허혈성 심질환에 있어서 아데노신 급속 정맥투여후 관동맥압의 변화에 관한 연구

봉종대,오종용,배성한,신원용,김철현,이광희,최태명,현민수,김성구,권영주 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

Background: Adenosine interacts with A1 receptors present on the extracellular surface of cardiac cells, activating K+channels in a fashion. It produces coronary vasodilatation and AV nodal block. The half-time is one to six second and has ultra-short action. In ischemic heart disease, fractional flow reserve(FFR) can be achieved safely with intravenous adenosine infusions at a rate of 150㎍/kg/min which cause maximal coronary hyperemia. Purpose: We investigated the patients who have had ischemic heart disease(n=8). After adenosine intravenous administration(150㎍/kg/min), the effect cause maximal hyperemia of coronary artery. During peak maximal hyperemia, we reported clinical findings, coronary hemodynamics and electrocardiogram findings. Methods: After diagnostic coronary angiography and left ventriculography, catheter was advanced into the ostium of coronary artery. We investigated coronary hemodynamics such as systolic coronary artery pressure, diastolic coronary artery pressure, mean coronary artery pressure and heart rate. To assess the use of adenosine for determination of fractional flow reserve, hemodynamics and electrocardiogram were measured at basal state and during peak maximal hyperemia. Results: Symptoms developed 1.5-2 minute after adenosine intravenous administration and each symptom disappeared 2-2.5 minute after adenosine administration. Two patients represented asymptomatic appearance and six patients complained of flushing, chest pain, palpitation and headache. In eight patients with ischemic heart disease, 1.5 minute after venous administration of 150㎍/kg/min of adenosine, coronary artery pressure decreased and heart rate increased significantly. Conduction abnormalities after administration of 150㎍/kg/min of adenosine were transient 2nd degree AV block 2 cases(25%). Conclusions: Adenosine is a potent ultra short-acting vasodilator. Although coronary artery pressure decreased and heart rate increased and mild cardiovascular symptoms occurred after continuous infusion of 150㎍/kg/min of adenosine, it is useful as an agent for determination of fractional flow reserve.

혼파초지에서 질소시비수준과 방목율이 목초 및 육우생산에 미치는 영향

현봉수,김문철,김영호,송성언,이승협 제주대학교 농과대학 제주도축산문제연구소 1986 畜産論叢 Vol.1 No.1

Effects of N fertilizer levels and stocking rates on beef production in a mixed pastiire of orchard-grass, perennial ryegrass, tall fescue, red clover and alsike clover were studied using 3 levels of N fertilizer (50, 100 and 200 kg/ha) and 3 stocking rates (3,4 and 5 head /ha). The summarized results are the following; 1. Increasing nitrogen fertilizer on the mixed pasture increased dry matter yield and protein content(P<0.05) of the pasture species. The stocking rate did not influence either dry matter yield or protein content. 2. The percentage of pasture species increased and that of weeds decreased with increasing N fer-tilizer levels. lncreasing stocking rate from 3 to 5 heads/ha significantly influenced that of the other pastures and weeds. 3. Herhage intake per animal increased at the lower stocking rate, but total herbage intake per ha increased at the higher stocking rate, Increasing nitrogen fertilizer decreased herbage intake per animal , but slightly higher intake per animal was obserbed at 5 head stocking rate. 4. No significant difference in weight gain/ha was found among N levels and stocking rates ussd. Live weight gain per animal was greater at the higher N level and also at the louer stocking rate.

교통사고요소를 포함한 도로투자 우선순위 결정 : 대전광역시를 중심으로

성현영,장현봉 목원대학교 건축도시연구센터 2004 建築·都市環境硏究 Vol.12 No.-

There are several methods for deciding the priorities among many highway investments in Korea. But these methods have some weakness in procedure of evaluation and evaluation criteria. Moreover, priorities are much influenced by other factors, such as the will of decision-maker, the budget constraints and the tendency of political atmosphere. In the thesis, we make equal ranges for each evaluation items in order to minimize the errors caused by different ranges for each evaluation items. Also the traffic accident data were added to existing evaluation items. As a result, more reasonable procedure for deciding the priorities of highway investment are possible, using the existing traffic accident data.

