http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
금창구,서재석,남진경,이은주,조정원 충남대학교 약학대학 의약품개발연구소 2010 藥學論文集 Vol.25 No.-
Paclitaxel (PTX) is an anti-cancer agent extracted from the bark of the Pacific yew (Taxus brevifolia). In clinical trials, PTX has demonstrated significant activity against a variety of tumors such as drug-resistant ovarian cancer, metastatic breast cancer, non-small cell lung cancer and AIDS related Kaposi's sarcoma. However, the bioavailability of PTX is mainly limited by cytochrome P450 activity in gut wall and liver, and drug transporters, such as P-gp in gut wall and liver. As well as, PTX is very poor soluble in water (<0.5 mg/L) and other pharmaceutically acceptable solvents. The commercial formulation of PTX consists of micellar solution of the drug in cremophor EL (polyoxyethylated castor oil) containing 50% absolute ethanol. However, it is well known that the use of cremophor EL is associated with hypersensitivity reactions, neurotoxicity and nephrotoxicity and also the solubility of PTX is increasing with the addition of citric acid. Therefore, this study is to optimize the mixing order of individual components for stabilized paclitaxel injection.
Cheong-Gu Cho,문준,김주성,최석봉,Cheol-Hyun Moon,민병철,김상일,박승영 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.10
The effects of annealing on the Gilbert damping constant and the magnetic properties are investigatedin CoFeB films sandwiched by either Ta, Ru, or Pd layers. As the annealing temperatureincreases, the damping constant is found to be slightly decreased first and then, rapidly increased. The minimum damping constant is, thus, obtained with a 300 C-annealed Ta/CoFeB/Ta filmwhile the samples with Ru and Pd layers exhibit their minimum at 200 C. The coercive field alsoexhibits a behavior similar to the damping constant; thus, an empirical correlation between themis proposed.
한 · 중 · 일 · 미 주식시장간 수익률 전이의 비선형성 분석
조정구(Cheong-Gu Cho) 한국무역연구원 2015 무역연구 Vol.11 No.5
In this paper we examine whether asymmetry and/or nonlinearity are significant in the transmission of stock-index returns among equity markets of US, Japan, China and Korea, using daily stock price index data from January 2000 to December 2014. We analyze how the accumulated responses per unit of each market to internal and external return shocks vary with the sign and the size of shocks, by employing a nonlinear local projection model. Empirical tests suggest that transmission elasticities are influenced both by the sign and by the size of return shocks. We find that with a few exceptions at the shorter forecasting horizons, the accumulated responses per unit to negative external return shocks are larger than positive ones of the same size, and that the accumulated responses per unit increase with its absolute size for negative return shock, but decrease for positive one.