흰구름버섯(Coriolus hirsutus)에 의한 방향족 염료의 탈색

송연홍,최철민,김창진,신광수 대전대학교 이과대학 기초과학연구소 1997 自然科學 Vol.- No.-

담자균류 백색부후균의 일종인 흰구름버섯(Coriolus hirsutus)을 실험균주로 하여 수종의 난분해성 방향족염료의 분해능을 측정하였다. 사용된 4종류의 염료 중, triphenyl methane 염료인 bromophenol blue가 탈색를 95% 이상으로 가장 잘 탈색되었으며, Congo red와 Poly R-478은 이보다는 낮은 57%, 55% 가 탈색되었다. 그러나, heterocyclic 염료인 methylene blue는 본 균주에 의해 거의 탈색되지 않아TDmau, UV-visible spectrum상에서의 심색성 이동만 관찰되었다. 세포외 laccase와 peroxidase의 활성은 각 염료의 탈색율과 비례하여 나타났으며, 최대 활성 또한 최대 탈색시기에 관찰되었다. 효소의 활성 염색시 모든 연료의 탈색배지에서 공통적인 laccase와 peroxidase의 활성 띠가 관찰되었다. 이러한 결과로 볼 때, 세포의 laccase와 peroxidase가 난분해성 염료의 탈색에 중요한 역할을 할 것으로 판단된다. The white rot fungus Coriolus hirsutus decolorized several recalcitrant dyes. Four different types of dyes, including azo, triphenyl methane, heterocyclic, and polymeric dye, were treated by the mycelial preparation. Tri-phenyl methane dye, bromophenol blue lost over 95% of its color. Congo red and Poly R-478 were decolorized less than bromophenol blue, 57 and 55%, respectively. However, heterocyclic dye, methylene blue was not decolorized significantly and only red shift was observed. Extracellular laccase and peroxidase. activities were appeared maximally in high level of dye decolorization media. In electrophoretic experiments, common active bands of laccase and peroxidase were found in all dye decolorized medium. These results indicated that the culture conditions which yield high levels of laccase and peroxidase activity lead to high levels of dye decolorization, and these two enzymes might be play an important roles in dye decolorization.

고속 채널환경에 강건한 OFDM 시스템을 위한 채널추정기법

강연석,황태욱,최준철,김영수 경희-다반 ASIC 설계교육센터 2004 경희-다반 ASIC센터 논문집 Vol.5 No.-

본 논문에서는 Orhogonal Frequency Division Multiplexting(OFMB) 시스템의 성능 향상을 위해 파일럿 심볼을 이용한 향상된 채널추정 알고리즘을 제안한다 기존의 LMMSE 알고리즘을 이용한 채널 추정 방법은 파일럿 심볼만을 채널 추정에 이용함으로써 파일럿 간격이 멀어짐에 따라 성능이 현저하게 떨어지는 단점이 있다. 이런 문제를 해결하기 위해 파일럿 사이의 채널을 선 추정하고 이 추정된 값을 다시 파일럿과 함께 이용하여 채널을 추정하는 채널추정기법을 제안하였다. 제안된 추정기법은 도플러 주파수를 36Hz애서 185Hz인 페이딩 채널환경에 적용했다. 기존의 LMMSE 추정기법과 비교했을 때 특히 큰 도플러 주파수애 대해 강건한 특성을 보였다.

마이크로 압전 엑츄에이터용 Sol-Gel PZT 박막의 두께 변화에 따른 특성

장연태,박준식,김대식,박효덕,최승철 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

Pb가 10% 과잉되고 Zr : Ti = 52 : 48 조성을 갖는 PZT sol이Pt(3500A˚)/Ti(400A˚)/SiO2(3000A˚)/Si(525㎛)기판 위에 스핀 코팅법으로 반복 코팅된 후, 450℃에서 10분, 650℃에서 2분간 반복 열처리되었다.이와 같이 다양한 두께로 적층된 박막은 각 시편에 대해 최종적으로 650℃ 30분 동안 어닐링 처리되었다.제조된 PZT 박막의 두께는 4100A*에서 1.75㎛사이의 4종이었다.이어서 스퍼터링법으로 Pt전극이 PZT 막 위에 증착되었다.제조된 PZT 박막의 결정 구조 조사를 위해 XRD, 그리고 미세 구조 및 전기적 특성을 알아보기 위해 FESEM과 P-E 이력 곡선이 각각 관찰되었다.4100A˚에서 1.75㎛까지 두께 중가에 따른 장비상의 포화 이력 한계로 잔류 분극(Pr)값이 25A˚u C/㎠에서 다소 감소되었다.측정된 X선 회절 결과에서 최초 4회 코팅시 perovskite 결정 구조로 성장한 결정립은 (111)배향이 우세하였으나, 두께가 증가됨에 따라 (111)/(110)값이 감소되었으며, 이를 통해 두께 증가에 따른 (111)배향성이 다소 감소됨을 알 수 있었다.이상의 결과로부터 제조된 PZT 박막은 큰 힘과 높은 내전압 특성을 갖는 마이크로 압전 액츄에이터에 적용될 수 있을 것으로 생각되었다.

