과 : HBV-DNA 중합효소연쇄반응법과 luminometry법의 양성율은 각각 57.9%, 39.5%를 보였다. 그리고 HBsAg과 HBeAg가 동시에 양성을 보인 11명에서는 HBV-DNA 양성율이 81.8%를 보였다. 결론: HBV-DNA 중합효소연쇄반응법의 양성율이 luminometry법에 의한 양성율보다 높은 결과를 보였고 HBV-DNA 검사는 B형 간염을 조기 발견하고 치료하여 만성간질환으로의 진행을 예방하고 특히 원발성간암의 병율을 낮추는데 많이 기여할 것으로 사료되었다. Background : Primary hepatocellular carcinoma(PHCC) is the most common malignant neoplasm in most countries of Asia and Africa. Hepatitis B virus is known to be strongly related to the pathogenesis of PHCC. HBV-DNA PCR and HBV-DNA quantitation assay were attempted to apply to 38 cases of HBsAg positive PHCC. Methods : The ordinary HBV markers(HBsAg, anti-HBs, anti-HBc(Ig-G and -M), HBeAg and anti-HBe) were examined with ELISA. Qualitative screening of HBV-DNA PCR and HBV-DNA quantitation-luminometric measurement were performed. Results : Among 38 cases of HBsAg positive PHCC, positive rates for HBV DNA-PCR and HBV DNA-quantitation were 57.9% and 39.5%, respectively. And 11 cases which were positive for both HBsAg and HBeAg showed 81.8% positive rate in HBV-DNA PCR. Conclusion : For 38 cases of HBsAg positive PHCC, the positive rate for HBV DNA-PCR was higher than HBV-DNA quantitation-luminometry. In HBV-DNA PCR, both HBsAg and HBeAg positive cases showed high positive rate.

모유수유에 영향을 미치는 요인 : 부산 지역 보건소 방문자에 대한 설문조사 연구

이현주,조영하,김원중 인제대학교 2010 仁濟論叢 Vol.25 No.1

The purpose of this study was to find out the status of breast-feeding practice, and to determine the factors affecting intention, practice and duration of breast-feeding for the mothers of babies, therefore contributing to provide effective measures for successful breast-feeding practice and further to promote breast- feeding practice. The data were collected from 200 mothers of babies less than 24 months old, visiting 4 health centers in Busan from February 23 to March 31, 2009 , and analyzed with Χ²-test, t-test, ANOVA, and logistic or multiple regressions by using SPSSWIN 13.0 program. The following results were obtained. First, the rate of practicing breast-feeding among mothers studied was 87.0%, and, however, the duration of breast-feeding was 6 months or less for more than half(51.7%). The most common reason for discontinuing breast-feeding was due to decreasing in milk volume with bottle-feeding and going through the weaning period for 21.3% each. Second, the degree of intent to breast-feeding during the pregnancy of the present baby was scored as 6.87 points out of 10 in total , and significantly higher in case of the first child and for the mothers not working. Third, regarding the factors affecting the practice of breast feeding, the rate of practicing breast-feeding was significantly higher in case of the first child and for the mothers with the past experience of breast-feeding. Forth, the duration of continuing breast-feeding became significantly longer as the intent to breast-feeding during the pregnancy was stronger. The above results suggested that pertinent measures should be deliberated to promote the duration of breast-feeding since the practicing rate for breast-feeding was apt to be high, and the duration to be short, however. It is urgent to prepare the measures to strengthen the intent to breast-feeding in order to promote the duration of breast-feeding, and especially to make efforts tprovide social and systematic ways to solve the problems facing in the real life for the working mothers to have the intent to breast-feeding, It also should be addressed to prepare publicity or education programs and effective measures for the women with the first child birth having intention to be able to practice breast-feeding.