HPV에 감염된 자궁경부 상피세포의 Keratin 아형 변화에 관한 연구

기근홍,이영미,장원재,임용,임성철,김창원,전호종 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

The human papillomavirus (HPV) are wide spread in the world, causing proliferation of epidermal and mucosal surface. Certain papillomaviral types are oncogenic in vivo and in vitro. HPV DNA has been detected in most of cervical lesions such as condyloma acuminata, dysplasias, and invasive carcinomas. The materials for this study consisted of 5 dysplasias. 5 squamous cell carcinomas, and 5 exocervix for control, that resected for definite treatment of uterine disease at Chosen University Hospital from January, 1991 to December, 1993. All cases were performed of in situ hybridization for HPV DNA type 6/11, 16, and 18. And also immununohistochemical stain for panel of monoclonal cytokeratin (CK) antibodies were done. The result obtained is as fallows : 1. HPV DNA type 6/11 are detected in all dysplasias. HPV DNA type 16 and 18 are detected in squamous cell carcinomas. 2. Stratifed squamous epithelium of exocervix are positive staining for CK 1, CK 5/6, CK 8, CK 13, CK 14, and CK 19. HPV DNA type 6/11 infected cells are positive for CK 1, CK 13, CK 14, CK 17, CK 18, and CK 19. HPV DNA type 16/18 infected cells are positive for CK 1, CK 5/6, CK 10, CK 13, CK 14, CK 17, CK 18, and CK 19. In conclusion, HPV infection of uterine cervix is associated with change of normal cytokeratin expression pattern. Dysplastic cells are changed of CK 5/6, CK 8, CK 17 and CK18. Squamous cell carcinoma cells are changed of CK 8, CK 17, and CK 18.

사상 : 농암 김창협의 학문 수용과 지각론

김영훈 ( Young Hoon Kim ),전선숙 ( Sun Suk Jeon ),신창호 ( Chang Ho Shin ) 영산대학교 동양문화연구원 2012 동양문화연구 Vol.11 No.-

본 연구는 조선시대 유학자인 농암(農巖) 김창협(金昌協, 1651-1708)의 학문 수용 과정을 지각론을 중심으로 살펴본 것이다. 김창협은 율곡학파 계열의 학자이지만 퇴계 이황의 학설에 호감을 갖고 이를 긍정하여 자신의 학파와 절충하는 독특한 사상을 전개하였다. 율곡 이이의 사단칠정론에 대해 반대한 것은 아니지만 비판적 입장을 취하면서, 리발(理發)을 중심으로 하는 퇴계 이황의 이론을 수용하였다. 그것은 호락논쟁으로 이어지면서 김창협의 학문적 성숙을 유도하였고, 마침내 지각설이라는 이론 체계로 드러났다. 그의 지각론은 첫째, 성(性)은 성즉리(性卽理)의 입장에서 파악해야 하고 지(智) 또는 리(理)를 중심으로 해석해야 한다는 것, 둘째, 지(智)는 분별의 리(理)로 해석하는 것이 옳고, ‘밝게 비춘다’라는 구절의 해석에서 기미와 색상은 자연스럽게 드러난다는 점, 셋째, 지(智)는 사물의 시비득실(是非得失)의 차별을 구별하고 판단하는 기준이 된다는 점 등이 강조되었다. 다시 말하면, 인간은 사물을 접하게 마련이고, 심(心)의 지각은 이를 감각 기관을 통하여 받으며, 지각을 통해 받아들인 것은 인의예지신(仁義禮智信)의 성(性)에 의해 정해지고, 인간은 자신의 행동을 결정하며, 지는 인간의 내부에서 구체적인 정(情)의 작용인 측은지심, 수오지심, 사양지심, 시비지심의 모습으로 나타난다는 것이다. 이러한 인식은 인간을 주체이고 능동적 역할을 하는 존재로 부각시키는 사상적 근거가 된다. This research aimed to review the process regarding acceptance of studies about Nongam Kim Chang-Hyeop who was a confucian of Joseon Dynasty with the theory of intelligence and perception as the central figure. Being the scholar of Yulgok school, Kim Chang-Hyeop was interested in Toegye Lee Hwang`s theory, agreed with it, made a compromise with his school, and developed his unique thought. Although he did not object to Yulgok Lee Yi`s Sa Dan Chil Jeong Non(四端七情論, it is a theory regarding Sa Dan which are perfect virtue, righteousness, courtesy, and perception according to the theory of Mencius. and Chil Jeong which are pleasure, anger, sadness, joy, love, hate, and avariciousness), he took a critical attitude regarding it and accepted Lee Hwang`s theory with Li Bal(理發, appearing principle law) as the central figure. It was followed by Ho Rak Non Jaeng(湖洛論爭, it is an argument regarding whether human nature and thing`s nature are same or not), led the maturity of Kim Chang-Hyeop`s study, and finally appeared with the theoretical system of intelligence and perception. His theory of intelligence and perception emphasized that first, nature is perceived by "nature is principle law" and interpreted by intelligence or principle law. Second, it is right that intelligence is interpreted by principle law of discernment and smell, taste, and color naturally appear with interpretation of "shine brightly on." Third, intelligence is the criterion of discernment and judgement regarding differentiation of Si Bi Deuk Sil(是非得失, right, wrong, obtaining, and losing) about things. In other words, a person always faces any things, intelligence and perception of mind is arranged through sense organ, things accepted through intelligence and perception are determined by the nature of In Ui Ye Ji Sin(仁義禮智信, perfect virtue, righteousness, courtesy, intelligence, and trust), people determine their action, intelligence appears with the working of feeling which are Cheuk Eun Ji Sim, So O Ji Sim, Sa Yang Ji Sim, and Si Bi Si Sim. This perception becomes a foundation of thought which emphasizes human beings as a active role and a subject.

