초등학생에서 인두배양과 항-OF 항체 보유율

정현주,김선주,김윤정,맹국영,정현주,김선주,김윤정,맹국영 대한임상병리학회 1998 대한임상병리학회지 Vol.18 No.3

제7차 교육과정의 과학교과서 지질단원에 대한 연계성 분석

윤성효,박기현,고정선 부산대학교 사범대학 과학교육연구소 2005 科學敎育硏究報 Vol.32 No.-

Using the task analysis technique, this study analyzes the contents of study and inquiry activities of geo-science units in twelve textbooks in total, which include eight elementary level textbooks from the third to sixth grades, three middle school level textbooks, one high school level science book. After choosing several main concepts, this paper analyzes the connection and hierarchy among them and presents the hierarchical structure as a diagram. The conclusions drawn from this study are as follows: First, from the analysis of studying content on geo-science unit, in the science education content from e third to tenth grades, the articulation of the major concepts, such as the inner part of the earth, rocks, plate tectonics, volcanic activities and earthquakes, layers and fossils, and gen-structure, are well associated with one another; on the other hand, unnecessary repetition and discontinuation appear in the mineral and gen-history sections. Overall, from simpler subjects, such as those related to the daily life, to the more complex scientific ones, the connection of contents is well maintained, which corresponds to the principle of organizing contents in the 7th curriculum. Second, the proportion of inquiry activities from analyzing inquiry content relating geo-science, is as follows: at the elementary school level, a total of thirty-one inquiry activities composed of observation (51.6%) and experiment (19.4%); at the middle school level, a total of twenty-seven inquiry activities consisted of data analysis (47.1%), experiment (25.9%) and observation (18.5%); at the high school level, these comprised data analysis (47.1%), discussion(17.6%), and follow-up (11.8%). Such findings show that while elementary schools focus on the observation of geological phenomena around us, middle schools on the data analysis, experiment, and observation, and high schools on particularly on the data analysis. Third, one of the important principles of the seventh curriculum is to compile textbooks in order to maintain the articulation between contents accordingly from the third grade to the tenth grade. The seventh curriculum emphasizes teaching and learning according to this code, and this paper presents the hierarchical structure as a diagram showing the flow among main learning points, It would contribute to improve instruction of science teachers in elementary, middle and high schools by helping to fully understand the hierarchical structure of the geo-science unit. therefore It will facilitates the application and settlement of the seventh curriculum.

고등학교 지구과학Ⅱ 교과서의 ‘화성암의 조직’에 대한 내용 분석

고정선,윤성효,한종수 부산대학교 과학교육연구소 2007 교사교육연구 Vol.46 No.2

이 연구는 7차 고등학교 공통과학 교과서의 내용 중 화성암 암석의 조직 개념에 대한 본문진술과 제시된 그림 및 도표들을 분석하고 오개념 유발과 관련하여 문제점을 지적하고 그 개선방안을 모색하였다. 과학교과서의 개념진술이 정확하지 않아 학습자들에게 오개념을 유발하거나 재강화할 가능성이 있는 여러 진술문을 발견하였고 학생의 과학적 개념형성에 부적절한 그림이나 도표들도 발견되었다. 이들은 화성암 조직 분류체계의 기준의 혼란에 관련된 것들이다. 이들 개념진술을 대체할 개선방안들을 제시하였다. The purpose of this study is to analyze the seventh curriculum textbooks of high school Earth Science-II courses in relation to the igneous rock texture concept and find incorrect descriptions of that concept and then suggest some improved schemes. Some incorrect descriptions, pictures and tables on the igneous rock texture concept were found in texts. They might contribute to forming and/or reinforcing misconceptions about the confusion of criterion about the igneous rock texture. Therefore some improved schemes were suggested.

부산 지역의 야외 지질 학습 자료 개발과 그 효과

장정일,고정선,윤성효 부산대학교 사범대학 과학교육연구소 2002 科學敎育硏究報 Vol.29 No.-

Learning materials for the field geological practices along the level-differentiated inquiry learning that considered learning ability of students were developed, and the effects of self-directed field geology program on the learning achievements and self-directed learning characteristics tried to examine. As for the field geological learning sites, the regions chosen Dadaepo and Songdo area in the southern part of Busan city, due to fresh outcrops and accessibility for the students. As for developed learning materials, it is considered to help in a learning achievements and self-directed learning ability.

