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      • KCI등재

        일제 식민지기 ‘원산노동병원’의 설립과 그 의의

        정일영(JEONG, Il yeong),신영전(SHIN, Young-jeon) 대한의사학회 2016 醫史學 Vol.25 No.3

        On July 3, 1928, the Wonsan Labor Union established the Wonsan Laborers’ Hospital in Seoku-dong, Wonsan for the purpose of reducing medical consultation fees for its members. The union’s efforts to improve the welfare of its members include the establishment of an educational institute, a consumers union, a barbershop, and a relief department. The Laborers’ Hospital, which began with ten wards, was led by a team of two doctors, one midwife, two pharmacists, and four nurses. The two doctors were Cheol-sun Cha and Jeong-kwon Lee, and the midwife/nurse was Sun-jeong Kim. Union members received a 40% discount on medicine, and this was utilized by a daily average of 60 to 70 workers, or 21,000 workers annually. The Laborers’ Hospital was clearly distinct from medical facilities founded as charity institutions in that funds were raised by the recipients themselves, and that the recipients formed a community based on their common status as laborers. However, the Wonsan Laborers’ Hospital was shut down in roughly April 1929 due to the breaking of the general strike, and the heightened suppression of union activities prevented any additional opening of laborers’ hospitals until Korea’s liberation from Japan. Nevertheless, the history of the Wonsan Laborers’ Hospital represents a key development in Korea’s health coverage. It is not adequate to declare, as was the case in past research, Korea’s health coverage to be simply an imitation of the Western system and lacking its own history. Despite some differences in scale and operation, the development of health coverage in the Korean peninsula is in line with the history of health coverage development in the West. The Wonsan Laborers’ Hospital, founded and operated by the laborers themselves, thus holds great significance in the history of Korea’s health coverage, The findings of this study are expected to stimulate new and more diverse discussions on the history of health coverage in Korea.

      • 강원지역 중소기업의 환경경영 실태와 과제

        전영승,박은정 한국산학경영학회 2004 산학경영연구 Vol.17 No.1

        본 연구의 목적은 ISO14001 인증 취득 현황조사를 통해 강원지역 중소기업의 환경경영 실태와 과제를 파악하고 환경경영의 활성화를 위한 방안을 모색하는 것이다. 주요 결과를 요약하면 다음과 같다. 첫째, 2003년 4월 현재 우리나라의 ISO14001 인증획득 업체수는 1,215개 업체인데 비해 강원지역 중소기업의 ISO14001 인증획득 업체는 광역지방자치단체 중 최하위 수준인 26개 업체에 불과하였다. 둘째, 인증 미획득 기업들이 인증을 받지 않으려는 이유로 '인증 획득 및 유지에 소요되는 비용이 효익보다 크다'는 점을 제시하였다. 셋째, ISO14001 인증을 획득한 기업이나 ISO14001 인증 미획득 기업이나 인증을 획득한(하려는) 가장 큰 이유는 '기업의 이미지 향상'이었으며, 인증 획득기업이 환경경영시스템 도입 후 얻은 효과도 '기업의 이미지 향상'으로 나타났다. 넷째, ISO14001 인증을 획득한 기업들은 환경경영시스템을 도입할 때 문제점으로 '문서작성 및 비용에 관한 부담'과 '인력 부족'에 관한 응답이 많았다. 위와 같은 연구의 주요 결과를 바탕으로 강원지역 중소기업의 환경경영 활성화를 위한 과제와 방안을 제시하면 다음과 같다. 첫째, ISO14001 인증 미획득 기업 대부분이 ISO14001에 대한 인지도가 낮아 이에 대한 지속적이고 적극적인 홍보와 교육 및 연수제도가 필요하다는 점이다. 둘째, 환경경영 관련 인력이 부족함으로 전문 인력의 양성을 위한 교육프로그램의 실시, 보조금 지급의 확대, 상담부서 및 상담창구의 개설, 관련 정보의 데이터 베이스화나 소프트웨어의 개발이 필요하다. 셋째, 저렴한 비용과 간단한 절차를 통해 인증을 받을 수 있는 중소기업용 공적 인증제도의 신설, 혹은 단체인증제도, 공단 인증제도 등을 적극 고려할 필요가 있다. The purpose of this study is to understand the realities and the subject of environmental management for small and medium-sized companies in Gwangwon area, through surveying the present status as to acquiring the certification of ISO14001, and to seek for a plan to facilitate environmental management. Given summarizing key results, those are as follows. First, while the number of companies in our country which acquired the certification of ISO14001, amounts to 1,215 businesses as of April of 2003, the number of small and medium-sized companies in Gwangwon area which obtained the certification of ISO14001 reached only 26 businesses, the lowest level among metropolitan municipalities. Second, for the reason that companies who didn't acquire the certification, strive not to receive the certification, it did present the point that 'costs to be needed in acquiring and maintaining the certification are larger than practical benefit. Third, the biggest reason for either companies which did not acquire the certification of ISO14001 or companies which did (try to) acquire the certification of IS01400, was 'enhancement of a corporate image,' and the effect after a company who obtained the certification introduced the environmental management system, was also shown to be 'the improvement of a corporate image.' Fourth, many companies who acquired the certification of IS01400 pointed out the response related to 'burden on document creation and costs' and 'lack of manpower' as problems when introducing the environmental management system. On the basis of major results of a study as the above, given presenting the subject and a plan for activating the environmental management of small and medium-sized companies in Gwangwon area, those are as follows. First, because most of companies who did not obtain the certification of IS01400 have low recognition of ISO14001, it needs continuous and positive publicity, education and a training system. Second, it requires to carry out an educational program to nurture professional manpower due to lack of manpower relevant to environmental management, to expand payment of subsidies, to open exclusive-charge department and consulting contact, to have the relevant information be database and to develop software. Third, in order to make the certification obtained through inexpensive costs and simple procedures, it needs to positively consider the creation of public approval system for a small and medium-sized company, group approval system, industrial-complex approval system, and others.

