라세믹 에피네프린 흡입치료로 호전된 성대문연축 1례

최서희,박경배,박준수,김영창 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Laryngospasm can occur during induction of anesthesia, especially with inhalational anesthetics, up to 2% of all anesthetic inductions in children younger than age 9yr and is half as common in older patients. When laryngospasm occurs, it can be relieved during induction of anesthesia by deepening the anesthetic, muscle relaxation with succinylcholine, or constant positive airway pressure. A prior history of stridor increases the likelihood of postoperative complications. Stridor may be severe enough post laryngoscopy to require intubation. In this case, racemic epinephrine aerosols would be a effective therapy. We experienced a case of laryngospasm which is treated by racemic epinephrine aerosol. The patient's mother had smoking history, laryngomalacia was revealed on larnygoscopy. By the way, unfortunally, laryngospasm was developed on the diagnostic laryngoscopy. It was reluctant to treatments of epinephrine intramuscular injection or dexamethasone. We decided to use the racemic epinephrine aerosols including beta-agonist or budesonide alternatively, and his respiratory distress was resolved.

섬진강 수계의 부착조류에 대한 생태학적 연구

최민규,김백호,최환석,이경보,이덕배,정연태 원광대학교 환경과학연구소 1997 環境科學硏究誌 Vol.6 No.1

모유영양아와 인공영양아의 피하지방 및 상완위의 성장발육 상태 : 영아의 피하지방 및 상완위 발육상태

최경숙,최혜미,구재옥,임경숙,김주혜,김숙배 동아시아식생활학회 1997 동아시아식생활학회지 Vol.7 No.1

One- to three- month-old infants (n=232) were compared their upper arm cumference and skinfold thickness(triceps, subscapular) by feeding methods in cross-sectional study. There were two groups : breast-fed(BF) and formula-fed groups(FF). As reported previously^(7)), weight, length, head and chest circumferences of these infants were good, and overall growth status was not significantly different by feeding methods, but weight, weight velocity and chest circumference of formula-fed infants were higher than breast-feds at 3 month, significantly. Here, the triceps skinfold thickness of infants at 1, 2, and 3 postpartum months were 7.4, 9.5 and 10.5 ㎜, respectively. The triceps skinfold thickness of breast-fed infants were higher than formula-feds at 1 and 2 postpartum month, but at 3 month, that of formula-fed infants was greater than breast-fed infants, insignificantly. The subscapular skinfold thickness of infants were 6.4, 9.2 and 10.6 ㎜ at 1 to 3 postpartum months, respectively. The upper arm circumference of infants were 11.7, 13.4, 14.3㎝, and the arm muscle diameter were 34.5, 39.3 and 41.7㎝ at one to three postpartum months, respectively. The upper arm circumference of male infants was higher than females at 2, 3 postpartum months. Overall, there were no significant differences between feeding methods in triceps and subscapular skinfold thickness, upper arm circumference and arm muscle diameter. But 3-month-old formula-fed male infants showed bigger significantly in arm circumference than the breast-feds. From this survey, long-term survey on growth and body composition of large scales might be necessary to determine the effect of feeding methods of infants after 3 months and to set proper body composition standard for infant.

