방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암연구소 2003 암연구소 업적집 Vol.3 No.-

Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

진행암 환자에서 Cisplatin 병용화학요법 시 Ondansetron의 오심 구토 조절 효과

조문준,윤환중,전의건,길준영,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

Ondansetron is a novel agent that selectively binds to the 5-hydroxytryptamine_3 receptor, and has been reported to have a prominent effect in the prevention of anti-neoplastic agent induced nausea and vomiting. Twenty solid tumor patients who were scheduled to receive cisplatin containing combination chemotherapy participated in a prospectively open-labeled study to evaluate the antiernetic efficacy and safety of ondansetron. The male to female ratio was 11 : 9 and median age was 49(16-70). The sites of primary neoplasms and number of patients were as following : head and neck 4, metastatic carcinoma of unknown primary site 3, stomach 3, osteosarcoma 2, ovary 2, esophagus 1, melanoma 1, penile 1, bladder 1, cervix 1, and extragonadal germ cell 1. Ondansetron was given as an 8mg loading dose IV before chemotherapy followed by 8mg IV every 8 hours until 24 hours after chemotherapy completion. Complete or major control(0 to 2 emetic episodes) of emesis was achieved in 17 of 20 patients(85%;complete 50%, major 35%) receiving ondansetron during the first 24hrs of chemotherapy. During the period of day 2 through clay 5 of chemotherapy, 14 of 20(75%) patients had complete or major control of emesis(complete 35%, major 35%). No severe side reactions were recorded in ondansetron treated patients, while mild to moderate headache was noted in 20% of patients. These results show that ondansetron is effective in the control of cisplatin induced nausea and emesis, and can be administered safely with minimal side effects.

액체막법에 의한 중금속이온의 분리 및 회수

曺文換,丁學鎭,이상인,金振浩,金始中 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

거대고리 리간드는 금속이온과 선택적으로 결합하는데, 이를 이용하여 에멀젼 액체막을 통한 금속이온의 이동에 관하여 연구를 수행하였다. 금속이온은 유기층에 있는 운반체에 의하여 source phase에서 receiving phase으로 이동한다. 운반체로는 거대고리 리간드인 DBN_(3)O_(3)를 사용하였다. 여기에서 에멀젼 액체막을 통한 금속이온의 이동에 관한 요인과 어떤 금속이온의 선택적 분리에 관하여 검토하였다. 금속이온과 거대고리 리간드 그리고 금속이온과 receiving phase내에 있는 음이온에 대한 안정도 상수를 금속이온의 선택적 이동에 대한 척도로 조사하였다. 납이온이 혼합 용액에서 다른 금속이온보다 높은 이동속도를 나타내었다. Receiving phase내의 음이온이 금속이온의 이동에 중요한 역할을 한다. Receiving phase내에 있는 NO_(3)^(-)을 S_(2)O_(3)^(2-) 대치하면 이동량이 증가함을 보였는데 이는 Pb^(2-)-S_(2)O_(3)^(2-) 상호작용이 Pb^(2+)-NO_(3)^(-) 상호작용보다 크기 때문이다. Macrocyclic ligand has been know to selectively bind with metal ions so that ability applied for the transport of metal ions across the emulsion liquid membrane in this study. The metal ions are transproted from the source phase to the receiving phase by the carrier of the organic phase. Several factors involved in the transport of metal ions acrose the emulsion membrane we reported here and these factors proveided the informations for the selective seperation of some metal ion. Stability constants for cation-macrocyclic ligand and metal ion-anion receiving phase interaction are examined as parameters for the prediction of metal ion transport selectivities Pb^(2+) was transported higher rates than the other metal ions in the mixture solution. The interaction of metal ion to anion in receiving phase is important. S_(2)O_(3)^(2-) in replacement of NO_(3)^(-) in the receiving phase enhances the transport of pb^(2-) since Pb^(2-)-S_(2)O_(3)^(2-) interaction is greater than Pb^(2+)-NO_(3)^(+) interaction.

