해수에 적응시킨 Guppy(Lebistes reticulatus) 신장의 proximal tubule의 미세구조의 변화

김한화,지영득,문영화,강화선,한지원 최신의학사 1991 最新醫學 Vol.34 No.12

무당개구리 정자형성의 세포학적 연구

金翰華,盧鏞泰,池永得,文英花 최신의학사 1982 最新醫學 Vol.25 No.5

송사리 상피의 미세구조적 연구

김한화,지영득,문영호,강화선 최신의학사 1988 最新醫學 Vol.31 No.12

민산초나무 種實의 油脂 및 蛋白質組成에 관한 硏究

윤한교,김지문 충남대학교 농업과학연구소 1976 農業技術硏究報告 Vol.3 No.2

In order to analyze the composition of fatty acid in the seed oil, and amino acid in the seed protein of wild thornless chinese pepper tree; Zanthoxylum schini folum var. inermis Nakai, GLC method and amino acid autoanalyzer were applied, respectively, while the general composition of the seed and physico-chemical properties of the seed oil were also determined by A. O. A. C. method. The results obtained were summarized as follow The content of oil, protein and ashes were 47.05%, 20.14% and 3.1%, respectively. The content of sulfur and cyan compound in the seed were 0.02% and 0.00005%, respectively, which were far below than allowed guantity by food regulation. Therefore, it is considered to be safe for edible purpose. The iodine absorption number obtained was 145.2, which might be belonged to drying oil. The physico-chemical properties of the seed oil such as acid value, saponification number and refractive index showed the characteristics of an unsaturated high molecular fatty acid compound. The seed oil was composed of 34.8% of oleic acid, 25.1% of linoleic acid and 26.1% of linolenic acid, which accounts for more than 80% of essential fatty acid. Therefore, it could be used as an edible oil. Seventeen kinds of amino acids were anayzed from seed protein. Among them comparatively high content of threonine, valine, methionine, isoleucine, leucine and phenylalanine were observed. As a non-essential amino acid, glutamic acid was found as high as 4.985%. From these results the seed of thornless Chinese pepper would be good for oil and protein source.

신발 제조업에의 린 생산방식 도입

윤재홍,송한식,권치명,정문상 東亞大學校 經營問題硏究所 1994 經營論叢 Vol.15 No.-

This paper is concerned with a lean production system to improve the productivity of shoes manufacturing industries. For this purpose, this research first reviews the environmental characteristics of shoes manufacturing industries and invetigates the current problems of shoes production systems. Shoes manufacturing process roughly consists of three process lines shoes uppers line, shoes soles line, and assembling line of shoes uppers and soles. Two major problems in shoes production system are a large amount of work-in-process(WIP) inventories, and the low rate of matching shoes uppers and soles in an assemblying line. Most of shoes manufacturing companies have more than a 3-days WIP inventories in every process line to avoid the blocking the production. Particularly the assemblying line has 5-7days buffers of shoes uppers and soles to maximize the productivity of manufacturing final shoes, however, the matching rate of shoes uppers and soles in the assemblying line is about 50%. These problems are from a low efficiency in inventory control mainly due to (1) too many order specification of sizes, colours, types and different due dates, and (2) a large amount of WIP inventories. To reslove above mentioned problems, we sugggest a lean production system of pull-method for reduction of WIP inventories and improvement of matching rate of shoes uppers and soles in assemblying line. Compared to a push production system(current production system), a pull production system may have a number of adventages in controlling inventories and balanced match of the sole parts and uppers parts when it applied to shoes manufacturing process. As an alternative to control the pull production method, we design a Kaban for production and inventory control. Also we design the Kaban circulations model for the production lines and inventory stores, and a shoes manufacturing information system to incorporate the Kaban system. We expect that the effective adoption of the pull production system to shoes manufacturing system will show better results in improving the matching rate, and reducing the WIP inventories and production lead time. These effects may also give more flexible production planning and raw matiarial procurement planning. We finally consider this research would be helpful in designing the lean shoes production system

