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18–30세 사이에 발생하는 뇌경색의 특징, 다기관 레지스트리 연구
장윤경,송태진,김용재,허지회,이경열,김영은,장민욱,조수진,강석윤 이화여자대학교 의과학연구소 2017 EMJ (Ewha medical journal) Vol.40 No.3
Objectives: Although there have been several reports that described characteristics for young age stroke, information regarding very young age (18–30 years old) has been limited. We aimed to analyze demographic factors, stroke subtype, and 3-month outcome in acute ischemic stroke patient who have relatively very young age in multicenter stroke registry. Methods: We evaluated all 122 (7.1%) consecutive acute ischemic stroke (within 7 days after symptom onset) patients aged 18 to 30 from 17,144 patients who registered in multicenter prospective stroke registry, 1997 to 2012. Etiology was classified by Trial of Org 10172 in Acute Stroke Treatment criteria. Stroke severity was defined as National Institutes of Health Stroke Scale (NIHSS) and stroke outcome was defined by modified Rankin scale (mRS) at 3 months after index stroke. Results: The mean age of all included patients was 25.1±3.7 years and 76 patients (62.2%) were male. The median NIHSS at admission was 4. Considering stroke subtype, 37 patients (30.3%) had stroke of other determined etiology (SOD), 37 (30.3%) had undetermined negative evaluation (UN) and 31 (25.4%) had cardioembolism (CE) were frequently noted. After adjusting age, sex and variables which had P<0.1 in univariable analysis (NIHSS and stroke subtype), CE stroke subtype (odds ratio, 4.68; 95% confidence interval, 1.42–15.48; P=0.011) were significantly associated with poor functional outcome (mRS≥3). Conclusion: In very young age ischemic stroke patients, SOD and UN stroke subtype were most common and CE stroke subtype was independently associated with poor discharge outcome.
Ethylenediaminetetraacetic acid(EDTA)항응고제에 의한 Mean Corpuscular Volume(MCV)변화
홍승민,박영진,최하영,임진,정옥연,이호준,이호영,장숙진,문대수 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.2
It is essential that we put the anticoagulant into the blood specimen of the CBC test. However, the value of some parameters in the CBC test can be changed whenever using some anticoagulants. EDTA anticoagulant is mostly used these days. There are 3 kinds of EDTA, that is K_(2-), K_(3-), and Na_(2-) EDTA. The author studies how many effects each the EDTA gets into the true value of blood specimen for MCV of RBCs. Especially we compared the MCV effect of different concentrations of 3 EDTA anticoagulants on the bias with time and instrument. Some results are gotten. In our results, K_(3-)EDTA anticoagulant shows more satisfactory MCV value than K_(2) or Na_(2-)EDTA. On using concentration of EDTA, 1.5㎎ EDTA/㎖ of blood show more satisfactory MCV value than 7.5㎎ EDTA/㎖ of blood. However, the choice of anticoagulant may be dependant on the different instruments.
Ko, Il Gyu,Jeong, Jin Woo,Kim, Young Hoon,Jee, Yong Seok,Kim, Sung Eun,Kim, Sang Hoon,Jin, Jun Jang,Kim, Chang Ju,Chung, Kyung Jin Korean Continence Society 2014 International Neurourology Journal Vol.18 No.2
<P><B>Purpose</B></P><P>Aging-induced loss of muscle mass and subsequent reduction of strength is a fundamental cause of frailty, functional decline, and disability. And this may lead to muscular dysfunction, voiding dysfunction, or urinary incontinence due to pelvic muscle weakness induced by aging. Physical exercise has been recommended for the prevention and the treatment of these age-related frail states. We investigated the effects of treadmill exercise on muscle strength, myostatin mRNA and protein expression, and gastrocnemius myocytes proliferation in aged rats to investigate the possible antiaging effects of aerobic exercise on skeletal muscles such as pelvic floor muscles and urethral rhabdosphincter muscle.</P><P><B>Methods</B></P><P>In this study, 5-month-old male Sprague-Dawley rats were used as the young-age group (n=20) and 24-month-old rats were used as the old-age group (n=20). Each group was randomly divided into two groups (n=10 in each group): the sedentary and the treadmill exercise group. The rats in the exercise groups were forced to run on a motorized treadmill for 30 minutes, once a day, for 6 weeks. For this study, a weight load test, hematoxylin and eosin staining, real-time and reverse transcription polymerase chain reaction for myostatin mRNA, myostatin western blot, and 5-bromo-2'-deoxyuridine immunohistochemistry were performed in the gastrocnemius muscle.</P><P><B>Results</B></P><P>The age-induced reduction of muscle mass and strength was associated with a decrease in myocyte proliferation and an increase in myostatin mRNA and protein expression in the gastrocnemius. However, treadmill exercise improved muscle mass and strength through suppression of myostatin mRNA and protein expression, and myocyte proliferation increase in the gastrocnemius against the aging process.</P><P><B>Conclusions</B></P><P>Aerobic exercise is a useful strategy for enhancing muscle function against aging-induced loss of skeletal muscle mass and functions.</P>
