Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

Mongolian Gerbil과 CJU/A Mouse의 와우에서 βNADPH Diaphorase의 발현 양상

추무진,김진섭,송창근,신시옥,진홍률 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.11

Effect of Fixation Time and Freeze-thaw Cycles on the Molecular Analysis of Viral DNA

Ok-jin Kim 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

of Fixation Time and Freeze-thaw Cycles on the Molecular Analysis of Viral DNAOk-jin Kim*United States Department of Agriculture-ARS, Animal Disease Research UnitReceived May 20, 2003 / Accepted July 13, 2003J. Vet. Sci. (2003), 4(2), 203-204*Corresponding author: Ok-jin Kim USDA-ARS, ADRU, 319 Bustad, WSU, Pullman, WA 99164, USA Tel: 1-509-335-6046, E-mail: kimoj@netian.com

고대의 동이인식

송옥진 ( Ok Jin Son ) 국제뇌교육종합대학원 국학연구원 2013 선도문화 Vol.14 No.-

많은 학자들은 만주 요동지역이 고조선시대 강역이었다고 말한다. 또한 그 지역에 존재하던 민족구성을 동이족으로 파악하여 우리 선조의 토대로 이해하고 있다. 따라서 그간 국내 학자들에 의해 연구된 ‘동이’의 의미를 확인하고 중국측 기록에서 인식된 ‘동이’와 그들의 사서를 인용하는 우리의 동이인식은 어떤지를 살펴보고자 한다. 중국의 관찬사서인『한서』에는 “東夷天性柔順”이라는 구절이 있어 우리민족은 그 천성이 온순하고 좋다는 인식이 확산되었다. 또한 『삼국지』「오환선비동이전」 에는 부여, 고구려 등 고조선 이후 우리 민족 명칭이 나와 있어 이후 우리 역사가 동이전에 편입되는 시초가 되었다. 『후한서』 에는 “동방이 곧 夷이고 夷는 곧 뿌리다” 라는 구절로써 ‘우리 민족은 근원이다’라는 해석을 하게 한다. 그러나 이러한 각 구절만으로 우리 민족성향과 역사를 추론한다는 것은 매우 위험한 발상이 아닐 수 없다. 따라서 본 글에서는 각 구절을 확인하는 한편 고조선으로 통칭되는 우리민족의 설정을 중국측에서는 어떻게 했는지 확인해보고자 한다. 또한 중국 최대의 성인인 공자의 동이인식과 만주지역을 기반으로 한 고조선지역을 통칭하는 ‘맥’에 대해 공자는 어떻게 인식하였는지 확인해보도록 한다. We have called us not ``Hanminjoek``, but ``Dongyijoek`` in these days. It begins with argument that ``Dongyijoek`` had influenced on Chinese or ``Whahajoek``. Especially, this arguments almost emphasize superiority of our nation (Dongyi) with anecdote that The Master ``confucius`` admired ``Dongyi``. So, We have replace meaning of ``Dongyi`` by something to mean our nation in a dictionary. But ``Dongyi`` just means ``Eastern barbarian``, surrounded enemy from China. We recognized ``Dongyi`` as our nation after middle of Choson era. There are some mention in a old bood the latter part of Choson era. In a Chinese record, at first, ``Dongyi`` menas many nations to live in Sandong peninsula and Huai River. And it means all nations to live in eastern ``Liaoning Sheng``. In ``before Jin’, ``Maek`` is word that means north eastern China area, but it is intentionally changed and combined. In Chinese record a first opinion to ``yi`` is just far away area by Sima-Qian`s old history book. It was changed a humble name to near surrounded force at the Age of Chinese Warring States. And then some force was powerful, so the included ``Manju`` and ``Hanbando`` among ``Dongyi``. Now China will assimilate ``Dongyi`` there history. But ``Dongyi`` occurred frequently just at Choson era. We have to record the history with independance history mind froe one word ``Dongyi``. We don`t insist on our opinion that our history is right. But more important thing is that we never allow another opinion to history intactly. For that we need to observe and express our history on our point of view not Sinocentrism.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