외상후 발작의 위험인자에 대한 조사

이재학,배학근,윤석만,도재원,이경석,윤일규,최순관,변박장 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Risk Factors for Posttraumatic Seizure The authors evaluate the risk factors for posttraumatic seizures. this prospective study was performed in a series of 470 head injured patient from January 1996 to Decomber 1998. The patients who were dead within 1 week of injury or children from 3 years old and under were excluded. There were 358 male and 112 female with a mean age of 35.2±22.8 years (range, 4-88 years). The results were as follows : 1). Of the 470 patients, pasttraumatic seizure occurred in 48 patients(10.2%): early seizure in 28(6%) and late seizure in 20 patients(4.2%). 2). The clinical risk factors for posttraumatic seizure were poor consciousness at admission, presence of brainstem herniation signs, poor GCS score, and posttraumatic amnesia more than 24 hours after trauma(p<0.001). 3). The radiological risk factors for posttraumatic seizure were subdural hematoma(p<0.001), intracerebral hematoma (p<0.02), mutiple intracranial CT lesions(p<0.001), or delayed lesions on follow-up CT scans(p<0.001). the incidence of seizure increased according to the severity of diffuse brain lesion(p<0.001), and the seizure rate in mass lesion was higher than that in diffuse lesion(p<0.001). 5). Hypoxia and coagulopathy had a statistically significant influence on posttraumatic seizure(p<0.05). Hypoxia had a infuence on occurrence of late seizure(p<0.05). 6). The incidence of posttraumatic seizure signiticantly increased in surgical group compared with coservative group(p<0.001) and significantly increased in patient who underwent decompressive craniectomy compared with those who underwent craniotomy(p<0.001) 7). Preventive administration of antiepileptic drugs decreased the incidence of early seizure, but did not affect on the reduction of late seizure. 8). Multivariate logistic regression analysis showed the subdural hematoma, GCS score, delayed lesion, and intracerebral hematoma in order of importance for seizure risk. in conclusion, the risk factors affecting on the occurrence of seizure were clinical status at admission, CT lesions, and severity of diffuse brain inJury. Considering that hypoxia affected on the late seizure, it is necessary to detect and treat it immediately after trauma. In addition, the patients who underwent decompressive craniectomy should be carefully followed to evaluate the risk of late seizure. Even though preventive administration of antiepileptic drugs had a tendency to decrease the incidence of early seizure, it is unclear whether administration of antiepileptic drugs can reduce the incidence of posttraumatic seizures. Prospective study will be needed in the selected patients.

새고막을 이용한 분말조미료 가공

오영열,강동수,김해섭,김경은,최옥수,배태진 여수대학교 산업기술지역개발연구소 2000 産業基術硏究所 論文集 Vol.9 No.-

Conditions for processing dried condiments with bloody clam were investigated. The enzymatic hydrolysis for 1 hour was more profitable than hydrothermal extraction to develop flavoring matters from bloody clam. As a result of omission tests, nucleotides were predominated in the taste compounds of bloody clam hydrolysates rather than free amino acids, and the contribution of nucleotides and free amino acids to the taste of bloody clam hydrolysates was remarkable. The major flavoring components of bloody clam hydrolysates were free amino acids and oligopeptides below 500 dalton. When bloody clam hydrolysates were separated with membrane(molecular weight cutoff 500 dalton) for recovering flavor, recovering yields of amino type nitrogen were 92.4%. Proximate compositions of dried condiments prepared with protease hydrolyzed bloody clam were moisture content 3.6%, total nitrogen were 71.2% amino nitrogen were 47.8%. And drying yield, solubility and absorption rates at Aw 0.88 were 21.4%. 86.3% and 6.6%, respectively.

자발성 뇌지주막하 출혈 환자에서 최초 뇌실 크기의 임상적 의의

신일영,윤일규,윤석만,도재원,이경석,배학근,최순관,변박장 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

The purpose of this study is to invesetigate the clinical significance of initial enlargement of ventricle in the patients who had aneurysmal SAH. Of the total 821 patients with aneursmal SAH who were registerd in SAH data bank system between 1989-1999, 307 patients who had been already measured in the size of ventricle at the time of admission, were studied retrospectively. The size of ventricle was calculated by bifrontal index. Normal size of ventricle was defined as 30% or less, mild enlargement was defined as 31 to 39%, and moderate enlargement of vertricle was defined as more than 39% in bifrontal index. The sizes of ventricle using bifrontal index were analysed according to the age, sex, blood pressure, consciousness at admission, medical history of hypertension, location of ruptured aneurysm, Fisher's grade on CT(computerized tomography) scan at the time of admission, cerebral vasospasm, intraventricular hemorrhage (IVH), performance of external ventricular drainage (EVD), and prognosis at discherge. Chi-square test and ANONA were used in the statistical evaluation. The results were as follows : 1) Of the 307 patients, 235(76.5%) had a mild to moderate enlargement of ventricle at the time of admission (more than 30% in bifrontal index). 2) The size of ventricle was enlarged according to the increase of age (p<0.05). 3) In the patients who had ruptured aneurysm on anterior cerebral artery, the size of ventricle significantly increased and showed a higher incidence in mild enlargement compared with moderate enlargement of ventricle (p<0.05). 4) The size of ventricle increased in th patients who had IVH and the EVD was more frequently performed in th patients who had the enlarged ventricle associated with IVH (p<0.05). 5) In the patients who had high Fisher's grade, the size of ventricle had a tendency to increase, but there was no statistical significance. 6) In the patients who had poor prognosis, the size of ventricle had a tendency to increase, but there was no statistical significance. Conclusively, the initial size of ventricle was enlarged in th aged patients, ruptured aneurysm on anterior communicating artery, high FIsher's grade, patients associated with IVH. Considering those factors, prediction for the enlargement of ventricle size may help to treat the patients suffering aneurysmal SAH.

