Comparison of Melanoma Subtypes among Korean Patients by Morphologic Features and Ultraviolet Exposure

( Hong Sun Jang ),( Jee Hung Kim ),( Kyu Hyun Park ),( Jae Seok Lee ),( Jung Min Bae ),( Byung Ho Oh ),( Sun Young Rha ),( Mi Ryung Roh ),( Kee Yang Chung ) 대한피부과학회 2014 Annals of Dermatology Vol.26 No.4

Background: Genetic alterations have been identified in melanomas according to different levels of sun exposure. Whereas the conventional morphology-based classification provides a clue for tumor growth and prognosis, the new classification by genetic alterations offers a basis for targeted therapy. Objective: The purpose of this study is to demonstrate the biological behavior of melanoma subtypes and compare the two classifications in the Korean population. Methods: A retrospective chart review was performed on patients found to have malignant melanoma in Severance Hospital from 2005 to 2012. Age, sex, location of the tumor, histologic subtype, tumor depth, ulceration, lymph node invasion, visceral organ metastasis, and overall survival were evaluated. Results: Of the 206 cases, the most common type was acral melanoma (n=94, 45.6%), followed by nonchronic sun damage-induced melanoma (n=43, 20.9%), and mucosal melanoma (n=40, 19.4%). Twenty-one patients (10.2%) had the chronic sun-damaged type, whereas eight patients (3.9%) had tumors of unknown primary origin. Lentigo maligna melanoma was newly classified as the chronic sun-damaged type, and acral lentiginous melanoma as the acral type. More than half of the superficial spreading melanomas were newly grouped as nonchronic sun-damaged melanomas, whereas nodular melanoma was rather evenly distributed. Conclusion: The distribution of melanomas was largely similar in both the morphology-based and sun exposure-based classifications, and in both classifications, mucosal melanoma had the worst 5-year survival owing to its tumor thickness and advanced stage at the time of diagnosis. (Ann Dermatol 26(4) 485~490, 2014)

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

복강경을 이용한 대장 부분 절제 시행 1예

박재갑,서경석,정회원,김선회,오용석,송인성,박용현 대한대장항문학회 1993 Annals of Coloproctolgy Vol.9 No.1

유전자 알고리즘과 신경회로망을 이용한 고속 확관기의 확관속도 최적화

정원지,김재량,김진한,홍대선,강흥식,김동성 한국공작기계학회 2005 한국생산제조학회지 Vol.14 No.2

This paper presents the optimization of expanding velocity for tube expanding process in the manufacturing of a heat exchanger. In specific, the expanding velocity has a great influence on the performance of a heat exchanger because it is a key variable determining the quantity of tube expanding at assembly stage as well as a key parameter determining overall production rate. The simulation showed that the genetic algorithm used in this paper resulted in the optimal tube expanding velocity by performing the following series of iteration; the generation of arbitrary population for tube expanding parameters, consequently the generation of tube expanding velocities, the evaluation of tube expanding quantity using the pre-trained data of plastic deformation by means of a neural network, and finally the generation of next population using a penalty function and a Roulette wheel method.

이온화가스를 이용한 고농도 유기성 폐수처리에 관한 연구

정팔진,조선영,류재웅 全北大學校 附設 都市및環境硏究所 1999 都市 및 環境硏究 Vol.14 No.1

Livestock wastewater contains high organic and nutrient concentration, and its BOD, COD, SS are high. The treatment of two wastewater by biological method has some problems in the removal of nutrient and organic matter, so it needs for new treatment method. This study carried out concerned the treatment of live stock wastewater by plasma, with Lab scale and pilot scale test. Batch reactor was used in Lab scale test, total reaction time of high and low concentration wastewater was 32hr and 6hr respectively. Continuous reactor was used in pilot scale test, the system is consists of reactor, settling tank. The result of this experiment are summarized as following. · In the Lab scale test, Removal efficiency of COD, TN, TP, SS were around 70 ∼ 99%. · In pre-step, major removal effect is sedimentation and decomposition is major removal effect in post-step.

Maypole Type 편조기의 Guide Track의 동적 모델링 및 해석

정원지,김재량,최선준,김임선 한국공작기계학회 2003 한국생산제조학회지 Vol.12 No.4

Braiding machines of maypole type complex guide tracks. It is not easy to speed up driers while carriers are moving at high speed. This paper presents a new design approach using dynamic analysis and modeling for moving carriers on the guided tracks. The proposed approach will be shown to be effective by using simulation tool, WORKING MODEL 2D^??, for high drivers on new models of braiding machines of maypole type.

