자연산 점몰개, Squalidus multimaculatus Hosoya et Jeon의 새인두흡충, Clinostomum complanatum (Rudolphi, 1814) 감염

박명애 ( Myoung Ae Park ),서정수 ( Jung Soo Seo ),정승희 ( Sung Hee Jung ),최희정 ( Hee Jung Choi ),전은지 ( Eun Ji Jeon ),지보영 ( Bo Young Jee ),이완옥 ( Wan-ok Lee ),우승호 ( Sung Ho Woo ),이은혜 ( Eun Hye Lee ) 한국어병학회 2011 한국어병학회지 Vol.24 No.2

경상북도 영덕군의 하천에 서식하는 점몰개 spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon)의 근육에서 새인두흡충 Clinostomum complanatum (Rudolphi, 1814)의 피낭유충이 발견되었다. 감염된 점몰개는 "yellow grub"인 기생충의 피낭유충으로 인해 표면이 울퉁불퉁하게 보였으며, 수면위에 힘없이 유영하였고 일부 폐사한 개체도 발견되었다. 분리된 탈낭유충의 형태는 혓바닥 모양이었으며, 크기는 2.85~5.89 mm×0.8~1.99 mm였다. 어체당 1~98 개의 피낭유충을 분리하였으며 평균 감염수는 25개로 나타났다. 특히, 성어크기인 평균 7 cm 정도의 점몰개는 100% 감염되어 있었다. 본 연구는 한국의 자연수계에 서식하는 어류에서 C. complanatum 의해 질병이 발생하고 폐사가 일어난 첫 보고이다. The metacercariae of Clinostomum complanatum (Rudolphi, 1814) were isolated in the whole body muscle of wild freshwater fish, spotted barbel gudgeon (Squalidus multimaculatus Hosoya et Jeon) from the local river in Yeongdeok, Gyeongsangbuk-do, Korea. The infected fish with bumpy body surface by "yellow grub" showed erratic swimming behavior and some fish were died. The isolated excysted metacercariae were tongue shaped and 2.85~5.89 mm × 0.8~1.99 mm in size. 1~98 metacercariae were isolated in individual fish and mean infection intensity was 25. All examined adult spotted barbel gudgeon sizing 7 cm in body length were infected. This is the first report of disease outbreak and mortality caused by C. complanatum infection in wild freshwater fish in Korea.

청소년 도덕적 동기화 검사 도구 개정 연구(2차년도)

전종희 ( Jong Hee Jeon ),이인재 ( In Jae Lee ),김영한 ( Young Han Kim ),박균열 ( Gyun Yeol Park ),윤영돈 ( Young Don Yoon ),류숙희 ( Sook Hee Ryue ),홍성훈 ( Seong Hoon Hong ) 한국윤리교육학회 2013 윤리교육연구 Vol.0 No.29

본 연구는 J. Rest의 4구성요소 모형을 바탕으로 1차년도(2011년)에 개발된 도덕적 동기화 검사를 보다 신뢰롭고 타당한 도구로 개정하는 것이다. 따라서 선행연구를 보완하여 도덕 동기화의 구성 요소를 도덕지향성과 도덕적 정서귀인 등 두 항목으로 재설정하고, 스토리와 문항을 수정하였다. 개발된 세 개의 스토리(과제, 놀이공원, 작품) 별로 신뢰도를 분석한 결과, 전반적으로 .90 내외의 높고 수치를 보였다. 응답의 편포성을 완화하기 위해 2차년도에는 7점 척도를 사용하였다. 예비조사를 위해서는 전국 중학교 2학년생 409명을 대상으로 했고, 본조사를 위해서는 전국 6,216명의 중학교 2학년생을 대상으로 실시하였다. 개발된 검사도구의 신뢰도계수(문항 내적 일치도인 크론바흐 알파)는 .90이상으로 신뢰할만했다. 타당도를 검증하기 위하여 요인분석을 실시한 결과, 과제 스토리와 놀이공원 스토리의 일부 문항이 가정한 요인으로 잘 묶이지 않았는데 이 문항들을 제거하고 요인분석을 다시 실시해본 결과 기대하는 바를 충족했다. 그리하여 2차년도 연구를 통해 최종 스토리는 총 세 개(과제, 놀이공원, 작품)로 확정되었고, 각 스토리별 문항수는 과제 9개 문항, 놀이공원 9개 문항, 작품 10개 문항으로 총 28개 문항으로 확정되었다. 본 연구를 통해 수정 확정된 도덕적 동기화 검사도구는 상당히 안정적인 신뢰도와 타당도를 확보하였기에, 향후 우리나라 청소년의 도덕적 동기화 능력을 측정하기 위한 검사도구로 활용되기에 적절할 것으로 판단된다. The study aims to revise Moral Motivation Test I which was set for adolescents based on Rest`s four component model in 2011 and make standardized final morality test. In theory, this study is based on 4 components theory of James Rest who invented DIT (Defining Issues Test) to measure the moral judgment. The 4 components are composed of moral sensitivity, moral judgment, moral motivation, and moral character (or moral implementation, moral action). This study focused on moral motivation. This 2nd year study could get some significant outcomes. To make test form, 3 components relating teams have closely exchanged informations. Because teams have to share same real life stories as follows: “homework inspect”, “on going to park”, “broken art work”. The questionnaire used seven likert type to lessen the far epistemological tendency. To represent moral motivation, research team used moral orientation, moral emotion attributions. To get final form of morality test, this study was made two sequential steps. First one was pre-test which was for 409 respondents. Second main one was for 6,216 respondents. For moral motivation, the reliability was highly coefficient with Cronbach`s alpha(>.90). The validity was also much improved and stable. But just in the story “homework inspect”and “on going to park”, the factor analysis shows a little bit limitation result. Eliminated those questions, the result of factor analysis was more stable and reliable. Through these processes, to test moral motivation, this study shows 3 stories and 28 questions. And this recommends that just one simple story might be developed for one component(moral motivation).

