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      • KCI등재

        뇌졸중(腦卒中) 환자(患者) 형태(形態)에 관(關)한 임상연구(臨床硏究)

        윤현민,안창범,송춘호,손인석,장경전,Youn, Hyoun-min,Ahn, Chang-beohm,Song, Choon-ho,Son, In-seok,Jang, Kyung-jeon 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2

        Clinical observation was made on 52 cases of Stroke that were confined through brain CT, MRI scan. The Stroke cases wee classified into the following kinds cerebral infarction, cerebral hemorrhage, cerebellar or brain stem infarction, cerebellar or brain stem hemorrhage. And among the 52 cases of Stroke cerebral infarction was noticed in 75.00%, cerebral hemorrhage in 11.54%, cerebellar or brain stem infarction in 9.52%, cerebellar or brain stem hemorrhage in 3.85%. The ratio between males and females was 1.74:1 in the whole groups of Stroke and most cases were over 60 of age. As the time of hospitalization, most patients hospitalized from 1 day after stroke to 7 days after stroke. And as the course of hospitalization, most patients hospitalized first. Among the preceding disease at the onset of Stroke hypertention was noted in 32.69%, and deabetes mellitus or heart problem was noted frequently(15.39%). Electrocardiography findings were as follows: The normal was noted in 53.85%, the abnormal in 46.15%. And as the abnormal, left ventricular hypertrophy was noted in 17.54%. The predisposing factors or conditions at the onset of brain infarction were usually initiated during the time of sleeping and those of brain hemorrhage chiefly during the time of exercising like overwork or walking etc. It was noted that smoking a pack of cigarette showed highest disease rate(33.33%) among the average of smoking amount of one day in case of man. Prior to attack, the most chiefly complain was dyspnea or discomfort on chest region. And 30.70% of patients had no previous sign. There were a large number of recurrent cases. The first attack was noted in 71.15%, the 2nd attack in 23.08%, the 3rd attack in 5.77%.

      • KCI등재

        Effect of Juglans sinensis Dode extract on chemical hypoxia-induced cell injury in human glioma cells

        윤현민,허재영,안창범,Youn, Hyoun-min,Heo, Jae-yeong,Ahn, Chang-beohm The Korean AcupunctureMoxibustion Medicine Society 2003 대한침구의학회지 Vol.20 No.2

        이 논문(論文)은 활성 산소(ROS)의 작용(作用)을 규명하고 호도약침액(胡桃藥鍼液)이 인간의 신경교종 세포인 A172에서 화학적(化學的) 저산소증(低酸素症)으로 유발된 세포 사멸에 대해 효능이 있는지를 연구(硏究)한 것이다. 화학적(化學的) 저산소증(低酸素症)은 세포내 미토콘드리아의 전자 수송을 방해하는 antimycin A를 가진 배양세포에 의해 유발(誘發)하였다. 화학적(化學的) 저산소증(低酸素症)에 노출된 세포(細胞)는 시간과 그 양에 따라서 세포 사멸의 결과(結果)가 다르게 나타난다. 화학적 저산소증에 의해서 ROS의 생산이 증가하는데 이것은 $H_2O_2$ 소거(消去) Catalase(과산화수소를 물과 산소로 분해하는 효소)에 의해 방지(防止)된다. Catalase는 화학적 저산소증에 의해 유발(誘發)된 세포 사멸을 방지하는데 비해 DMTU는 효과적이지 않다. 지질(脂質)에 녹는 산화방지제 DPPD와 물에 녹는 산화방지제 Trolox는 세포사멸을 방지하는데 효과(效果)가 없다. 호도약침액(胡桃藥鍼液)은 그 양(量)에 의존적으로 저산소증에 의해 유발된 세포 사멸을 방지하는 효과가 있다. 즉 화학적 저산소증으로 유도된 ROS의 발생을 막고, $H_2O_2$로 유도된 세포사멸을 방지하는데 이것은 화학적 저산소증과 $H_2O_2$의해 유도된 세포사멸에 대해 호도약침액(胡桃藥鍼液)이 방지효과(防止效果)가 있다는 것을 의미한다. 이러한 결과(結果)들은 $H_2O_2$가 지질 과산화와는 무관한 메카니즘으로 저산소증(低酸素症)으로 유발(誘發)된 세포사멸을 중재하고, 따라서 호도약침액(胡桃藥鍼液)은 지질막의 과산화를 방지하기 보다는 ROS를 직접적으로 소거(消去)함으로써 방지 효과가 있다는 것을 의미한다. 더구나 화학적(化學的) 저산소증(低酸素症)은 caspase와 무관한 메카니즘으로 apoptosis를 유발(誘發)한다.

