분자역학적 방법을 이용한 부산시내 대형건물 냉각탑수의 레지오넬라균의 형별 분류

김정만,정석훈,서대영,박은희,송은주,최재철,이은엽,장철훈 대한임상미샐물학회 2004 Annals of clinical microbiology Vol.7 No.1

Modulation of Gene Expressions and Enzyme Activities of Methionine Sulfoxide Reductases by Cold, Aba or High Salt Treatments in Arabidopsis

Oh, Jee-Eun,Hong, Suk-Whan,Lee, Yunsook,Koh, Eun-Ji,Kim, Kideok,Seo, Youngwon,Chung, Namhyun,Jeong, Moonsoo,Chang,Chang, Cheolseong,Lee, Byoungcheon,Kim, Kyoung Heon,Lee, Kwangwon,Lee, Hojoung 생명자원연구 2005 생명자원연구 Vol.13 No.-

보철물 절삭시 수종의 치과용 절삭기구와 냉각제의 효율성에 관한 연구

정은주,양홍서 전남대학교 치과대학 1996 전남치대논문집 Vol.8 No.1

The purpose of this study was to evaluate effects of dental cutting instruments and coolants to temperature changes of pulp chamber and to cutting weights. To evaluate effects of dental cutting instruments, the experimental groups were devided into 16. Four restorative materials (gold, base metal, resin, porcelain) were grinding with 4 cutting instruments(high speed diamond point, high speed fissure bur, low speed stone point, low speed rubber point). To evaluate effects of coolants, 16 groups were devided into 3 subgroups Group A : no use of coolant Group B : use of air coolant Group C : use of water-air spray coolant The results were as follows : 1. In kinds of coolants, temperature changes were shown in such order as group A, group B, group C. There was statistically significant difference between each group(p<0.05). Cutting weights were shown in such order as group C, group B, group A. There was statically significant difference between group C, B and A(p<0.05). 2. In kinds of cutting instruments, temperature change of diamond point as highest and temperature changes of high speed groups were higher than those of low speed groups. Cutting weights of fissure bur was highest and cutting weights of high speed groups were higher than those of low speed groups. 3. In kinds of materials of specimens, temperature change of base metal was highest and there were statistically significant difference between gold, base metal and resin, porcelain(p<0.05). Cutting weight of gold and base metal were higher than those of resin and porcelain. 4. The surface of specimen of group C, specially in use of high speed cutting instrument, showed less small particles than group A, B in SEM evaluation.

산란계에 투여된 플루오로퀴놀론계 합성항균제의 계란내 이행 잔류 연구

서계원,이재일,이채용,김은선,이정치 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.4

In the past few years the use of four fluoroquinolones such as of ofloxacin(OF), norfloxacin(NORE), ciprofloxacin(CIP), enrofloxacin(ENR) in veterinary practice has increased. The aim of this study was to determine the elimination of fluoroquinolones into eggs, by intramuscular injection of laying hens(2.5mg of ENR/kg, 5mg of CIP/kg, 5mg of NOR/kg, 5mg of OF/kg). The treatment of fluoroquinolones was carried out in 3 stages with 9 laying hens (Isabrown), with mean weight 1.8kg, which were housed in individual cages. Four fluoroquinolones were administered to 9 laying hens through intramuscular injection at 1 day, 2 days, 5 days trial respectively. Sample (Albumen, Yolk, Whole egg) were analysed by high performance liquid chromatography (HPLC) with a fluorescence programmable detector and matrix solid phase despersion (MSPD) extraction. Residues of fluoroquinolones were much higher in the yolk than in the albumen. Detectable residues persisted for 12 days, 14 days, 16 days, respectively, in albumen and yolk after the injection was discontinued. The increase of the fluoroquinolones concentration in yolk was very rapid and reached a plateau after 3 days of dosing. In albumen, the fluoroquinolones concentration increased during intramuscular injection. As soon as the injection was discontinued, residues decreased in the albumen and the yolk.

Fountain Effect의 이해를 위한 실험 장치의 개발 및 적용

서은미,정기주,이춘우 공주대학교 사범대학 과학교육연구소 2000 과학교육연구 Vol.31 No.1

아래 부분이 물에 잠겨 회전하는 물체에 나타나는 fountain effect를 이론적으로 분석하고 실험 장치를 만들어 이를 확인하였다. We analyzed theoretically about the fountain effect which a rotating metal-sphere shows on water and comparing to the experimental results.