성인남자에서 등척성 근력과 등속성 근력에 관한 비교 연구

박수연,최현희,박철빈 경희대학교 체육과학연구소 1999 體育學論文集 Vol.27 No.-

The purpose of this study was to evaluate the difference of isometric and isokinetic muscular strength in collegiate athletes and general students. Sixty players(15 basketball players, 15 icehockey players, 15 baseball players, 15 soccer players) and fifteen volunteered male students were measured using versatile muscle power measuring system and Cybex 770 dynamometer. Grip strength, arm strength and leg strength were measured for isometric muscular strength. And flexion and extension of shoulder, elbow and knee at 60deg/sec(5 repetitions), 180deg/sec(5 repetitions) were measured for isokinetic muscular strength. The results were as follows : 1.Among isometric muscular strength, the highest grip strength was 47.8kg in baseball players, the highest arm strength(flexion and extension) were 18.4kg, 33.4kf in icehockey players, the highest leg flexion strength was 29.2kg in icehockey players and leg extension strength was 69.0kg in baseball players. 2.Among isokinetic muscular strength, the highest peak torque at 60deg/sec among groups were as follows : shoulder flexion in icehockey players(72.6Nm), extension in baseball players(82.4Nm) : elbow flexion and extension in icehockey players(60.1Nm, 76.7Nm) players(82.4Nm) : knee flexion in basketball players(147.0Nm) extension in icehockey players(239.3Nm). 3.The highest average power at 180deg/sec among groups were as follows : shoulder flexion and extension in baseball players(106.0watt, 121.5watt) : elbow flexion and extension in basketball players(69.1watt, 99.7watt) : knee flexion and extension In basketball players(197.7watt, 321.7watt). 4.There were significant in coefficiency correlationship(r=0.468) between isometric arm flexion strength and isokinetic peak torque of elbow. And the coefficiency correlationship between isometric arm flexion strength and isokinetic peak torque of shoulder was 0.344. The coefficiency correlationship between isometric left leg flexion and extension strength and isokinetic peak torque of knee flexion and extension were 0.460, 0.562 respectively.

청주시 도시계획 변천과 공간구조 변화에 관한 기초자료조사

권상준,최연철 淸州大學校 都市·地域開發硏究所 1996 都市·地域開發硏究 Vol.2 No.-

This survey is for the study of the transition of urban plan and spatial structure in case of Chong-Ju. The results of surveying are as follows : a. The basic data for this study should be changed into systematic. b. The relation among the basic data should be characterized to comprehensive. c. The sources of the basic data should be successive. The study suggests as follows : a. The economic situation and local fund should be independent from the central government. b. The transfortation system should be connected synthetically to regional and intre-regional networks. c. The urban central core should be decentralized into expanded business and commercial districts. d. The land use planning system should be changed into sub-divisional and more detailed districts.

여성의 피부관리실태와 관련요인

구재희,남철현,최연희,배향선,신옥순,양숙희,이명옥 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to analyze aspects of women's skin care and related factors in order to contribute to community residents's right skin care. The subjects of this study was 800 women who were 15 to 65 years old. Data were collected in Daegu City and Kyungsan City from June 21, 2002 to August 18, 2002. The results of this study can be summarized as follows. 1. According to socio-demographic characteristics of the respondents, 26.8% of them were in twenties. 50.9% of them was students at colleges or graduated from collges. 38.3% was students and 37.5% was housewives. 55.5% belonged to the middle economic class. 2. 47.9% of the respondents replied that they were in good health. 57.2% of them had fair skin, while 25.1% had dark skin. According to health condition of face skin, 61.5% was in regular condition, while 26.0% was in bad condition. 29.9% had drying face skin and 21.3% had neutral or complex character of face skin. 3. Among the reasons they had trouble with face skin, the proportion of having the rough skin was highest (25.0%). 16.6% replied that they had trouble with a lot of wrinkles and 16.3% replied that they had trouble with dark face skin. 25.4% responded that their face skin was too tight. 13.3% replied that they had trouble with scars. 4. The factors significantly influencing the experience of skin care were age, education level, residence, experience of side effect of cosmetics, experience of skin diseases on face or body, experience of trouble after receiving skin care, and experience of trouble with acne. From above results, it can be concluded that selection of proper skin care rooms is important in receiving desirable skin care and preventing side effect related to skin care. The women also must be cautious in selecting and using cosmetics and massage pack. The government, related organizations, and skin and beauty specialists must make efforts to develop education programs for healthy skin care.