조선후기 친족결합 양상 : 충청도 지역 족계를 중심으로 Focusing on a local kinship fraternity in Chungcheong-do

成鳳鉉 한국고문서학회 2002 古文書硏究 Vol.21 No.-

조선사회에 있어서 친족은 중요한 사회수단이며, 사회구성 요소의 하나이었다. 그런데 친족은 세대가 지나면서 자연히 확대될 수밖에 없고, 그렇게 되면 친족의 결속은 자연 소원하게 되었다. 이러한 친족을 결속하기 위하여 조선후기 유행하기 시작한 것이 族契이다. 조선후기 친족의 결속을 이해하기 위하여 충청도 지역에서 조사된 족계 자료에 나타난 몇 가지 양상과 족계유행의 배경을 살펴 보았다. 족계는 대종계와 소종계로 나뉘는데, 소종계는 봉사대상의 현손들이 入契한 경우이고, 대종계는 遠祖를 제사하기 위한 것이었다. 족계에는 친손, 외손, 서자, 서손 까지도 참여하였다. 그러나 17세기 이후부터는 외손의 참여가 점차 배제되었으나, 그럼에도 소수이기는 하나 조선후기까지 외손이 친족으로 참여하였다. 그리고 족계의 참여는 성인이며 호주이었으나, 미성년의 자손이 참여 하였고, 父子가 함께 참여하기도 하였다. 족계의 정기회는 일년에 봄과 가을에 하였고, 정기회 때에 묘제를 지내고, 講信會라 하여 '立議'를 익히게 하였다. 정기회에 불참자와 입의를 준수하지 않는 족계원에 대해서는 강력하게 처벌하는 조목을 두어 친족의 결속을 강화 하였다. 조선후기에 족계가 유행하게 된 배경은 첫번째로는 종법질서의 정착에 따른 제사의 일반화이고, 둘째로는 조선후기에 이르러 증가된 친족의 파별의 결속을 위한 것이었으며, 마지막으로는 조선후기에 戰亂, 仕宦, 婚娶 등으로 친족들이 여러 곳으로 분산 거주하게 되자 이를 결속하기 위하여 실시한 것이다. In Joseon, consanguinity was an important social unit and one of components of society. Therefore, a person was considered social individual simply and one of the clans he belonged to at the same time. At this point, we call clan consanguinity, who closely related to him in a family tree and lived with him in the same area, not referring to whole clan group to which he belonged. However, small consanguinity groups became larger and brought the decline of family bond as generations went by. The weakened bond of consanguinity needed a systematic tool to strengthen the solidarity in the Joseon society where consanguinity functioned as a social unit. The solidification of Sung Confucianist order in late Joseon also wanted consanguinity which centered on the agnate. From the reason of this necessity in late Joseon society, a kinship fraternity began to be popular. The following are the several aspects of consanguinity formation in late Joseaon through the documents on the kinship fraternity in Chungcheong-do after the seventeenth century. The kinship fraternity is divided into Daejong fraternity for distant ancestors and small-scale Sojong fraternity branching off from Daejong; the first is for holding a ceremony for the repose of ancestors before the great-great- grandparent, and great-great-grandsons organized the second. In the kinship fraternity, grandsons, grandsons of daughters, even sons by a concubine, and grandsons by a concubine participated. Although few grandsons of daughters participated in the fraternity with the society turning to agnate-centered after the seventeenth century, some of them joined in the kinship fraternity as a consanguinity even in late Joseon. In general, the person should be an adult and householder for joining the kinship fraternity. However, sons under age or father and son sometimes joined it. The regular meeting of the kinship fraternity was held twice in spring and fall a year, an ancestral rite was held before the grave in the meeting. After the rite, people read and acquired 'Ipui' (regulations of the fraternity) in a Gangsinhoi meeting to strengthen the bond of kinship. There was a provision to punish a member of the fraternity severely for not participating in regular meetings and not observing the regulations. This kind of punishment regulation of the fraternity suggests that the kinship fraternity was a tool to unite consanguinity in late Joseon. One of the reasons which the kinship fraternity became popular in late Josean resulted from the generalization of a memorial serve with the settlement of Jongbeop order in which they thought much of agnate kinship order. That is, the eldest son was supposed to hold a ceremony for the repose of his ancestors and therefore, people formed the kinship fraternity to hold the ceremony together. Second, they organized the kinship fraternity to prevent themselves from be estranged from relatives, since the split branches of clan increased naturally in late Joseon. Finally, kinship families spread over many different areas and their social movement was activated because of wars, government service, or marriage. The kinship fraternity served as a measure to bind the kinship families together.