      • KCI등재

        음향반향신호의 제거를 위한 개선된 직교투사법

        윤현민,Yun Hyun-min 한국정보통신학회 2005 한국정보통신학회논문지 Vol.9 No.4

        본 논문에서는 음향반향 제거기에서 음성에 대하여 반향제거를 위한 진보된 새로운 기술인 개선된 직교투사법을 제안하였다. 이 결과를 NLMS(normalized least mean square) 적응 알고리즘과 비교하여 보면 개선된 직교투사법은 큰 자기상관을 갖는 신호에 대하여 음향제거 과정이 개선되는 것을 보여준다. 본 논문에서 제안한 개선된 직교투사법의 과정을 검증하기 위하여 프로그램을 작성하여 컴퓨터 모의실험을 실행하여 잡음과 음성에 대해 두개의 적응 알고리즘을 사용하여 수렴곡선을 관찰하였다. 이 두개의 입력신호의 모의실험 결과로부터 본 논문에서 제안한 방법을 음성과 잡음에 적용시킨 결과 빠른 수렴과 ERLE(echo return loss enhancement)가 높음을 보여주었다. This paper proposes the improved orthogonal projection method as a new technique advancing the performance of the echo cancellation for speeches in the acoustic echo canceller. Comparing with the used NLMS adaptive algorithm, it shows that this method improves the performance of the echo cancellation for signals with the large auto-correlation. In order to testify performances of the orthogonal projection method whom this paper proposes, we have coded a simulation program and executed computer simulations. We observed convergence curves by using two adaptive algorithm for noises and speeches. From simulation results for two input signals, the proposed method shows the high ERLE and the fast convergence and the stable operation in case of using speeches as well as noises.

      • KCI등재

        도인기공체조가 여성의 肩臂痛에 미치는 效果

        윤현민,김미영,김이순,임진섭 대한침구의학회 2005 대한침구의학회지 Vol.22 No.1

        Objective : This study intends to identify the effects of the Doin Gigong Exercise on the shoulder-arm pain in Women. Methods : The study was performed with nonequivalent control group pretest-posttest design. A total of 45 subjects were divided into 25 persons in experimental groups and 20 persons in contrastive group by convenience sampling. The data were collected by using questionnaires and measured values from June, 2004, to August, 2004. Results : The results of the study are as follows: 1. The homogeneity testing revealed that most study variables were equally distributed between experimental and control groups. 2. The first hypothesis: The experimental group who performed the Doin Gigong Exercise and who decreased on the subjective symptom scale was supported(t=10.245, p=.000). 3. The scond hypothesis : The experimental group who received Doin Gigong Exercise and who decreased on the subjective pain(VAS) was supported(t=6.816, p=.000). 4. The third hypothesis: The experimental group who received Doin Gigong Exercise and who decreased on the muscular stiffness measured techniques(UNIQUE) was supported (t=7.114, p=.000). Conclusion : Based on the results described above, it is considered that the Doin Gigon Exercise is clearly effective in all an values of the 5 measured. Therefore, the Doin Gigong Exercise can be thought of as effective nursing intervention for the reduction of shoulder-arm pain in women.

