임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

Antiallergic effect of fisetin on IgE-mediated mast cell activation <i>in vitro</i> and on passive cutaneous anaphylaxis (PCA)

Jo, Woo-Ri,Park, Hye-Jin Elsevier 2017 The Journal of nutritional biochemistry Vol.48 No.-

<P>Fisetin (3,7,3',4'-tetrahydroxyflavone), a naturally occurring bioactive flavonoid, has been shown to inhibit inflammation. However, little is known about the effect of fisetin on immunoglobulin E (IgE)-mediated allergic responses. In this study, the effect of fisetin on rat basophilic leukemia (RBL-2H3) cell-mediated allergic reactions was investigated. Fisetin inhibited beta-hexosaminidase release and decreased the level of interleukin-4 and tumor necrosis factor-alpha mRNA in IgE/antigen (IgE/Ag)-stimulated RBL-2H3 cells. To elucidate the antiallergic mechanism, we examined the levels of signaling molecules responsible for degranulation and release of inflammatory cytokines. Fisetin decreased the levels of activated spleen tyrosine kinase, Gab2 proteins, linker of activated T cells, extracellular signal-related kinase 1/2 in the IgE/Ag-stimulated RBL2H3 cells, and NF kappa B and STAT3 proteins activated in the ear tissue of mice with passive cutaneous anaphylaxis (PCA). In addition, fisetin significantly lowered of Fc epsilon RI alpha-subunit mRNA expression. Consistent with the cellular data, fisetin markedly suppressed RBL-2H3 cell-dependent PCA in IgE/Ag-sensitized mice. These results suggest that fisetin may have potential as a therapeutic agent for the treatment of allergic diseases. (C) 2017 Elsevier Inc. All rights reserved.</P>

Identification of electronic structure and structural phases in perovskite crystals

Hye Ri Jung(정혜리),Trang Thi Thu Nguyen,Hye-Jin Jin(진혜진),Bich Phuong Nguyen,Seokhyun Yoon(윤석현),William Jo(조윌렴),Won Seok Woo(우원석),Chang Won Ahn(안창원),Shinuk Cho(조신욱),Ill Won Kim(김일원) 한국신재생에너지학회 2017 한국신재생에너지학회 학술대회논문집 Vol.2017 No.9

Toward the Development of Introgressions Lines between Subspecies in Rice

Hye Ri Jo,Joong Hyoun Chin,Jung Hee Kim,Wen Zhu Jiang,Mi Ok Woo,Sang Ho Chu,Hee Jong Koh 한국육종학회 2005 한국육종학회 학술발표회 발표요지 Vol.37 No.1

증례 : 양수검사에서 AFP, AchE가 양성이였으나 정밀 초음파 추적검사 후 정상아를 분만한 1예

박혜리 ( Hye Ri Park ),전혜선 ( Hye Sun Jun ),차동현 ( Dong Hyun Cha ),박상원 ( Sang Won Park ),정창조 ( Chang Jo Chung ) 대한주산의학회 2006 大韓周産醫學會雜誌 Vol.17 No.4

신경관 결손증은 전세계적으로 약 1,000명당 1.4~2명의 발생빈도를 보이는 중요한 선천성 기형 중 하나로 알려져 있다. 선별검사(screening test)로서 모체혈청 AFP이 일반적으로 이용되고 있다. 그러나 이는 다태 임신, 태아 사망, 잘못 계산 된 임신주수, 낭성 임파관종, 기형종, 신장 이상, 식도 폐쇄증, 태반 이상 등 여러가지 경우에서 나타날 수 있으므로 일단 모체 혈청의 AFP이 증가되었다면 일단 임신주수, 태아의 생존여부, 태아의 수 등을 확신하기 위해서 우선 정밀 초음파 검사를 해야 하고, 이러한 경우를 제외한 후에 신경관 결손증이 의심되거나 확실하지 않은 경우 양수 내 AFP와 AchE를 측정한다. 그러나 양수 내 AFP은 위양성율이 높고, 이를 보완하기 위한 양수 내 AchE도 0.3%정도로 위양성율이 존재하므로 이때 정밀초음파에서 이상 소견 보이지 않을 때 과거력이나 유전력 등의 세밀한 상담 후 정기적인 정밀초음파 검사로 추적검사를 시행하면서 임신을 유지할 수 있다. 이에 본 저자는 임신 17주에 시행한 모체 혈청 AFP이 양성이 나와 시행한 양수 AFP, AchE이 양성이 나왔으나 시행한 정밀 초음파상 신경관, 복벽, 기타장기 내 기형 소견 보이지 않아, 가족력이나 과거력, 세밀한 유전력 상담 후 정기적인 정밀 초음파로 추적 검사하여 정상아를 분만한 한 1예를 보고 하는 바이다. Neural tube defects are reported one of the important congenital malformation in the world, with an incidence of 1.4 to 2 per 1000 pregnancies. Maternal serum AFP at the second trimester is used as screening test. But this is associated with numerous causes, including twins, fetal death, misdated pregnancies, cystic hygromas, teratomas, renal abnormalities, esophageal atresia and aberrations in the placenta. If the AFP level was elevated, targeted ultrasonography should be evaluated for confirming the gestational age and fetal viability, fetal number. Then if the ultrasonographic examination is nondiagnostic, or if an NTD is suspected, amniotic fluid AFP should be measured with acetylcholinesterase. But the false positive rate of the AF-AFP is high, and there is 0.3% of the false positive rate in amniotic acetylcholinesterase. This time the women with normal ultrasonographic examination continue the pregnancy after counseling of family history, past history with follow up of ultrasonography. We report a case with elevated second trimester MS-AFP, AF-AFP and positive amniotic acetylcholinesterase, but in which repeated sonographic findings were normal and result in delivery of a healthy baby without anomalies.

