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Park, Se Jin,Jeon, Hyo Sang,Cho, Jin Woo,Hwang, Yun Jeong,Park, Kyung Su,Shim, Hyeong Seop,Song, Jae Kyu,Cho, Yunae,Kim, Dong-Wook,Kim, Jihyun,Min, Byoung Koun American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.49
<P>Significant enhancement of solution-processed CuInxGa1-x(Se,S)(2) (CIGSSe) thin-film solar cell performance was achieved by inducing a band gap gradient in the film thickness, which was triggered by the chalcogenization process. Specifically, after the preparation of an amorphous mixed oxide film of Cu, In, and Ga by a simple paste coating method chalcogenization under Se vapor, along with the flow of dilute H2S gas, resulted in the formation of CIGSSe films with graded composition distribution: S-rich top, In- and Se-rich middle, and Ga- and S-rich bottom. This uneven compositional distribution was confirmed to lead to a band gap gradient in the film, which may also be responsible for enhancement in the open circuit voltage and reduction in photocurrent loss, thus increasing the overall efficiency. The highest power conversion efficiency of 11.7% was achieved with J(sc) of 28.3 mA/cm(2), V-oc of 601 mV, and FF of 68.6%.</P>
김세권,최진삼,이창국,변희국,전유진,이응호,박인용 대전산업대학교 반도체기술연구소 1999 半導體技術硏究所報 Vol.1 No.-
참치 뼈에서 추출한 hydroxyapatite를 출발물질로 여러 가지 세라믹 복합체를 제조하여 인공체액에서의 hydroxyapatite 복합체간의 화학결합을 조사하였다. hydroxyapatite 복합체들은 인공체액에서 4주 후부터 화학 결합성질을 나타내었다. 결합강도는 bioglass가 가장 강하게 나타났으며, 조성에 따른 의존성은 관찰할 수 없었다. 인공체액에서 복합체들은 이들의 경계면에서 불균일 핵생성 및 성장에 의해 화학적 결합으로 이루어졌다. Chemical bonding was investigated in the simulated body fluid of several selected hydroxyapatite-containing composites. The hydroxyapatite-containing composites chemically bonded with each other in the simulated body fluid after 4 weeks. Bioglass was strongly bonded in the simulated body fluid, but bonding strength was not depended on composition. Their composite bodies were chemically bonded by heterogeneous nucleation and growth at the interfaces of the specimens in the simulated body fluid.
光波長이 오이(Cucumis sativus L.) 플러그苗의 生長에 미치는 影響
용영록,전지영,황세진,김일섭,정천순 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1
This research was carried to find out the optimum artificial light condition for plug seedling production of high quality cucumber through investigating growth response of the seedling by both light wave length and treatment period. The treatment with blue and red fluorescent lamp increased the fresh weight involving hypocotyl and root and controlled the elongation of hypocotyl, compared with other treatments. The 30-day-old seedling treatment with blue and red light for 12 hours showed that vegetative growth including root, stem and leaves was better than that of seedling treated with other lamps. Seedling under blue and red light for 12 hours grew 60.0mm and 0.55g in length and weight of hypocotyl. respectively, Hypocotyl length and weight were 44.9mm and 0.62g when seedling was grown under above light condition for 6 hours. Total chlorophyll contents of hypocotyl were highest in the light mixing treatment, and this accelerated greening. Morphological characteristics by investigating cross and longitudinal section of 30-day-old cucumber seedling treated with the mixing fluorescent lamps indicated that epidrmis tissues were usually single layer and thicker, resulting in small, compact and non-intercellular spaces of cells. On the other hand, epidermis tissues of the control composed of large, longer and round cells and cortex tissues showed large intercellular spaces between cells. Longitudinal section of photo-treated hypocotyl showed that there were more shorter cells and non-intercellular spaces of cells than untreated tissues. As a result, blue and red light mixing treatment controled the cell elongation of seedling hypocotyl, resulting in shortening hypocotyl of cucumber seedling.
이강석,전헌수,이아름,정세교,배선민,조동완,옥진은,김경화,양민,이삼녕,안형수,배종성,하홍주,Lee, Gang-Seok,Jeon, Hun-Soo,Lee, Ah-Reum,Jung, Se-Gyo,Bae, Seon-Min,Jo, Dong-Wan,Ok, Jin-Eun,Kim, Kyung-Hwa,Yang, Min,Yi, Sam-Nyeong,Ahn, Hyung-Soo 한국결정성장학회 2010 한국결정성장학회지 Vol.20 No.3
높은 광흡수 계수를$(1{\times}10^5cm^{-1})$ 가지는 CIGS는 Ga의 비율에 따라서 밴드갭을 조절할 수 있다는 장점을 지니고 있다. CIGS의 밴드갭은 Ga의 비율에 따라 $CuInSe_2$(Eg: 1.0 eV)에서 $CuGaSe_2$(Eg: 1.68 eV)까지의 범위에 존재하며, 태양전지에 서 이상적인 fill factor 모양을 가지도록 Ga의 비율을 높게 조성한다. CIGS 흡수층을 제작하는 방법에는 co-evaporator 방식이 가장 널리 사용되며 연구되고 있다. 이에 본 연구에서는 수평 형태의 hydride vapor transport (HVT)법을 고안하여 CIGS 나노 구조 및 에피성장을 시도하였다. HVT법은 $N_2$ 분위기에서 원료부의 CIGS 혼합물을 HCl과 반응시켜 염화물 기체상태로 변환 후 growth zone까지 이동하여 성장을 하는 방식이다. 성장기판은 c-$Al_2O_3$ 기판과 u-GaN을 사용하였다. 성장 후 field emission scanning electron microscopy(FE-SEM)과 energy dispersive spectrometer(EDS)를 이용하여 관찰하였다. The Cu$(In_{1-x}Ga_x)Se_2$ is the absorber material for thin film solar cell with high absorption coefficient of $1{\times}10^5cm^{-1}$. In the case of CIGS, the movable energy band gap from $CuInSe_2$ (1.00 eV) to $CuGaSe_2$ (1.68 eV) can be acquired while controlling Ga contain ratio. Generally, the co-evaporator method have used for development and fabrication of the CIGS absorption layer. However, this method should need many steps and lengthy deposition time with high temperature. For these reasons, in this paper, a new growth method of CIGS layer was attempted to hydride vapor transport (HVT) method. The CIGS mixed-source material reacted for HCl gas in the source zone was deposited on the substrate after transporting to growth zone. c-plane $Al_2O_3$ and undoped GaN were used as substrates for growth. The characteristics of grown samples were measured from SEM and EDS.
