急性메칠水銀 中毒時 白鼠組織의 經時的 變化와 마늘의 防禦效果에 關한 實驗的 硏究

李文基,車喆煥,裵恩相 고려대학교 의과대학 1985 고려대 의대 잡지 Vol.22 No.1

This study was undertaken to examine the protective effect of garlic in heavy-metal poisoning. Using sufficient amount of garlic which is thought to contain disulride compound (diallyldisulfide) and sulfhydryl group(such as glutathione), a chronological observation wasmade to determine the effect of garlic in removing heavy metal from tissues and restoring the normal histological architecture in organs of rats poisoned by heavy metals. A total of 80 albino rats were divided into two groups; a garlic-treated group and a non-treated group. As pretreatment, 5mg/kg of methyl mercury were injected into the peritoneal cavities of the rats of both groups for 8 days to induce an acute mercury poisoning. The garlic-treated group was fed with commercial feed containing 6.7% of garlic and the non-treated group was fed without garlic from the first day of pretreatment. Blcod was collected from all the rats on 10th, 30th, 50th, and 70th day after a final injection of methyl mercury and centrifuged to collect erythrocytes. At the same time, liver, brain and kidney were ectomized to study the total amount of accumulated mercury and the pathological changes of the tissues in those organs. The results are as follows : 1. It is certain that garlic has contributed in the remova1 of mercury accumulated in the organs. The half-reduction period of mercury in erythrocytes liver, and kidney appeared abou 50 days after the final injection of methyl mercury. Although the removal of mercury from the tissues increased remarkably in the garlic treated group, the removal of mercury from the brain tissue appeared to be below that of other oygans. Compared with the mercury in tissues on the 10th day, the remaining amount of mercury 70 days after the final injection was 23% in erythrocytes 20% in the liver, 41% in the kidney and 50% in the brain. 2. As for the recovery process of histopathological damages in the kidney of mercury poisoned rats, the non-treated group showed dilatation of nephrons and denudation of epitherial lining on 10th and 30th days, and not until the 50 day was the epithilial regeneration seen. On the contrary, in garlic-treated group, the recovery along with the regeneration of the epithelial cell appeared clearly on-l0th day, and on 30th day the mercury poisoned renal tubule was restored to its normal architecture. 3. The moderate demyelinization in white matter of the, brain appeared by 10th day and progressed with time and neuronal necrosis in granular and Purkinje layer was seen by 50th day in the non-treated group. The degree of damage, however, was mild and the regeneration time was short in the garlic-treated group.

규제순응의 제고 : Policy Alternatives for better Regulation

李哲圭 水原大學校 2005 論文集 Vol.23 No.-

The institutional framework for regulatory reform was completed in 1998 as the government enacted the Government Regulation Act and established the Regulatory Reform Committee under the President. As a result, enormous quantifies of regulation have been reduced oyer the last seven years since its establishment. Most of People and business enterprises, however, disagree with the result. According to recent survey. 79% of enterprises answered that government regulation had not been reformed or changed. Some of them even believe it had been increased. The huge evaluation gaps exist between Government and business enterprises. Government insists enduring regulations are inevitable but business institutions do not endorse. The former believes that only the reasonable regulatory measures are being implemented, but the latter not. Government, under these circumstances, should make an effort to improve the degree of regulatory compliance. The Regulatory Impact Analysis has to be thoroughly fulfilled, if necessary. Moreover the regulation makers should consider other different points of views. including those of the regulated institutions. A regulation which is not willingly complied. should be withdrawn.

體格과 體力의 發達 및 相關에 관한 統計學的 硏究 : 女子中高等學生을 中心으로 with girls' Junior & Senior High School Students as the Central Figures

李鐵煥 진주여자전문대학 1983 論文集 Vol.5 No.-

1. the Method of research The objective of this research is to consult and coach the selection of sports items according to ages and individual difference, and to make an offer the reference materials to prospect this individual physique and the physical fitness with the knowledge of the growth and developmental process of the physique and physical fitness of junior high school girls in expansion period and senior high school girls in adolescence by evaluating and analyzing the physique and the physical fitness of twelve-seventeen years old girls randomly sampled from "S" girls junior & "S" girls senior high school in MASAN 1) the developmental condition of physique. 2) the developmental condition of physical fitness 3) the relation of physique reciprocity. 4) the relation of physical fitness reciprocity. 5) the relation of physique & physical fitness. 6) the regression equahon between physique reciprocity. 7) the regression equation of physical fitness items to physique. 2. the result of research. 1) in the physique development. Generally it seems to be a noticeable development from 12 to 15, but thereafter the development become to be dull. 2) in the physical fitness development. Strength and agility are developing continously but the rest seem to develop to some extent and regress continously 3) in the relation of physique reciprocity. It seems to be nearly a high positive correlation. 4) in the relation of physical fitness reciprocity. The most of items have a positive or negative correlation. 5) in the relation of physique and physical fitness A particular aspect is that both of the grip strength and physique are to have a little positive correlation. 6) in the physique and the reciprocity of physical fitness items to physique. A certain physique condition offers some references to evaluate another physique condition or basic physical fitness