일차의료에 내원한 성인에서 대사증후군의 유병률 및 관련 요인에 대한 연구

박혜순,신호철,김병성,이가영,최환석,신정아,남윤덕,배상필,천경수 대한비만학회 2003 The Korean journal of obesity Vol.12 No.2

연구배경: 심혈관 질환은 치근 국내에서 그 발생률과 유병률이 급증하여 점점 중요한 국민 건강 문제로 대두되고 있다. 2001년 NCEP ATP Ⅲ에서는 대사증후군에 대해 임상적으로 손쉽게 적용할 수 있는 기준을 제시하면서 심혈관 질환의 주 관리 차상으로 취급하였다. 본 연구에서는 일차의료에서 대사증후군의 유병률을 파악하고, 대사증후군과 관련된 요인을 규명하여 한국인에게 적절한 대사증후군 관리전략을 개발하고자 하였다. 방법: 전국 9개 병·의원 가정의학과에 내원한 20세 이상 80세 미만 성인에서 건강 문제와 무관하게 연속적 조사를 시행하여 총2,134명이 연구에 참여하였다. 대사증후군에 대해서 복부비만은 남자 ≥ 90cm, 여자 ≥ 80 cm으로 하였고 다른 위험인자들은 NCEP ATP Ⅲ의 기준에 따라 정의하였다. 신체 계측, 심혈관 위험인자를 측정하고 생활 습관을 조사하여 대사증후군의 유병률과 관련 요인을 파악하였다. 결과: 일차의료에 내원한 성인에서 대사증루군의 유병률은 남자에서 31.3%, 여자에서 29.5%로 나타났으며, 연령이 증가할수록, 비만도가 증가할수록 대사증후군의 유병률이 높아지는 경향을 나타냈다. 남자에서는 연령, 고소득, 비만, 과다 음주. 과다 흡연이 대사증후군의 관련 요인으로, 여자에서는 연령, 무직, 비만, 심혈관 질환의 가족력, 중등도의 스트레스가 관련 요인으로 나타났다. 결론: 대사증후군은 일차의료에 내원하는 성인 중 비교적 흔하게 나타나는 건강 문제로 약 30%의 유병률을 보였다. 일차의료에서 무증상 성인에게도 허리둘레 측정, 심혈관 위험인자 검사 등 대사증루군의선별검사에 의한 조기 발견과 예방적 차원의 관리가 필요하다고 하겠다 Backgroud: Cardiovascular disease is becoming an important national health issue since its recent increase in incidence and mortality. Despite the significant increase in mortality rate of cardio-vascular disease in Korea, there have been no specific studies concerning metabolic syndrome. The aim of this study was to assess the prevalence of metabolic syndrome and to evaluate the associated factors among adults who visited the primary care. Methods: A total of 2,134 subjects aged 20-79y were recruited from nine primary care clinic. The metabolic syndrome was defined by NCEP ATPⅢ criteria, however, abdominal obesity was assessed by ≥90cm in men and ≥80 cm in women. Anthro-pometric variables and cardiovascular risk factors were measured, and lifestyle factors were assessed through a questionnaire. Results: The prevalence of metabolic syndrome was 31.3% and 29.5% in men and women, respectively. The risk factors associated with metabolic syndrome, in common for both genders, were found to be age, and obesity. Excessive alcohol intake, and heavy smoking were also found to be risk factors of metabolic syndrome in men whereas moderate stress and family history of cardiovascular disease served as risk factors in women. For both genders, greater increase in body weight correlated with higher risk of metabolic syndrome. Conclusion: The prevalence of metabolic syndrome is presumed to be high considering the fact that it is commonly encountered in primary care, therefore a screening program for prevention and management of metabolic syndrome is required.