Changes of Sugar Composition and Related Enzyme Activities during Fruit Development of Asian Pear Cultivars ‘Niitaka’ and ‘Whangkeumbae’

Jin-Ho Choi,Jang-Jeon Choi,Chang-Seok Bang,Jung-Sup Lee,Dong-Woog Choi,Hye-Sun Cho,Jun Cheul Ahn 한국원예학회 2009 Horticulture, Environment, and Biotechnology Vol.50 No.6

We report on the seasonal changes of soluble sugar accumulation and several enzyme activities related to sugar metabolism, in two Asian pear cultivars (Pyrus pyrifolia) cultivars ‘Niitaka’ and ‘Whangkeumbae’. Soluble sugar content increased as the fruit developed and its total contents in matured fruits were 104.6 and 95.1 ㎎ㆍg?¹ fresh weight for ‘Niitaka’ and ‘Whangkeumbae’, respectively. However, the fructose-glucose-sucrose-sorbitol ratio was not significantly changed. Sorbitol-6-phosphate dehydrogenase activity was maintained at high level in leaves and low in fruits throughout the fruit development, although the enzyme activity highly fluctuated in young and mature fruits. NAD-dependent sorbitol dehydrogenase activity increased sigmoidally in both leaves and fruits during fruit development, and correlated with accumulation of total sugar in fruits. Sucrose synthase and sucrose phosphate synthase (SPS) activities remained low in leaves, but higher with two peak fluctuations in fruits. The change of soluble sugar contents positively correlated with SPS activity, based on the seasonal fluctuation of SPS activity and soluble sugar accumulation.

中美个人所得税比较研究

全昶逸(Jeon Chang-il),孫聖鎬(Sohn Sung-ho) 한국국제회계학회 2016 국제회계연구 Vol.0 No.66

Comparison and research on China"s personal income tax systems can have a practical meaning to the direction of personal income tax reforms in China. As China"s economy develops, personal income tax reforms become one of the most interesting tax reforms in China. Because income distribution function of personal income tax is one of the main features of personal income tax systems, it can be enough to exert its function when the differences in income distribution expands, and it can effectively promote an equitable society and actively enhance a harmonious society. China and the United States are the largest countries around the world in terms of major economies, the economic exchanges between the two countries occur much more frequently. Tax collection, tax investigation and methods of the investigation are rigorous and advanced in the U.S. The personal income tax systems in the U.S. are already on the level of mature as the world’s top class, so many countries see it as a guide. This study analyzes the main differences between China and the U.S. of personal income tax systems and identifies the shortcomings of China"s personal income tax systems. Through this analysis, I suggest the adoption of tax indexation, the adjustment of pre-tax deductions in accordance with family circumstances and the implementation of aggregate taxation systems. Meanwhile, the individuals and corporations of the U.S., South Korea, and other countries that do not adopt classification tax systems, should understand the uniqueness of China"s current personal income tax systems before the tax systems are not reformed in China. In addition, depending on the labor contract, the income of the taxpayer is divided into salary income and labor remuneration income, two types of income tax rate are different, and tax payment also can be changed.

