白鼠의 高脂血症에 蒼朴二陳湯이 미치는 影響

崔達永,金俊錡,朴元煥,金曠洛 대한동의병리학회 1997 동의생리병리학회지 Vol.11 No.2

본 연구는 한국에서 최근 발병률이 증대되고 있는 名種 循環器系 疾患의 誘發因子로서 중요시 인식되는 高脂血症에 대한 한의학적 치료방법 및 치료방제에 대한 탐색에서 시도된 논문이다. 이에 저자는 韓醫學에서 高脂血症과 개념상 유사성이 많은 心痛 胸痺 정충 水腫 眩暈 喘證 中風 等의 範疇에 속하는 병증의 치법에 다용되는 化痰祛瘀의 治方中『症因脈治』에 收載된 蒼朴二陳湯이 痰飮治療의 基本方인 二陳湯과 除濕運脾의 作用이 있는 蒼朮과 行氣의 作用이 있는 厚朴으로 構成되어 있어 高脂血症의 治療에 有效할 것으로 理論的으로 기대되어 이를 實驗的으로 立證하기 위하여 高脂肪性食餌로 高脂血症을 야기한 白鼠에 蒼朴二陳湯을 投與시켜 血淸 total-cholesterol, triglyceride, HDL-cholestrol, phospholipid, β-lipoprotein 等의 含量變化 및 total-cholesterol 含量에 대한 HDL-cholesterol 含量의 比率變化와 total-cholesterol 含量에 對한 phospholipid 含量의 比率變化 等을 觀察한 바 유의한 결과를 얻었다. 따라서 蒼朴二陳湯은 白鼠의 高脂血症病態의 改善에 有意한 效果가 있는 것으로 認定되며 高血壓, 動脈硬化 및 이로 因한 中風 等에도 臨床的 應用이 可能할 것으로 思科된다. This study was done in order to investigate the effect of Changbakleezintang on hyperlipidemia. Results: 1. The level of serum total cholesterol was decreased with the significance in the sample groups as compared with the control groups. 2. The level of serum HDL-cholesterol was increased with the significance in sample groups as compared with the control groups. 3. The level of serum phospholipid was increased with significance in Sample 1 group as compared with Control 1 group, but Sample 2 group did not show significance as compared with Control 2 group. 4. The level of serum β-lipoprotein was decreased with the significance in Control 1 group, but control 2 group did not show significance. 5. Rate of total cholesterol vs. HDL-cholesterol and total cholesterol vs. phospholipid were increased in the sample groups as compared with the control groups. It is considered that Changbakleezintang respectively had recovering effect on the Hyperlipidemia induced by cholesterol in male rats. So it can be use to prevent and treat hyperlipidemia and related deseases.

간척지 벼 담수직파재배시 토양 염농도별 적정 최아정도

최원영,이규성,김정곤 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4

간척지에서 벼 담수직파재배시 입모 향상을 위하여 토양 염 농도별 적정 최아 정도를 구명하기 위하여 시험한 결과는 다음과 같다. 가. 입모수는 저염 토양은 건종자 파종에서만 적었고 그 외 처리에서는 비슷하였으며, 중염 토양은 반대로 최아 0㎜와 건종자 파종에서 많았다. 나. 출수기는 저염 토양에서는 최아 4㎜가 8월 18일인데 비하여 2 ㎜와, 0 ㎜에서는 같았으나 소독후 건조종자 파종에서는 1일이 늦었으며. 중염 토양에서는 최아 4㎜에 비해 2㎜는 같았고 건조종자 파송에서는 1일이 늦었으나 0㎜ 파송에서는 오히려 1일이 빨랐다. 다. 저염 토양에서는 ㎡당립수가 최아 4>2>0㎜>건종자 순으로 많아 쌀 수량도 최아2~4 ㎜에서 많았으며, 중염 토양에서는 도복에 강하고 등숙비율이 높은 최아 0㎜와 건 조종자 파송에서 쌀 수량이 많았다. 따라서 저염 토양에서는 최아 2~4㎜가 적당하고, 중염 토양에서는 최아 0㎜ 또는 소독 후 건조종자 파종이 적당할 것으로 판단된다. This study was conducted to examine an appropriate pregermination treatment of rice seeds for wet seeding on the wet surface of a reclaimed saline soil. It was conducted at the Gyehwado Substation of the Honam Agricultural Research Institute in 2002~2003. Two soil saline solutions (0~0.1% NaCl and 0.3~0.4% NaCl) and four pregermination seed treatments (nonsoaking, water absorption only, 2 ㎜ pregerminated, and 4 ㎜ pregerminated) were used. The experiment was carried out in a split plot design with three replications. At low soil salinity (0~0.1% NaCl), the number of spikelets and the percentage of ripened grain increased with a longer sprouting length of rice seed compared with that of nonsoaking (dry seeds) and water absorption only. Pregerminated seed treatments showed significant high rice yield performance in low saline conditions indicating pregerminated treatments are necessary for good seedling establishment and growth of rice. However, rice seeds treated with nonsoaking and water absorption only had higher yield performance in a medium soil salinity level (0.3~0.4%) than the pregerminated ones. This result indicated that pregerminated seeds seeded under a medium soil salinity level could have damaged shoot tips and roots, thus the growth would be retarded and soaking seeds float because of high soil salinity.

