수순(水醇)추출법으로 조제된 오공 약침액의 생리활성 효과

김성철,서근영,이성원,박성주,김재효,안성훈,황성연,Kim, Sung-Chul,Seo, Geun-Young,Lee, Sung-Won,Park, Sung-Joo,Kim, Jae-Hyo,Ahn, Seong-Hun,Hwang, Sung-Yeoun 대한약침학회 2010 Journal of pharmacopuncture Vol.13 No.3

Reactive Oxygen Species(ROS) are continuously produced at a high rate as a by-product of aerobic metabolism. Since tissue damage by free radical increases with age, the reactive oxygen species(ROS) such as hydrogen peroxide($H_2O_2$), nitric oxide(NO). Several lines of evidence provided that ROS appears to cause to develop aging-related various diseases such as cancer, arthritis, cardiovascular disease. Our reserch objective was to examine the in vitro biological activity of Scolopendrid Pharmacopuncture, including the total poly-phenol content, DPPH radical scavenging, ABTS radical scavenging, Superoxide dismutase(SOD)-like activity, Nitrite scavenging ability. The total poly-phenol contents of Scolopendrid Pharmacopuncture was 35.859mg/L. Elctron donation ability on DPPH was 36.82%. The 2,2'-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 84.7%. The superoxide dismutase (SOD)-like activities of Scolopendrid Pharmacopuncture was 44.33%. The nitrite scavenging effects were pH dependent, and were highest at pH 1.5(45.2%) and lowest at pH 6.0(11.3%). We conclude that Scolopendrid Pharmacopuncture may be useful as potential sources of antioxidant.

X선영상증배관의 상대변환계수 측정에 관한 검토

김성철,신성일,이선숙,허준,김성수,Kim, Sung-Chul,Shin, Sung-Ill,Lee, Sun-Sook,Huh, Joon,Kim, Sung-Soo 대한방사선기술학회 1997 방사선기술과학 Vol.20 No.2

For the Evaluation of X-ray image intensifier, we measured radiation dose at input of I. I., brightness and fluorescence at output of I. I. by using X-ray exposure meter, optometer and fluorescence meter for the relative conversion factor. Especially, by using fluorescence meter, we could easily get relative conversion factor without having regulated machine by JIS. Since using, the quality of image intensifier is going down. Consequently, it needs continuous quality maintenance.

초오 약침 개발을 위한 백서 독성 연구 및 생리활성에 대한 연구

김성철,안성훈,김성하,이상관,송봉근,Kim, Sung-Chul,Ahn, Seong-Hun,Kim, Sung-Ha,Lee, Sang-Kwan,Song, Bong-Keun 대한약침학회 2011 Journal of pharmacopuncture Vol.14 No.1

Objective : We investigate toxicity of Aconiti ciliare tuber and antioxidant activity of Aconiti ciliare tuber Pharmacopuncture to develop safe Aconiti ciliare tuber Pharmacopuncture and find out the effect. Methods : In order to investigate toxicity of Aconiti ciliare tuberm, we administered Aconiti ciliare tuberm orally to rats and examined the survival rate, comparing with the survival rate of rats administered by Radix aconitum simmered with Semen Glycine and Radix Glycyrrhizae. We examined the in vitro biological activity of Aconiti ciliare tuber Pharmacopuncture, including the total polyphenol content, and ABTS radical scavenging. Results and Conclusions : The $LD_{50}$ of Radix aconitum simmered with Semen Glycine and Radix Glycyrrhizae was 9.0g/kg, on the other hand, the $LD_{50}$ of Aconiti ciliare tuberm was more than 15g/kg. The total polyphenol contents of Aconiti ciliare tuberm Pharmacopuncture was 2.31mg/L. The 2,2'-azinobis-3-ehtlbezothiazoline-6-sulfonic acid radical decolorization (ABTS) was 10.26%. We conclude that Aconiti ciliare tuberm is not highly toxic, Aconiti ciliare tuber Pharmacopuncture has a little antioxidant effect.