학국에서 심방세동의 임상양상에 관한 연구

이선미,조정휘,홍순조,최윤식,안신기,김성순,김영훈,김윤년,조정관,차태준,김유호,최기준,김준수,이상민,신동구 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.5

해외여행상품구매에 있어서의 라이프스타일과 구매행동유형

윤선희,박정아 문화관광연구학회 2000 문화관광연구 Vol.2 No.4

This paper used psychological variables to understand outbound tourists' purchase behavior on life-style and purchase-style. The purpose of this study is to analyze lifestyle and purchase-style types of outbound tourists. Also it is to see if there is any relationship between life-styles and purchase styles. The research Method includes literary studies and empirical studies. Using 240 questionnaire respondence of outbound tourists, author conducted factor and cluster analysis with one-way ANOVA analysis. The results are as follows. First, the segment-markets according to the life-styles of outbound of tourists turned out to be external/achivemental, indivisualistic and traditional types. Second, purchase-style types of outbound tourists showed advertisement-purchase, safe-purchase, practical-purchase and loyal-purchase. Third, it reveals that there is difference between purchase styles and life styles. In conclusion, purchase-style variable as well as life-style one counts very usefully to be aware of the purchase behavior of outbound tourists.

진주지역에서 연쇄구균감염후 사구체신염의 재유행 : 최근 10년간의 임상적 고찰 Clinical Review of Recent 10 Years

김선주,김윤정 대한감염학회 1998 감염 Vol.30 No.6

목적 : 최근 구미에서 류마티스열이 재유행하고 A군 연쇄구균의 침습성 감염이 증가하고 있다. A군 연쇄구균 감염의 비화농성 후유증의 하나인 PSAGN이 재유행하는지 살펴보기 위해 진주지역에서 PSAGN의 발생 빈도를 조사하였다. 방법 : 1988년 1월부터 1998년 8월까지 경상대학교병원에 입원한 환자 중 PSAGN으로 진단받은 90명의 의무기록을 후향적으로 조사하여 PSAGN의 연도별 발생율과 환자들의 임상적 특성 및 검사 결과를 살펴보았다. 결과 : PSAGN의 발생빈도는 1993년까지 점차 감소하여 1993년에는 0.09%이었다가 1994년부터 다시 증가하였는데, 특히 1996년에는 1.83%로 유의하게 증가하였다(P<0.01). 월별로 보면 10월부터 1월까지 주로발생하여 전체 발생율의 64.4%를 차지하였다. 증상은 부종 78.9%, 육안적 혈뇨 65.6%, 핍뇨 22.2%, 발열이 16.7%에서 있었고, 내원당시 혹은 입원 중에 고혈압이 나타난 예는 28.9%이었다. ASO 증가가 92.0% (80/87)에서 있었고, C3와 CH50의 감소는 각각 94.4% (85/90)와 93.2% (41/44)에서 나타났다. 결론 : PSAGN의 발생은 1993년까지 감소하였지만 1994년 이후 다시 증가하는 추세임을 알 수 있었다. PSAGN의 재유행이 한 지역에 국한된 현상인지 전국적인 현상인지에 대한 신속한 조사가 필요하다. PSAGN의 원인균을 규명하기 위해 A군 연쇄구균에 대한 혈청학적 연구 등 역학적 조사가 필요하며, 비화농성 후유증을 예방하기 위해 A군 연쇄구균 인두염에 대한 적절합한 항생제 치료가 요구된다. Background : Rheumatic fever (RF) or streptococcal invasive disease have surged in developed countries recently. Incidence of poststreptococcal acute glomerulonephritis (PSAGN), a sequelae of group A streptococci (GAS) infection was investigated to evaluate the resurgence of PSAGN in Chinju. Methods : Medical records of 90 patients with PSAGN from January 1988 to August 1998 were reviewed retrospectively. Annual incidence, clinical characteristics, and laboratory findings were analyzed. Results : Annual incidence of PSAGN decreased until 1993, to as low as 0.09%, but started to increase in 1994 and became significantly high (1.83%) in 1996 (p<0.01). Most (64.6%) of PSAGN cases occurred from October to January. Major symptoms were edema (78.9%), gross hematuria (65.6%), oliguria (22.2%), and fever (16.7%). Hypertension was observed in 28.9% during admission. Increase of ASO were observed in 92.0% (80/87), decrease of C3 and CH50 in 94.4% (85/90) and 93.2% (41/44), respectively. Conclusion : Annual incidence of PSAGN decreased until 1993, but increased from 1994. Whether this resurgence of PSAGN is merely regional or part of a national epidemic should be investigated.

