제산제 탄산수산화마그네슘의 최적 제조조건 추구 및 분체학적 성질

남진경,이계주 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-

Magnesium carbonate hydroxide (hydrotalcite) was synthesized to pursue the optimum conditions having the highest acid consuming capacity by a Box-Wilson experimental design, and micromeritical properties of samples were evaluated by laser particle size analyzer, SRD, BET system, mercury porosimeter, and several adsorption capacity test. The optimum preparation conditions for hydrotalcite were as followwws: concentration of aluminum hydroxide and magnesium hydroxide 1.17mole, reaction temp. 82.6℃, reaction time 2.32hr, ratio of (Al(OH)_3/Mg(OH)_2 4.25, drying temperature 93.2℃ respectively, and its acid consuming capacity was 286ml/g. the neutralization curve shows that sample whose acid consuming capacity was the highest has the best neutralizing capacity and duration capacity. The crystalline form of the synthesized hydrotalcite was identified with a hexagonal system, and the d (003) spacing value of three samples was large. a part of alumina crystal form was shown at 2θ=18°, 38° in sample 3. The micromeritical properties of the synthesized hydrotalcite has no relation with an acid consuming capacity, and there was a tendency that the higher the acid consuming capacity is the larger the particle size and the narrower the size distribution. The values of pore invasive volume, pore area and specific surface area of sample 1 were small among three samples. Isotherm by BET system forms hyteresis loop and it shows the synthesized hydrotacite was porous. the pore diameter was about 10Å and it verifies mesopore. The adsorption capacity measured by methylene blue has no relation with acid consuming capacity. The adsorption of quinine sulfate in aqueous solutuion was identical with the Langmuir isotherm.

배 과피 분말을 첨가한 쌀쿠키의 품질특성 및 항산화 활성

남진경,박지영,장한별,장혜원 한국식품영양과학회 2023 한국식품영양과학회지 Vol.52 No.1

Due to their tangy flavor and firm texture, pear peels are generally discarded instead of consumed with the fruit. In this study, we evaluate the quality characteristics and antioxidant activity of rice cookies supplemented with the ‘Chuwhangbae’ pear variety peel powder as an alternative use for pear peels. The amounts of pear peal powder added to the cookies were approximately 0, 3, 5, and 7%. No significant differences were observed in the rice cookie densities. Cookies prepared with increasing amounts of pear peel powder content showed decreasing pH value, loss rate, and water content, and increased spread factor and hardness. Moreover, the lightness was decreased, whereas redness and yellowness increased with higher pear peel powder concentrations. The antioxidant capacities of 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radicals increased with higher pear peel powder concentrations. The consumer preference test results showed that the sample supplemented with 5% pear peel powder had the highest scores for color, flavor, texture, and preference. Thus, considering the sensory test results, the optimal mixture ratio was determined to be 5% pear peel powder in the cookies. From a zero-waste point of view and considering the nutritional value, antioxidant properties, and consumer preference, pear peel powder can be used as an efficient resource in rice cookie production. 본 연구에서는 배 과피를 활용하여 쌀쿠키를 제조한 후 품질특성 및 항산화 활성을 알아보았다. 배 과피 쌀쿠키의 밀도는 배 과피 함량에 따른 유의적인 차이가 없었으며, pH는 배 과피 함량에 따라 유의적으로 감소하였다. 배 과피 쌀쿠키의 퍼짐성은 배 과피 함량에 따라 유의적으로 증가하였고, 손실률은 유의적으로 감소한 것으로 나타났다. 배 과피 쌀쿠키의 수분함량은 배 과피 함량에 따라 감소하였다. 배 과피 쌀쿠키의 색도는 배 과피 분말을 첨가할수록 L값은 감소하고 a값과 b값은 증가하는 것으로 나타났다. 배 과피 쌀쿠키의 경도는 배 과피 함량이 증가할수록 증가하였다. 배 과피 쌀쿠키의 DPPH 및 ABTS 라디칼 소거 활성에서는 배 과피 함량이 증가할수록 유의적으로 높은 라디칼 소거능을 나타내었다. 관능평가는 대조군보다 실험군에서 좋은 결과를 나타내었으며, 모든 항목에서 배 과피 분말 5% 첨가 시료가 가장 높은 값을 나타냈다. 따라서 항산화 활성과 관능평가 결과가 우수한 배 과피 분말 5% 첨가 쌀쿠키를 배 과피에 대한 재활용 방안으로 활용할 수 있을 것으로 기대한다. 본 연구 자료는 배 과피의 이용 가능성을 제안하고 업사이클링 식품을 새롭게 개발하는 데 목적이 있다. 배 과피의 가공 방안과 조리법이 다양하게 모색되어 환경개선과 식량문제에 기여할 수 있기를 바란다.

