간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

자가 면역성 간염에서 자가항체의 발현 양상과 스테로이드 치료의 효과

박기오,채경훈,허원석,강윤세,정재훈,김연수,문희석,이엄석,김선문,이병석,김남재,이헌영 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

목적 : 최근 8년간 본원에서 경험한 자기면역성 간염의 혈액학적 특징과 스테로이드의 치료효과를 알아보고자 본 연구를 시행하였다. 방법 : 1996년 이후부터 2002년까지 충남대학교 병원에서 1999년 International Autoimmune Hepatitis Group(LAHG)에서 제시한 수정 진단 기준안에 의거하여 총 진단점수가 probable 이상에 해당하는 환자들을 대상으로 임상적 특징, 검사실 및 조직 소견과 스테로이드와 azathioprine의 치료 효과를 후향적으로 조사하였다. 결과 : 9예의 환자들은 여성이 78%, 40대가 많았고, 급성 발병이 33.3%, 피로감, 식욕부진 및 황달 등이 나타났으며, 항핵항체가 55.6%에서 그리고 항평활근 항체가 77.8%에서 양성이었고, 동반 질환은 류마치스 관절염이 2예, 특발성 혈소판 감소증 1예, Henoch-Sch nlein 자반증 및 그레브스병이 각각 1예 씩이었다. 7예에 대해서 스테로이드와 azathioprine으로 치료하여 생화학적 임상적 완해가 이루어져서 유효한 치료 결과를 얻었다. 결론 : 자가면역성 간염은 우리 나라에서 원인을 찾을 수 없는 만성 간질환의 경우, 특히 중년여성에서 다른 자가면역성 질환이 동반되었을 때 자가면역성 간염을 의심하여 자가항체 선별검사를 시행해 보아야 할 것으로 생각된다. 향후 다기관 연구를 통하여 좀 더 많은 증례를 모으고 전향적인 연구를 시행하여야 할 필요가 있다. Although autoimmune hepatitis(AIH) is common in western contries, some studties have been reported in Korea. The aim of the study was to analyze the clinical and histological features and expression pattern of the autoantibody and to examine clinical course of AIH in Korea. For 9 patients diagnosed as having AIH in our hospital since 1996, we reviewed medical records and analyzed clinical and laboratory findings retrospectively. They had a probable or definite AIH according to the revised criteria of International AIH group. The mean age was 42.7(21∼68)years and 7(77.8%) were female. Three of them(33.3%) showed acute hepatitis and five of them showed cirrhosis. Fatigue and anorexia were the most frequently complained symptoms(55.6%). Four patients(44.4%) were accompanied with other autoimmune diseases. Antinuclear antibody was detected in 5(55.6%) and anti-smooth muscle antibody was detected in 7(77.8%). Three patients showed focal picemeal necrosis and four showed periportal fibrosis. Among 7 patients who received immunosuppressive therapy, six patients(85.7%) showed initial response. and biochemical and serologic remission were achived in 5(71.4%) and 3(42.8%) patients, AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. AIH should be suspected in female patients with unknown chronic liver disease of unknown etiolgy, especially accompanied with other autoimmune disease. The clinical characteristics of AIH may not be quite different from those of Western countries.

순산소 연소기술에 의한 CO2 회수기술

엄희문 ( Hee Moon Eum ),김성철 ( Sung Chul Kim ) 한국공업화학회 2009 공업화학전망 Vol.12 No.1

재발성 정맥혈전증을 유발한 Antithrombin Ⅲ와 Protein C 복합 결핍증 1예

엄민섭,박연희,설재일,채수엽,유문빈,강기훈,이병수,채은하,박정식,정용환,안승혜,이효진 대한내과학회 2002 대한내과학회지 Vol.62 No.5

Primary venous thrombosis caused by deficiency or qualitative abnormality of antithrombin Ⅲ, protein C and protein S is usually inherited as an autosomal dominant trait. Usually, deep vein thrombosis or pulmonary thromboembolism is developed by such abnormalities, however, mesenteric vein thrombosis is rarely reported. A 27-year-old man with previous history of deep vein thrombosis underwent segmental resection of jejunum due to mesenteric vein thrombosis complicated by necrosis of jejunum. Postoperative investigation disclosed combined deficiency of antithrombin Ⅲ and protein C. His son also showed deficiency of antithrombin Ⅲ. Postoperatively, he is on life-long warfarin therapy without experiencing recurrence of venous thrombosis.

서울시 보건소에서 실시한 관절염환자 자조관리과정 평가

이은옥,서문자,강현숙,임난영,한상숙,송경애,엄옥분,이인옥,김미라,최희정 대한류마티스 건강전문학회 1998 근관절건강학회지 Vol.5 No.2

The purpose of this study was to evaluate the effects of self-help programs which had been conducted at each health center of Seoul using the protocol developed by Korean Rheumatology Health Professionals Society(KRHPS). This program was developed to initially increase self-efficacy, and then to decrease the symptoms and finally to increase the functions of the patients. This study was designed as one group pretest-posttest design. Data were collected by self-administered questionnaires for 140 out of 303 program participants, and only 102 subjects were analyzed because of missing values. The subjects were composed of 25.5% of rheumatoid arthritis patients and 60.8% of degenerative arthritis patients. The results showed that arthritis self-help program was effective in increasing self-efficacy and then improving pain, fatigue, depression, and activities of daily living. But the number of pain sites was not decreased. This result explains that degenerative arthritis patients composed of more than half of the participants has less number of pain sites than rheumatoid arthritis, and their pain was not completely relieved. As a result, it was confirmed that arthritis patients' physical and psychological states con be improved by self-help program in the community. These findings emphasize the implication of this program for each institute to promote health of arthritis patients.