정신분열병 환자의 말초 임파구에서 도파민 수용체 mRNA의 변화

곽용태,최철희,김옥준,주연호,김형섭,강성숙,구민성,선우일남 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 정신분열병은 주로 청소년기에 발병하는 정신과에서 가장 흔한 질환 중의 하나이다. 이 질환의 원인이나 병인은 아직 불확실하지만 뇌 도파민계의 기능장애가 중요한 기전으로 생각되고 있으나 부검없이 뇌 도파민계를 직접 관찰할수 없으므로 많은 혼란이 있어왔다. 이를 극복하기 위하여 최근에 발견된 말초 임파구의 도파민 수용체를 이용하여 정신분열병에 있어서 말초 임파구 도파민 수용체가 뇌 도파민계의 기능을 반영하는 말초표식인자일 가능성이 있는지를 규명한다. 방 법 : 3년 이상 항정신병 약물을 복용중인 정신분열병 환자(약물투약군) 44명, 최근 3개월 이상 항정신병 약물을 복용하지 않은 환자(약물비투약군) 43명, 정상대조군 31명을 대상으로 말초 임파구의 D3, D5 도파민 수용체를 정량적 역전사 중합효소 연쇄반응(quantitative reverse transcritpase polymerase chain reaction)을 이용하여서 정량 비교하였고, 또한 항정신병 약물을 복용하지 않은 환자들에 있어서 약물 투여 후 도파민 수용체의 변화 및 임상양상의 변화를 관찰하였다. 결 과 : 1) 말초혈액 임파구의 D3R/βA는 약물비투약군에서 정상대조군이나 약물투약군에 비하여 통계적으로 유의하게 있게 증가되어 있었다. D5R/βA의 경우 약물비투약군이 약물투약군에서만 비하여 유의하게 증가되었다. 그러나 약물투약군과 정상대조군 간에는 도파민 수용체 mRNA(D3R/βA, D5R/βA)양에 있어서 차이가 없었다. 2) 항정신병 약물을 새로 투여하는 환자에서 항정신병 약물을 투여 후 임파구 도파민 수용체의 변화를 추적 관찰한 결과 증가하는 경향을 보였다. 3) 약물비투약군을 정상 대조군과 비교하여 D3R/βA mRNA가 정상범위에 속하는 군과 높은 군으로 나누어서 임상척도와 비교 분석한 결과 임파구 도파민 수용체가 증가한 군에서 다음과 같은 임상특징을 관찰할 수 있었다. (1) 정신병리증상이(BPRS) 현저하였다. (2) 약물치료에 대해 양성 정신병리증상(pBPRS)의 호전도가 낮았다. (3) 약물치료시 추체외로 부작용이 심하였다. 결 론 : 이상의 연구결과로 말초 임파구에서 발현되는 도파민 수용체는 정신분열병의 소군 분류 및 예후 예측에 있어서 임상적 의의가 있는 것을 알 수 있었다. 따라서 말초임파구에서 발현되는 도파민 수용체는 비록 이에 상응하는 뇌의 해부학적 위치는 알 수 없지만 중추신경계의 도파민 수용체의 기능을 반영할 가능성이 높다고 생각되었다. Objectives : Schizophrenia, commonly developed in adolescence and young adulthood, is one of the most common mental diseases in psychiatry. The etiology or pathogenesis of this disease is uncertain yet, but the dysfunction of dopaminergic system in the brain has been proposed. However, there is no direct evidence of dysfunction of brain dopaminergic systems in schizophrenic patients because the direct assessment of brain dopaminergic systems is almost impossible at present. To overcome this problem, recently founded dopamine receptors and their mRNAs in peripheral lymphocytes was used. The purpose of this study was to define whether the dopamine receptors of peripheral lymphocytes can be the peripheral markers of schizophrenia or not. Methods : The total numbers of subjects are 87 schizophrenic patients. Among them 44 patients were schizophrenics who had been taking antipsychotic drugs for more than 3 years(medicated patients), 43 schizophrenics who recently are not taken antipsychotic drugs for more than 3 months(drug-free patients). For controls age and sex matched 31 healthy persons were enrolled. Sequential reverse transcription and quantitative polymerase chain reaction of the mRNA were used to investigate the expression of dopamine receptors in peripheral lymphocytes. The gene expression of dopamine receptors were compared in each groups and after starting antipsychotic medicines in drug-free patients, the clinical scales and the dopamine receptors of peripheral lymphocytes were sequentially studied before, 2 weeks after and 8 weeks after medication. Results : 1) In drug-free schizophrenics, D3 dopamine receptor mRNA expression of peripheral lymphocytes was significantly increased comparing with that of controls and drug-medicated schizophrenics and D5 dopamine receptor mRNA expression was increased comparing with only that of drug-medicated schizophrenics. There was no difference between controls and drug-medicated schizophrenics. 2) After antipsychotic medication, dopamine receptors of lymphocytes were increased tendency. 3) Drug-free patients were divided into two groups according to dopamine receptor expression in controls to evaluate the significance of increased dopamine receptor expression. The group of patients with increaseddopamine receptor expressio had following clinical characteristics. (1) More severe psychiatric symptoms (2) Poor pharmacological response of pBPRS on medicines (3) Severe extrapyramidal side effects after pharmacological treatment Conculsion : These results revealed that the molecular biologically determined dopamine receptors of peripheral lymphocytes were reactive, and increased expression of dopamine receptor in peripheral lymphocyte had clinical significance for subgrouping and prognostication. These findings suggested that dopamine receptors of peripheral lymphocyte may represent dopamine receptors of the brain, even the location cannot be determined.

