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Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향
장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-
The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....
Kim, Soo-Jin,Rim, Kyung-Taek,Kim, Jong-Kyu,Kim, Hyeon-Yeong,Yang, Jeong-Sun Occupational Safety and Health Research Institute 2011 Safety and health at work Vol.2 No.1
Objectives: In this study, the in vitro mammalian chromosomal aberration (CA) assay was conducted to gain additional information concerning the hazards associated with the use of cyclopentane and ammonium nitrate. While these two chemicals had already been tested by many methods, they had not been studied in the CA test. Methods: The assay was performed using the ovarian infantile cell (CHO-K1 cell), by the direct method (-S9) and by the metabolic activated method (+S9 mix). Results: Using the direct method, the 7 dosages in a 48 hour treatment group did not show that the frequency of CA is proportion to the dosage addition. The frequency of CA is not proportion to the dosage addition for a 6 hour treatment using the metabolic activated method. Conclusion: From these findings, it was decided that the 2 chemicals do not induce chromosomal aberrations under the tested conditions.
Kim, Jong-Kyu,Kim, Soo-Jin,Rim, Kyung-Taek,Cho, Hae-Won,Kim, Hyeon-Yeong,Yang, Jeong-Sun The Korean Society of Toxicogenomics and Toxicopro 2009 Molecular & cellular toxicology Vol.5 No.2
The usage and types of chemicals are advancing, specializing, large-scaled increasing, and new chemical exposed workers are concerning to occupational disease. The generation of reactive oxygen in the body from carcinogen, mutation and DNA damage in cancer is protected by natural antioxidants (phytochemicals) with antimutagenic effect. There were many reports of ginsenoside Rb$_1$, Rg$_1$ grievances of the genetic mutation to suppress the effect confirm the genetic toxicity test with chromosomal aberration test and the Comet (SCGE) assay confirmed the suppression effect occurring chromosomal DNA damage. We had wanted to evaluate the compatibility and sensitivity between the chromosomal aberration (CA) test and the Comet assay. We used the CA test and Comet assay to evaluate the anti-genotoxicity of ginsenoside Rb$_1$ and Rg$_1$, in CHO-K1 (Chinese hamster ovary fibroblast) cell in vitro, composed negative control (solvent), positive control (benzo[a]pyrene), test group (carcinogen+variety concentration of ginsenoside) group. The positive control was benzo[a]pyrene (50 $\mu$M), well-known carcinogen, and the negative control was the 1 % DMSO solvent. The test group was a variety concentration of ginsenoside Rb$_1$, Rg$_1$ with 10$^{-8}$%, 10$^{-6}$%, 10$^{-4}$%, 10$^{-2}$%, 1%, 10%. In chromo-somal aberration test, we measured the number of cells with abnormally structured chromosome. In Comet assay, the Olive tail moment (OTM) and Tail length (TL) values were measured. The ratio of cell proliferation was increased 8.3% in 10$^{-8}$%, 10$^{-6}$%, 10$^{-4}$%, 10$^{-2}$%, 1%, 10% Rb$_1$ treated groups, and increased 10.4% in 10$^{-10}$%, 10$^{-8}$%, 10$^{-6}$%, 10$^{-4}$%, 10$^{-2}$%, 1% Rg$_1$ treated groups. In the CA test, the number of chromosomal aberration was decreased all the Rb$_1$ and Rg$_1$ treated groups. In the Comet assay, the OTM values were decreased in all the Rb$_1$ and Rg$_1$ treated groups. To evaluate the compatibility between CA and Comet assay, we compared the reducing ratio of chromosomal abnormalities with its OTM values, it was identified the antimutagenicity of ginsenoside, but it was more sensitive the CA test than the Comet assay. Ginsenoside Rb$_1$ and Rg$_1$ significantly decrease the number of cells with chromosomal aberration, and decrease the extent of DNA migration. Therefore, ginsenoside Rb$_1$, Rg$_1$ are thought as an antioxidant phytochemicals to protect mutagenicity. The in vitro Comet assay seems to be less sensitive than the in vitro chromosomal aberration test.