연령별 Antistreptolysin O 분포 및 정상치

김선주,정명아,정현주,김윤정,맹국영 대한감염학회 1998 감염 Vol.30 No.4

배 경 : ASO 검사는 S. pyogenes 감염과 류마티스열이나 급성 사구체신염 등 후유증을 진단하는데 매우 유용하다. ASO 정상치는 연령에 따라 달라지는 것으로 알려져 있으므로, 단회의 ASO 결과를 올바로 해석하기 위해서는 같은 지역의 동일한 연령의 정상치를 알고 있어야 한다. 방 법 : 저자들은 진주지역 학동기전 아동 (162명), 초등학생 (436명)과 성인 (231명) 세 군에서 ASO 정상치와 분포를 살펴보았다. 연쇄구균 감염 증상이나 징후가 없는 진주 지역 주민들을 대상으로 혈청내 ASO치를 자동화학분석기 (Cobas Mira, Roche)와 비탁기 (Behring Nephelometer 100 Analyzer)를 이용하여 정량 분석하였다. 결 과 : 학동기전 아동, 초등학생 및 성인에서의 평균 ASO치는 각각 71 IU/mL (표준편차 107), 285 IU/mL (표준편차 246) 및 80 IU/mL (표준편차 64) 이었고, 정상상한치는 각각 131 IU/mL, 433 IU/mL, 136 IU/mL 이었다. 결 론 : ASO 정상치 및 분포는 각 연령군에 따라 크게 다르므로, ASO 정상치는 연령에 따라 다르게 설정되어야 할 것이다. A군 연쇄구균 감염은 학동기전 아동이나 성인에서는 매우 드문 반면, 초등학생에서는 빈번함을 알 수 있었다. Background : Antistreptolysin O (ASO) is very useful as an indicator of recent streptococcal infection and its sequelae, such as rheumatic fever and acute glomerulonephritis. Becuase the upper limit of normal (ULN) value of ASO varies according to age, the ULN value of ASO in an area should be evaluated to accurately interpret single ASO levels of patients. Methods : The ULN value and distribution of ASO concentrations were investigated in three age groups of preschool children (N=162), elementary school children (N=436), and adults (N=231) in Chinju. ASO concentrations were measured quantitatively by autoanalyzer or nephelometer from sera of healthy population in Chinju who had no symptoms or signs of streptococcal infections. Results : The mean (±SD) ASO concentrations were 71 (±107) IU/mL, 285 (±246)IU/mL, and the UNL value of ASO concentratios were 131IU/mL, 433IU/mL, and 136 IU/mL in each group of preschool children, elementary school children, and adults, respectively. Conclusion : The distributio and ULN value of ASO concentrations varied according to age group. The ULN value of ASO concentrations should be set differently according to the patient's age. Group A streptococcal infections might be quite common in elementary school children, while very rare in preschool children or adults.

부산시 고등학생들의 환경에 대한 인식정도와 영향요인 분석

최인영,윤성효,고정선 부산대학교 사범대학 과학교육연구소 2004 科學敎育硏究報 Vol.31 No.-

The purpose of this study was to identify the degree of recognition of the high school students about environmental and influential factors on it, selecting two regular schools and three vocational schools among the high schools in Busan area, questionnairing one class in the 10th, 11th, 12th grades of each school and analyzing the result. The result of analyzing the degree of knowledge, practice and recognition of seriousness concerning environment according to grade and gender is that the significant difference has been found in the degree of practice. The result of analyzing them according to maternal academic background is that the significant difference has been found in the degree of knowledge and a living standard and the style of housing have no effect on the environmental education, In the survey according to family style, it is shown that the students 'who live with their parents' recognize the seriousness of environment more. In the survey according to the experience of having the subject 'environment' in their school curriculum or not, it is shown that the significant difference has been found in the degree of knowledge. As the source of information on environment, mass media such as TV, magazines and newspapers have a great impact on the students. As the significant difference has been found in the degree of knowledge, practice, the recognition of seriousness from the viewpoint of the analysis on the survey according to the degree of the recognition on the necessity of the environmental preservation, it is shown that the more the students feel the necessity of environmental preservation, the higher the degree of knowledge, practice and recognition of seriousness on environment becomes, In the survey according to the kind of school, the significant difference has been found in the degree of knowledge, In the survey according to the degree of maternal concern on environment it is shown that the more concerns the mothers have, the more the students put what they learn into practice, In the survey according to the kinds of school, the significant difference has been found in the degree of knowledge. As the result of multiple regression analysis is summarized as below. 1. The variables influencing the environmental knowledge are the experience of having the class, 'environment', the recognition of the necessity of the environmental preservation and maternal academic background. 2. The elements influencing the degree of recognition of seriousness about environmental contamination are gender, the experience of having a class, 'environment' or not and the necessity of the environmental education. 3. The elements influencing the degree of practice are grade, information on environment, and maternal concern.

