농어촌 인구 정주에 관한 환경 계획적 연구

정성찬,이길영 大田大學校 環境問題硏究所 2002 환경문제연구소 논문집 Vol.6 No.-

The settlement of population in agricultural areas helps to prevent the influx of agricultural population to metropolitan areas and also contributes to improving residential environments of large cities. Constituting a major pillar to support balanced development of a nation, it can be said to be the key task in regional planning. Recently, Korean agricultural society has gone through a tremendous change. The economic policy of urbanization and industrialization enforced in the 1970's resulted in the concentration of industries and economies mostly in cities, which inevitably led to the phenomenon of so-called "leaving countries for cities." This indicates the outflow of agricultural population from countries into cities. As a result, the development of agricultural regions has slowed down, with the population decreasing and the community becoming empty, in contrast to urban areas. Consequently, agricultural areas are facing a crisis, and it is hard even to maintain them as residential areas. Furthermore, the wide regional gap between cities and agricultural areas derived from the process of urbanization and industrialization is recognized as a big barrier to the efficient use and balanced development of the land of the nation. Therefore, plans of rearrangements of residential environments in the agricultural areas are emergingas an urgenttask, both in revitalization of decreasing agricultural areas and in balanced developmentof the national territory. However, academic investment or developmental policies up to now have been mostly concentrated on cities. Matters of agricultural areas, thus, have been neglected as secondary problems to those of cities. It is essential to view the question of the settlement of agricultural population from various perspectives and to have academic involvement. Yet, the settlement of population, the result of movement, is a very complicated phenomenon originated in the relationships between residents, the subjects of settlement, and the surrounding regional circumstances. These phenomena vary according to the behaviors and attitudes of the residents. And the degrees of satisfaction of the residents differ depending on each individual's value system. Therefore, the attempt to establish the settlement of the agricultural population can be seen in this context. It is the biggest mission, then, to simultaneously examine both aspects, the aspect regarding regional environments and the aspect related to residents, the subjects of settlement. Finally, as mentioned before, it is necessary to note that the attributes and conditions are various both in a macroscopic level involving regions and in a microscopic level involving individuals as subjects of settlement. It is also necessary to investigate the perspectives from which the settlement in the agricultural regions is dealt with in the regional, environmental planning. Obviously, this issue needs be handled with external and internal analyses as it involves both the reality and the ideal of the residents' value system. Therefore, this study is not about simply restoring the past in regard to a series of problems with the settlement of agricultural population. This study aims to pursue the natural essence of agricultural areas in which new agricultural regions and cities can be integrated under the conditions of national territory, and at the same time, to deal with the agricultural areas as new space for settlement.

혈액투석 환자에게서 발생한 재생불량성 빈혈 1예

정지용,윤나라,강대웅,오종찬,장재현,선길홍,박경희,정종훈,김현리 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.1

Aplastic anemia is a disease characterized by pancytopenia in the peripheral blood and hypocellular bone marrow with the fatty infiltration. The causes of the acquired aplastic anemia were usually related to drugs and immune-related diseases. A 34-years old man was admitted due to general weakness. He has been going hemodialysis for 2 years because of end stage renal disease (ESRD) due to chronic glomerulonephritis. At admission, laboratory tests showed hemoglobin 6.2 g/dL, hematocrit 18.0 %, WBC 5,710mm (neutrophil 71.8%, lymphocyte 19.1%, monocyte 5.9%), reticulocyte 1.9%, platelet 93,000/mm, Fe 12.8 ug/dL, TIBC 204 ug/dL, ferritin 941.47 ng /ml, haptoglobin 0.72 g/L, vitamin B12 508.17 pmol/L, folate 24 ng/mL, total protein 6.54 g/dL, albumin 3.76 g/dL, Alk. pohsphatase 79 IU/L, AST 30.0 IU/L, ALT 39.7 IU/L, total bilirubin 0.57 mg/dl, BUN 79.4 mg/dl and creatinine 10.18 mg/dl. Peripheral blood smear showed the normocytic normochromic anemia with anisocytosis. Anemia was diagnosed but it was irresponsive to the recombinant human erythropoietin (EPO) and blood transfusion. In the bone marrow aspiration smear were there the hypoplastic myeloid and erythroid precursors. The bone marrow biopsy section showed the hypoplasia of all components (10-20%) and the fatty infiltration. We have experienced one case of the idiopathic aplastic anemia in a patient going through hemodialysis and we just report it with documentary records. 저자들은 혈액 투석 중인 환자에서 약물, 면역계 이상등의 원인을 발견할 수 없었음에도 재생 불량성 빈혈이 발생한 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례