방사선치료 조사영역 내에 발생한 설암 환자에서 입체조형방사선치료 경험 : 증례보고

조문준,장지영,김기환,김병국,송창준,김준상,김재성 충남대학교 암공동연구소 2003 암공동연구소 업적집 Vol.3 No.

Objectives : We report an interim result of conformal radiotherapy in a patient with early stage cancer at the base of the tongue, which developed in a previously irradiated area. Materials and Methods : A 64-year-old male patient was diagnosed with T4NOMO supraglottic cancer. He received 72Gy of radiation therapy from 21 November 1988 to 24 February 1989. He had local failure and underwent a salvage total laryngectomy on 28 August 1989. Subsequently, he did well. In early 1999, he suffered from throat pain. He had a 2.5cm ulcerative mass at the base of his tongue, in the area that had been irradiated previously. Biopsy showed squamous cell carcinoma. After workup, he was diagnosed with base of tongue cancer with T2NOMO. Surgery was not feasible because the morbidity was not acceptable. Since it was difficult to re-irradiate the area with a curable dose using conventional 2D radiation therapy with an acceptable morbidity, we decided to try conformal radiotherapy. We used 7 static beam ports with field sizes from 7×6.4 to 8×8㎠, using 6 and 10MV photons. The fractionation regimen was 1.8Gy, 5 times per week. He received 64.8Gy in 36 fractions from 9 April 1999 to 1 June 1999. Results : In the 21 months since radiotherapy, the patient has not experienced any acute or chronic complications, such as xerostomia. He experienced relief of pain shortly after the start of radiotherapy, showed a complete response, and is still doing well. Conclusion : Conformal radiotherapy can be used to treat cancer that develops within a previously irradiated field, with curative intent.

태권도 대학선수들의 찍어차기에 대한 운동학적 특성 분석

김의환,윤상화,조동희,권문석 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose of this study was to analyze toe kinematic variables of Jigeochagi in Taekwando with three dimensional analysis technique and show the kinematic characteristics of it. The subjects of the experiment were Taekwondo players who have been attending in Yong-in university(YIU), and Jigeochagi is their favorite technique, the kicking form was filmed on 16㎜ video camera(30f/s). Kinematic variables were temporal, posture and angular velocity. The mean values were obtained and used as basic factors for examining characteristics of Jigeochagi in Taekwondo. The results of this analysis were as follows, 1. The total time elapsed(TE) of Jigeochagi were 1.45, 1.56 sec. 1ph was fastest in performance showing then 2ph, 3ph. 2. In performing of Jigeochagi, the ankle, knee angle of supporting foot and the ankle, knee angle of attacking foot flexed to MKA then extened to IMP 3. The ankle, knee, hip angular velocities of attacking foot showed negative value to TO and then positive value to MKA and then showed negative value to IMP.

Reciprocal Lattice Explorer의 原理와 使用法

徐日煥,李珍昊,秋錦洪,林星秀,柳保盈,朴晶蘭,金文執,趙素羅,金憲俊,李正秀,成百石 충남대학교 자연과학연구소 1993 忠南科學硏究誌 Vol.20 No.2

Reciprocal lattice explorer는 de Jong-Bouman camera와 Buerger precession camera를 合친것이다. 이 explorer를 使用하면 goniometer에 한번 固定한 試料를 使用하여 그 試料의 空間群을 決定하는데 必要한 모든 寫眞을 撮影할 수 있으며 그들은 찌그러지지 않은 逆格子面의 寫眞들이다. 本 論文에서는 de Jong-Bouman 과 Buerger precession 寫眞術의 原理와 使用法을 記述 하였고 또한 de Jong-Bouman의 振動寫眞과 zeroth layer 寫眞으로부터 11個 Laue群의 識別方法도 提示하였다. The reciprocal lattice explorer is an instrument which incorporates the principles of both the Buerger precession and the de Jong-Bouman methods. On the explorer all photographs which are necessary for a space group determination can be taken with a single setting of a crystal and the photographs show undistorted pictures of the reciprocal lattice planes. In this paper, the principles and the usages of the de Jong-Bouman and the Buerger precession photography are described, and a method of 11 Laue group identification using the de Jong-Bouman oscillation and zeroth layer photographs is shown.