일부지역 중·고등학생들의 흡연실태 조사연구

신옥순,남철현,김복용,최연희,박선희,박경옥,구재희 慶山大學校 保健福祉硏究所 2002 保健福祉硏究 Vol.7 No.-

This study was conducted to examine aspects of middle and high school students' drinking and smoking with analysis of related factors. The subjects of this study was 540 students in Kyungbuk Province. Data were collected from July, 2002 to September, 2002. The results of this study can be summarized as follows. 1. 43.6% of the boy students experienced smoking, while 12.2% of the girl students experienced it. 5.3% of the students at academy schools experienced smoking, while 44.7% of the students at vocational schools experienced it. 11.4% of the middle school students experienced smoking, while 33.9% of the high school students experienced it. 15.5% of them who lived in towns or villages experienced smoking and 38.3% of them who lived in small or medium sized cities experienced it.37.5% of the students who belonged to the lower economic class experienced smoking and 20.7% of the students who belonged to the upper economic class experienced it. 24.0% of the students who belonged to the middle economic class experienced it. It appears that the respondents showed significantly different smoking experience rates by gender, school types, grades, the number of family members, residences, and economic classes. 2. 14.5% of the respondents who lived with grandparents and parents experienced smoking and 26.5% of them who lived with parents experienced it. The smoking rate was significantly high in the groups of having one-parent, being unsatisfied with family life, making poor grades in studies, and having the father or the mother working as a salesperson. 3. 45.3% of the respondents who were unsatisfied with family life experienced smoking. The smoking rate of the respondents who were unsatisfied with it was significantly higher than that of the other groups. On the other hand, the smoking rates were not significantly different by daily life, schoolmate relation, health condition, and feeling stress. 4. According to smoking rate by frequency of drinking, 16.4% of the respondents who drank less than once a month smoked and 54.8% of them who drank more than twice a month smoked. The more frequently they drank, the higher their smoking rate was. Those who did exercise displayed significantly higher smoking rate than those who did not do exercise. Among the rates of the respondents' agonies, family disharmony was 50.5% and love problem was 39.2%. Economic condition preblem was 34.6%. It appeared that smoking was most influenced by the family disharmony. 5. The factors significantly influencing smoking experience were gender, school grade, schoolmate relation, score in studies, and exercise. From above results, it can be concluded that the students' smoking is a serious problems which can be resolved by simple approaches because it is interrelated complicatedly with gender, grade, family, school, etc. Schools, related organizations, and the government must closely work together to maximize the effectiveness of policy implementation concerning the smoking and drinking problem of the middle and high school students.

