http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Tunicate-mimetic nanofibrous hydrogel adhesive with improved wet adhesion
Oh, Dongyeop X.,Kim, Sangsik,Lee, Dohoon,Hwang, Dong Soo Elsevier 2015 ACTA BIOMATERIALIA Vol.20 No.-
<P><B>Abstract</B></P> <P>The main impediment to medical application of biomaterial-based adhesives is their poor wet adhesion strength due to hydration-induced softening and dissolution. To solve this problem, we mimicked the wound healing process found in tunicates, which use a nanofiber structure and pyrogallol group to heal any damage on its tunic under sea water. We fabricated a tunicate-mimetic hydrogel adhesive based on a chitin nanofiber/gallic acid (a pyrogallol acid) composite. The pyrogallol group-mediated cross-linking and the nanofibrous structures improved the dissolution resistance and cohesion strength of the hydrogel compared to the amorphous polymeric hydrogels in wet condition. The tunicate-mimetic adhesives showed higher adhesion strength between fully hydrated skin tissues than did fibrin glue and mussel-mimetic adhesives. The tunicate mimetic hydrogels were produced at low cost from recyclable and abundant raw materials. This tunicate-mimetic adhesive system is an example of how natural materials can be engineered for biomedical applications.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Biodegradable Plastic"s Applications and Fate in the Environment
Dongyeop Oh(오동엽) 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2
More than 300 million tonnes of plastic are produced each year. However, less than 10% of that is recycled. Biodegradable plastic is emerging as a material that can solve this problem. In this talk, I would like to introduce the application of biodegradable plastics developed in our laboratory: 1) food packagings, 2) face masks, 3) cosmetic microbeads. More importantly, we have studied the fate of biodegradable plastics when they spilled into the ocean and soil.
A biomimetic chitosan composite with improved mechanical properties in wet conditions
Dongyeop X. Oh,Dong Soo Hwang 한국당과학회 2012 한국당과학회 학술대회 Vol.2012 No.1
Chitosan is one of the most widely used structural polymers for biomedical applications because it has many favorable properties. However, one of the most critical drawbacks regarding the use of chitosan as a biomedical material is its poor mechanical properties in wet conditions. Here, we designed a method to improve the mechanical properties of chitosan in wet conditions and minimized the swelling behavior of chitosan film due to water adsorption by mimicking the sclerotization of insect cuticles and squid beaks, i.e., catechol-meditated cross-linking. The biomimetic chitosan composite film was prepared by mixing chitosan with L-3,4-dihydroxyphenylalanine (DOPA) as a catecholic cross-linker and sodium periodate as an oxidant. The catechol-meditated cross-linking provided a 7-fold enhancement in the stiffness in wet conditions compared to pure chitosan films and reduced the swelling behavior of the chitosan film. This strategy expands the possible applications for the use of chitosan composites as load-bearing biomaterials.