      • SCOPUSKCI등재
      • D-Amino Acid Aminotransferase 활성보유 고온성미생물의 탐색 및 분류학적 특성 연구

        곽미선,이승구,정상철,서승현,이재흥,전영중,김영호,성문희 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

        To acquire an industrially useful biocatalyst for the enzymatic synthesis and production of various D-amino acids, 1,300 thermophiles isolated from the soil of Korea were analyzed for D-amino acid aminotransferase (D-AAT) activity. The enzyme activity was found from 110 strains of isolated thermophiles revealing its wide occurrence in thermophiles. Enzyme activity and thermal stability of the D-AAT producers were compared. Finally we have selected four thermophiles as producers of potent biocatalysts for the D-amino acid production; two therrnophiles, Bacillus sp. LK-I and LK-2, having higher specific activity and two thermophiles, B. stearothermophilus KL-01 and Bacillus sp. KLS-0l, having higher thermal stability than the D-AAT producers. Taxonomic and physiological characteristics of the four isolated thermophiles were described herein.

      • SCOPUSKCI등재

        L-라이신 발효에 있어서 당밀전처리의 영향

        신현철,김성준,성진석,전영중,이재흥 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.3

        Can molasses, the most widely used carbon source for the industrial fermentation of L-lysine, usually contains a high concentration of calcium ions which tend to cause scaling problem in the recovery process. To remove the calcium ions, cane molasses was pretreated with sulfuric acid by adjusting the pH to 2.5~3.5. When the pretreated solution was directly heat-sterilized and used in the fermentation, a significant reduction in L-lysine production was observed. In this paper, we proved that sucrose is a superior substrate for L-lysine fermentation of that of glucose or fructose and that the above-mentioned decrease of L-lysine production was caused by the hydrolysis of sucrose in the molasses when the molasses was heat-sterilized at a low pH. The problem was overcome by adjusting the pH of molasses to neutral before sterilization.

      • 김치 관련 연구문헌의 분류분석 및 김치연구의 동향 (Ⅲ)

        최홍식,김재이,민병태,전정태,공연희,홍정진,김나영 부산대학교 김치연구소 2002 김치의 과학과 기술 Vol.8 No.-

        About 200 research papers and patents on kimchi(Korean fermented vegetable food) published In the years of 1997-2001 were collected and analyzed for the classification and review. This article covers the classified topics on the natures and kinds of raw materials, fermentation and related microorganisms, processing / preservation, kimchi packaging, biochemical changes, enzymes, quality, food chemistry, functional klmchi, general consideration on kimchi, and also some research nerds In the future.