선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

한국산 경천과(景天科) 식물에 관한 본초학적(本草學的) 연구

정종길 ( Jong Gil Jeong ),주정석 ( Jung Suk Joo ),최찬헌 ( Chan Hun Choi ),김정상 ( Jeong Sang Kim ),김재현 ( Chae Hyun Kim ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.3

Objectives: For the purpose of developing Korean herbalogy of the plants belonging to Crassulaceae in Korea, the literatures of the successive generations have been thoroughly investigated to prepare this article. Methods: The examined herbalogical books and research papers which published at home and abroad. Results: 1. There were totaled to 6 genera and 39 species in Crassulaceae in Korea and among them medicinal plants are 5 genera, 14 species, some 36% in total. 2. Sedum genus is main kind enough that it has 20 species among 39 species in the Crassulaceae, of which medicinal plants are 9 species. 3. The herb is the main medicinal parts of medicinal plants in the Crassulaceae which is used in 14 species. 4. According to nature and flavor of medicinal plants in the Crassulaceae, they were classified into neutral 12 species; sour taste 14 in the order. 5. According to meridian propism of medicinal plants in the Crassulaceae, they were classified into liver meridian 13 species. 6. According to the properties and principal curative action in the Crassulaceae, they were classified into drugs for detoxicant 19 species, drugs for styptic 18, drugs for detumescence 14 in the order. 7. The number of toxic species in the Crassulaceae was examined to be 3 species. Conclusions: There were totaled to 6 genera and 39 species in Crassulaceae in Korea and among them medicinal plants are 5 genera, 14 species, some 36% in total.

Engagement of CD99 Reduces AP-1 Activity by Inducing BATF in the Human Multiple Myeloma Cell Line RPMI8226

Gil, Minchan,Pak, Hyo-Kyung,Park, Seo-Jeong,Lee, A-Neum,Park, Young-Soo,Lee, Hyangsin,Lee, Hyunji,Kim, Kyung-Eun,Lee, Kyung Jin,Yoon, Dok Hyun,Chung, Yoo-Sam,Park, Chan-Sik 한국조명·전기설비학회 2015 한국조명·전기설비학회 학술대회논문집 Vol. No.

<P>CD99 signaling is crucial to a diverse range of biological functions including survival and proliferation. CD99 engagement is reported to augment activator protein-1 (AP-1) activity through mitogen-activated protein (MAP) kinase pathways in a T-lymphoblastic lymphoma cell line Jurkat and in breast cancer cell lines. In this study, we report that CD99 differentially regulated AP-1 activity in the human myeloma cell line RPMI8226. CD99 was highly expressed and the CD99 engagement led to activation of the MAP kinases, but suppressed AP-1 activity by inducing the expression of basic leucine zipper transcription factor, ATF-like (BATF), a negative regulator of AP-1 in RPMI8226 cells. By contrast, engagement of CD99 enhanced AP-1 activity and did not change the BATF expression in Jurkat cells. CD99 engagement reduced the proliferation of RPMI8226 cells and expression of cyclin 1 and 3. Overall, these results suggest novel CD99 functions in RPMI8226 cells.</P>

A Status of Technology and Policy of Nuclear Spent Fuel Treatment in Advanced Nuclear Program Countries and Relevant Research Works in Korea

Gil-Sung You,Won-Myung Choung,Jeong-Hoe Ku,Il-Je Cho,Dong-Hak Kook,Kie-Chan Kwon,Won-Kyung Lee,Eun-Pyo Lee,Dong-Hee Hong,Ji-Sup Yoon,Seong-Won Park 한국방사성폐기물학회 2007 방사성폐기물학회지 Vol.5 No.4