초고속 국가망의 가입자망 유형별 정보보호 대응방안

이형옥,조정호,한치문 한국정보사회진흥원 2003 정보화정책 Vol.10 No.1

본 논문에서는 초고속국가망의 가입자별 망구조와 초고속 국가망을 이용하는 기능에 따른 가입자망의 유형을 분석하고, 이를 토대로 초고속국가망에서 가입자망의 정보보호를 위한 보안모델을 제시한다. 이를 위해 가입자망 구조를 FR망 가입자, ATM망 가입자 및 라우터망 가입자로 구분하고, 가입자망의 기능을 인터넷 백본 모델, ATM종단간 전용선 기능인 가상 터널링 모델, VPN모델로 분류한 다음, 각 모델별 가입자 정보보안을 위한 대응 방안을 분석한다. In this paper, subscriber network types in KII(Korea Infornation Infrastructure) accofding to subscriber network structures and the application types of subscriber are analyzed, and the protction models for the user data of subscriber networks on KII are proposed. The subscriber network structures such as FR(Frame Relay) network, ATM network and router network are defined, and the service application model in KII are classified. As a results, user data protection methods suitable for each model are analyzed.

Risperidone 조기 중단군 및 장기 유지군의 임상적 특성 비교

김광수,박원명,전태연,배치운,김대진,백인호,이철,김정수,한상익,최보문,장계호,고효진 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

연구목적 : Risperidone 투여후 조기 중단한 환자들과 장기적으로 계속 risperidone을 복용하고 있는 환자의 임상적 특성을 평가하고 나아가 risperidone장기 유지와 조기 중단의 요인을 분석하고 정신병리가 약물 투여에 미치는 영향을 조사하고자 하였다. 방 법 : 연구 대상자는 1996년 1월부터 1996년 12월까지 가톨릭대학교 의과대학 부속 8개 병원 정신과에서 risperidone을 투여 시작한 환자 580명중 DSM-IV기준에 의해 정신분열병으로 진단받고 투여 기간이 6개월 미만(조기 중단군)이거나 2년 이상(장기 유지군)을 경과하였으며 의무기록의 누락이 없는 210명을 선정하였다. 두 군간 임상적 특성을 조사하기 위하여 인구학적 변인, 정신병리학적 변인, 약물 투여기록 및 부작용 등을 과거 의무기록을 근거로 평가하였다. 결 과 : 대상환자 210명 중 조기 중단군이 67명(31.9%)이었고 장기 유지군은 143명(68.1%)이었으며 두 군간 인구학적 변인과 정신병리학적 변인에 따른 특징에는 두 군간 차이가 없었다. 두 군간 risperidone의 시작 용량과 변인과 정신병리학적 변인에 따른 특징에는 두 군간 차이가 없었다. 두 군간 risperidone의 시작 용량과 최대 용량은 유의한 차이가 없었으나 유지용량은 조기 중단군에서 4.49(±1.44)mg,장기 유지군에서 3.67(±1.50)mg으로 유의한 차이가 있었다(t=3.698, p<0.05). 또한, 이전 항정신병약물의 사용 기왕력 변인에서 조기 중단군은 기왕력이 없는 환자가 39명(58.2%), 고역가 항정신병약물을 사용한 기왕력이 있는 환자는 27명(40.3%), 저역가 항정신병약물을 사용한 기왕력이 있는 환자는 1명(1.5%)이었고, 장기 유지군은 기왕력이 없는 환자가 58명(40.6%), 고역가 항정신병약물을 사용한 기왕력이 있는 환자는 77명(53.8%), 저역가 항정신병약물을 사용한 기왕력이 있는 환자는 8명(5.6%)으로 유의한 차이가 있었다.(x²=6.559, df-=2, p<0.05). 결 론 : 본 연구결과에 의하면 가급적 환자 상태에 따라 낮은 최적 치료 용량을 투여하는 것이 장기잔의 투여를 바람직한 것으로 생각된다. 본 연구와 같은 대규모의 후향적 자연적 연구는 일반 실제 진료에서 risperidone의 효과 및 기타 다른 측면에서의 유용한 정보를 얻을 것으로 기대된다. Objective : This retrospective naturalistic study was designed to compare the clinical characteristics including psychopathology of two groups of patients, long-term maintenance group and short-term drop-out group, who were taking risperidone. Method : Datas were collected for 210 schizophrenic patients with complete medical records among 580 patients who were enrolled with risperidone administration from January 1996 to December 1996 in 8 affiliated hospital of the Catholic University. The short-term drop-out patients group were assigned to whom treatment period was less than 6 month, and the long-term maintained patients group, treatment period was more than 2 years. We assessed demographics, psychopathology, and other variables related with medication based on past medical records. Results : Among subjects of 210, short-term drop-out patients group were 67(31.9%) and long-term maintained patients group were 143(68.1%). Demographics and psychopathology were not significantly different between two groups. The stating and maximal dosage of risperidone was not significantly different between two groups but the maintenance dosage of risperidone was lower in long-term medicated patients group than short-term drop-out patients group(t=3.698, p<0.05). Additionally, the result of this study showed differences in experiences of past antipsychotic use as following. The number of no previous use of antipsychotic was 39(58.2%), the number of high potency amtipsychotic use was 27(40.3%), and the number of no previous use of antipsychotic was 58(40.6%), the number of high potency ntipsychotic use was 77(53.8%), the number of low potency antipsychotic use was8(5.6%) in long-term maintained group.(x²=6.559, df-=2, p<0.05). Conclusions : According to these results, administration of low therapeutic dosage should be recommended for long-term maintenance as if possible. Multi-center based retrospective naturalistic study like this would be useful for getting informations about efficacy and some other aspects of antipsychotic administration in practial field.