청소년 도덕적 품성화 검사 도구 개정 연구(2차년도)

류숙희 ( Sook Hee Ryue ),이인재 ( In Jae Lee ),김영한 ( Young Han Kim ),박균열 ( Gyun Yeol Park ),홍성훈 ( Seong Hoon Hong ),전종희 ( Jong Hee Jeon ),윤영돈 ( Young Don Yoon ) 한국윤리교육학회 2013 윤리교육연구 Vol.0 No.29

본 연구는 한국 청소년들의 도덕적 품성화 능력을 측정하기 위한 검사 도구를 개발하기 위한 것으로 2011년도에 개발된 검사 도구를 수정 및 보완한 것이다. 즉, J. Rest가 주장한 도덕성의 제4요소인 도덕적 품성화에 관한 선행연구들을 체계적으로 분석하여 도덕적 품성화의 개념을 보다 명확히 하였고, 1차년도에 설정한 도덕적 품성화의 구성 요소를 개인품성과 관계품성의 두 항목으로 재설정하였다. 또한 검사의 신뢰도와 타당도를 높이기 위해 기존의 스토리와 문항을 수정하였다. 응답의 편포성을 완화하기 위해 2차년도에는 7점 척도를 사용하였다. 예비조사는 전국 중학교 2학년생 409명을 대상으로 실시되었고, 본조사는 전국 6,216명의 중학교 2학년생을 대상으로 실시되었다. 개발된 검사도구의 신뢰도계수(문항 내적 일치도인 크론바흐 알파)는 .90이상으로 신뢰할만했다. 타당도를 확보하기 위해 요인분석을 실시했는데, 도덕적 품성화 능력 검사는 1개 문항을 제외하고 모든 문항이 예정된 요인으로 묶였다. 그리하여 2차년도 연구를 통한 최종 스토리는 총 세 개(과제, 놀이공원, 작품)로 확정되었고, 각 스토리별 문항수는 과제 10개 문항, 놀이공원 9개 문항, 작품 10개 문항으로 총 29개 문항으로 확정되었다. 2차년도 연구결과 개정된 검사 도구는 2011년 검사 도구에 비해 더 안정된 검사도구로서 향후 청소년의 도덕적 품성화 측정을 위한 연구와 실무에 활용될 수 있을 것이다. The study aims to revise Moral Character Test I which was set for adolescents based on Rest`s four components model in 2011 and make standardized final morality test. In theory, this study is based on the four components theory of James Rest who invented DIT (Defining Issues Test) to measure the moral judgment. The four components are composed of moral sensitivity, moral judgment, moral motivation, and moral character (or moral implementation, moral action). This study focused on moral character. This 2nd year study could get some significant outcomes. To make test form, 3 components relating teams have closely exchanged informations. Because teams have to share same real life stories as follows: “homework inspect”, “on going to park”, “broken art work”. The questionnaire used seven likert type to lessen the far epistemological tendency. To represent moral character, research team used personal character and interpersonal character. To get final form of morality test, this study was made two sequential steps. First one was pre-test which was for 409 respondents. Second main one was for 6,216 respondents. For moral character, the reliability was highly coefficient with Cronbach`s alpha(>.90). The validity was also much improved and stable. But just in the story “on going to park”, the factor analysis shows a little bit limitation result. Even though, 1st and 2nd researches have common weak point which is highly dependent upon not factor but story. Through these processes, to test moral motivation, this study shows 3 stories and 29 questions. And this recommends that just one simple story might be developed for one component(moral character).