유도 맞잡기 타입과 받기의 신장에 따른 허벅다리걸기의 Kinematic 분석[2]

권문석,김의환,조동희 한국운동역학회 2002 한국운동역학회지 Vol.12 No.2

본 연구는 6년 이상의 유도경력 소유자인 Y.대학교 유도전공자를 대상으로 맞잡기 타입과 받기신장에 따른 허벅다리걸기 동작시 3차원 영상분석법을 이용하여 운동학적 변인의 특성을 분석하는데 그 목적이 있다. 유도 맞잡기 타입과 받기신장에 따른 허벅다리걸기 동작은 비디오카메라 2대를 사용하여 촬영(30frame/sec.)하였으며, 분석을 위한 운동학적 변인들은 시간, 자세, 중심변인이며, 실험 결과에 대한 분석과 논의를 통하여 다음과 같은 결론 및 제언을 얻을 수 있었다. 허벅다리걸기 동작의 맞잡기 타입에 따른 유의한 차이는 3국면 소요시간, 걸기1단계 공격둔부각, 걸기1단계 공격무릎각, 걸기2단계 공격무릎각, 걸기2단계 지지무릎각, 걸기1단계 공격발목각, 걸기2단계 지지발목각에서 유의한 차이(p<.05)를 보였다. 종합해보면, 허벅다리걸기를 수행할 때 맞잡기와 상대신장이 허벅다리걸기 기술에 영향을 미친다는 것을 알 수 있었으며, 상대의 신장이 작을 경우 목 뒤를 잡는 타입 A가 시간이 단축(<.05)되었다. 따라서 경기 중 상대의 신장이 작다면 목 뒤를 잡는 것이 유리하다.이러한 사실들을 종합해 볼 때, 유도 경기 중 허벅다리걸기를 수행할 대 맞잡기가 많은 영향을 주었다. 또한 기술의 핵심단계인 3(걸기)국면에서도 받기신장에 의한 차가 더 크게 나타나 받기신장 역시 많은 영향을 주었다. 단계별 변인들의 변화량에 있어서는 전체적으로 모든 변인들이 변화량에서 큰 차이를 나타내지는 않았다고 할 수 있다. 따라서 맞잡기와 받기신장은 상당한 관계가 있음을 알 수 있었으며 유도 경기 중 상대에 따른 다양한 잡기와 신장을 고려한 기술이 요구된다. This study was to analyze the kinematic variables when the subjects performing Uchi-mata(inner thigh reaping throw) by Kumi-kata types((How to grasp A or B?) and two different opponent's height in Judo. Kinematic variables were temporal, posture. Data analysis was collective comparison of two-way ANOVA, t-test by type A&B and two different opponent's height. There were significant difference of Kumi-kata types(p<.05) in the time elapsed on Kake phase(KP : throwing phase) and hip, knee, ankle-angle of the attacking foot in the 1st stage of KP and knee, ankle-angle of the attacking foot and hip, knee ankle-angle of the supporting foot in the 2nd stage of KP. There were significant difference of two opponent's(p<.05) in the time elapsed on KP and hip-angle of the supporting foot in 1st stage of KP. Therefore, the interaction effect(p<.05) were in the time elapsed on KP and hip-angle of the supporting foot in the 2nd stage of KP. So, It could be suggested that Judoka hold on the part-behind neck lapel(type A) at the sleeve with the other of Judogi jacked when opponent's height was short. Because the time elapsed on KP of type B was not so fast as type A(p<.05) during performed Uchi-mata, and also the bigger hip-angle of the supporting foot in the 2nd stage of KP grew, the faster the time elapsed on KP became.