암치료에 있어서 체질과 항암효과에 관한 한의학적 연구

성현제,신현규,박갑주,강봉주,은영아,김은해,정세영 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

As one of the chemical and experimental study on cancer treatment in Korea oriental medical hospital. Furthermore, we carried out the cytotoxicity test of extracts of herbal medicine. The results are as follows : About Clinical Aspects of the Oriental Medical Cancer Treatment - (1) Clinical experience is that 420 Oriental medical hospital were surveyed. Number of cancer patient treated by one oriental medical doctor was under 10(about 60%) or from 10 to 20(about 30%). (2) Diagnostic Procedure is that more than 80% of cancer patients were diagnosed by medical doctor of western hospital. (3) Therapeutic Method is that combination of oriental and western medical treatment was used in oriental medical hospital. (4) Relationship between cancer and constitutions is that to the relationship between cancer and constitutions, about 75% responded and most were considered to be Um. About Experimental Study - to evaluate the direct cytotoxicity of hot water and methanol extracts of 34 oriental medical presciptions on stomach cancer cell, SRB assay was carried out. (1) The IC50 value of water extract of Samsoum was 19㎍/㎖ and that of methanol extract was 15㎍/㎖, so that we confirmed Samsoum has a strong direct cytotoxicity. (2) The IC50 values of water extract of Coptidis Rhizoma, methanol extract of Caesalpiniae Lignum and Draba Semen were 10㎍/㎖, 19㎍/㎖ and 12.5㎍/㎖ respectively, so that we confirmed Coptidis Rhizoma, Caesalpiniae Lignum and Draba Semen have a strong direct cytototoxicity. (3) The IC50 value of combinatory prescription of Rhei Rhizoma, Forsythie Fructus and Caesalpiniae Lignum was about 40㎍/㎖.

표면개질 실리카막을 이용한 CO_2 선택투과분리

김성수,최현교,박홍채,김태옥,서봉국 한국환경과학회 2000 한국환경과학회지 Vol.9 No.4

To improve CO_2 permselectivity, a modified silica membrane was prepared by chemical vapor deposition with tetraethoxysilane(TEOS)-ethanol-water, and TEOS-ethanol-water-HCI solution at 300-600℃. The silica was effectively deposited in the mesopores of a γ-alumina film coated on a porous α-alumina tube by evacuating the reactants through the porous wall. In this membrane, CO_2 interacts, to some extent, with the pore wall, and CO_2/N_2 selectivity then exceeds the value of the Knudsen diffusion mechanism, while the membrane derived from TEOS alone has no CO_2 selectivity. The silica membrane prepared from TEOS-ethanol-water-HC1 solution showed that CO_2 permeance was 2.5×10 exp (-7)㏖/s^-1. m^-2. Pa^-1 at 30℃ and CO_2/N_2 selectivity was approximately 3. The CO_2 permeance and selectivity was improved by enlarging the surface diffusion with modification of chemical affinity of the silica pores.

매실박, 당근박, 감귤박 급여가 산란계 난황의 Vitamin E, K 함량에 미치는 영향

최승현,나재천,권오상,박상미,이봉덕,안길환 충남대학교 농업과학연구소 2008 농업과학연구 Vol.35 No.2

This experiment is a quantitative experiment where insoluble Vitamins E and K are extracted from the yolk of the spawning which was fed by by-products of tangerine, carrot, or Japanese apricot. Finally the purpose is to raise contents of the insoluble Vitamins E and K inside the yolk of the spawning. The saponification method through α, α - dipyridyl was used to determine the content of Vitamin E. Diethyl dithiocarbamate assay was used to examine the content of Vitamin K. The contents of Vitamin E in egg yolks of chicken fed by by-products of tangerine, carrot, or Japanese apricot increased 2 - 3 times compared to control egg, while the contents of Vitamin K almost no changed. 본 실험에서는 감귤, 매실, 당근의 껍데기로 감귤박, 매실박, 당근박을 먹여 산란계의 난황에 들어있는 Vitamin E와 K 함량을 높이고자 했다. Vitamin E 추출방법에는 검화방법인 α, α -dipyridyl에 의한 비색정량법을 사용하였으며 전처리 과정 중 석유 ether를 가하여 층을 분리하는 과정과 증류수를 가하여 층을 분리하는 과정에 있어서 신중을 가하였고 신속한 시료 전처리과정이 요구되었다. Vitamin K 추출에는 Diethyl dithiocarbamate에 의한 방법이 사용되었다. 실험결과 일반난황에서의 Vitamin E 함량보다 실험난황에서의 Vitamin E 함량이 2배 이상 높아졌음을 알 수 있었던 반면 Vitamin K의 함량은소량 증가하여 큰 변화가 없었다. 위의 결과를 통해서 난황에 이전된 Vitamin E의 종류가 무엇이며 어떠한 형태의 Vitamin E가 이전이 많이 되었는지를 확인하는 실험이 필요할 것이다. 이러한 추가적인 실험이 이루어졌을 때 상업적으로 이용한 가치가 있는 가를 고려하여야 할 것이다.

