Inoue Balloon을 이용한 PMV의 장·단기 결과 분석

진은선,이연아,전숙,김현숙,정승묵,박상선,최락경,임달수,홍석근,황흥곤 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

구강점막 부착용 케토프로펜 고분자 필름의 제조 및 평가

박진석,이상은,강봉석,이경록,이은주,박정숙 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

Abstract – The objective of this study was to prepare ketoprofen-loaded buccal adhesive patch. The adhesive patch was formulated by casting method using aqueous soluble polymer povidone K17 (PVP 17PF) as film-forming agent and hydroxypropylmethylcellulose (HPMC) as adhesive agent. To compare the effect of HPMC type, different molecular weight of K4M and K15M HPMC was used. The physicochemical properties of patches such as appearance, thickness, in vitro release, and adhesiveness were investigated. The concentration of ketoprofen was determined spectrophotometrically at a wavelength of 233 nm. The appearance of prepared patches was semi-transparent, light-yellow or almost colorless, and odorless. Thickness of each patches (n=6) was 0.895 ± 0.033 mm for K4M patch and 0.727 ± 0.036 mm for K15M patch. In vitro release test, both K4M and K15M patches showed over 20% release within 30 min. At 120 min, K4M and K15M patches demonstrated 95% and 67.5% release of ketoprofen, respectively, and up to 240 min, both patches released drug completely. Maximum adhesive force of K4M and K15M patches was 6.571 ± 2.703 gf and 2.735 ± 1.151 gf, respectively. Moreover, it took 28.29 ± 0.38 sec and 28.30 ± 0.34 sec for K4M and K15M patch to peel off them after adhesion, showing no significant difference. In conclusion, thickness, in vitro release, and maximum adhesive force could be modulated by alteration of polymer types.

Goldman's Algorithm을 이용한 비외상성 흉통 환자의 분석

조석진,유진현,김찬웅,어은경,정구영 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Back ground : It is important to evaluate the patient presenting with non-traumatic chest pain in emergency department, and it is also difficult to classify appropriately. The purpose of this study is to predict probability of acute myocardial infarction(AMI) and assess the group for low probability of AMI that is target for observation-unit of chest pain in emergency department. Methods : A prospective, clinical study was performed from March 1998 to August 1998 at the department of emergency medicine, Ewha Womans University Mokdong hospital. We classified high-probability group and low-probability group of AMI according to Goldman's algorithm and then compared with the final diagnosis. Results : The study included 218 patients. 84 patients(39%) was the high-probability group and 134 patients(61%) was the low-probability group of AMI. As compared with final diagnosis, AMI was 47 patients(56%) among the high-probability group and 1 patient(0.7%) among the low-probability group. We observed sensitivity of 98%, specificity of 78% in predicting AMI. Conclusion : The classification according to Goldman's algorithm may be useful predictor of AMI and improve triage for emergency department patients with chest pain. It is also helpful for management of observation-unit of chest pain in emergency department.

정신보건법의 주요 쟁점 조항에 대한 선진국과의 사례 비교

홍진표,황순찬,박수빈,서동우,정은기,김진학,박종익,안주연,김수정,장홍석 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.2

Objectives The Mental Health Act is an initiative aimed at changing and shaping mental health services and protecting human rights of persons with mental disorders. Since the Mental Health Act was legislated in 1995, four amendments have been made according to the issues that arose from public concerns. However, there are still many debates about the human rights protection of the mentally iII. This study aimed to provide information regarding major aspects of the Mental Health Act by comparing them among several developed countries. Methods Current Mental Health Acts of the state of Michigan in the United States, Scotland in England, the state of Victoria in Australia, and Japan were reviewed. Issues regarding the Korean Mental Health Act were collected from seminar materials, news media contents, and mental health professionals Results The definition of subjects in Korean Mental Health Act was more inclusive than other countries and was derived from a medical classification of mental illness. Family members or guardians were granted important responsibilities for deciding the involuntary admission of mentally ill patients in Korea and Japan. In Western countries, Mental Health Review Tribunals or courts have the primary responsibility for important decisions about mentally ill patients. The regulation of immediate dis- charge after request by voluntarily admitted patients was not enacted in all countries except Korea. The mandatory procedure for involuntary admission in Western countries includes an individual case review with personal interview by a Mental Health Review Tribunal or court. Conclusion The Korean Mental Health Act appears to meet the basic standards of Guidelines from international organizations. Our traditional culture and inherent health systems seem to influence the legal regulation of mental health service and might be related to the problems of human rights protection of mentally ill patients in Korea.