영어 환유의 개념구조연구

이진옥 대한언어학회 2000 언어학 Vol.8 No.1

Lee, Jin-ok. 2000. A Study on the Conceptual Structure of Metonymy in English. Linguistics 8-1, 153-169. This paper is to deal with metonymy in framework of Conceptual Graph Theory. Conventionalized metonymy is stored in the metonymical schemata. They include container for its contents, cause for the effect, producer for its products, instrument for its user, part for the whole, artist for his work, controller for the controlled, institution for people responsible, place for the institution, place for the event. By using the various metonymical relation, the expressions are represented properly and explicitly. To formalize figures, especially metonymy, with conceptual graph helps to process the natural language. (Chungnam National University)

참 빛으로 함께 걸어가는 길: 지학순 주교의 가르침 안에서 나타난 현대 청소년 사목 방향에 관한 연구

이진옥(Lee, Jin Ok) 광주가톨릭대학교 신학연구소 2021 神學展望 Vol.- No.213

제2차 바티칸 공의회를 중심으로 보편 교회는 청소년에 대한 인식의 변화를 보인다. 단순히 신앙 교육의 대상이었던 청소년의 주체성(Subjectivity)을 강조하면서 청소년이 능동적으로 교회 선교 사명에 참여하며, 자기 삶 안에서 하느님 사랑과 이웃 사랑을 구체적으로 실천하며 살아가길 요청한다. 이러한 보편 교회의 요청은 지학순 주교의 행적과 가르침 안에서도 나타난다. 지학순 주교는 진광학원 설립을 통해 청소년의 지식적인 성장뿐만 아니라 전인적인 성장을 지향하며 사회 정의를 실현하고 공동선에 이바지할 수 있도록 인도했다. 또 지학순 주교는 청소년이 인류와 사회의 미래일 뿐만 아니라 교회와 사회를 더욱 젊게 해주는 데 중요한 역할을 한다고 확신했다. 그래서 1973년 사목 지침 ‘생활 속에서 그리스도를 찾자’에서 지학순 주교는 청년을 모든 활동의 중심에 두었다. 청년회가 중심이 되어 지금까지의 형식적인 신앙 활동에서 벗어나 교회 선교 사명에 능동적으로 참여하기를 바랐다. 이를 통해 그 당시 교회가 영성 생활과 사회 행동에 있어 잃어버린 교회의 청춘을 회복하고, 청년은 교회를 통해 신앙의 눈으로 세상을 바라보며 사회 정의가 이 사회에 실현되길 바랐다. 지학순 주교는 제2차 바티칸 공의회가 바라는 청소년의 능동적인 참여에서 한발 더 나아가 제15차 세계주교대의원회의에서 주장한 대로 청소년은, 교회와 함께 걸으며 사회 정의를 실현하고 공동선에 이바지하며 세상 안에서 하느님 사랑과 이웃 사랑을 구체적으로 실현하며 살아가길 바랐다. 그리고 이것은 오늘날 보편 교회가 강조하는 공동합의적 교회의 모습이기도 하다. 이처럼 지학순 주교의 청소년에 대한 관심은 현대 청소년 사목 방향을 찾는 데 큰 도움이 될 것이다. This study tried to find the direction of modern Youth Ministry base on the teaching of Bishop Tji Hak Soun. The Second Vatican Council was convinced that the youth can help the Church keep herself young. Consequently the subjectivity of young people to evangelizing the world was emphasized. Especially, the Church clearly organized the role of young people to realize the issue of social justice and to aspire for the common good in their daily life. For this, the Council asked young people look upon the Church’s youthful energy. Pope Francis recommended an importance of the positive role of young people for renewal in the Church and society in the Post-Synodal Exhortation 『Cristus Vivit』. In this document, he clearly appeals to the relationship between the Church and youth. The Church needs young people to keep her young and can prevent her from becoming corrupt. In addition, young people can discern their life through the vision of faith. Like this idea of the universal Church can be discovered in the teaching of Bishop Tji Hak Soun. He looked to young people with confidence and with love. He believed that young people are the hope of the Church and society for its renewal. Therefore he stressed their positive participation in the mission of the Church and what the universal Church expected to young people. This idea can be found in the establishment of the Jin-Kang Institute and in his pastoral letter of “Find Christ in our daily life” (1973). Bishop Tji, aimed to develop not only their intellectual growth but also their moral and spiritual growth. Moreover, when he tried to implement his pastoral letter, 1973, he put young people at the core of it. He hoped young people would evolve from a formal faith life and find their identity as a good Christian and thereby finally, be involved in the evangelization of the world. Moreover, they can help the Church keep her young people and vitalize their enthusiasm to build of Kingdom of God into the world. Beside, young people can decide their life towards God through their vision of faith as emphasized from the universal Church and thus realize the understanding of Synodality. From here, we can find the direction of modern Youth Ministry. Obviously, Youth ministry and young people should seek the path of Synodality. Young people is not any more the objective of faith education or formation, but they are the protagonists who have a great responsibility to participate in the mission of the Church for evangelization.