간척지 중염답에서 유수형성기 염처리에 따른 벼 생육 및 수량 변화

최원영,이규성,고종철,김상수,김태수 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.3

본 연구는 새계화벼를 공시하여 간척지 중염답(0.3~0.4%)에서 관개수 염농도에 따른 생육 및 수량성을 검토하고자 유수형성기에 5일간 염수를 처리하여 시험한 결과를 요약하면 다음과 같다. 1. 관개수 염분농도가 높을수록 벼 출수는 1~2일 지연되었고, 출수기 지상부건물중은 가벼워졌다. 2. 간장과 수장은 관개수 염분농도가 높을수록 짧아졌다. 3. 관개수 염분농도가 높을수록 수당 립수가 적어 ㎡당 립수가 적었으며, 등숙비율이 낮고 현미 천립중이 가벼워, 쌀 수량은 민물 관개(무처리)의 330㎏/10a에 비해 관개수 염분농도 0.1%는 94%, 0.3%는 85%, 0.5%는 76%, 0.7%는 71%의 수량을 얻었다. 4. 관개수 염분농도가 높을수록 완전립 비율은 낮아졌다. 따라서 간척지에서 중염도 토양(0.3~0.4%)에서 벼를 재배하여 유수형성기에 한발이 닥쳐 저류지 등 염분 농도 0.7%의 물로 5일간 담수하여도 쌀 수량은 29% 정도 감수되고 쌀의 품위도 저하되지만 어느 정도 수량은 얻을 수 있을 것으로 생각된다. This experiment was conducted at the Kyehwado Substation of the National Honam Agricultural Experiment Station(NHAES) RDA, Korea. The experimental field contained 0.38% NaCl in soil solution. The experiment was involved five treatments (control, 0.1, 0.3, 0.5, 0.7%) in a randomized complete block design with three replicates, saline solution was applied only one time at panicle formation stage for 5 days. Saegyehwabyeo, a japonica rice variety was used in this experiment. In yield components, Spikelets number per ㎡ decreased with increasing salinity level, particularly in the 0.7% of saline solution water. This factor affected the most yield reduction among the components. The percentage of ripened grain was inclined to decrease with increasing salinity level. 1,000 grain weight decreased with increasing salinity level but it was lest affected by salinity among yield components. The reduction of milled rice yield decreased significantly with increased saline water level, in detail 6% of yield reduction at the 0.1% saline solution, 15% at the 0.3%, 24% at the 0.5%, and 29% at the 0.7% saline solution level compared with control respectively. Results indicate that the gaining of rice yield could be reliable performance in terms of economical benefit for rice production even though high reduction of yield occurred at high salinity levels on a reclaimed saline soil in Korea.