Kim, Ho-Rim,Yu, Soonyoung,Oh, Junseop,Kim, Kyoung-Ho,Oh, Yun-Yeong,Kim, Hyun Koo,Park, Sunhwa,Yun, Seong-Taek Elsevier 2019 Agriculture, ecosystems & environment Vol.286 No.-
<P><B>Abstract</B></P> <P>The excessive application of nitrogen in agro-livestock farming areas has led to serious groundwater contamination around the world; thus, the efficient control of N loads is crucial to manage nitrate contamination of groundwater. In this study, to suggest an optimal N application limit as a key guideline of N management, we examine the impact of anthropogenic N loading on nitrate levels of shallow groundwater, using a large dataset (<I>n =</I> 4,000) collected in 2012–2014 from 100 agro-livestock farming districts in South Korea. Not considering the time lag and legacy problem, quantile regression is performed to overall assess the relationship between nitrate contamination and anthropogenic N input across the full range of conditional distribution of groundwater nitrate concentrations because of heteroscedasticity. As a result, positive gradients (<I>β<SUB>τ</SUB> </I>) meaning the rates of changes are found between groundwater nitrate concentrations and land-derived N loads at all quantiles; <I>β<SUB>τ</SUB> </I> increases as the quantile is higher and is as large as 36.48 ± 10.73 mg NO<SUB>3</SUB> <SUP>−</SUP>/L per land-derived N input (on a log scale) at the 90% quantile. The quantile map indicates that the high gradient (i.e., the large sensitivity to N loading) is related to agricultural land use, low elevation, and low topographic slopes. In fact, groundwater nitrate concentrations increase as the percentage of agricultural land increases but the percentage of forest, elevation and slope angle decreases, which suggests that land use, elevation, and slope should be considered when attempting to evaluate N application limits. This study suggests the N limits below 170 kg ha<SUP>-1</SUP> year<SUP>-1</SUP> based on the drinking water standard (44.3 mg/L as NO<SUB>3</SUB> <SUP>−</SUP>) at the quantiles higher than 70% which mostly occur in flat agricultural lowland areas. Our method used in this study can be applied elsewhere to establish efficient management practices for groundwater nitrate contamination, considering local environmental factors.</P> <P><B>Highlights</B></P> <P> <UL> <LI> An empirical relationship between N inputs and groundwater nitrate levels over S. Korea. </LI> <LI> Results of quantile regression is useful to suggest optimal N application limits. </LI> <LI> Nitrate contamination is more sensitive at higher quantiles toward low-lying lands. </LI> <LI> N application limit below 170 ha<SUP>−1</SUP> year<SUP>-1</SUP> is suggested for typical agricultural areas. </LI> </UL> </P>
김영서 ( Yeong-seo Kim ),김규현 ( Gyu-hyun Kim ),정예림 ( Ye-rim Cheong ),고나영 ( Na-yeong Go ),이경용 ( Kyung-yong Lee ) 한국정보처리학회 2020 한국정보처리학회 학술대회논문집 Vol.27 No.2
코로나 19사태로 인한 ‘사회적 거리두기’ 운동이 지속되면서 사람들의 생활 형태가 변화된 양상을 띈다. 특히 모임 활동 및 단체 활동의 제한으로 개인 시간이 이전에 비해 증대되었다. 홀로 자택에 머무르는 시간의 증가로 인해 사회적 단절감과 고립감이 심화되며 “코로나 블루”로 일컫어지는 신종 정신질환이 많은 사람들에게 생겨나 사회적 문제로 이슈화 되고 있다. 본 논문에서는 이러한 사회적 문제를 완화시키기 위해 고안된 새로운 디퓨저 개발과정 및 기존 디퓨저에서 볼 수 없었던 IoT기술과 조향기술과의 접목을 통한 차별성에 대해 서술하였다.