알콜과 각막상피절삭기를 이용한 각막 상피층 분리 및 창상치유 정도 비교

김성철,김웅재,정성근,Sung Chul Kim,Wung Jae Kim,Sung Kun Chung 대한안과학회 2006 대한안과학회지 Vol.47 No.8

Purpose: Laser epithelial keratomileusis (LASEK) is a refractive surgery technique in which the cornea is covered with the epithelial flap after keratectomy. However, there have been reports of tissue damage by the alcohol utilized in this procedure while preparing the epithelial flap, which has led to novel methods. One of these is the mechanical designing of the epithelial flap named epipolis laser assisted in situ keratomileusis (Epi-LASIK). This study evaluates the histologic features and wound healing process of the corneal flap using Epi-Tome, which is the epithelial cutter of the newly introduced Epi-Lasik. Methods: Twenty-four eyes of 12 dogs were devided into two groups. In one group (n=12), 20% alcohol was used and, in the other group (n=12), Epi-Tome (Gebauer, Germany) was used to make a corneal flap. The size change of a fluorescein-stained epithelial defect was followed postoperatively at 6, 12, 24, and 36 hours. Results: The maximum decrease in defect size were observed at 0 to 6 hours in the Epi-Tome group, and from 6 to 12 hours in the alcohol group; the value were 10.01±5.32 mm2 and 9.23±4.75 mm2 respectively. Histologic review revealed that there was less tissue damage and smoother cut edge in the Epi-Tome group compared to the alcohol group, and the adhesion between stroma and epithelium was faster in the Epi-Tome group. Conclusions: Mechanically detached corneal flaps had favorable chances of survival such that re-epithelialization occurred early in the postoperative phase. A few epithelial fragments at a corneal section plane prevent corneal opacification and minimize inflammatory reaction, thus reducing postoperative pain.

PMIPv6에서 사전 인증 기법과 경로 최적화를 이용한 효율적인 핸드오버 기법에 관한 연구

김성철,문일영,조성준,Kim, Seong-Chul,Moon, Il-Young,Cho, Sung-Joon 한국정보통신학회 2010 한국정보통신학회논문지 Vol.14 No.5

PMIPv6 is a network-based mobility support scheme, proposed and standardized by NetLMM WG of IETF. It is proposed to solve problems of conventional mobility schemes, and to improve inefficiency of those. The standard document describes network components and detailed procedures to provide mobility to MN. But it describes only a handover procedure between MAGs, not between LMAs. In order to support seamless connectivity of MN efficiently, a handover procedure between LMAs is necessary. The proposed scheme in this paper utilizes a route optimization procedure to prevent inefficiency of inter-LMA tunneling scheme. At the same time, the proposed scheme utilizes a pre-authentication scheme to reduce handover latency. According to the result of performance evaluations, the proposed scheme greatly reduces handover latency, compared to conventional mobility support schemes. PMIPv6는 IETF의 NetLMM WG에서 표준화를 진행하는 네트워크 기반 이동성 지원 기법으로서, 기존의 단말 기반 이동성 지원 기법의 문제점과 비효율성을 개선하기 위해 제안되었다. IETF에서 공개한 표준 문서는 MN에게 이동성을 제공하기 위한 네트워크 구성 요소와 그 구체적인 동작 및 핸드오버 절차에 대해 서술하고 있다. 그러나 MAG간 핸드오버에 대해서만 정의되어 있고 LMA간 핸드오버에 대해서는 정의되어 있지 않다. 따라서 MN에게 보다 효율적으로 끊김 없는 인터넷 접속을 제공하기 위해서는 LMA간 핸드오버 기법이 함께 사용되어야 한다. 본 논문에서 제안하는 기법은 기존에 제안된 LMA간 핸드오버 기법의 단점인 LMA간 터널을 사용하지 않고, 경로 최적화 절차를 거쳐 효율적인 전송 경로를 사용한다. 또한 핸드오버 지연을 줄이기 위해 사전 인증 기법을 도입하였다. 성능 분석 결과에 따르면 제안하는 기법이 기존의 이동성 지원 기법에 비해 핸드오버 지연을 크게 감소시키는 것을 확인할 수 있었다.