전방 도달법과 수장부 T자형 금속판 고정을 통한 원위 요골 골절의 치료

최우성,김원유,최동원,신윤학,김진영 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목적 : 원위 요골 골절에 대해 전방 도달법을 이용한 관혈적 정복 및 수장부 T자형 금속판 내고정술의 방사선학적 및 임상적 결과를 분석하여 문헌 고찰과 함께 보고하고자 한다. 대상 및 방법 : 도수 정복이 되지 않았거나, 심한 분쇄 골절로 인해 도수 정복 상태가 유지되지 못했거나, 부적절한 관절면의 정복 등의 이유로 원위 전완부 전방 도달법을 이용한 관혈적 정복 및 수장부 T자형 금속판을 이용한 내고정술을 시행 후 최소 1년 이상 추시 관찰이 가능하였던 19예를 대상으로, 수술 전 후의 방사선학적인 평가와 최종 추시시의 기능적 평가를 Green과 O'Brein의 방법을 이용하여 평가하였다. 결과 : 수술 직후 모든 예에서 관절면의 해부학적 정복을 얻을 수 있었다. 방사선학적 결과에서 요골 관절면의 요골 길이는 수술 전 평균 8.8 ㎜ (±4.8 ㎜)에서 수술 후11 ㎜ (±3 ㎜)로, 요골 경사각은 평균 15˚ (±5.7˚)에서 20˚ (±5˚)로, 전방 경사는 평균 -11˚ (±13˚)에서 7˚ (±4˚)로, 척골 양성 변이는 평균 4 ㎜ (±3 ㎜)에서 0 ㎜ (±1 ㎜)로 향상되었으며, 기능적 결과에 있어서는 우수 9예, 양호 7예, 보통 2예, 불량 1예 이었다. 추시 중 초기 수상이 심하였던 1 예에서는 정복의 소실과 함께 장 무지 굴건의 파열이 초래하였다. 결론 : 원위 요골 골절의 수술적 치료에서 일부 제한된 범위에서만 적응증이 되었던 수장부 금속판 내고정술로 방사선학적 측면과 기능적인 측면에서도 만족할 만한 결과를 얻었으며, 초기 분쇄 골절이 심할 경우에는 정복의 소실을 예방하기 위하여 외고정기를 부수적으로 장착하는 것이 좋을 것으로 생각된다. Purpose : To analyze the radiologic and clinical results of open reduction and volar plating through anterior approach for distal radius fracture. Materials and Methods : We retrospectively analysed that 19 distal radius fracture, which would not be reduced by closed reduction or too comminuted to maintain reduction or articular surface incongruency, were treated by open reduction and volar plating through anterior approach. The results were evaluated by preoperative and immediate postoperative radiographics and clinical results were analysed using Green and O'Brien scoring system at final follow up. Results : All cases achieved anatomical articular surface reduction postoperatively. In terms of radiologic analysis, mean radial length (8.8 ㎜±4.8 ㎜ vs. 11 ㎜±3 ㎜), radial inclination (15˚±5.7˚ vs. 20˚±5˚), volar tilt (-11˚±13˚ vs. 7˚±4˚) and ulnar plus variant (4 ㎜±3 ㎜ vs. 0 ㎜±1 ㎜) were improved. The clinical evaluation revealed 9 excellent cases, 7 good cases, 2 fair cases and I poor case. The reduction loss and flexor pollicis longus rupture was occurred in one patient, who had severely displaced comminute fracture in initial injury. Conclusion : Using volar plating, authors gain good radiologic and clinical results. But, additional external fixation is recommended to prevent further collapse in severly comminuted fractures.

조직구성 수성망상증 2예

최연수,박일,죄희충,김원식,양태영,허경,안기완,정춘해 조선대학교 1993 The Medical Journal of Chosun University Vol.18 No.2

Histiocytic medullary reticulosis (HMR) is a malignant noeplastic process, with tumor cells belonging to the histiomonocytic line, and originally described by Scott and Robb-Smith in 1939 characterized by its acute onset, progression to death within a few months and its clinical features are fever, lymphadenopathy, hepatosplenomegaly, jaundice, and purpura common laboratory findings are characterized by severe anemia, leukopenia, thrombocytopenia and histologically by systemic progressive invasion of morphologically atypical histiocytes or of their precursor. 61 and 37-year-old males were admitted with camplaints of high fever and chilling sensation and were treated by cyclophosphamide, vincristine, prednison and antiobiotics, but patients all died 17 and 14 days after admission due to probably sepsis and respiratory failure.