어린이집 만 4세 유아의 순수 놀이공간 및 놀이성과 놀이행동 간의 관계

남진경(Jin Kyung Nam),김명순(Myoung Soon Kim) 한국아동학회 2014 아동학회지 Vol.35 No.2

The purpose of this study was to investigate the relationships between play behaviors and young children`s playfulness in a variety of play space environments. The subjects were 150 4-year old children of 29 mixed-age classes in childcare centers of Seoul and Gyeonggi area. The results were as follows; (1) Their play behaviors differed according to their play environment in terms of classroom spaces. Solitary-active play behaviors were more frequently observed in large play spaces than small. (2) Leading participation, cognitive flexibility, voluntary full immersion, and total playfulness scores correlated negatively with reticent behavior. Leading participation, voluntary full immersion, and total playfulness scores, on the other hand, correlated positively with group play behavior. (3) In small play spaces, leading participation, voluntary full immersion correlated negatively with reticent behavior, but leading participation correlated positively with group play. In middle play spaces, cognitive flexibility correlated negatively with reticent behavior. In large play spaces, voluntary full immersion correlated negatively with parallel play, but leading participation, cognitive flexibility, expressions of joy, voluntary full immersion, and total playfulness score correlated positively with group play.

갈색거저리(Tenebrio molitor) 유충의 산화방지 성분 및 활성

진경남,정은정,김용석 한국식품위생안전성학회 2021 한국식품위생안전성학회지 Vol.36 No.1

식용곤충인 갈색거저리 유충을 기능성 소재로 활용하기 위하여 갈색거저리 유충 추출물의 산화방지 성분 및 활성을 확인하였다. 동결건조한 갈색거저리 유충 분말의 일반 성분은 수분함량 0.80 ± 0.06%, 조회분 3.29 ± 0.03%, 조단백질 54.07 ± 0.24%, 조지방 36.78 ± 0.66%이었다. 갈색 거저리 유충 분말의 ethanol 농도별(95%, 70%, 50%, 물) 추출물의 총 phenolic compounds 함량은 50% ethanol 추출물에서 459.23 ± 1.05 mg/100 g으로 가장 높았으며, 총 flavonoid compounds 함량은 물 추출물에서 19.86 ± 0.69 mg/100 g으로 가장 높았다. 갈색거저리 유충 분말 추출물의 DPPH radical 소거 활성은 70% ethanol 추출물에서 82.60 ± 0.00%로 가장 높았으며, 물, 50% ethanol, 95% ethanol 추출물 순으로 높았다. ABTS radical 소거 활성은 50% ethanol 및 물 추출물에서 각각 97.57 ± 0.16%와 95.33 ± 0.41%로 높게 나타났으며, 유의적 차이는 없었다. 환원력의 경우 물 추출물에서 유의적으로 가장 높았으며, 50% ethanol, 70% ethanol, 95% ethanol 추출물 순이었다. 본 연구결과 갈색거저리 유충의 산화방지 성분의 함량이 많고 산화방지 활성을 우수함을 확인하였으며, 기능성 소재로서 활용할 가치가 있는 것으로 나타났다. In order to utilize edible insect larvae as a functional material, the antioxidant components and activities of Tenebrio molitor larvae extracts were evaluated. The total phenolic content of the extract by ethanol concentration (95%, 70%, 50%, water) of T. molitor larvae powder was the highest in the 50% ethanol extract at 459.23 ± 1.05 mg%, and the total flavonoid content was the highest in the water extract at 19.86 ± 0.69 mg%. The DPPH radical scavenging activity of T. molitor larvae powder extract was the highest in 70% ethanol extract at 82.60 ± 0.00%, followed by water, 50% ethanol, and 95% ethanol extract. The ABTS radical scavenging activity in 50% ethanol and water extract was highest at 97.57 ± 0.16% and 95.33 ± 0.41%, respectively, with no significant difference. Significantly, the reducing power was the highest in water extracts, followed by 50%, 70%, and 95% ethanol extract. The results confirmed the antioxidant components and antioxidant activities of T. molitor larvae have been identified, indicating that it is worth using as a functional material.