만성 정신분열병 환자에서 지연성 운동장애와 음성증상 및 인지기능 장애와의 연관성

심주철,반철식,성기수,이정구,정도운,정청,윤진상,김영훈 대한신경정신의학회 2000 신경정신의학 Vol.39 No.4

연구목적: 정신과 전문병원에 입원해 있는 만성정신분열병 환자들을 대상으로 첫째 지연성 운동장애의 유병율과 위험인자들을 조사하고, 둘째 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성을 조사하고자 한다. 방법: 연구대상자는 마산동서병원에 입원 중인 환자 중 DSM-IV의 정신분열별 진단기준에 부합하며, 최근 3개월 이상 동일 용량의 항정신병약물 복용한 271명(남자 174명, 여자 97명)의 환자들이었다. 지연성 운동장애에 대한 평가는 Abnormal Involuntary Movement Scale(AIMS)을 이용하였고, DSM-IV와 Sc-hooler와 Kane(1982)의 진단기준 양자에 부합하는 환자들만을 지연성 운동장애군으로 분류하였다, 정신 분열병 정신병리에 대한 평가는 Brief Psychiatric Rating Scale(BPRS)와 Schedule for the Deficit Syndrome(SDS)을 이용하였고, 인지기능에 대한 평가는 Mini-Mental Status Examination(MMSE)을 이용하였다. 결과: 지연성 운동장애의 유병율은 50.9%이었고, 50세 이상, 남자에서 높았다. 그러나 입원기간과 항정신병 약물의 일일 사용량에 따른 차이는 없었다. 지연성 운동장애의 호발부위는 혀, 상지, 입술과 입 주위의 순이었다. BPRS 총점 및 소항목 척도점수와 SDS 척도점수는 지연성 운동장애의 유무에 따른 차이가 없었다. MMSE 총점 및 소항목 점수도 지연성 운동장애의 유무에 따른 차이가 없었다. 결론: 평균입원기간이 9년 이상인 만성정신분열병 환자들에게서의 지연성 운동장애의 유병율은 50.5%이었고, 연령이 가장 의미있는 위험인자임을 확인했다. 만성정신분열병 환자들이 주 대상인 본 연구에서는 지연성 운동장애와 정신분열병의 음성증상 및 인지기능 장애와의 상관성은 입증하지 못했다. Objectives: The purpose of present study was to determine the prevalence rate of tardive dyskinesia and to search for its risk factors in chronically institutionalized schizophrenic subjects. We also examined the relationship between tardive dyskinesia and both negative symptoms and cognitive impairments in the same subjects. Methods: Subjects were 271 in-patients(174 males, 97 females) at Masan Dongsuh Hospital. They met DSM-IV criteria for schizophrenia and had been taking fixed doses of antipsychotics for at least 3 months. Tardive dyskinesia was assessed by Abnormal Involuntary Movement Scale(AIMS). Cases of tardive dyskinesia were ascertained by the criteria of Schooler and Kane (1982) and DSM-IV. The rating of psychopathology was acquired using Brief Psychiatric Rating Scale(BPRS) and Schedule for the Deficit Syndrome(SDS) and the assessment of cognitive function using Mini-Mental State Examination(MMSE). Results: The prevalence of tardive dyskinesia is 50.9% and the frequency of tardive dyskinesia was high est in male above the age of fifty. But there was no statistically significant relationship between the frequency of tardive dyskinesia and both the length of hospitalization and the daily dose of antipsychotics. The frequency order of abnormal movement in the patients with tardive dyskinesia was as follows : tongue, upper extremities, lips and perioral area. We couldn't find any significant difference in the total and subscale scores of BPRS between the groups with and without tardive dyskinesia. There were no differences in MMSE scores between the groups with and without tardive dyskinesia. Conclusion: This study gave us that the prevalence of tardive dyskinesia was high in chronically institutionalized schizophrenic inpatients and that age was the most significant risk factor of tardive dyskinesia. The relationship between tardive dyskinesia and both negative symptoms and cognitive impairment, however, was not revealed.

통합게이지 이론과 QCD이론의 차이에 관한 연구

이철세,이성서 培材大學校 1984 論文集 Vol.5 No.-

The differential cross sections for the process W+P→γ+ hadrons in the Quantum chromody-amics and in the Unified gauge theory have been calculated. These calculations have been carried out in the parton picture with impulse approximations. The quark contributions to the differential cross sections show that the predictions from the broken color gauge theory are about 1.5 times larger than those from the quantum chromodynamics.