식도를 포함한 전위장관을 침범한 전이성 악성 흑색종 1예

최정영,김준기,신성하,고영춘,조상욱,서강석,강명원,임연근,여향순,김경수 全南大醫大 2001 전남의대학술지 Vol.37 No.1

벼 밭재배에 따른 수량 및 미질

최원영,최민규,김상수,이규성,김태수,이재길 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4

벼 밭재배시 논벼 품종들의 적응성을 검토하기 위하여 마늘 간작으로 벼를 건답점파하여 재배한 결과를 요약하면 다음과 같다. 1. 입모율은 밭벼에 비해 논벼 품종이 낮았는데 그 순서는 상남밭벼〉동진찰벼〉신선찰벼〉진부찰벼 순이었다. 2. 출수기는 상남밭벼에 비해 진부찰벼는 3일 빨랐고 신선찰벼는 9일, 동진찰벼는 12일이 늦었다. 3. ㎡당 수수와 등숙비율은 밭벼에 비해 논벼품종들이 높았다. 4. 쌀수량은 상남밭벼에 비해 신선찰벼는 12%가 많았고 동진찰벼는 같았으며, 진부찰벼는 18%가 적었다. 5. 완전립비율은 진부찰벼에서 높았고 그 외는 비슷하였으며, 식미지수는 상남밭벼에 비해 동진찰벼는 높았으나 진주찰벼와 신선찰벼는 낮았다. To identify the rice varieties adaptable for upland cultivation, a series of experiments was carried out at the field(Chonnam series) of the Muan. Cheonnam province during 1999 - 2001. Four varieties, Jinbuchalbyeo(early-maturing variety), Sinseonchalbyeo (medium-maturing variety), Dongjinchalbyeo(medium-late maturing variety), and Sangnambatbyeo as a standard variety for upland were used in this experiment. Seedling establishment of the varieties was the highest in Sangnambatbyeo and followed by Dongjinchalbyeo under upland condition. Heading date in general delayed ranges from 9 to 12 days, while early-maturing variety, Jinbuchalbyeo was faster for 3 days compared with Sangnambatbyeo. Number of panicle per square meter was similar in both lowland and upland rice but percentage of ripened grain was high in lowland rice. Milled rice yield was high as of 12% in Sinseonchalbyeo compared with Sangnambatbyeo. Head rice ratio showed also the highest in Sinseonchalbyeo. The results indicate that Sinseonchalbyeo as glutinous rice variety could adapt well in this upland condition, and have good milling recovery as head rice as well as yield advantage.

血栓症과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯이 미치는 影響

박원환,최달영,文濬典 東國大學校韓醫學硏究所 1993 東國韓醫學硏究所論文集 Vol.2 No.1

To see both Shunqidaotantang(dissipate phlegm and promote vital energy circulation) and Huayutang(blood circulation and disperse blood stasis) influencing on thrombosis, contusion-hyperemia, and hyperlipidemia, at first we measured the density of FDP, the quantity of fibrino-gen, prothrombin time, and the number of platelet of rat taken thrombosis by endotoxin. Secondly we measured the increase-rate of "paw swelling", the number of platelet, the quantity of fibrino-gen, and pothrombin time of rat taken contusion-hypermia. And then we measured the quantity of total cholesterol in serum and of H.D.L-cholesterol and of triglyceride and of phospholipid and of β-lipoprotein, its weight, and the variation of the quantity of electrolyte of rat taken hyperlipidemia by the oral-injection of cholesterol. As a result, we can conclude as follows: 1. Out of the test of thrombosis, we can recognize not only the noticeable increae of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and the density FDP in case of Shunqid?otant?ng-injected rat and Huay?t?ng-injected rat. 2. Out of the test of contusion-hypermia, we can recognize not only the noticeable increase of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and "increase-rate of paw swelling" in case of Shunqid?otant?ng-injected rat and Huay?t?ng-injected rat. 3. Out of the test of hyperlipidemia, at first we can recognize that test rat's weight increased as close as that of normal rat. And we can recognize the noticeable decrease of the triglyceride and phospholipid and β-lipoprotein. " Also, in case of the variation of electrolyte we can recognize the decrease of calcium and potassium in Shunqidaotantang-injected rat, and of sodium and magnesium in Huayutang-injected rat. Thus, as the above-mentioned, in covering thrombosis, contusion-hypermia, and hyperlipidemia, the effect of Shunqiduotantang and Huay?t?ng can be recognized. Granting that Huayutang reveals its effectiveness in thrombosis and contusion-hyperemia, and Shunqid?otant?ng in hyperlipidemia, it can be inferred that contusion-hyperemia is like "model of blood stasis form" as thrombosis and hyperlipidemia "phlegm-retention diseases form ", and both phlegm-retention and blood stasis have correlation each other.