적립계 장수형 붉은곰팡이병 중도저항성 제면용 밀(Triticum aestivum L.) ‘태중’

김경민(Kyeong-Min Kim),김경훈(Kyeong-Hoon Kim),정영근(Young-Keun Cheong),최창현(Chang-Hyun Choi),김양길(Yang-Kil Kim),박종호(Jong-Ho Park),김경호(Kyong-Ho Kim),장지선(Jiseon Jang),최진경(Jin Kyung Choi),배정숙(Jeong-Suk Bae),민병규(B 한국육종학회 2019 한국육종학회지 Vol.51 No.4

A winter wheat (Triticum aestivum L.) cultivar, ‘Taejoong’, was developed by the National Institute of Crop Science, Rural Development Administration in 2016. It was derived from a cross between ‘Xian83(104).11’ and ‘Keumkang’ in 2005. It was generated through the bulk and pedigree methods for six years, and then designated as ‘Iksan370’ after a two-year advanced yield trial test. This variety was designated the name ‘Taejoong’ after a regional yield trial test in eight locations throughout Korea for three years from 2014 to 2016. Its heading date was April 27 in upland and paddy filed conditions, and its maturity date was June 7 in uplands and June 4 in paddy fields, which were late compared to that of ‘Keumkang’. ‘Taejoong’ had 417 spikes per m2, which was 300 less than that of ‘Keumkang’. However, the spike length was 13.4 cm and the number of kernel per one spike was 48, which was 5.8 cm longer and 19 higher than those of ‘Keumkang’, respectively. ‘Taejoong’ showed strong resistance to lodging and moderate resistance to Fusarium head blight, but was susceptible to powdery mildew. ‘Taejoong’ flour yield (71.8%) and flour lightness (91.90) were similar to those of ‘Keumkang’, but its protein content (11.1%), gluten content (8.8%), and sodium dodecyl sulfate-sedimentation volume (34.2 ml) were lower. These result showed that the flour dough strength of ‘Taejoong’ was weaker than that of ‘Keumkang’. The high-molecular-weight gluten subunit compositions of ‘Taejoong’ were Glu-A1 (N), Glu-B1 (7+9), and Glu-D1 (2+12). The granule-bound starch synthase compositions were Wx-A1, Wx-B1, and Wx-D1. The puroindoline compositions were Pina-D1 (a type) and Pinb-D1 (b type). The average grain yield of ‘Taejoong’ in a regional yield trial was 5.3 ton/ha in uplands and 4.6 ton/ha in paddy fields, which were 21% and 13% higher than that of the reference cultivar, ‘Keumkang’, respectively. (Registration No. 7378).

[P9-11] A Newly Synthesized, Potent Tyrosinase Inhibitor

Sung Jin Bae,Eun Kyeong Lee,Ji Min Kim,Jehun Choi,Young Mi Ha,Eunkyue Choi,Yu Kyeong Han,Hun Jung Kim,Hyoung-Sam Heo,Suhee Song,Hyojin Lee,Hongsuk Suh,Hae Young Chung 한국식품영양과학회 2009 한국식품영양과학회 학술대회발표집 Vol.2009 No.11

충남지역 일부 남자 고등학생의 아침결식에 따른 식태도, 식행동 및 영양지식

최원경(Won-Kyeong Choi),배윤정(Yun-Jung Bae),김은진(Eun-Jin Kim),김명희(Myung-Hee Kim),최미경(Mi-Kyeong Choi) 동아시아식생활학회 2011 동아시아식생활학회지 Vol.21 No.6