씨름의 呼稱에 關한 硏究

李喆熙,李勇仁 忠南大學校體育科學硏究所 1983 體育科學硏究誌 Vol.1 No.1

In 1905, Kakjoto(a painting of Ssireum) was discovered on the inside of the wall of an old tomb of Kokuryo called Kakjochong by unearthing an old tomb in Tonghua province in Manchuria. Since then, it has been studied by scholars who are studying physical education as well as history throughout China, Korea, Japan, and so on. Their conclusions are as follows: 1. Tonghua province in Manchuria was Hwantosansung, which was old capital city of Kokuryo when the tomb was built. 2. The buried person is of Kokuryo and it is conjectrued that the tomb was built around 40 B.C, 3. Ssireum was termed Kakcho, Kokcho, Sangbak, Kakji, Jaengkyo, Kakkyo, Yokyo, Kaklyok, Kakki, Kakhi, and so on, which is considered as mixed terms of the three different terms: Chinese Shegiu, Japanese Smou and Korean Ssireum. This study attempted to seek the term of genuine Korean Ssireum by means of Korean, Chinese and Japanese literatures. The following shows their findings: 1. In China, it was termed Kakcho, Sangbak, Jaengkyo, Kakji, Kakkyo, Kokcho, and Solkak. 2. In Korea, it was termed Kaklyok, Kakcho, Yokyo, and Kakhi. 3. In Japan, it was termed Kakcho, Kaklyok and Sangbak.

大規摸 染色工業團地 廢水의 綜合處理에 關하여

曺秉樂,李種達,朴永圭,李哲熙,李武康 嶺南大學校 環境問題硏究所 1981 環境硏究 Vol.1 No.1

In this study, a method of treating waste water from the Bisan Dyeing Industry complex has been developed. This process will be used as a model for treating waste water from the future large-scale dyeing industy complex. If the concentrated dyeing waste water may be seperated from the scouring waste water the C-2 process is the most economical to treat the concentrated dyeing waste water first by the coagulation precipitation process and the scouring waste water mixed with the effluent of coagulation precipitaion next by the activated sludge process. When it is impossible to seperate the concentrated dyeing waste water from scouring water for the Biasn Dyeing Industry complex, the B-2 process treating by the activated sludge process following coagulation precipitation with alum can be applied.

충남대학교 기초과학분야의 효율적 육성에 관한 연구

윤화중,진성일,윤민중,윤혜수,이영하,최철규,이천배,신대현 충남대학교 자연과학연구소 1986 忠南科學硏究誌 Vol.13 No.2

Chungnam National University (CNU) is located in Daeduk Science Town, a center of science and technology in Korea, and it is expected to play an important role in the development of science in Korea. With this in mind, the basic natural sciences at CNU should be more actively supported in both education and research. Accordingly analysis and comparison of the basic science program at major college in Korea as well as those in the USA and Europe has been performed. The current cooperative relationship between CNU and research institutes in the science town has also been analyzed. This study has resulted in propositions to make more efficient the upbringing of the basic sciences at CNU, by focusing on the following points ; a) to improve academic affairs, b) to make graduate studies substantial, c) to secure highly qualified faculty members, d) to increase cooperation in research between CNU and reserch institutes, e) to enlarge research laboratories and acquire more equipment and facilities.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

우린라 성인 건강 검진자에서 배변습관에 관한 연구

이풍렬(Poong Lyul Rhee),이종철(Jong Chul Rhee),최규완(Kyoo Wan Choi),김은주(Eun Joo Kim),박창영(Chang Young Park),손정일(Jong Chul Rhee),전우규(Woo Kyu Cheon),김병익(Byeong Ik Kim),정을순(Eul Sun Jung),전성국(Seong Gook Cheon),박기호 대한내과학회 1999 대한내과학회지 Vol.57 No.1

N/A To estimate bowel patterns in the Korean, we surveyed routine check-up subjects about their bowel habits, using self-reported questionnaire. Methods : We analyzed 2939 subjects (male 1430, female 1509; age range 25 - 65 years) who had visited health promotion center for routine check-up. Subjects were given a validated self-report questionnaire, which measured the defecation frequency; stool consistency; self-report of constipation; straining to defecate; and levels of laxative use. Results : Of the whole subjects 96.4% had defecation frequency between three per week and three per day. The prevalence of two or less bowel movements per week (4.1% compared to 0.6%), straining to defecate (20.8% compared to 13.0%) and hard stool (18.0% compared to 9.3%) was higher in women than men (p<0.01). The prevalence of self-reported constipation was higher in women than men (9.0% compared to 2.9%, p<0.01). Women were more likely to use laxatives than men (5.5% compared to 0.6%, p<0.01). Conclusions : Defecation frequency in most of routine check-up subjects is between three per week to three per day. Bowel dysfunction is a greater problem in women.