TNF-α 유전자형과 방광암과의 관계

정필두,김은정,엄민식,서정원,윤석중,김종석,이상철,김원재 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적: TNF-α는 일부 종양의 종양화 과정과 관련이 있는 것으로 알려져 있다. 본 연구는 TNF-α 발현에 영향을 미치는 TNF-α 촉진자 -308 부위의 유전적 다형성이 방광암과 관련이 있는지 유무를 알고자 시행하였다. 대상 및 방법: 유전자 분석을 위하여 환자 113명 및 대조군 109명으로부터 혈액을 채취하여 genomic DNA를 분리한 후 PCR-RFLP 및 direct DNA sequencing을 통하여 TNF-α유전자의 다형성을 조사하여 방광암의 발생, 병기 및 분화도와 비교 검토하였다. 결과: TNF-α 촉진자 -308 부위의 유전형은 대조군에서는 GG형이 83.5%(90례 및 GA형이 16.5%(19례)로 관찰되었으며 AA형은 없었다. 환자군에서는 GG 형이 85.4%(97례), GA형 및 AA형은 각각 13.1%(15례)및 0.8%(1례)에서 관찰되었다. 두 군 모두에서 GG형이 가장 많이 나타났으며 다음으로 GA형을 보이고 AA형은 1례의 방광암 환자에서만 관찰되었다. -308부위의 경우도 두 군 사이에 유전자형의 차이는 없었다(p=0.259) 분화도별 분포를 보면 grade I이 20례, grade II가 49례, grade Ⅲ은 34례였고 병기별로 표재성인 경우가 90례였으며 침윤성은 14례였다. 분화도가 나빠질수록 GA형이 증가하였다(p=0.04). 그러나 병기와 TNF-α promoter -308부위의 유전자형 사이에는 유의한 상관 관계가 없었다(p=0.123). 결론: 방광암 환자의 혈액에서 GA genotype이 관찰되는 경우, 분화도가 나쁠 가능성이 매우 높기 때문에 좀 더 적극적인 치료와 세밀한 추적관찰을 함으로써 방광암으로 인한 사망과 암의 진행을 예방할 수 있을 것으로 기대한다. Purpose : Tumor necrosis factor-alpha (TNF-α) is involved in tumorigenesis of several cancers as an endogenous tumor promoter. The purpose of this study was to investigate whether genetic polymorphism of TNF-α promoter region (-308) was associated with human bladder tumor. Materials and Methods: The DNA from 113 and 109 respective blood samples of bladder tumor Patients and control group was analyzed by PCR-based restriction fragment length polymorphism (RFLP) and direct DNA sequencing methods to characterize the genetic polymorphism of -308 promoter region of the TNF-α gene in bladder tumor patients. We compared the association of bladder tumor with genetic Polymorphism of TNF-α promoter region(-308) in relation to the stage, grade, recurrence and progressio. Results : Eighty-six percents(97/113) of bladder tumor patients and 83.5% (90/109) of control group showed genotype GG at -308 region of TNF-α. Difference in genetic variations of TNF-α promoter (-308) did not exist between bladder tumor patients and control group(p=0.259). Tumor grade was significantly related to the GA genotype (p=0.04). The higher is the grade in bladder tumor, the more frequent was the GA genotype. Tumor stage, recurrence and progression were not significantly associated with genetic polymorphism of TNF-α promoter region (-308). Conclusion: The GA genotype of TNF-a promoter region (-308) had a significant impact on TNF-α production and was related to higher grade tumor compared to GG genotype. TNF-α serum levels in bladder tumor patients were significantly higher than controls. These data suggested that TNF-α might involve the tumorigenesis of the bladder rather than treatment or prevention of bladder tumor.

인터넷카페 게시판에 나타난 메이크업에 관한 내용 분석

서정희,이은정 울산대학교 2004 생활과학논문집 Vol.6 No.1

이 논문은 인터넷카페 게시판에 올려진 게시물들의 세부내용 중 메이크업 테크닉에 관한 내용과 유행 메이크업의 경향을 분석하여 메이크업에 관한 주제유목별 하위영역은 어떠한가를 살펴보고, 여성들이 주로 메이크업에 관해 어떠한 정보를 인터넷상에서 공유하고 있는지를 알아보고 그 내용들을 분석하였다. 인터넷 카페 게시판에 올려진 게시물에 나타난 메이크업을 관한 분석한 결과 다음과 같은 결론을 내릴 수 있다. 가장 많은 빈도를 나타내는 주제 유목으로는 눈에 관한 주제였고, 다음으로는 베이스메이크업, 입술유목, 마지막으로 얼굴형 유목아 가장 적은 빈도를 나타냈다. 그 내용들을 살펴보면 첫째, 눈 유목에서는 아이새도우에 가장 많은 관심을 가지고 있음을 알 수 있고, 여성들이 바라는 이상형의 눈인 커 보이고, 속눈썹이 길고 자기의 결점을 감출 수 있는 테크닉을 바라는 것으로 나타났다. 둘째, 베이스메이크업은 가장 피부색에 가깝게 화장을 하지 않은 듯한 느낌을 주기 위해 신경을 많이 쓰는 부분으로 나타났다. 셋째, 입술 유목에서는 맑고 투명함, 촉촉한 입술을 표현하는 립글로스에 치중되어 관심을 보여지고 있었고, 요즘 트렌드인 투명 메이크업과도 연관을 지을 수 있다. 마지막으로 얼굴형 유목에서는 요즘 흔히들 말하는 미인형 즉, 작고 갸름한 달걀형 얼굴을 바라고 있는 것을 반영하듯이 얼굴 작아지는 쉐딩(shading)표현으로 음영을 주어 입체감 있게 얼굴형을 커버하는 테크닉이 설명되어 있다. 그러므로 여성들은 자기의 결점을 감출 수 있는 메이크 업 테크닉과 서구형의 입체적인 얼굴형을 닮아가려는 것으로 보여진다. This paper is analyzed for methods and trend of make-up on the web board, including sub area of each topic in make-up, how to share an information about make-up in the internet between female user and analyzing that contents. I can conclude after analyzing articles about make-up on the web board in internet. The frequent field of topic is eye and next one is base make-up, lip and less frequent item is face. To investigate of contents First, they are interested in eye-shadow very much which is skill of make bigger eye, longer eye lashes and concealing their flaw through make-up. Second, they attention on base make-up similar with skin color like dose not make-up on the face. Third, they are interested inusage of lip-glosse for moisturing lips and it also connects with make-up of transparency. Finally, they want to be type of “pretty woman” such as small and slim face, so it can be by “shading” skill, for expressing contrast. Therefore, woman want to conceal their flaw by some of skill and want to be face of western type.