폐경 전후 여성의 신체활동 및 생활습관과 골 밀도 수치와의 관련성

배성욱,남철현,홍성철,최연희,이정옥,양숙희 대한보건협회 2002 대한보건연구 Vol.28 No.3

To evaluate the degree of bone mineral density according to physical activity, lifestyle in pre- and postmenopausal women. The subjects were 951 premenopausal and 1,167 postmenopausal women who have examined in health promotion center of Yeungnam University Hospital in Daegu city from January, 1999 to Januaty, 2001. The test for bone mineral density. The physical activity and life style were evaluated by questionaire through interview. The results were summarized as follow. 1) The prevalence rates of reduced bone mineral density and osteoporosis in premenopausal women were 23.8% and 1.6%, respectively. However, these values were increased to 46.1% and 28.1% in postmenopausal women. 2) The regular exercise was revealed to have preventive effect for osteoporosis in pre- and postmenopausal women. Among the types of exercise, the most effective exercise was bowling and moderately effective exercise was swimming on prevention of osteoporosis, however, bare hand physical exercise was not significant effect on bone mineral density. 3) The risk for reducing bone mineral density was decreased in women who have higher educational background and income in pre- and postmenopausal. The bone mineral density was highest in white color worker and lowest in blue color worker. 4) The premenopausal women who favor meat were revealed higher bone mineral density than the women who favor vegetable. The women who have drunk none or small amount of alcohol were revealed increased bone mineral density and smoking was a risk factor for osteoporosis. These results suggested that to prevent osteoporosis, the systemized program for promoting anti-osteoporotic factor have to be developed and apply from the thirties whom have maximal bone mineral density.

남자대학생들의 피부관리실태와 관련요인 조사연구

배향선,남철현,김성우,최연희,강영숙,김선혜,구재희 慶山大學校 保健福祉硏究所 2003 保健福祉硏究 Vol.8 No.-

This study was conducted to examine aspects of skin care of male students at colleges and universities of male students at colleges and universities and its related factors in order to provide informations on skin care for men. The subjects of this study was 600 men who were students at colleges and universities in Daegu City and Kyungbuk Province. Data were collected from May 1, 2002 to June 30, 2002. The results of this study can be summarized as follows. 1. According to the respondents' socio-demographic characteristics, 55.9% of them was 20 to 24 years old and 29.6% was more than 25 years old. 84.9% of them was university students, while 15.1% was college students. 25.3% belonged to the lower class, while 22.4% belonged to the upper class. 52.7% did not have a girl friend, while 47.3% has a girl friend. 41.8% lived in big cities and 48.1% lived in small and medium cities. 2. 63.0% of the respondents replied that they were in good health, while 8.8% of them were in bad health. 41.9% of them was concerned about face and body skin care, while 14.1% was not concerned about it. Among most serious skin problems, the proportion of acne was highest (44.5%). 3. Among the persons who advised the respondents when they selected cosmetics, the proportion of selecting cosmetics as their own will was highest (44.7%). 25.3% of them selected it by recommendation of female family members and 18.3% selected it by recommendation of the girl friend. In the case of selecting it as their own will, the older they were, the higher the proportion was. In the case of having the girl friend, the proportion of selecting cosmetics by recommendation of the girl friend was higher than that of selecting it by recommendation of female family members. 4. 90.4% of the respondents replied that they never visited skin care rooms, while only 9.6% of them replied that they ever visited them. In the case of visiting skin care rooms, the proportion of the upper class was higher than that of the lower class. 5. According to the frequency of visiting skin care rooms, the proportion of once a week was highest (51.0%). 29.4% of them visited them once per 6 months and 19.6% visited them once a month. 6. In the case of the reasons they did not visit the skin care rooms, the proportion of 'no interest' was highest (36.6%). 23.2% did not visit them because they thought the fee for skin care was expensive and 19.5% did not visit them because they thought the skin care room were only for women. 7. In the variables of giving advice concerning skin care, the proportion of 'their own' was highest (29.8%). The proportion of female family members was 28.2% and the proportion of the girl friend was 27.7%. In the case of the age related to having the girl friend's advice, the proportion of 'over 25 years old' was 31.9% and the proportion of '20 years old to 24 years old' was 26.4%. The proportion of 'less than 19 years old' was 23.5%. The older they were, the more they had the girl friend's advice. 8. According to the sources of getting information on skin care, the proportion of mass media (TV, Radio etc.) was highest (36.7%). 26.0% of them obtained them through the girl friend and 13.9% obtained them through female family members. Only 8.4% got them through magazines. 9. The factors influencing the experience of visiting skin care rooms were experience of side effect of foundation cosmetics, concern about skin care, expiration date of cosmetics or checking of directions of using cosmetics, donsideration of skin character when using soap, and regular exercise for health. From above results, it can be concluded that skin care and beauty specialists working in beauty academies or the department of cosmotology at colleges or universities must make efforts to change the negative recognition of male skin care through deep and comprehensive research. It is also necessary to develop systematic education course and institutionalize the qualification management system.