[논문]보양조건 및 타설주기를 고려한 매스 콘크리트 구조물의 수화열 해석
이영호,서기영,최덕락,엄장섭,진치섭* 釜山大學校生産技術硏究所 2004 生産技術硏究所論文集 Vol.63 No.-
콘크리트 구조물의 공용수명은 콘크리트 재료의 초기에 발생하는 수화열에 의해 아주 큰 영향을 받는다. 수화열은 콘크리트의 열전달 및 열응력 특성으로 결정되어지는 온도균열지수를 통해 분석되고 있다. 본 연구에서는 이러한 온도균열 지수의 분석을 통해 매스 콘크리트 구조물의 시공시 적절한 시벤트 종류, 보양방법,타설주기 및 타설높이 둥 최적의 시공방안 구하는데 도움을 주어 향후 시공 예정인 매스 콘크리트 구조물에 발생 가능한 온도균열을 미리 예측하여 이를 방지하기 위한 시공 방안을 제안하는데 그 목적을 두고 있다.
무인감시시스템 구현을 위한 이동체 인식 알고리즘에 관한 연구
장국렬,방만원,박진홍,박순영 木浦大學校 情報産業硏究所 1996 情報産業硏究誌 Vol.4 No.-
In this paper, an effective algorithm which can detect moving objects from the image sequences and classify an intruder from other moving objects is presented for an implementation of unmanned surveillance system. The proposed algorithm uses a stick figure model for features of the moving object since the stick figure model can be represent the characteristics of the moving objects. The stick figure model is extracted by applying the thining algorithm to the binary difference image between the reference and the image of a moving object. The computer simulation is carried out to analyze the performance of the proposed algorithm. The results show that the algorithm can discriminate a moving person and a moving animal with high degree of reliability.
천연가스 사용 난방 및 산업보일러의 NOx와 CO 배출계수 산정 연구
장영기,최상진,김관,송기봉,김호정,정봉진 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.5
This study was conducted for developing the emission factors of nitrogen oxide(NOx) and carbon monoxide (CO) from the combustion boilers burning liquefied natural gas (LNG). These emission factors were compared with those of U.S. EPA and European Environment Agency (EEA). NOx and CO concentration in the flow gas were measured using Kane-May, KM9106 and Thermo Environmental Instruments Inc., 42C-HL. Measurement were conducted at thirty industrial and commercial LNG boilers. Emission factors were calculated on the basis of fuel consumption (kg-pollutant/㎥-fuel burned). NOx concentration at industrial boiler was 14~125 ppm and it was measured as 35~125 ppm at commercial boiler. NOx emission factors of industrial boiler and commercial boiler were 1.84kg/㎥ and 2.09kg/㎥, respectively. NOx emission factor of commercial boiler was higher than that of industrial boiler. The NOx emission factors estimated in this study were lower than those of U.S. EPA and higher than those of EEA. Average CO emission factor of industrial boiler was 0.65 kg/㎥ and at commercial boiler it was 0.70kg/㎥, CO emission factor at industrial boiler was lower than that at commercial boiler.
공분산구조분석법을 활용한 통행수단, 활동 및 통행행태에 대한 인과성 평가
장태연,김대영,김정호,권진영 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-
Activities done by individual are usually classified into obligatory and discretionary ones. Simple or complex trip pattern is performed as these activities are linked and various travel modes are used. Individuals try to link several trips as a type of chain to save transportation resources such as travel distance or time, which consequently produces complex trip pattern. These changes in urban transportation environment and less studies on activity-based characteristics make difficult to forecast trips resulting from trip linkage behavior. The purpose of study is to analyze possible causal relationships among activities, travel mode choices and travel patterns, assuming that they are directly influenced by individual or household attributes. Two kinds of models are established to achieve this purpose. One is the allocation model for mode choice for activities by three stage least square estimation method under the restricted conditions. The other is covariance structure model(LISREL) to analyze direct and indirect effect among attributes. As a result, the allocation of travel modes is mainly influenced by variables such as gender, education level, marriage, and children under 13 years old. In LISREL, it is shown that those variables well explain an exogenous personal attributes and only family income do an exogenous household attributes. While trip pattern attributes is well reflected by travel mode attributes, it is less reflected by activity attributes.