Ethylenediaminetetraacetic acid(EDTA)항응고제에 의한 Mean Corpuscular Volume(MCV)변화

홍승민,박영진,최하영,임진,정옥연,이호준,이호영,장숙진,문대수 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.2

It is essential that we put the anticoagulant into the blood specimen of the CBC test. However, the value of some parameters in the CBC test can be changed whenever using some anticoagulants. EDTA anticoagulant is mostly used these days. There are 3 kinds of EDTA, that is K_(2-), K_(3-), and Na_(2-) EDTA. The author studies how many effects each the EDTA gets into the true value of blood specimen for MCV of RBCs. Especially we compared the MCV effect of different concentrations of 3 EDTA anticoagulants on the bias with time and instrument. Some results are gotten. In our results, K_(3-)EDTA anticoagulant shows more satisfactory MCV value than K_(2) or Na_(2-)EDTA. On using concentration of EDTA, 1.5㎎ EDTA/㎖ of blood show more satisfactory MCV value than 7.5㎎ EDTA/㎖ of blood. However, the choice of anticoagulant may be dependant on the different instruments.

패류중 중금속함량에 관한 연구

신현수,허옥순,이진하,김세은,주인선,신동우,강석종,박만종,김지연,김근희,강숙경,정래석,허숙진,소유섭,최장덕,문병우,김진수 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

본 연구는 패류중 중금속함량 측정을 위한 분석효율이 높고 간편한 분해법을 찾아내어 그 방법에 의끓 유종중인 패류중 중금속함량을 파악하고자 수행하였다. 시료를 분해시키는 Microwave와 습식, 건식회법을 비교한 결과 변형습식회화르가 가장 적합하였다. 변형습식회차딘는 려린0,3+C104+H2SOf의 혼찰산을 쪼 · j 1 (v/v)의 비율로 혼합하여 사용하였 을 때 회수을 Pb린틴. Cd 97.8, Cu 94.2, Zn 92.8%를 나타내었근 분해시간은 2~2.5시간 소요되었다. 유통중인 패류중 중금속함량 」최소~최대(평균), mgAgl 은 Pb 0.028~o.528(0.153), Cd 0.OO7~1,832(0.587), Cu 0.360~37.375(4.6691, Zn 6.317~233.2iO(38.881), Hg 0.001 ~O.151(0.012)mg/ltg으로 나타났다. 또한 유통중인 5종의 패류중 중금속평균항량이 생산지 하재지역에서 구입한 패류에 비해 모든 중금속언써 약간 높은 함량을 보였으나 오염된 수준이 아닌 자연함유량수준이었다. This study was conducted to improve the digestion method for the determination of heavy metals in shellfishes and to estimate the contents of heavy metal in commercial shellfishes by their digestion method. This digestion method was compared microwave with wet and dry ash digestion for shellfish samples, obtained results showed that the modified wet ash Ⅱ digestion was convenient and easy to use. For the modified wet ash Ⅱ digestion, The mixed acid of HNO₃+HClO₄+H₂SO₄(25:5:1, v/v) was used. Under this condition, Recoveries were Pb 94.3, Cd 97.8, Cu 94.2 and Zn 92.8% and digestion time was ∼2.5 hours. The contents of heavy metal [minimum∼maximum (mean), mg/kg in commercial shellfishes were as follows ; Pb:0.028∼0.528(0.153), Cd:0.007∼1.832(0.587), Cu:0.360∼37.375(4.669), Zn:6.317∼233.250(38.881), Hg:0.001∼0.151(0.013). The contents of heavy metal in commercial shellfishes of five species were slightly greater than those of shellfishes purchased at Hajae. There was no great difference between the contents of heavy metal of Hajae and those of shellfishes purchased at Whole market.

Ethylenediaminetetraacetic acid (EDTA)항응고제에 의한 Mean Corpusculaar Volume(MCV)변화

홍승민,박영진,최하여,임진,정옥연,이호준,이호영,장숙진,문대수 조선의대 1996 The Medical Journal of Chosun University Vol.21 No.2