새로운 매체현실과 문화변화

최문규,김회봉,조경식,서규환 한국독일어문학회 2000 독일어문학 Vol.11 No.-

Der Begriff "Medienrealita¨t" ist heute aktuell geworden. Obwohl die Medien zur Vemittlung der Kommunikation auch in der Vergangenheit sehr verallgemeinert worden sind, gelten sie heute nicht mehr als bloβes Mittel. Die Entwicklung der elektronischen bzw. technologischen Medien vera¨ndert sowohl die Realita¨t unserer Welt als auch das Sein schlechthin. Der Begriff "Medienrealitat" ist synonym mit den anderen Begriffen wie "digitaler Schein" bzw. "virtuelle Realita¨t". "Informationsgesellschaft", die den tradierten Gegensatz zwischen Sein und Schein. dem Wahren und dem Falschen auflo¨st und zu einer neuen "Form der Realita¨t" avanciert werden. Um die Medienrealita¨t zu analysieren. werden im zweiten Kapitel die verschiedenen Elemente illuminiert, durch die neue Medienrealita¨t und Kultur konstituiert werden: ganz neue "immaterielle Basis der Information. Macht der Bilder, Geschwindigkeit, neue computerielle Wahrnehmung. "Medienwerk". Diese Elemente beherrschen sowohl die Realita¨t als auch die Kultur. Abschlieβend wird die Mo¨glichkeit reflektiert. wie die Kunst (besonders die Literatur) die Medienrealita¨t u¨berwinden und ihre alternativen Wege ero¨ffnen kann. Im dritten Kapitel wird der Begriff "virtuelle Realita¨t" philosopisch uberpruft, wobei er die Gemeinsamkeiten mit den tradierten philosophischen Begriffen wie "dynamis, "potentia, "virtualite"~possibi1ite usw. teilt. Auch kann der Widerspruch der "virtuellen Realita¨t" besta¨tigt werden, die vor allem auf der radikalen Vera¨nderung von Technik. Information und Kapital basiert. Das heiβt: es ist ein Widerspruch oder die Verhu¨llung der ontologischen Implikation, daβ die virtuelle Realita¨t durch die allma¨hliche Negierung ihrer Virtualita¨t zur Realita¨t erhoben wird. Im vierten Kapitel wird das Verha¨ltnis der Gesellschaft zu Umwelt. Information und Medien aus der Sicht der Luhmannschen Systemtheorie betrachtet. Daraus ergibt sich. dass die Gesellschaft als Sozialsystem bei ihrer Selbstreproduktion mit der Leitdifferenz von System/Umwelt operiert und damit die elbstreproduktion der Gesellschaft von der Vera¨nderung ihrer Umwelt (Technik, Bewuβtsein, Organismus usw.) abha¨ngig ist. Dabei ist deutlich, dass Medien (Schrift. Buchdruck. Elektronik usw.). die zur Verbreitung der Informationen dienen, bei der Evolution der Gesellschaft eine entscheidende Rolle gespielt haben. Schlieβlich handelt es sich um die unterschiedlichen soziologischen Theorien u¨ber das Verhaltnis von Medien und Gesellschaft. In den Vordergrund treten dabei die Theorien von D. Bell und M. Poster. Bells Theorie der postindustriellen Gesellschaft behandelt die Entwicklung der Technologie. die heute die Kultur und die Gesellschaftsstruktur stark vera¨ndert. Gegen Bell postuliert Poster eine Wende von der Produktionsweise zur Informationsweise, indem er die erwandtschaft mit der postmodernen Theorie teilt. Seiner Perspektive zufolge gilt heute nicht das Kapital. sondern die Information als Hauptmovens der Gesellschaft. Die Medien ko¨nnen weder das Absolute noch die Utopie sein. Was der Euphorie der sog. "idealen Entwicklung der Medien" kritisch gegenu¨berstehen kann. ist nichts anderes als die kritische Reflexion der Kunst.