훈제오리에서 캠필로박터균 생물막 및 Viable But Non-Culturable(VBNC) 상태에서의 행동특성

조혜진(Hye Jin Jo),전혜리(Hye Ri Jeon),윤기선(Ki Sun Yoon) 한국식품영양과학회 2016 한국식품영양과학회지 Vol.45 No.7

본 연구에서 가금류의 주요 병원성 식중독 균을 인위적으로 오염시킨 훈제오리육을 진공포장 조건에서 10, 15, 24°C에 저장하면서 유통기한 동안 관찰한 미생물의 증식 및 생존 결과 Campylobacter jejuni는 저장기간 이내에 사멸하는 경향을 보였으며, Salmonella Typhimurium과 Listeria monocytogenes는 균주의 성장 속도에는 차이가 있었으나 증식하는 경향을 보였다. 훈제오리의 유통온도는 10°C이며 유통기한이 약 30일인 것을 고려했을 때, 초기 오염 수준이 Campylobacter 균주에 의한 식중독을 유발하게 되는 균수 500 CFU/g 수준 이하에서는 유통기한 내에 문제가 없을 것으로 생각한다. 그러나 낮은 온도에서 저항성이 증가하며 살아있으나 배양은 불가능한 상태인 VBNC 상태의 C. jejuni의 특성에 따라 적절한 조건에서 회복되어 병원성을 일으킬 가능성이 있으므로 C. jejuni에 대한 지속적인 관리가 필요하다. 또한, S. Typhimurium과 L. monocytogenes의 경우 일반적인 유통/보관 온도인 10°C에서도 증식이 가능하며, 특히 가공품 및 RTE 식품은 적절한 가열처리 없이 소비할 경우 식중독 발생 가능성이 높다는 점에서 제품 제조 단계에서부터 위생적인 관리가 필요하다. 본 연구에서는 C. jejuni biofilm cells을 인위적으로 오염시킨 훈제오리육을 진공포장 하여 일반 유통/보관 온도인 10°C와 실온, 그리고 일반적으로 C. jejuni가 증식 가능한 온도인 36°C에서 저장하였으나, C. jejuni biofilm cell은 훈제오리에서는 모든 온도에서 재증식이 불가능한 것으로 관찰되었다. 또한, 10°C의 저온에서 유도한 VBNC 상태의 C. jejuni를 훈제오리에 인위적으로 오염시키고 혐기적 조건에서 42°C에 1일간 저장하며 VBNC 상태의 C. jejuni의 재증식 가능성을 분석하였으나, 최적 증식 온도인 42°C에서도 재증식은 관찰되지 않았다. 이처럼 본 연구에서는 biofilm을 형성한 C. jejuni도 VBNC 상태의 C. jejuni는 살아 있으나 훈제오리에서의 증식은 관찰되지 않았다. 따라서 훈제오리에서의 C. jejuni의 위험성은 매우 적은 것으로 생각한다. 그러나 C. jejuni의 경우 매우 적은 양으로도 식중독을 일으킬 수 있고 C. jejuni biofilm 및 VBNC의 특성에 따라 잠재적인 위험성을 포함하는 동시에 유통/보관 온도인 냉장 온도에서 더 잘 살아남는다는 점에서 식중독 발생의 주요 원인으로 작용할 수 있는 교차오염과 전이를 예방하는 것이 중요하므로 이에 대한 관리가 강조되어야 할 것으로 생각한다. Biofilm cells and viable but non-culturable (VBNC) state may play a role in the survival of Campylobacter jejuni under unfavorable environmental conditions. The objective of this study was to investigate the behavior of C. jejuni biofilm cells and VBNC cells on smoked duck. The transfer of C. jejuni biofilm cells to smoked duck and its ability to resuscitate from biofilm and VBNC cells on smoked duck was investigated. Transfer experiments were conducted from C. jejuni biofilm cells to smoked duck after 5 min, 1 h, 3 h, and 24 h contact at room temperature, and the efficiency of transfer (EOT) was calculated. In addition, smoked duck was inoculated with C. jejuni biofilm and VBNC cells and then stored at 10, 24, 36, and 42°C to examine the cells" ability to resuscitate on smoked ducks. The 5 min contact time between C. jejuni biofilm cells and smoked duck showed a higher EOT (0.92) than the 24 h contact time (EOT=0.08), and the EOT decreased as contact time increased. Furthermore, C. jejuni biofilm cells on smoked duck were not recovered at 10, 24, and 36°C, and C. jejuni VBNC cells were not resuscitated at 42°C. Although the resuscitation of C. jejuni biofilm and VBNC cells was not observed on smoked duck, microbial criteria of C. jejuni is needed in poultry and processed poultry products due to risk of its survival and low infectious dose.