Biflorin Ameliorates Memory Impairments Induced by Cholinergic Blockade in Mice
( Se Jin Jeon ),( Boseong Kim ),( Byeol Ryu ),( Eunji Kim ),( Sunhee Lee ),( Dae Sik Jang ),( Jong Hoon Ryu ) 한국응용약물학회 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.3
To examine the effect of biflorin, a component of Syzygium aromaticum, on memory deficit, we introduced a scopolamine-induced cognitive deficit mouse model. A single administration of biflorin increased latency time in the passive avoidance task, ameliorated alternation behavior in the Y-maze, and increased exploration time in the Morris water maze task, indicating the improvement of cognitive behaviors against cholinergic dysfunction. The biflorin-induced reverse of latency in the scopolamine-treated group was attenuated by MK-801, an NMDA receptor antagonist. Biflorin also enhanced cognitive function in a naive mouse model. To understand the mechanism of biflorin for memory amelioration, we performed Western blot. Biflorin increased the activation of protein kinase C-ζ and its downstream signaling molecules in the hippocampus. These results suggest that biflorin ameliorates drug-induced memory impairment by modulation of protein kinase C-ζ signaling in mice, implying that biflorin could function as a possible therapeutic agent for the treatment of cognitive problems.
Positive feedback regulation of Akt‐FMRP pathway protects neurons from cell death
Jeon, Se Jin,Han, Seol‐,Heui,Yang, Sung‐,Il,Choi, Ji woong,Kwon, Kyoung Ja,Park, Seung Hwa,Kim, Hahn Young,Cheong, Jae Hoon,Ryu, Jong Hoon,Ko, Kwang Ho,Wells, David G,Shin, Chan Young Blackwell Publishing Ltd 2012 Journal of Neurochemistry Vol.123 No.2
<P><I>J. Neurochem.</I> (2012) <B>123</B>, 226–238.</P><P><B>Abstract</B></P><P>Fragile X syndrome (FXS), the most common single genetic cause of mental retardation and autistic spectrum disease, occurs when <I>FMR1</I> gene is mutated. <I>FMR1</I> encodes fragile X mental retardation protein (FMRP) which regulates translation of mRNAs playing important roles in the development of neurons as well as formation and maintenance of synapses. To examine whether FMRP regulates cell viability, we induced apoptosis in rat primary cortical neurons with glutamate <I>in vitro</I> and with middle cerebral artery occlusion (MCAO) in striatal neurons <I>in vivo</I>. Both conditions elicited a rapid, but transient FMRP expression in neurons. This up‐regulated FMRP expression was abolished by pre‐treatment with PI3K and Protein Kinase B (Akt) inhibitors: LY294002, Akt inhibitor IV, and VIII. Reduced FMRP expression <I>in vitro</I> or <I>in vivo</I> using small hairpin <I>Fmr1</I> virus exacerbated cell death by glutamate or MCAO, presumably <I>via</I> hypophosphorylation of Akt and reduced expression of B‐cell lymphoma‐extra large (Bcl‐xL). However, over‐expression of FMRP using enhanced green fluorescent protein (eGFP)‐FMRP constructs alleviated cell death, increased Akt activity, and enhanced Bcl‐xL production. The pro‐survival role of Akt‐dependent up‐regulation of FMRP in glutamate‐stimulated cultured neuron as well as in ischemic brain may have a clinical importance in FXS as well as in neurodegenerative disorders and traumatic brain injury.</P>
Jeon, Se Jin,Ryu, Jong Hoon,Bahn, Geon Ho The Korean Society of Applied Pharmacology 2017 Biomolecules & Therapeutics(구 응용약물학회지) Vol.25 No.3
Myelin is a specialized structure of the nervous system that both enhances electrical conductance and insulates neurons from external risk factors. In the central nervous system, polarized oligodendrocytes form myelin by wrapping processes in a spiral pattern around neuronal axons through myelin-related gene regulation. Since these events occur at a distance from the cell body, post-transcriptional control of gene expression has strategic advantage to fine-tune the overall regulation of protein contents in situ. Therefore, many research interests have been focused to identify RNA binding proteins and their regulatory mechanism in myelinating compartments. Fragile X mental retardation protein (FMRP) is one such RNA binding protein, regulating its target expression by translational control. Although the majority of works on FMRP have been performed in neurons, it is also found in the developing or mature glial cells including oligodendrocytes, where its function is not well understood. Here, we will review evidences suggesting abnormal translational regulation of myelin proteins with accompanying white matter problem and neurological deficits in fragile X syndrome, which can have wider mechanistic and pathological implication in many other neurological and psychiatric disorders.