大麥의 交配集團에 대한 雜種强勢와 相關關係

鄭元福,李在順,黃弼聖 東亞大學校 大學院 2000 大學院論文集 Vol.25 No.-

This study was carried out to estimate the genetic parameters such as heterosis, heritabilities and genetic correlation in F1 hybrid by the cross combinations of five six-rowed hulled barley: Daejinbori, Gangbori, Tabgolbori, Oweolbori, Albori and three six-rowed naked barley: Songhakbori, Nlssalbori, Hinssalbori and five two-rowed malting barley: Sachun #6, Samdobori, Dusan # 29, Jingkwangbori, Dusan #8. The results obtained were as follows. Oweolbori×Tabgolbori in cross combination of hulled barley showed positive heterosis or heterobeltiosis in leaf length, leaf width, number of grains per spike, and 1,000 grain weight. Songhakbori×Nlssalbori in cross combination of naked barley showed generally positive heterosis and hetrobeltiosis in culm length, leaf width, seed length, seed width, number of grains per spike, and 1,000 grain weight. Oweolbori×Songhakbori in hulled barley×naked barley cross combination showed approximately positive heterosis or hetrobeltiosis in culm length, spike length, leaf length, awn length, seed length, and 1,000 grain weight. Songhakbori×Oweolbori in naked barley×hulled barley cross combination showed generally positive heterosis or hetrobeltiosis in culm length, seed length, and 1,000 grain weight. In Jingkwangbori×Oweolbori and Sachun #6×Songhakbori cross combination heterosis and hetrobeltiosis were high in 1,000 grain weight respectively. When Oweolbori of hulled harley and Songhakbori of naked barley participated in cross combination, heterosis or hetrobeltiosis in productivity was high. Hulled trait in six-rowed barley was dominant against naked trait. Two-rowed trait in malting barley was dominant against six-rowed trait. Heritabilities of cross combination were low for seed length but high for culm length, spike length, length of leaf, leaf width, awn length, 1000 grains weight, and number of grains per spike from 79.21% to 99.87%. Genetic correlation was highly positive in 1,000 grain weight and culm length, 1,000 grain weight and leaf width, 1,000 grain weigh and awn length.

마늘의 Candida sp. 에 對한 抗菌作用에 關해서

鄭在奎,金渭祥,朴佑淳,鄭弼壽 慶北大學校 1962 論文集 Vol.5 No.-

In the previous communication, the growth inhibitory action of garlic on C. albicans was reported and discussed about the candida distribution of Korean people. In the present study, the inhibitory and lethal effects of garlic on candida sp. were studied further detail and the resistance of oral candida sp. isolated from various age groups, to garlic was examined. (1) The growth inhibitory and lethal concentration of garlic juice on standard candida sp. were differ according to the species, however 0.1-0.2% concentraion of garlic juice in Sabouraud media inhibit the growth and 0.6-1.2% concertration of garlic juice exhibit a lethal effect on cardida sp. within 12 hours. (2) The resistance formation or a difference of resistance level of the isolated strain from various age group were not found and candida sp. seems to be not form resistance easily against garlic.

골프장의 잔디 토양에서 살균제 Tolclofosmethyl의 분해

정근욱,우선희,김흥태,사동민,김영기,홍순달,김재정,이재구 한국환경농학회 2004 한국환경농학회지 Vol.23 No.3

Tolclofosmethyl (TCFM) is heavily and annually applied to the turf soils of most golf courses in Gyeongju to control the fungi known to cause the disease brown patch. The soil samples used for the experiment was collected three weeks after the annual application at the end of May in the year 2002. The preliminary results obtained from this study demonstrated that the repeated field annual applications of TCFM to the turf soils of a golf course located in Gyeongju city in the southern area of Korea showed the enhanced degradation of the parent compound TCFM, especially in the surface (0~15 cm) soil rather than the shallow subsurface (15~30 cm) and deep subsurface (30~45 cm) soils, compared to the corresponding surface (0~15 cm) and shallow and deep subsurface (15~30 cm and 30~45 cm) soils of the untreated plot. It appears that microorganisms in the soil may be involved in the enhanced degradation of TCFM.

GIS Vector Map 변환 엔진의 설계 및 구현

최재영,김선미,정영지 원광대학교 2004 論文集 Vol.33 No.-

위치기반 서비스의 기초적인 부분이며 필수적인 부분이 바로 사용자가 자신의 위치에 대한 인지를 명확하게 할 수 있도록 위치를 표시하고 보여주기 위한 지도 데이터 서비스이다. 지도 데이터 서비스를 위해서는 지리정보를 특정 어플리케이션에 의존함이 없이 즉시 볼 수 있는 형태의 포맷으로 변환하는 것이 필요하다. 이를 충족시킬 수 있는 포맷으로 웹브라우저 상에서 바로 볼 수 있는 SVG를 고려할 수 있다. 본 논문에서는 GIS Vector Map의 대표적인 파일 형식인 DXF, SHP, MIF를 분석하였다. 또한, 이들 파일 형식을 공통된 하나의 파일형식인 XML로 변환하여 DB를 구축하고, 구축된 XML 데이터를 SVG로 변환하는 엔진을 구현하였으며 이를 통하여 여 98%이상의 변환 효율을 갖는 결과를 얻을 수 있었다.