생혈액분석을 통한 저용량 He-Ne 레이저 유침치료에 관한 임상적 연구

김성철,Kim, sung-chul 대한침구의학회 2001 대한침구의학회지 Vol.18 No.3

Objective : The purpose of this study was to investigate the effect of Intravascular Laser Irradiation of Blood(ILIB) by the live blood analysis. Methods : We had analysed the changing forms of the live blood samples with Ultra Darkfield Microscope before and after Intravascular Laser Irradiation of Blood. Results and Conclusion : 1. Nomal Erythrocytes were increased significantly after ILIB by the live blood analysis. 2. Poikilocytes were decreased significantly after ILIB by the live blood analysis. 3. Target Cells were decreased significantly after ILIB by the live blood analysis. 4. Somatid was improved significantly after ILIB by the live blood analysis. 5. Erythrocyte Aggregtion was improved significantly after ILIB by the live blood analysis.

Who' Calling the Shots on State AFDC Policy ; The Governor , the State Legislature or the Bureaucracy ?

김성철,Kyu Cheon Lee,Robert Jay Dilger (Sung Chul Kim) 한국정책학회 1996 한국정책학회 기타자료 Vol.1996 No.2

오공약침(蜈蚣藥鍼)에 대한 연구현황분석(硏究現況分析)과 치료법(治療法)에 관한 연구(硏究)

김성철,Kim, Sung-Chul 대한약침학회 2006 Journal of pharmacopuncture Vol.9 No.2

Objectives : We review a result of studies until the present and suggest the method of medical treatment for the clinical treatment of Scolopendrid Herbalacupuncture. Methods : We analysis the paper of the bibliographic studies, the experiment studies and the clinical studies from 2001 developed Scolopendrid Herbalacupuncture and grope for the course of studies. Results : 1. Scolopendrid Herbalacupuncture is proved the clinical safety by the aninmal and human tests. 2. The pharmacological action of Scolopendra subspinipes mutilans L. Koch is anti-convulsive action, analgesic action, lowering blood pressure, anti-inflammatory action, anti-tumor action and microbe inhibition 3. Scolopendrid Herbalacupuncture has been a fine effect to the entrapment neuropathy and inflammatory. 4. Scolopendrid Herbalacupuncture was thought effective on a acute phase and to the excessive symptoms. The Sub-chronic toxicity experiment observing the response after hypodermic medication over 90 days, The Genetic-mutagenic toxity experiment and the clinical effect studies are necessary.

하나의 GRIN Rod Lens를 이용한 효율적 병렬 광연결

김성철,이욱,이병호,정지채,Kim, Sung-Chul,Lee, Wook,Lee, Byoung-Ho,Jeong, Ji-Chai 대한전자공학회 1997 電子工學會論文誌, D Vol.d34 No.1

We proved the feasibiltiy of a parallel optical interconnection technique using single GRIN (graded-index) rod lens as an intermediate coupling device, which increases the working distance and makes packaging easy. The proposed technique shows relatively less dependency on misalignments. In this paper, for convensience of experiments, we applied this method to 4-channel coupling between two fiber arrays, and compared it with butt-coupling and the method of using ball lens. The comparison shows the feasibility of adopting the proposed method to the parallel interconnection between a laser diode array and an optical fiber array.

동일 농도0.1mg/ml)의 Sweet Bee Venom과 봉약침의 퇴행성 슬관절염에 대한 임상연구

김성철,나원민,이성용,장은하,임승일,Kim, Sung-Chul,Na, Won-Min,Lee, Sung-Young,Jang, Eun-Ha,Lim, Seung-Il 대한약침학회 2008 Journal of pharmacopuncture Vol.11 No.1

Objectives : To verify pain relief effects and allergy inhibitory action for the osteoarthritis of the knee joint in Sweet Bee Venom in which allergy causing enzyme is removed. Methods : We randomly allocated 30 participants to treatment group Sweet Bee Venom and Bee Venom. Outcomes on pain reduction were measured by 100mm VAS(Visual Analog Scale). And we recorded into details allergic responses during Pharmacopuncture treatment. Results : Whole body condition and pain rate through VAS measurement were improved significantly in 2 weeks. We could get difference in pain score of two Pharmacopuncture groups significantly in 2 weeks. Sweet BV group($0.1{\beta}mg/m{\ell}$) showed superior reduction in pain compared to the BV group($0.1{\beta}mg/m{\ell}$) significantly. And other allergic responses such as edema, itchiness, pain were significantly lower in the Sweet BV group.