Optical and Scanning Probe Identification of Electronic Structure and Phases in CH₃NH₃PbBr₃ Crystal

Jung, Hye Ri,Kim, Gee Yeong,Nguyen, Bich Phuong,Jin, Hye-Jin,Jo, William,Thu Nguyen, Trang Thi,Yoon, Seokhyun,Woo, Won Seok,Ahn, Chang Won,Cho, Shinuk,Kim, Ill Won American Chemical Society 2017 The Journal of Physical Chemistry Part C Vol.121 No.40

<P>Hybrid lead halide perovskite possesses attractive properties and outstanding performance. The electronic structure of hybrid lead halide perovskite single crystal can be used to comprehend its intrinsic properties. In this study, the crystal structure of CH3NH3PbBr3 perovskite crystal was elucidated by transmission electron microscopy. Phonon modes and CH3NH3+ rocking modes were analyzed. Band gaps of the crystal were obtained by temperature-dependent Raman scattering spectroscopy and photoluminescence measurement. Surface potential measurement for a (001) plane exhibited a work function of the material and other phases of PbBr2 and CH3NH3Br. From experimentally determined values, an electronic structure of CH3NH3PbBr3 was built. It showed a p-type characteristic.</P>

Growth Characteristics of Glehnia littoralis Fr. Schmidt ex Miquel Grown under Various Light Intensity in a Closed-type Plant Production System

Hye Ri Lee,Hyeon Woo Jeong,Hyeon Gyu Jo,Su Min Kwon,Myung Min Oh,Seung Jae Hwang 한국원예학회 2020 한국원예학회 학술발표요지 Vol.2020 No.11

Enrichment Broth for the Detection of Campylobacter jejuni and Campylobacter coli in Fresh Produce and Poultry

Jo, Youmi,Oh, Hye-Min,Yoon, Yohan,Lee, Sun-Young,Ha, Ji-Hyoung,Kim, Won-Il,Kim, Hwang-Yong,Han, Sanghyun,Kim, Se-Ri ational Association for Food Protection 2017 Journal of food protection Vol. No.

<B>ABSTRACT</B><P>Although campylobacteriosis caused by Campylobacter jejuni and Campylobacter coli has been increasingly reported worldwide owing to the consumption of contaminated poultry and fresh produce, the current detection protocols are not selective enough to inhibit unspecific microbes other than these pathogens. Five antibiotics were separately added to Bolton broth, and the survival rates of 18 Campylobacter spp. and 79 non-Campylobacter spp. were evaluated. The survival rate of the non-Campylobacter spp. was the lowest in Bolton broth with rifampin (6.3%), followed by cefsulodin (12.7%), novobiocin (16.5%), and potassium tellurite and sulfamethozaxole (both 17.7%). Also the most effective concentration of rifampin was found to be 12.5 mg/L, which markedly inhibited non-Campylobacter strains while not affecting the survival of Campylobacter strains. After the Campylobacter spp. were enriched in Bolton broth supplemented with 12.5 mg/L rifampin (R-Bolton broth), CampyFood Agar (CFA) was found to be better in selectively isolating the pathogens in the enrichment broth than the International Organization for Standardization method of using modified charcoal cefoperazone deoxycholate agar (mCCDA) for this step. When applied to natural food samples-here, romaine lettuce, pepper, cherry tomato, Korean leek, and chicken-the R-Bolton broth-CFA combination decreased the number of false-positive results by 50.0, 4.2, 20.8, 50.0, and 94.4%, respectively, compared with the International Organization for Standardization method (Bolton broth-mCCDA combination). These results demonstrate that the combination of R-Bolton broth and CFA is more efficient in detecting C. jejuni and C. coli in poultry and fresh produce and thus should replace the Bolton broth-mCCDA combination.</P>

간세포암종에 대한 간동맥 화학색전술 후 발생한 급성호흡곤란증후군

조윤원,이정미,최자윤,유동훈,차라리,오혜원,김홍준,민현주,김현진,정운태,이옥재,하창윤,이선영 이화여자대학교 의과학연구소 2013 EMJ (Ewha medical journal) Vol.36 No.1

Transcatheter arterial chemoembolization (TACE) has become an effective alternative treatment strategy for patients with inoperable hepatocellular carcinoma (HCC). Although TACE is relatively safe, acute respiratory distress syndrome associated with pulmonary lipiodol embolism is a rare and potentially fatal complication. We report a rare case of acute respiratory distress syndrome after TACE for inoperable HCC. A 75-year-old man, with huge HCC in right lobe, was treated by TACE for the first time. Seven hours after uneventful TACE procedure, he felt dyspneic and his oxygen saturation recorded by pulse oximetry (SpO2) fell to 80% despite of applying non-rebreathing mask. He underwent mechanical ventilation with a protective ventilatory strategy. We experienced a case of acute respiratory distress syndrome after TACE for HCC.