저강도 초음파 및 레이저를 이용한 장관골 불유합의 치료

전인호,오창욱,김성중,경희수,박일형,박병철,인주철,여준영 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목 적: 저강도 초음파는 인체 및 동물 실험에서 골조직에 낮은 미세한 물리적 압력을 가하여 골절의 치유에 유리한 영향을 주고, 레이저 (LASER)는 심부 조직에 혈류를 증가시키고, 세포 내 잠재된 에너지를 증가시키는 것으로 알려져 있다. 이에 저자들은 임상적으로 확진된 장관골 붕류합의 치료에 있어 펄스형 저강도 초음파와 레이저를 적용하고 그 효용성을 알아보고자 하였다. 대상 및 방법: 초음파/레이저의 치료 효과를 비교하기 위하여 장관골 불유합으로 확진된 16예 중 8예는 연구군으로 골이식술 후 저강도 초음파와 레이저 치료를 추가하였고 대조군 8예에 대해선 일반적인 골이식술만 시행하여 조사하였다. 남자가 11예, 여자가 5예, 평균 연령은 41.7세 (19~62세)였고, 불유합 부위는 대퇴골이 10예, 경골이 6예였다. 첫 수상으로 인한 골절 후 초음파/레이저 치료까지 시간(골절 연력)은 평균 502일이었다. 결 과: 8예의 연구군에서는 완전 골유합이 6예에서 이루어졌으며 유합까지의 시간은 평균 141일 (101~202일)로 나타난 반면, 8례ㅢ 대조군에서는 5예에서 골유합이 이루어졌고, 유합까지의 시간은 평균 240일 (183~283일)이었다. 결 론: 저강도 초음파/레이져 골절 치료기가 반복된 수술로 인한 난치성 장관골 불유합의 치료에 있어 골이식술과 함께 사용될 경우 긍정적인 효과가 있었고, 특히 최초 가골 형성에 있어 대조군에 비해 그 시간을 줄일 수 있었따. Purpose: Low-intensity, pulsed ultrasound (LIPUS) has demonstrated a stimulation and acceleration of the normal fracture-repair process in cellular bases as well in animal and human models. In this study, the adjunctive effect of LIPUS and LASER was investigated in established nonunion of the long bones. Materials and Methods: Study group consisted of eight patients to whom conventional bone graft and adjunctive LIPUS and LASER was applied. On the other hands, eight patients in the control group underwent bone graft only. Eleven men and five women were included in this study and the average age of the patients was 41.7 years (range, 19~62 years). Six of the tibias and ten of the femurs met the criteria for established nonunion. The average fracture age, the post-fracture period before the start of LIPUS/LASER treatment, was 502 days. Results: Seven of the ten nonunions who were treated by LIPUS and LASER healed completely in an average treatment time of 141 days (range, 101~202 days) and otherwise, in control group, five of the eight nonunions healed completely, in 240 days (range 183~283 days). Conclusion: This clinical study showed a positive effect of LIPUS and LASER on the rate of osseous repair, especially accelerated time to initial callus cortical bridging compared to that of conventional treatment.

심전도 모니터링 계측 시스템의 개발에 관한 연구

박찬원,전찬민,박희석 강원대학교 정보통신연구소 2004 정보통신논문지 Vol.8 No.-

A wearable electrodiagram(ECG) monitoring system is a widely used non-invasive diagnostic tool for ambulatory patients who may be at risk from latent life-threatening cardiac abnormalities. In this paper. we have a portable ECG monitoring system with conductive fiber characterized by the small-size and the low power consumption. The system consists of conductive fibers, one-chip microcontroller, ECG preprocessing circuit, and monitoring software to record and analyze in PC. ECG preprocessing circuit is made of pre-amplifier with gain of 10, band-pass filter with bandwidth of 0.5-120% and 2.5V offset circuit for A/D conversion. ECG signals obtained by sensor are corrupted by noises such as a baseline wandering, 60Hz power noise and interference noise by body movement. For cancellation of noises in signals obtained by conductive fiber, we used the wavelet decomposition of wavelet transforms in MATLAB toolbox.

흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

소아 간질 아동 어머니의 양육 스트레스 및 부모효능감

박수빈,유한익,전정원,최순호,왕희령,김건우,김진용,고태성 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : While parents who foster children with epilepsy would have considerable parenting diSiculties, the parenting stress and sense of competence have not been investigated. We investigated matemal parenting stress, Parenting satisfaction and sense of parenting competence in children with seizure disorders, and the associations with seizure-related variables. Methods : Mothers of 79 children with seizure disorders (41 boys, 38 girls ; mean age, 9.9±2.3 years) and 79 healthy comparison subjects matched for age and sex were recruited for this study. The Korean version of the Parenting Stress Index (K-PSI-SF) and the Parenting Sense of Competence (K-PSOC) were used to assess parenting stress, parenting satisfaction and parenting effcacy. Results : Mothers of children with seizure disorders showed higher scores on stress related to difficult child and child leaming and parenting anxiety compared to mothers of healthy children. In addition, scores on stress related to parental-child interaction and child leaming were significantly associated with parental economic status. Scores on stress from parental-child interaction was also correlated with seizure severity, and stress from child leaming was correlated with seizure type. Sense of parenting competence and anxiety scores were correlated with patemal educational status, respectively. Conclusion : These fndings suggest that mothers of children with epilepsy have greater parenting stress and anxiety and social and seizure-associated factors may affect the parenting stress and anxiety.

Hydantoin환의 가수분해반응 및 O-알킬화반응을 이용한 새로운 A1ky1 α-Anilinophenylacetate 유도체의 합성

박명숙,최희전,박해선,권순경 德成女子大學校 藥學硏究所 2002 藥學論文誌 Vol.13 No.1

For the development of new synthetic method for unnatural amino acid esters, alkyl α-anilinophenylacetates 4a-i were synthesized through base-catalyzed hydrolysis of 1,5-diphenylhydantoins 1a-b in methanol and O-alkylation of sodium α-anilinophenylacetate 3 with alkyl halides in DMF. Even though hydrolysis of hydantoin ring was undertaken under about 30-40℃ in methanol, the hydantoic acid sodium salt 2 was continuously converted to the sodium α-anilinophenylacetate 3. All synthetic process from hydantoin to alkyl α-anilinopheny lacetates could be carried out in one-pot without isolation of intermediates.

Retinol 국소도포에 의한 눈가주름 제거효과

전희대,이성열,이혜진,박영립,이종석,황규왕 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

In 3 months randomized, double-blind, vehicle-controlled study of retinol (vitamin A 0.1%-3000IU/g) in the treatment of photoaging skin, especially eye wrinkles. 24 patients applied retinol contained cream to the both eye wrinkles and vehicle cream(placebo) to the same site. Half of the patients received retinol contained cream and half received vehicle cream(placebo). All 24 patients who completed the study showed statistically significant improvement in photoaging eye wrinkles on the retinol contained cream treated group, but not on the vehicle treated group. Eight of the 12 patients who received retinol contained cream to eye wrinkles had improvement in photoaging, whereas only three of the 12 patients who received vehicle cream(placebo) improved. In retinol contained cream group, there is a some relationship between water contents and effects. In other words, as water contents were the higher, effects were the better. The side effects were limited to mild irritation of retinol contained cream treated skin. Retinol contained cream appeared to be safe and effective in the treatment of eye wrinkles.

악성림프종 환자에서 복합화학요법으로 유발된 백혈구 감소증에 대한 인형 재조합 과립구 집락형성-촉진인자(rhG-CSF: Neutrogin)의 효과

박성규,전진우,기신영,유병우,김홍수,백승호,원종호,홍대식,박희숙 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Clinical effects of rhG-CSF were investigated in 17 patients receiving chemotherapy for non-Hodgkin's lymphoma. Patients were given G-CSF 2㎍/㎏/day after 2nd cycle chemotherapy for least 14 consecutive days, and clinical and laboratory results were compared to results of the first cycle. Treatment with G-CSF resulted in increase of mean WBC count(952.9±152.2㎜³vs 1882.4±350.4/㎜³) and neutrophil count(212.9±53.0/㎜³vs 841.5±238.0/㎜³), reduced the duration of leukocytopenic days(12.4±1.3 days vs 5.5±1.0 days, WBC count less than 4000/㎜³) and neutropenic days(4.5±0.9 days vs 2.3±0.7 days, neutrophil count less than 500/㎜³), and reduced the duration of neutropenic fever(5.8±1.1 days vs 0.9±0.5 days). The side effects of G-CSF were not so significant. These results demonstrated that G-CSF is safe and useful for the treatment of neutropenia induced by anticancer chemotherapy of non-Hodgkin's lymphoma and reducing the incidence of febrile periods and duration of antibiotic administration.