地域經濟活性化를 위한 農村市場開發에 관한 硏究 : 忠南 禮山地域市場을 中心으로

尹畯相,李武鉉,申尹撤,洪性贊,朴奉圭 公州大學校 産業開發硏究所 1994 産業開發硏究 Vol.2 No.-

Since the first year economic development plan, imblanced development of national territory during the economic development process has aggravated remarkable disparity between urban and rural areas. For this reason, this study introduced the development of rural market as one of the development strategies of regional economic to correct the imblance and relieve regional disparity. The purpose of this study were to look into the present situation of traditional rural market and to analyze the problems for the rural development in view of the current road situations in the rural areas and status of marketing facilities in market center and to measure the degree of rural area people's satisfaction to the rural market and to suggest the development plan of activating for rural market center. To collect data, the Yesan Gun rural market were selected and a total of 591 residents and 178 merchants were sampled as final subjects of survey. Interview and/or questionnaire method was the main method of data collection. The major findings of this study were as follows: 1) The population of Yesan Gun has decreased 2.85 persons per year from in 1984, but the number of vehicles were increased 2.85 times than in 1989. And the parking capacity of Yesan Eup was only 129 vehicles which were below of the total vehicles of Yesan Gun area (14,352). The number of Yesan area markets were 8 markets which consisted of 1 permanent market and 7 periodic markets. But as the economy has been developed, the conditions of rural markets have been changing. That is, the role of periodic market tends to be weakened with the growth of large cities, reinforcement of permanent markets, development of traffic facilities, large production, preferring high quality goods. 3) Generally, the people of Yesan Gun were attached for purchasing the necessaries of life and comodities and farming materials to ① Yesan Eup ② Seoul ③ Chonan Shi ④ Hongsung gun ⑤ Daejeon Shi. 4) The degree of community people's satisfaction to the town market presented 26.6% which meaned higher than dissatisfaction(9.5%). And the degree of people's inconvenience of accessibility to market center by transferring of bus terminal presented 64.2% which meaned higher than average. 5) The degree of people's dissatisfaction of traffic system in Yesan gun area presented followings: the road networks(61.5%), parking facility(68%), bus route(54%). 6) By the survey of merchants of Yesan gun area, on the average, it showed followings: the size of store was 6-10 pyeong(40%), the type of enterprise was retail dealer(70.9%), and purchasing place was wholesale dealer from Seoul(51.8%). 7) And they thought that Yesan town market were too small(70.8%), and the diversifying of goods was not enough(35.5%). 8) The merchants of Yesan area showed that the degree of into venience to traffic system was 72.7% and its to parking facility was 83.3%. And they complained that community administration agency have not tried to activate market(79.1%). Based on the results of this study, the following recommendation were made for activating regional economy and community market. That is, it is to strengthen the economic function in community market so as to suffice the economic and social activities for settlement area as their living space. And it is necessary to improve the interrelationship of the central functions. 1) So, the accessibility between market center and its surrounding areas must be rised. ① the enforcing preferentially to pave the bus terminal and market center to link two place. ② the running of shuttle-bus two place every regular market day. ③ the widening and connecting the road to rise accessibility between market center and its surrounding area. ④ the enforcement of parking facility around market center. ⑤ the constructing marketing centered area as intergrated body of various marketing facilities in the adjacent site is the centered area planned to achieve efficient marketing. 2) The modernization and specialization market center facilities. 3) The strengthening of drawing surrounding area people into Yesan market center. So, the following recommended: ① the development of special products market ② inducing special projects ③ the development tour and leisure course drawing industrial facilities. 4) And it needs to enforce community people's local patriotism and to support community markets by administration agency.

광섬유 방사선 센서와 EBT 필름을 이용한 심부선량 백분율 측정 및 비교

조동현,장경원,유욱재,신상훈,이봉수,문주현,박병기 제주대학교 방사선응용과학연구소 2008 방사선응용과학연구소논문집 Vol.22 No.-

In this study, fiber-optic sensor is fabricated to measure PDD of CLINAC. As a scintillating light generated by a high energy X-ray from the medical LINAC is measured using photo diode amp system, It is expected that a high-resolution, real-time fiber-optic dosimeter for medical LINAC can be developed.

몇몇 플라보노이드의 항상화활성의 비교 연구

정현균,정민아,송동업,안봉환,양성렬 全南大醫大 2000 전남의대학술지 Vol.36 No.2