비소세포 폐암 환자의 이차 치료로서 Gemcitabine과 Vinorelbine 혼합 요법의 효과

장필순,강현모,이정은,권선중,안진영,이연선,정성수,김주옥,김선영 충남대학교 암공동연구소 2006 암공동연구소 업적집 Vol.5 No.

Background : Both gemcitabine and vinorelbine are effective anticancer drugs with mild toxicity on non-small cell lung cancer, and monotherapy of these drugs are effective as a second-line chemotherapy. The aim of this trial was to assess the response and toxicity of a combination of gemcitabine and vinorelbine in patients of previously treated for non-small cell lung cancer. Materials and Methods : 24 patients, initial stage III A/B,IV and previously treated with platinium and taxane based regimens, were enrolled from June 2000 to March 2004. The regimens consisted of vinorelbine 25mg/㎡ followed by an infusion of gemcitabine 1000mg/㎡ on day 1 and day 8 every three weeks. This course was repeated more than twice. Results : Twenty-four patients were analyzed for the response, survival rate, and toxicities. The overall response was 17% with a complete remission rate of 4%. The median time-to progression (TTP) was 3.1 months (95%, CI l-10months), and the survival time was 8.2 months (95%, CI 1-23 months). The grade 3/4 toxicities encountered were neutropenia (12.5%), anemia (0%), thrombocytopenia (0%). Non-hematological 3/4 toxicities were not observed. Conclusion : A combination of gemcitabine and vinorelbine in patients previously treated for non-small cell lung cancer provides a relatively good response rate, and a low toxicity profile. However, further study will be needed to confirm its effectiveness. (Tuberc Respir Dis 2005; 58: 344-351) 배경 : Gemcitabine, paditaxel, docetaxel, vinorelbine, ir-rinotecan 새로운 항종양제의 출현으로 일차 치료의효과가 증대 되고 있고 재발시에도 좋은 신체 활동도를 보이고 있어서 이차 치료의 대상군도 늘어나는 효과를 보이고 있다. 치료의 필요성은 증대 되고 있지만 현재까지 표준 치료가 확립되지 않은 상황에서 Gem-citabine과Vinorelbine모두 독성이 강하지 않아서 혼합 요법이 가능한 장점이 있고 비소세포 폐암에 대한효과도 입증이 되어있어서 본 연구는 반응이 없거나 반응을 보인후에 재발된 진행된 비소세포 폐암에 ge-mdtabine과 vinorelbine 흔합 요법을 시행하여서 치료 반응률과 생존율 그리고 부작용을 평가하였다. 대상 및 방법 :2000년 6월부터 2004년 3월까지 충남대학교병원에내원하여 진행성 비소세포 폐암 IIIA/IIIB, IV로 진단을 받고 일차 항암화학요법치료를 받은 환자중에 초기 치료에 반응이 없거나, 치료에 반응이 있었으나 병이 진행된 환자로 추적 관찰 기간이 6개월 이상인 환자를 대상으로 생존율과 반응률 그리고 독성을 분석하였다. 결과 : 총 치료 반응률은 17%. 반응 유지기간의 중앙값은 3.1개월(1-10개월)이었고 생존기간의 중앙값은 8.2개월 (1-23개월) 그리고 1년 생존율은 35%였다. 항암화학요법에 의한 독성은 3도 이상의 중성구 감소가 12%, 오심과 구토가 12.5% 였다. 결론 : 일차 치료에 반응이 없거나 재발한 비소세포 폐암환자의 이차 치료로 gemcitabine과 vinorelbine 혼합요법은 효과적이라고 생각되며 향후 3상 연구를 통한다른 약제와의 비교 연구가 필요하다고 생각된다.