신규 세파로스로린 항생제 DWC-751 합성과 물성연구

이재호,정종근,김명구,안상근,최영기,문치장,오세한,성무제,윤길중,신종만,김학형,김영도,박준우 한국응용약물학회 1993 Biomolecules & Therapeutics(구 응용약물학회지) Vol.1 No.1

The synthesis and physicochemical properties of a novel cephalosporin, DWC-751 are described. DWC-751, (6R, 7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[(1-methylbenzotriazol-3-ium)methyl]-ceph-3-em-4-carboxylate monosulfate(IV_a) was conveniently obtained by the conversion of compound(IV) into the crystalline monosulfate. Adjusting pH 4.8-5.2 in aqeous solution of the crude crystalline, compound(IV) in the form of a crystalline pentahydrate was prepared with a high degree of purity. The influence of the various organic and inorganic acids on the solubility of compoud(IV) and its salts, was examined. Particularly, the solubility of DWC-751 was 92 ㎎/㎖ at pH 1.7 and 233 ㎎/㎖ at pH 3.0. DWC-751 showed a broad antimicrobial spectrum against gram-positive and negative bacteria.

Waiting-Time Approximation of Polling System with X / K - Type Cyclic Service

Chi Moon Han,Minoru Akiyama,Yoshiaki Tanaka,Junichi Mizusawa 대한전자공학회 1990 JC-CNSS : Joint Conference on Communications, Netw Vol.3 No.-

A 500 MHz-to-1.2 GHz Reset Free Delay Locked Loop for Memory Controller with Hysteresis Coarse Lock Detector

Chi, Han-Kyu,Hwang, Moon-Sang,Yoo, Byoung-Joo,Choe, Won-Jun,Kim, Tae-Ho,Moon, Yong-Sam,Jeong, Deog-Kyoon The Institute of Electronics and Information Engin 2011 Journal of semiconductor technology and science Vol.11 No.2

This paper describes a reset-free delay-locked loop (DLL) for a memory controller application, with the aid of a hysteresis coarse lock detector. The coarse lock loop in the proposed DLL adjusts the delay between input and output clock within the pull-in range of the main loop phase detector. In addition, it monitors the main loop's lock status by dividing the input clock and counting its multiphase edges. Moreover, by using hysteresis, it controls the coarse lock range, thus reduces jitter. The proposed DLL neither suffers from harmonic lock and stuck problems nor needs an external reset or start-up signal. In a 0.13-${\mu}m$ CMOS process, post-layout simulation demonstrates that, even with a switching supply noise, the peak-to-peak jitter is less than 30 ps over the operating range of 500-1200 MHz. It occupies 0.04 $mm^2$ and dissipates 16.6 mW at 1.2 GHz.