충남대학교병원 마취발전의 경향에 관한 분석 : 1967년부터 - 1996년까지 from 1967 to 1996

최세진,김상수,정규돈,윤석화,신용섭,손수창,이원형,김혜자,이정은 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

To evaluate the specificity and historical trends of the anesthesia in Chungnam National University Hospital, anesthetic experiences of 83,572 in total performed at Chungnam National University Hospital from January 1967 to December 1996 were analyzed statistically and clinically according to age, sex, surgical department, physical status, elective and emergency surgery, premedicants, IV anesthetics, anesthetic methods, inhalational anesthetics, muscle relaxants. The results were as follows : 1. The number of cases has been steadily increased year by year. 2. The ratio of male to female was 52.8% : 47.2%. 3. According to the age, There were 44,905 cases (54%) in the group of 13-45 years. 4. According to the ASA classification of physical status, most of the cases were belonged to the class 1 & 2 (72.5%). 5. The ratio of elective to emergency was 79.4% to 20.6%. 6. Recently, glycopyrrolate has been used increasingly. 7. Thiopental sodium has been mainly used for intravenous induction agent. 8. General anesthesia has been used mainly. 9. Enflurane is the most common inhalational anesthetic agent. but Isoflurane has been used increasingly. 10. Most of muscle relaxants are Pancuronium & Vecuronium(84.5%).

음양곽과 함초의 간독성에 대한 연관성

하배진,남천석,박은경,강금석 신라대학교 자연과학연구소 2006 自然科學論文集 Vol.15 No.-

In the present study the hepatoprotective and antioxidative effects of Epimedium koreanum (EK) and Salicornia herbacea (SH) were investigated against carbon tetrachloride (CCl_(4))-induced liver damage in rats. EK and SH (100 mg/kg) were administered into rats intraperitoneally (i.p) for 2 weeks. After CCl_(4) a dose of 3.3ml/kg was administered to induce hepatotoxicity. This antioxidative effects of EK and SH on CCl_(4) -treated rats were measured through the activity of Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) in serum and Superoxide dismutase (SOD), Catalase (CAT) in liver tissue. EK or SH-administered and CCl_(4) -treated (ECT or SCT) groups showed inhibitory effects in AST and ALT activities compared to CCl_(4) -treated control (CTC) group. SOD and CAT in ECT and SCT groups were increased compared to those of CTC group.