      • n-CdS_(0.46)Se_(0.54)/p-Cu_92-x)S_(0.46)Se_(0.54) 이종접합 태양전지의 제작과 그 특성에 관한 연구

        유상하,최승평,이상열,홍광준,서상석,김혜숙,전승룡,윤은희,문종대,신영진,정태수,신현길,김택성,유기수 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-

        승화방법에 의해 CdS_0.46Se_0.54 단결정을 성장하여 결정구조를 조사하고, Van der Pauw 방법으로 Hall effect를 측정하여 carrier density의 온도 의존성과 mobility의 온도 의존성을 조사하였다. 성장된 CdS_0.46Se_0.54 단결정을 치환반응하여 n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 이종접합 태양전지를 제작하였다. Spectral response, 전류-전압특성 및 전력변환 효율을 조사하여 그 결과로부터 개방전압은 0.48V, 단락 전류 밀도는 21mA/㎠, fill factor와 전력변환효율은 각각 0.75와 9.5%를 얻었다. CdS_0.46Se_0.54 single crystal was grown by a sublimation method. The crystal structure and the temperature dependence of carrier density and mobility of CdS_0.46Se_0.54 single crystal were studied. Heterojunction solar cells on n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 were fabricated by the substitution reaction. The spectral response, the J-U characteristics and the conversion efficiency of the n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells were studied. The open-cricuit voltage, short-circuit density, fill factor and conversion efficiency of n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells under 80mW/㎠ illumination were found to be 0.48V, 21mA/㎠, 0.75 and 9.5%, respectively.

      • KCI등재
      • KCI등재

        Differential Cytotoxicity of Penta-O-galloyl-β-D-glucose in Human Cancer and Normal Cell Lines of Various Origins

        Hyeon-Jeong Lee(이현정),Min-Gyeong Kim(김민경),Song-Yeong Lee(이송영),Min-Hyock Song(송민혁),Yoon-Dong Kim(김윤동),Jeong-Sook Ha(하정숙),Gie-Joon Jeong(정계준),Gyu-Jin Rho(노규진),Byeong-Gyun Jeon(전병균) 한국생명과학회 2016 생명과학회지 Vol.26 No.11

        본 연구는 다당체의 한 종류인 penta-O-galloyl-β-D-glucose (PGG)가 사람의 여러 조직에서 기원하는 여러 암세포주(A-549, MDA-MB-231, U87-MG, MCF-7 및 PANC-1), 정상 MRC-5 태아 섬유아세포 그리고 사랑니에서 유래한 간엽줄기세포(DPSCs)에 미치는 세포독성 효과를 조사하였다. IC50값은 다른 세포주에 비해 높은 증식률을 나타내는 A-549 및 MDA-MB-231 암세포주에서 유의적으로 낮게 관찰되었다. 10 uM의 PGG가 포함된 배양액에서 세포를 7일 동안 배양한 결과, 세포배가시간은 모든 세포주에서 유의적으로 늘어났고, 세포배가시간과 IC50값의 관계를 조사한 결과, 세포배가시간이 늘어남에 따라 IC50값은 비례적으로 증가됨을 증명하였다. 또한, 10 uM의 PGG로 처리된 세포주들은 노화와 관련된 ß-galactosidase의 활성도가 높게 관찰되었다. 특히, telomerase 활성도는 A-549 및 MDA-MB-231 암세포주에서 다른 세포주에 비하여 현저히 감소하는 것을 관찰하였다. 이러한 결과를 바탕으로 PGG는 높은 증식률을 보이는 암세포주에서 높은 세포독성효과를 나타내어 잠재적인 항암물질임을 증명하였다. The present study examined the cytotoxic effects of 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose (PGG), known as the pentahydroxy gallic acid ester of glucose, in the various human cancer cell lines (A-549, MDA-MB-231, U87-MG, MCF-7 and PANC-1), normal MRC-5 fetal fibroblasts, and dental papilla tissue-derived mesenchymal stem cells (DPSCs). Significantly (p<0.05) lower half maximal inhibitory concentration (IC50) values were observed in the A-549 and MDA-MB-231 cells showing a high proliferation capacity, compared with other cancer and normal cell lines with a relatively low proliferation capacity. The population doubling time (PDT) was significantly (p<0.05) higher in the 10 μM PGGtreated cell lines than those of untreated control cell lines. The present study demonstrated that the IC50 value increases proportionally to the extending PDT. A high cell number with senescence-associated ß-galactosidase activity was also observed in the 10 μM PGG-treated cells compared with those of untreated control cells. Moreover, the level of telomerase activity was significantly (p<0.05) decreased with 10 μM PGG treatment, especially in A-549 and MDA-MB-231 cells showing a high proliferation capacity. Based on these observations, PGG could serve as a potent agent for cancer chemotherapy, as its treatment was more effective in cells with a high proliferation capacity.

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