退行性關節炎 韓方治療에 對한 最近 硏究 動向 : 臨床硏究 方法論을 中心으로 Herbal Medicines in the Treatment of Osteoarthritis in Pubmed and Chinese Medical Journals

서병관,류성룡,이송실,허정은,백용현,이재동,최도영,조윤제,김남재,박동석 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Objective : The aim of this study was to review systemically clinical trials on the effectiveness and safety of herbal medicines in the treatment of osteoarthritis. Methods : Computerized literature searches were carried out on seven electronic databases, and hand-searching on some chinese medical journals in library of Kyung Hee Medical Center. Trial data were extracted in a standardized, predefined manner and assessed independently. Results : 1. Thirty reports of clinical trials and two reports of meta-analyses concerning herbal medicine were collected and reviewed Among these reports three medical herbs were applied as topical medicine and others as internal medicine. 2. The western studies established NSAIDs or placebo as their control group. Five chinese reports established formulated herb pill(Ruanshnagshenjin pill) as their control group and Six did not establish a control group at all. 3. ACR was the most highly used diagnostic criteria in the western studies while the Chinese used their official criteria established by their government or the criteria of their text books. 4. 20 reports chose the Lequesne functional index, SHAQ, WOMAC OA index, AIMS, and their own unique scoring system as the criteria of analysing the effect. Others chose clinical symptoms, articular functions, and lab finding as their criteria. 5. 7 single herbs and 19 formulated herbs were studied. Among the formulated herbs, Achyranthes japonica was studied in 10 of the studies and Angelica gigantis Radix in 8, making them the most often studied herbs among the studies.

회분식 활성슬러지 반응기에 의한 염분폐수의 생분해성 평가

서정범,김민종,배지은,이상명 안양대학교 산업기술연구소 2001 自然科學硏究 Vol.8 No.-

생물학적 처리가 가능한 염분 농도의 범위를 알아보기 위하여 회분식 활성슬러지 반응기에 합성폐수를 주입하여 실험을 수행하였다. 연구결과 폐수중의 염분 농도가 20,000mg/L 이상이 되면 폐수처리 효율이 떨어지는 것을 알 수 있었다. 염분 농도가 10,000mg/L 이하 일때는 회분식 활성슬러지 반응기에 의한 TOC 제거효율이 85% 이상인 반면, 염분 농도가 20,000mg/L 이상일 때는 TOC 제거효율이 80% 이하를 나타내었다. 또한 생물반응조내의 MLSS 농도에 따라 질산화 정도가 다름을 알 수 있었다. To determine the salt concentration range which wastewaters be treated by biological processes, experiments were performed by feeding activated sludge batch reactor with synthetic organic wastewater. Results of the research showed that wastewater treatment efficiencies deteriorated as salt concentration of wastewaters became above 20,000mg/L. The TOC removal efficiencies of activated sludge batch reactor were above 85% when the salt concentration were below 10,000mg/L. On the other hand, when the salt concentration were above 20,000mg/L, the TOC removal efficiencies were below 80%. It was also found that nitrification was affected by the MLSS concentration in the reactors.

상업건축물의 파사드 주조색과 전면간판의 색채배색에 관한 연구 : 대구시 상업지역을 중심으로

서지은,김정재 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

The purpose of this study is to investigate relationships between dominance color of facade in commercial building and color of front signboard and images and degree of satisfaction of each type. The results of the analysis were as follows : 1) Similarity Harmony is mainly used among coloration. 2) In similarity harmony, There are positive response for image of arranged. In opposition harmony, there are positive response for image of catch sight. In achromatic color harmony, there are positive response for image of refined. In ton harmony, there are positive response for image of light. 3) Image of refined effects of degree of satisfaction in coloration.