유도 맞잡기 타입에 따른 허벅다리걸기의 Kinematic 분석 [Ⅰ]

김의환,조동희,권문석 한국운동역학회 2002 한국운동역학회지 Vol.12 No.1

The purpose of this study was to analyze the kinematic variables of Uchi-mata(inner thigh reaping throw) by Kumi-kata(engagement position, basic hold) types A, B in Judo with three dimensional analysis technique and show the kinematic characteristics of it. The subjects of the experiment were judokas who have been attending in Yong-in University(YIU), and Uchi-mata is their tokui-nage(favorite technique), the throwing form was filmed on 16mm video camera( 30frame/sec.) Kinematic variables were temporal, posture, and COG(Center of Gravity). The mean values and the standard deviation for each varibles were obtained and used as basic factors for examining characteristics of Uchi-mata by Kumi-kata types. The results of this analysis were as follows 1) Temporal variables The total time elapsed(TE) of Uchi-mata of types A, B were 1.45, 1.56 sec. respectively. Types A and B were not quite different on every phase. 2) Posture variables In performing of Uchi-mata, the range of flexion in type A, left elbow was 45?and B was 8 9?from Event 2(E2) to Event 6(E6). Type A and B were quite different in right elbow angle in Eventl(E1). Left shoulder angle of type A was extended and type B was flexed in E4. Both types right shoulder angles were showed similar pattern. Also both hip angles(right/left) were showed similar pattern. When type A performed Uchi-mata the knee-angle of supporting foot showed 142?in the 1st stage of kake phase[KP], and extended to 14T in the 2nd stage of KP. And the foot-ankle angle of supporting foot showed 83?in the 1st stage of KP, and extended to 86?in the 2nd stage of KP. moreover, The knee angle of attacking foot showed 12W in the 1st stage of KP, and extended to 132?in the 2nd stage of KP, and the foot-ankle angle of attacking foot showed 10 6?in the 1st stage of KP, and extended to 121?in the 2nd stage of KP. When type B performed Uchi-mata the knee-angle of supporting foot showed 144?in the 1st stage of KP, and extended to 154?in the 2nd stage of KP. And the foot-ankle angle of supporting foot showed 83?in the 1st stage of KP, and extended to 92?in the 2nd stage of KP. moreover, The knee angle of attacking foot showed 132?in the 1st stage of KP, and extended to 140?in the 2nd stage of KP, and the foot-ankle angle of attacking foot showed 103?in the 1st stage of KP, and extended to 115?in the 2nd stage of KP. So, in performing of types A, B, it showed that the type B extended more than type A, but the ankle angle of attacking foot showed dorsiflexion. 3) C. O. G. variables When the subjects performed Uchi-mata, COG of type A, B up and down in vertical aspect was 71cm, 73.8cm in height from the foot in the 2nd stage of KP. The COG of right and left in frontal aspect showed the large move from the left to the right on both types

순간충격시험에 의한 금정산지역 화강암의 수리적 매개변수 산출

함세영,김문수,성익환,이병대,조병욱,김광성,김성이 부산대학교 환경문제연구소 2000 環境硏究報 Vol.18 No.-

This study is aimed for estimating hydraulic parameters using the Cooper-Bredhoeft-Papadopulos, the Hvorslev, the Bouwer & Rice analyses of data obtained by the slug test, and for characterizing hydraulic properties at the test holes in relation to drill core data. The study area was divided into four subareas far which the hydraulic characteristics was considered. The relationship among hydraulic parameters obtained by the three slug test analyses was also considered. The difference of hydraulic conductivity estimates between the injection slug test and the withdrawal slug test seems to be caused by the permeable fracture distribution around the test hole and the disturbance of fine materials in the fractures induced by the pressure variation due to slug injection and withdrawal. The hydraulic conductivity estimates calculated by the Cooper-Bredhoeft-Papadopulos, the Hvorslev and the Bouwer & Rice analyses range from 10-8 to 10-5m/sec, and the average ranges from 10-7 to 10-6m/sec.