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함수연 대한영상의학회 1989 대한영상의학회지 Vol.25 No.5
A case of Fascioliasis of common bile duct is confirmed by visualization of adult fluke. Fascioliasis caused by Fasciola hepatica is common parasitic disease in cattle and sheep. Human is an accidental host. ERCP demonstrated irregular linear conglomerated filling defects in common bile duct . Through surgical intervention we found adult flukes of F. hepatica and adenomatous hyper-plasia of common bile duct.
췌장암의 방사선학적 진단: 전산화단층촬영(CT)과 초음파검사(US)를 중심으로
함수연 대한영상의학회 1991 대한영상의학회지 Vol.27 No.5
Fifty nine CT scans, 54 ultrasonograms(US), 21 endoscopic retrograde cholangiopancreatographies(ERCP) and 11 angiograms, of 59 pancreatic malignancies were retrospectively reviewed to assess the diagnostic value of imaging modalities, especially that of the CT and US. Sixty three percent of the cases showed a lesion less than 5cm in diameter, more than 60% of the cases were located in the head portion, and most of the hand lesions were smaller than 5cm in diameter. The CT density of the tumor showed 24 with mixed density, 22 with hypodensity, 10 with isodensity and one with hyperdensity. Echopatterns of the tumor were hypoechoic or cystic in 35, mixed echoic in 7, isoechoic in 3, and hyperechoic in 3 cases. In comparing CT with US, the detectability of the pancreas mass was the same in the two modalities, and with regard to other a spects, the CT was slightly superior than the US, but not statistically significant.
방사성동위원소 표지 단일클론항 GGT 항체를 이용한 간 질환에 대한 연구
함수연,최재걸,이민재,정규병,김명곤,류총근 고려대학교 의과대학 1995 고려대 의대 잡지 Vol.32 No.3
This study was designed to investigate whether radioisotope labeled tissue-specific monoclonal anti-γ Glutamyltransferase (GGT) antibodies can be used for the scintigraphic localization of abnormal hepatic tissue of rat. Three monoclonal anti-GGT antibodies (GGT MAb-1, 5, 6) were biochemically purified from the ascites of BALB/c mice which were injected hybridomas secreting monoclonal antibody to a 7.17 mg of immunoglobulin per ml of protein and the mean immunoglobulin amount was 4.98 mg. Then I-131 was incorporated to GGT MAbs by lodogen method with an average labeling efficiency of 77.4% (GGT MAb), and 86.8% (GGT PAb) and in case of Tc-99m by sodium dodesylsulfate, they were 57.7% (GGT MAb), and 77.6% (GGT PAb) respectively. In vitro assay revealed that there was a significant correlation between the result of immunohistochemistry and that of tissue autoradiography according to the type of tissue and monoclonal antibodies in normal heaptic tissue, preneoplastic liver and normal kidney. Modified GGT MAb-1 was specific for the hepatic tissue of preneoplastic liver, GGT MAb-5 for the normal liver, and GGT MAb-6 for the normal kidney. In vivo assay revealed selective localization of radioactivity over tissue specific GGT distributed organs of Wister rat by immunoscintigraphy and tissue γ-counting. In conclusion, radioisotope labeled anti-GGT antibodies might be used for both in vitro and in vivo assays and could be used for the localization of musine hepatic disorders by immunoscintigraphy.
기업 내 온라인 커뮤니케이션 채널의 만족도가 커뮤니케이션 효과에 미치는 영향 요인 분석
함수연,김종우 한국IT서비스학회 2018 한국IT서비스학회지 Vol.17 No.4
Effective internal communication is known to have a positive impact on business performance, but there is a lack of research on the effects of online channels for workplace communication. This study using regression analysis examines how task-technology fit, information richness, self-efficacy, perceived ease of use, and perceived usefulness related to online communication channels affect not only the satisfaction with the tools but also the effectiveness of them. Additionally, we verify how the organizational culture of online and offline communication shows the control effect. As a result, all five variables were positively correlated with internal communication channels satisfaction, and we found that the organizational culture of online and offline communication controls the relationship between online communication channels satisfaction and effectiveness.
청소년 자해에 대한 정신분석학적 이해: 멜라니 클라인의 두자리 개념과 윌프레드 비온의 O개념을 중심으로
함수연 ( Hahm¸ Su Yeon ) 한국정신분석심리상담학회 2021 정신분석심리상담(구 정신역동치료) Vol.5 No.-
본 연구의 목적은 청소년의 자해가 갖는 의미를 살펴보고 이를 통해 상담학적 이해를 시도하고자 함에 있다. 특히 청소년 자해에 대한 현황과 기존의 선행연구들을 통해 자해에 대한 연구의 필요성에 대해 살펴볼 것이다. 또한 청소년 자해에 대해 대상관계학파인 멜라니 클라인과 윌프레드 비온의 이론을 통해 알아볼 수 있다. 먼저 클라인의 두 자리 개념인 편집-분열적 자리와 우울적 자리의 각 개념들의 특징을 통해 자해행동에 대해 살펴볼 것이다. 특히 편집-분열적 자리의 개념인 공격성과 우울적 자리의 개념인 죄책감을 바탕으로 이해해보고자 한다. 각 자리에서의 자해행동을 살펴보는 것을 통해 자해행동의 여러 의미를 탐색해 볼 수 있다. 이어 비온의 O개념을 중심으로 자해행동을 살펴볼 것이며, 고통을 견뎌내는 능력으로 알파-기능을 이해해보고자 한다. 특히 알파-기능의 부재가 어떻게 청소년의 자해행동으로 연결될 수 있는지 살펴보고자 한다. 또한 청소년의 자해를 비온이 설명한 -K에서의 행동으로 이해해보고, 이에 대한 치유의 시간과 공간에 대해 살펴볼 것이다. 먼저 그롯슈타인이 설명한 다차원의 O시간 개념에서 찾아낼 수 있는 경험의 상관관계를 통해 왜곡되고 혼란스러운 시간을 경험하는 -K를 담을 수 있는 시간으로 이해해볼 것이다. 그리고 더 나아가 치유의 공간이자 무한의 공간인 O공간 개념을 살펴볼 것이다. 이때 O공간은 레브리 상태를 바탕으로 한 상호관계를 중심으로 형성될 수 있음을 살펴보고자 한다. The purpose of this study is to examine the meaning of self-injury in adolescents and to try to understand it in Psychoanalysis. In addition, the current status of self-injury in young adults as well as the necessity of research on self-injury are explored through previous studies. Self-injury in adolescents can be explored with the theories of object relations theorists Melanie Klein and Wilfred Bion. First, self-injury behaviors will be investigated based on the characteristics of each concept of the two position concepts of Klein: the paranoid-schizoid position and the depressive position. In particular, the understanding will be based on the concept of the paranoid-schizoid position, aggression, and that of the depressive position, guilt. Different meanings of self-injury behaviors can be examined by looking at the self-injury behaviors in each position. Next, this study explores self-injury behaviors based on Bion’s concept of “O” and investigates the alpha-function, the capacity to tolerate frustration. In particular, it aims to examine how the absence of alpha-function can lead to self-injury behaviors in adolescents. This study tries to understand self-injury in adolescents based on Bion’s behavior in -K and examines the time and space for healing. First, it will be understood as a time that can contain -K where distorted and chaotic time is experienced through the correlation of experiences found in the multidimensional O-time concept explained by Grotstein. Furthermore, the concept of space O, a space of healing and an infinite space, will be explored. At this time, it will be explored that space O can be formed centering on interrelation based on the state of reverie.