난치성 만성정신분열증 환자의 생활의 질에 미치는 정신사회치료 프로그램의 효과에 대한 예비연구

송동호,배민진,이종호,이홍식,김선경,서호석,김찬형,전지용 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : Recent studies of psychosocial adjustment after hospitalization have found that the combination of maintenance antipsychotic drug treatment and psychosocial treatment including psychoeducational program are highly predictive of social rehabilitation and reduction of subsequent relapse. Two groups of patients with refractory chronic schizophrenia were preliminarily compared to determine the effect of a psychosocial treatment program on the quality of life in refractory chronic schizophrenics in an open comparative trial. Methods : One group(N=11) was assigned to approximately six months of the psychosocial treatment program(including psychoeducation program and activity program such as interpersonal relationship program, social skill training, self management program, outings, etc), in a group format, twice a week and a fixed maintenance dosage of clozapine ; while scale(QLS) was used to provide an objective measure of changes in patient's psychosocial functioning and a general assessment of psychopathology was made using the Brief Psychiatric Rating Scale(BPRS). Results : Both BPRS total positive score and the QLS total score, especially in the intrapsychic foundation factor of the scale showed a statistically significant improvement in the psychosocial treatment group. But there was no significant change in both BPRS and QLS scores over a 6-month period in the non-psychosocial treatment group. A significant negative correlation was found between the negative symptom and changes of QLS total, instrumental role and common object and activities scores respectively after receiving a 6-month of the psychosocial treatment program. Conclusion : These results suggest that a psychosocial treatment program including the integration of psychoeducation and a skill training oriented activity program serve as an outpatient treatment modality to improve the quality of the life in refractory chronic schizophrenia. To further clarify the effect of psychosocial treatment in chronic schizophrenia, a randomized trial should be done.

Effect of epidural corticosteroid injection on magnetic resonance imaging findings

( Min Soo Kim ),( Tae Yoon Jeong ),( Yu Seon Cheong ),( Young Wook Jeon ),( So Young Lim ),( Seong Sik Kang ),( In Nam Kim ),( Tsong Bin Chang ),( Hyun Ho Seong ),( Byeong Mun Hwang ) 대한통증학회 2017 The Korean Journal of Pain Vol.30 No.4

Background: Magnetic resonance imaging (MRI) of the spine is the preferred diagnostic tool for pathologic conditions affecting the spine. However, in patients receiving epidural corticosteroid injection (ESI) for treatment of spinal diseases, there is a possibility of misreading of MR images because of air or fluid in the epidural space after the injection. Therefore, we defined the characteristics of abnormal changes in MRI findings following an ESI in patients with low back pain. Methods: We reviewed the medical records of 133 patients who underwent MRI of the lumbar spine within 7 days after ESI between 2006 and 2015.All patients were administered an ESI using a 22-gauge Tuohy needle at the lumbar spine through the interlaminar approach. The epidural space was identified by the loss of resistance technique with air. Results: The incidences of abnormal changes in MRI findings because of ESI were 54%, 31%, and 25% in patients who underwent MRI at approximately 24 h, and 2 and 3 days after ESI, respectively. Abnormal MRI findings included epidural air or fluid, needle tracks, and soft tissue changes. Epidural air, the most frequent abnormal finding (82%), was observed in 41% of patients who underwent MRI within 3 days after injection. Abnormal findings due to an ESI were not observed in MR images acquired 4 days after ESI or later. Conclusions: Pain physicians should consider the possibility of abnormal findings in MR images acquired after epidural injection using the interlaminar approach and the loss of resistance technique with air at the lumbar spine. (Korean J Pain 2017; 30: 281-6)