血栓症과 打撲性 充血 및 高脂血症에 順氣導痰湯 및 化瘀湯 미치는 影響

朴元煥,崔達永,文濬典 동국대학교 한의학연구소 1993 東國韓醫學硏究所論文集 Vol.2 No.1

To see both Shunqidaotantang(dissipate phlegm and promote vital energy circulation) and Huayutang(blood circulation and disperse blood stasis) influencing on thrombosis, contusion-hyperemia, and hyperlipidemia, at first we measured the density of FDP, the quantity of fibrinogen, prothrombin time, and the number of platelet of rat taken thrombosis by endotoxin. Secondly we measured the increase-rate of "paw swelling", the number of platelet, the quantity of fibrinogen, and prothrombin time of rat taken contusion-hyperemia. And then we measured the quantity of total cholesterol in serum and of H.D.L-cholesterol and of triglyceride and of phospholipid arid of P-lipoprotein, its weight, and the variation of the quantity of electrolyte of rat taken hyperlipidemia by the oral-injection of choleserol. As a result, we can conclude as follows : 1. Out of the test of thrombosis, we can recognize not only the noticeable increae of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrornbin tirne and the density of FDP in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 2. Out of the test of contusion-hyperemia, we can recognize not only the noticeable increase of the number of platelet and the quantity of fibrinogen, but also the noticeable decrease of prothrombin time and "increase-rate of paw swelling" in case of Shunqidaotantang-injected rat and Huayutang-injected rat. 3. Out of the test of hyperlipidemia, at first we can recognize that test rat s weight increased as close as that of normal rat. And we can recognize the noticeable decrease of the triglyceride and phospholipid and P-lipoprotein. Also, in case of the variation of electrolyte we can recognize the decrease of calcium and potassium in Shunqidaotantang-injected rat, and of sodium and magnesium in Huayutang-injected rat. Thus, as the above-mentioned, in covering thrombosis, contusion-hypermia, and hyperlipidemia, the effect of Shunqidaotantang and Huayutang can be recognized. Granting that Huayutang reveals its effectiveness in thrombosis and contusion-hyperemia, and Shunqidaotantang in hyperlipidemia, it can be inferred that contusion-hyperemia is like model of blood stasis form as thrombosis and hyperlipidemia "phlegm-retention diseases form", and both phlegm-retention and blood stasis have correlation each other.

평야지재배 조생종 벼의 이화학적 및 식미특성 분석

정진일,김기영,최윤희,최원영,고종철,오명규,홍하철,이승엽,이명철 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4

평야지재배 적응 조생종 벼 품종의 선발 및 품종 육성의 기초 자료로 활용코자 극조생종(1품종)과 조생종(10품종) 및 준조생(3품종)등 총 14품종을 산간지(운봉)와 평야지(익산)에 지역별 표준재배법으로 공시한 결과, 1. 극조생종 및 조생종들은 감온성이 커 산간지에서 출수가 빠르나, 준조생종에 속하는 상미벼, 영덕34호, 히또메보레 등은 감광성이 감온성보다 커, 평야지재배에서 4일정도 빨리 출수하였다. 2. 수량성은 대부분의 품종들이 산간지재배에 비해 평야지 재배에서 높았고 대체로 출수가 빠른 품종일수록 지역간의 수량차가 크게 나타났으며, 출수가 다소 늦은 준조생종들은 산간지와 평야지의 재배에서 수량차가 크지 않아 산간지 뿐만 아니라 평야지에서도 적응성이 높았다. 3. 단백질함량은 숙기가 다소 늦은 품종일수록 낮은 경향을 보였고 산간지보다는 평야지에서 낮았으며, 품종간에는 오대벼, 운봉30호, 영덕34호, 신석조생, 상미벼 등이 함유량이 낮았다. 4. 식미치는 산간지재배가 평야지에 비해 보다 높게 나타났고, 출수가 늦을수록 높았으며, 지역간 차가 크게 나타난 품종은 극조생종인 키라라397이었고, 출수가 늦은 상미벼와 히또메보레는 차가 적었다. 5. 산온도와 수량과의 상관은 산간지에서만 영향이 있을 뿐 평야에서는 영향이 적고 일사량과 일조시수가 수량에 보다 상관성이 높았으며, 식미치는 적산온도와는 부의상관, 생육 일수와는 정상관을 보였다. This experiment was carried out to clarify the difference of rice yield and the quality of rice in southern plan area and in alpine area. Yield and quality of fourteen early varieties were investigated under the different transplanting dates and planting densities in southern plan area(Iksan) and in alpine area(Unbong). In the alpine area, extremely early variety and early varieties headed early compared to the plain area, but medium early varieties headed about 4 days late unlike the alpine area. The yield difference of most early varieties including Kilara 397 of extremely early flowering variety were greater in plain area than in alpine. The different of yield between plain and alpine area was less in varieties with Sinseogjosaeng, Odaebyeo, Akidagomachi, and Yeungdeuk34. The rate of protein was lower in plain area than alpine and more lately flowering than early, but palatability of milled rice was higher at the alpine area and more lately flowering varieties. Correlation coefficients between yield and meterological data during maturity, yield shower the significant correlation with integrated solar radiation and sunshine hours at cultured in southern plan area, but it showed only cumulative temperature in alpine area. Palatability of miller rice was positive correlation at growth duration but negative correlation at cumulative temperature.