전세계 주요 원자력선진국들의 사용후핵연료 처리에 대한 기술 및 정책현황을 알아보고 향후 우리나라의 연구방향을 제시해 보았다. 재처리 정책을 가진 소위 핵연료주기 국가들은 최근 선진핵 연료주기기술에 기초한 새로운 사용후핵 연료 관리정책을 발표하였다. 그 정책은 사용후핵연료 내에 함유된 우라늄 또는 초우란 원소들을 재순환하고 고독성의 방사성 물질 및 장반감기를 가진 물질들을 소멸하거나 단반감기 원소로 변환하는데 초점을 맞추고 있다. 이러한 정책은 원자력의 자원 활용성을 높일 뿐만 아니라, 영구 처분할 고준위폐기물의 양을 감소시켜 궁극적으로 원자력의 지속가능성을 높여 준다. PUREX 방법에 기초한 습식재처리를 우선순위로 선택한 대부분의 국가들은 이 습식방법이 건식방법에 비해 실용화에 앞서 있음을 그 선택 의 근거로 든다. 그러나 습식방법은 건식에 비해 핵확산저항성 측면에서 더욱 민감하다. 왜냐하면 이 습식방법은 약간의 공정수정에 의해 순수 플루토늄을 회수 할 수 있기 때문이다. 반면에 아직까지 실용화 단계까지는 도달해 있지 않지만 고온 용융염을 사용하는 Pyroprocess와 같은 건식처리 방법은 순수한 플루토늄을 회수 할 수 없어서 핵비확산성 측면에서 유리하며, 제4세대 원자로로 고려되는 고속로의 핵연료주기 등에도 여러 가지 이점을 가지고 있다. 따라서 우리나라의 경우 현재 이 Pyroprocess에 대한 연구가 활발히 진행되고 있다. Status on the spent nuclear fuel management policy and R&D plan of the major countries is surveyed. Also the prospect of the future R&D plan is suggested. Recently so-called fuel cycle nations, which have the reprocess policy of the spent fuel, announced new spent fuel management policy based on the advanced fuel cycle technology. The policy is focused to transmute highly radioactive material and material having a very long half-life, and to recycle the Pu and U contained in the spent fuel. In this way the radio-foxily of the spent fuel as well as the amount of the high level waste to be eventually disposed can greatly be reduced. Most of countries selected the wet process as a primary option for the treatment of the spent fuel since the advanced wet process, which is based on the existing PUREX process, looks more feasible as compared with the dry process. The wet process, however, is much more sensitive in terms of proliferation-resistance compared with the dry process. The pure Pu can easily be obtained by simply modifying the process. On the other hand the pure Pu can not be extracted in the dry process based on the high temperature molten salt process such as a pyroprocess. Even though the pyroprocess technology is very premature, it has a great merit. Thus it is necessary for Korea to have a long term strategy for pursuing a spent fuel treatment technology with a proliferation resistance and a great merit for the GEN-IV fuel cycles. Pyroprocess is one of the best candidates to satisfy these purposes.

Chemo- and Bio-cascade Catalysis to Produce Plastic Monomers from Polyethylene Terephthalate

Jeong Chan JOO,Si Jae PARK,Kyoung Heon KIM,Dongyeop OH,Bong Keun SONG,Hyun Gil CHA,Bong Hyun SUNG,Young Joo YEON,Hee Taek KIM 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.4

DESIGN AND CONSTRUCTION OF AN ADVANCED SPENT FUEL CONDITIONING PROCESS FACILITY (ACPF)

GIL-SUNG YOU,WON-MYUNG CHOUNG,JEONG-HOE KU,IL-JE CHO,DONG-HAK KOOK,KIE-CHAN KWON,EUN-PYO LEE,WON-KYUNG LEE 한국원자력학회 2009 Nuclear Engineering and Technology Vol.41 No.6

KAERI has worked on the development of an advanced spent fuel conditioning process (ACP) since 1997. A hot cell facility, termed the ACPF, has also been developed. The ACPF consists of two air-sealed hot cells. The results of a safety analysis as part of the license procurement process stipulated by the Korean Government showed that the facility was designed safely. After its construction, an integrated performance test was performed. The results of this test confirmed that the facility satisfies the design requirements.

Biological Upcycling of PET (Polyethylene Terephthalate) into Value-added Chemicals

Jeong Chan JOO,Si Jae PARK,Kyoung Heon KIM,Bong Keun SONG,Hyun Gil CHA,Hee Taek KIM 한국생물공학회 2020 한국생물공학회 학술대회 Vol.2020 No.10

Interleukin‐15 enhances proliferation and chemokine secretion of human follicular dendritic cells

Gil, Minchan,Park, Seo‐,Jeong,Chung, Yoo‐,Sam,Park, Chan‐,Sik Blackwell Publishing Ltd 2010 Immunology Vol.130 No.4

<P><B>Summary</B></P><P>The germinal centre (GC) is a specialized microenvironment where high‐affinity antibodies are produced through hypermutation and isotype switching. Follicular dendritic cells (FDCs) are the stromal cells of the GC. The timely expansion and establishment of an FDC network is essential for a protective GC reaction; however, only a few factors modulating FDC development have been recognized. In this study, we report that interleukin‐15 (IL‐15) enhances human primary FDC proliferation and regulates cytokine secretion. The FDCs express IL‐15 receptor complexes for IL‐15 signal transduction as well as for specific binding. Moreover, the secretion of chemokines CCL‐2, CCL‐5, CXCL‐5 and CXCL‐8 was reduced by blocking IL‐15 signalling while the secretion of other cytokines, and the expression of CD14, CD44, CD54 (ICAM‐1) and CD106 (VCAM‐1) proteins remained unchanged. These results suggest that IL‐15 plays a crucial role in the development of FDC networks during GC reaction, offering a new target for immune modulation.</P>