스트레스 측정도구의 표준화 방안

장세진,차봉석,박종구,이은경 연세대학교 원주의과대학 1994 원주의대논문집 Vol.7 No.1

수직적 안모유형에 따른 치료 후 교합평면 안정성에 관한 연구

박정은,차경석,이진우,정동화 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.5

본 연구는 수직적 안모유형에 따른 치료 후 교합평면 변화양상을 조사하여 향후 적절한 치료계획과 기전의 설정에 도움이 되고자 시행하였다. 골격성 1급 부정교합으로 진단되어 비발치로 치료받은 성인 60명(남자 28명, 여자 32명)을 대상으로 하였으며, Ricketts법의 facial axis, facial depth, mandibular plane angle, lower face height, mandibular arc의 5개 항목을 이용하여 한국 성인의 정상교합자 통계치의 기준에 따라 short face type (1군), average face type (2군), long face type (3군)으로 분류하였다. 각 군의 치료 전, 치료 종료, 종료 후 1년의 측모두부 방사선사진 계측치를 비교 분석하였다. 1군은 치료 종료 시와 비교하여 유지기간에 일반적 교합평면각, 기능적 교합평면각, L6/L1, MP-L6 항목이 유의하게 감소하였고 (p<0.01) L1-FOP 항목은 유의하게 증가하였다(p<0.001). 2군은 유지기간에 유의한 변화를 보이지 않았으며 3군은 유지기간에 기능적 교합평면각이 유의하게 증가하였다(p<0.05). 기능적 교합평면각의 치료 후 변화량은 각 군 간에 유의한 차이를 보였으며 특히, 1군과 3군 간에 매우 큰 유의성을 보였다. 따라서 치아의 압하, 정출 및 치료 후 전치부 피개 등에 있어 유지기간 중 교합평면각 변화의 고려가 필요하다고 생각된다. Objective: The purpose of this study was to find changes in the occlusal plane related to different vertical facial patterns and suggest treatment goals and conduct possible treatment mechanisms. Methods: 60 adult patients (28 males, 32 females) who had been diagnosed as Class I skeletal malocclusion and treated without extraction were selected. Patients were divided into three groups; short face type (group 1), average face type (group 2) and long face type (group 3), using the data on normal occlusion of Korean adults. Results: The results were achieved by analyzing cephalometric tracings of each group at pre-treatment, end-treatment and post-treatment (about 1 year recall check). The inclination of the occlusion plane tends to gradually increase as the face becomes longer. In group 1, COP-X, FOP-X, L6/L1, MP-L6 were significantly decreased, and L1-FOP was significantly increased during the retention period (T3-T2). Group 2 showed no significant change. In group 3, FOP-X was significantly increased during the retention period (T3-T2). During the retention period, FOP-X showed significant change among each group, especially between group 1 and group 3. Conclusion: These results suggest that changes of occlusal plane inclination according to facial vertical pattern need to be considered during the retention period for intrusion, extrusion, and incisor overbite.

한국 초기 근대 무용 연구 : 조택원, 최승희의 작품을 중심으로

박연진,김효순,정은주,문희숙 경희대학교 체육과학연구소 2000 體育學論文集 Vol.28 No.-

Many changing mankind's thought and recognition have affected our history, it is same that dance has become a new concept-dance art under the concept that experiment of a new formality and change are creation. Dancer's feeling is exposed through dance is a phenomenon of carrier which independently embodies self. Dance is a harmony between time and space and a harmony made by rhythmic movement and dance composition. Dance is an art expressing feeling and some situations intentionally dr not by moving its body. The way of communication has been changed since the introduction of the New Dance. In traditional dance, there was no sharply defined boundary to divide spectators and performers, that is, the object and the subject of communication. With the New Dance, there established modern theatres, which separated performers from spectators. With the New Dance, the dance itself became interpretive activity. The New Dance remodelled the traditional dance and introduced some element of ethnic dance from other countries. For example, the costume became so diversified in the New Dance that the range of expression also became expanded greatly.

가토 두정골 절단시 회전기구의 회전속도와 생리 식염수에 의한 냉각이 골 치유에 미치는 영향에 관한 연구

이은영,신영진,이의석 원광대학교 치과대학 학생회 1992 學生學術誌 Vol.1 No.1

The application of recently developed rotary instruments to oral and maxillofacial surgical procedures has interrupted the healing process by affecting the temperature rise during drilling the bones. To evaluated the effects of healing process on the rabbit's calvarial defects, we have drilled the 6 holes on the calvarial bone resulting in three groups respectively according to 38, 300 and 20000 rpm, which divided into another two different groups operated under saline irrigation, and others not. Each specimen was sacrified at 3 days, 1, 2, 4, and 6 weeks post-operatively and routine fixation, Hematoxylin & Eosin stains and examined under light microscopic findings. The obtained results were as follows; 1. In each rpm, the healing processes of the saline irrigation groups were faster than those of no saline irrigation groups. 2. The lower the rpm of rotary instrument was, the faster the healing process. 3. In groups of using rotary instrument below 20000 rpm, there was appeared the good healing process that was operated under the low rpm with saline irrigation.