      • KCI등재
      • 蜂鍼療法에 대한 考察 및 國內 硏究動向

        尹炫珉,安昌範,曺恩眞 동의대학교 한의학연구소 2001 동의ㆍ경산 한의학 학술대회 Vol.5 No.-

        By classifying and analyzing dissertations from the colleges of oriental medicine of Korea and articles and papers issued in the Korean journals of oriental medicine in last decade on bee venom, we could reach the following conclusions about recent tendency of research on bee venom within the sphere of oriental medicine in Korea. 1. Totally, in the studies of bee venom, more than seven articles of consideration papers and more than fifty experimental case reports have been published. 2. In the field of considerations papers, there were following articles: general and brief summary of bee venom therapy (3 articles), consideration by the help of computer search (3 articles), consideration of old oriental medicine documents (1 article), consideration connected with cancer (1 article). About the experimental case reports, we could find out next ones: report on the effects of anti-inflammation of bee venom (5 articles), on the analgesic effects (4 articles), on the amelioration of circulation of the blood (3 articles), arthritis (7 articles), anti-convulsions (1 article), anti-tumor (2 articles), neuronal activities (6 articles), brain neuronal activities (1 article), and immune response and toxicity (11 articles). 3. In the closer examination on the last articles on immune response and toxicity, they are classified by subjects into the effects on the immunoreaction 6 articles), toxicity and dose (6 articles), the stability (1 article), and research of production of anti-toxin (1 article). 4. By annual statistics, the concentrated and elaborated studies on bee venom started in 1992 with 3 articles, have come to the results of publication of more than 15 articles in 2000, and still in the situation of improvement by quantity and quality. 5. In the earlier period, before 1995, 15 articles on the bee venom's effects on anti-inflammation, analgesia, circulation of blood and 6 articles on characteristics, stability and dose of death of bee venom was published, respectively. Papers connected with arthritis have been issued from the beginning of research to the present day continually. All of five clinical observations have been made only after 1999, and more than 10 reports connected with anti-tumor and neuronal activities, especially, have been printed intensively in the latest days, after 2000.

      • KCI등재

        음향반향신호의 제거를 위한 개선된 직교 투사법

        윤현민 한국정보통신학회 2005 한국정보통신학회논문지 Vol.9 No.5

        This paper proposes the improved orthogonal projection method as a new technique advancing the performance of the echo cancellation for speeches in the acoustic echo canceller. Comparing with the used NLMS adaptive algorithm, it shows that this method improves the performance of the echo cancellation for signals with the large auto-correlation.In order to testify performances of the orthogonal projection method whom this paper proposes, we have coded a simulation program and executed computer simulations. We observed convergence curves by using two adaptive algorithm for noises and speeches. From simulation results for two input signals, the proposed method shows the high ERLE and the fast convergence and the stable operation in case of using speeches as well as noises. 본 논문에서는 음향반향 제거기에서 음성에 대하여 반향제거를 위한 진보된 새로운 기술인 개선된 직교투사법을 제안하였다. 이 결과를 NLMS(normalized least mean square) 적응 알고리즘과 비교하여 보면 개선된 직교투사법은 큰 자기상관을 갖는 신호에 대하여 음향제거 과정이 개선되는 것을 보여준다.본 논문에서 제안한 개선된 직교투사법의 과정을 검증하기 위하여 프로그램을 작성하여 컴퓨터 모의실험을 실행하여 잡음과 음성에 대해 두개의 적응 알고리즘을 사용하여 수렴곡선을 관찰하였다. 이 두개의 입력신호의 모의실험 결과로부터 본 논문에서 제안한 방법을 음성과 잡음에 적용시킨 결과 빠른 수렴과 ERLE(echo return loss enhancement)가 높음을 보여주었다.

      • 帶下의 鍼灸治療에 關한 文獻的 考察

        尹炫珉,安昌範 동의대학교 한의학연구소 1999 동의한의연구 Vol.3 No.-

        The purpose of this reivew was to study acupunture and moxa treatments for abnormal leukorrhea. Normal leukorrhea is always secreted in female vagina. It increased usually by infection(Trichomoniasis and Candidiasis), turmor and so on. In acupunrure therapy meridians of Bladder, Stomach and Spleen were mostly used for them in connection with the functions of each meridians. In particular, Chung-guk(cv3), Kwan-won(cv4) points of Conception vessal Meridian and Samum-gyo point of Spleen meridian are frequently applied in leukorrhea.

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