플라즈마 공정에 의해 생성된 부산물의 분석

박태성,엄희문,김경숙,양석란,장경룡 한국화학공학회 2001 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.39 No.3

플라즈마 공정에 의해 생성된 부산물의 비료로써의 활용성 및 첨가제의 필요성과 냉각수등 공정에 필요한 자료를 확보하고자 반응기 하단에 연결된 반응부산물 tank, 반응기 내부 및 반응기 후단에서 시료를 채취하여 분석하였다. 먼저 반응부산물 tank에서 액체상태로 채취한 시료의 경우, SO₄^(2-) 〉NO₃^- 〉NH₄^+ 으로 관찰되었다. 반면에 반응기에 설치된 냉각수를 사용하지 않고 펄스를 인가하여 짧은 시간내에 실험한 후 반응기 내부(반응전극)에서 채취한 시료의 경우, 염화암모늄이 주생성물로 확인되었다. 한편 반응기 후단에서 고체 상태로 채취한 시료의 경우에는 흡습성이 강한 질산암모늄보다는 황산암모늄이 주생성물이므로 부산물을 포집하는데 bag filter도 유용하게 사용될 수 있을 것으로 예상되었다. The samples from 3 different spots were analyzed to get information about the necessities of additives, the needs of cooling water, and the utilities of byproducts as an agricultural fertilizer. First, the liquid sample gathered from the bottom of reactor was showed SO₄^(2-) 〉NO₃^- 〉NH₄^+. Second, the solid sample collected from reactor inside was identified ammonium chloride came from HCl of the exhausted gas. Third, the solid sample stacked in the exhausted plumbing was indicated as a very high ratios of sulfate/nitrate, therefore, a bag filter can be used as a collecting device of byproducts.

발전소 냉각탑 시스템에서의 High C. O. C. 운전에 대한 연구

박광규,엄희문,문전수,박필양 한국공업화학회 2001 응용화학 Vol.5 No.2

Common chemical treatment programs have been developed through pilot tests and field application tests for the high cycles of concentration (C.O.C.) operation in cooling tower systems of combined thermal power plants. The application of common chemical treatment programs, optimized for the high cycle operation, could save the make-up water of about 25,000 ton/day and reduce the inhibitor chemical cost significantly in the cooling tower systems of combined thermal power plants.

소장조영술과 이중풍선 소장내시경검사의 결과에 대한 임상적 고찰

조준영(Joon Yeong Cho),이희정(Hee Jeong Lee),손순룡(Soon Yong Son),이용문(Yong Moon Lee),엄준용(Joon Yong Eum),노현아(Ro Hyun A),김찬민(Chan Min Kim),이원홍(Won Hong Lee),황민호(Min Ho Hwang) 대한영상의학기술학회 2008 대한영상의학기술학회 논문지 Vol.2008 No.-

Purpose : This study is to make a comparative analysis of results of s small bowelseries(SBS) diagnosed radiologically and double balloon enteroscopy(DBE) increased recently. Materials and Methods : From January 2006 to Deoember2007, 78 patients were examined by SBS in company with DBE within three months. The patients were 46 men and 32 women age 18 to 76 years old(mean 42).We made a comparative analysis including a clinical finding, consistency with the clinical finding, and consistency with the two study.

Prediction of Equilibrium Solubility of Carbon Dioxide in Aqueous 2-Amino-2-methyl-1,3-propanediol Solutions

Yoon, Ji Ho,Baek, Jeom In,Eum, Hee Moon 한국화학공학회 2000 Korean Journal of Chemical Engineering Vol.17 No.4

The modified Kent-Eisenberg model was used to predict the solubility of carbon dioxide in aqueous 2-amino-2-methyl-1,3-propanediol (AMPD) solutions over a wide range of solvent concentration (10-30 mass %), temperature (30-60℃), and partial pressure of carbon dioxide (5-1,100 kPa). For more accurate prediction, a new set of experimental data of this system was also presented and used in model calculation. The predicted results by the modified Kent-Eisenberg model were found to be in good agreement with the experimental data. The equilibrium constant, K₁, which represented the deprotonation reaction of AMPD, was expressed as a function of not only temperature but also loading capacity and amine concentration.

CO2 Recovery from Flue Gas by PSA Process using Activated Carbon

Na, Byung Ki,Koo, Kee Kahb,Eum, Hee Moon,Lee, Hwaung,Song, Hyung Keun 한국화학공학회 2001 Korean Journal of Chemical Engineering Vol.18 No.2

An experimental study was performed for the recovery of CO₂from flue gas of the electric power plant by pressure swing adsorption process. Activated carbon was used as an adsorbent. The equilibrium adsorption isotherms of pure component and breakthrough curves of their mixture (CO₂: N₂: O₂=17 : 79 : 4 vol%) were measured. Pressure equalization step and product purge step were added to basic 4-step PSA for the recovery of strong adsorbates. Through investigation of the effects of each step and total feed rate, highly concentrated CO₂could be obtained by increasing the adsorption time, product purge time, and evacuation time simultaneously with full pressure-equalization. Based on the basic results, the 3-bed, 8-step PSA cycle with the pressure equalization and product purge step was organized. Maximum product purity of CO₂was 99.8% and recovery was 34%.