상백피봉약침요법(桑白皮蜂藥鍼療法)을 포함한 한방치료(韓方治療)로 증상(症狀)은 소실(消失)되었으나 CT추적관찰상(追跡觀察上) 변화(變化)가 없는 요추(腰椎) 추간판(椎間板) 탈출증(脫出症) 1예(例)

이병훈,김철홍,서정철,윤현민,송춘호,안창범,장경전,Lee, Byung-Hoon,Kim, Cheol-Hong,Seo, Jung-Chul,Youn, Hyoun-Min,Song, Choon-Ho,Ahn, Chang-Beohm,Jang, Kyung-Jeon 대한약침학회 2001 Journal of pharmacopuncture Vol.4 No.2

By process of treatment for a case which diagnosed as HNP of left posterolateral aspect of L4/5 disc and treated from the 10th, May 2001 to the 23rd, Jun 2001, the results are as follows. Method & Results : This patient was medicated Hwallaktang-gami, taken acupuncture, phototherapy, TENS, electric acupuncture, exercises, Mori Cortex-bee venom acupuncture. As a result, the patient's clinical symptom were improved but a computed tomagraphy confirmed L4/5 and L5/S1 HNP was not changed as seen on repeated CT scanning. Conclusion : These results suggest that among conservative therapies the oriental medical treatments including Mori Cortex-bee venom acupuncture improve clinical symptom effectively. But in this case, the structure of herniated disc was not changed.

혁신적 신제품의 마케팅전략에 관한 연구

田仁秀,安昶鎬 홍익대학교 경영연구소 2002 경영연구 Vol.27 No.-

황색포도구균의 coagulase형과 항생제감수성 양상의 상관관계

전창호,서헌석,김상경 대한임상병리학회 1996 대한임상병리학회지 Vol.16 No.6

매복된 견치의 Tunnel을 통한 교정적 견인

전정훈,오유향,이난영,이창섭,이상호 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.1

매복된 상악 견치를 위한 외과적 수술을 동반하는 교정치료는 주위조직에 손상을 주지 않고 치열궁내에 적절히 위치시켜야 한다. 이를 위해 매복된 치아의 위치에 따라 다양한 외과적, 교정적 방법이 소개되었으며, 그 방법으로 window procedure, apically positioned flap, closed eruption technique, tunnel traction 등이 있다. 깊은 골연하 매복에서 사용할 수 있는 방법으로 closed eruption technique 그리고 tunnel traction이 있는데, closed eruption technique은 점막 및 치은 하방으로 지나는 견인 와이어의 자극으로 염증 발생 가능성이 높으며 치은퇴축 및 부착 치은의 소실이 발생할 수 있다. 하지만, tunnel traction은 치아의 맹출이 터널을 통해서 유도되어 각화치은에 둘러싸인 채 치조골의 중앙으로 나오게 되므로 치은퇴축이나 치주부착의 소실 없이 적절한 각화치은을 얻을 수 있으며 매복치가 치조골의 중심부로 맹출함에 따라 생리적 맹출과 같은 효과 얻을 수 있다. 본 증례는 깊은 매복을 보이는 상악 견치를 tunnel traction을 이용한 치료를 보고한 것으로, 적절한 방향을 가지고 맹출하였으며 치은퇴축이나 부착치은의 소실이 발생하지 않았다. The impacted maxillary canine is a common problem of which all dental practitioners should be aware. The surgical orthodontic treatment of impacted canines is replaced correction position in dental arch without periodontal damage. Many treatment possibilities have been considered for this goal; window procedure, apically positioned flap, closed eruption technique and tunnel traction. Prognosis for these treatment may be very uncertain in many case(infraosseous impacted tooth). Other steps are required to achieve a satisfactory periodontal outcome. Satisfactory results could be expected if the physiologic eruption pattern is restored by tunnel traction, because permanent tooth erupts through the gingiva near the crest of the ridge so that periodontal damage is reduced. This article report that the surgical orthodontic treatment using tunnel traction is obtained proper position and reduced periodontal damage in facially impacted maxillary canines.