LASIK 수술시 Gentian Violet에 의한 일시적 합병증

남우호 ( Woo Ho Nam ) , 진경현 ( Kyung Hyun Jin ) 대한안과학회 2003 대한안과학회지 Vol.44 No.1

LASIK수술 중 각막기질면에 대한 초점광선의 정확도와 고정고리의 사용에 따른 술 후 결과

남우호 ( Woo Ho Nam ) , 진경현 ( Kyung Hyun Jin ) 대한안과학회 2003 대한안과학회지 Vol.44 No.3

바깥놀이터 환경 특성에 따른 유아의 신체활동성 및 놀이행동

김명순,남진경,신보원 한국유아교육학회 2020 정기학술대회 논문집 Vol.2020 No.-

Fe^(+)³과의 혼합물을 이용한 알렌드로네이트의 흡광도 변화

송지근,남진경,조정원 충남대학교 약학대학 의약품개발연구소 2009 藥學論文集 Vol.24 No.-

Alendronate, one of bisphosphonates is widely used in the clinical treatment of systemic metabolic diseases, such as osteoporosis and Paget's disease as well as the sequela of malignancies including hypercalcemia. However, alendronate has no chromophore, so the method of derivatization with FMOC(9-fluorenylmethyl chloroformate) in a citrate buffer(pH 11.9) using HPLC was developed. In this study, we developed UV-VIS spectrophotometric assays for availability, simplicity and cost-effectiveness of the required instrumentation. The stoichiometric ratio of alendronate to Fe^(+3) in the chromophoric complex was determined to be 1:1.

보존료의 가공식품 유형별 사용 현황 연구

정은정,진경남,최현정,정유상,김용석 한국식품위생안전성학회 2020 한국식품위생안전성학회지 Vol.35 No.3

The application of color retention agents (3 items), preservatives (17 items), and bleaching agents (6 items) as food additives in processed foods were investigated by food type. Among color retention agents, sodium nitrite was used the most with 257 cases, mainly in seasoned jeoktal (71.21%), ready-to-eat foods (7.78%), and breads (4.87%). Of the benzoates (1,236 cases) used as a preservative, sodium benzoate showed up most, in 1,215 cases, while 81.16% of these were in beverages such as beverage base (39.51%), mixed beverages (22.47%), and ginseng/red ginseng beverages (8.89%). Grapefruit seed extracts (3,291 cases) were applied to 44 types of processed foods such as sauces (54.65%), liquid tea (10.46%), and other products (5.15%). Ethyl p-hydroxybenzoate (2,957 cases) was applied to products (total 96.44%) such as sauces (92.15%), blended soy sauce (2.77%), and pickled foods (1.52%). Potassium sorbate was applied to a total of 789 cases, mainly pickled foods (40.43%) and processed fishery products (47.15%). All 27 cases of sorbic acid were applied to fish paste (100%). Of the bleaching agents, sodium bisulfite and sodium hydrosulfite were mainly used in confectioneries, breads or rice cakes, and potassium metabisulfite, sodium metabisulfite, and sulfur dioxide were mainly found in alcoholic beverages including fruit wine, while sodium sulfite was mostly used in pickled foods. These results are deemed useful in applying food additives to processed foods.

tert-Butyl Hydroperoxide로부터 유도된 산화 스트레스에 대한 Catechol의 보호효과

신동희,남진경,박창식,고지훈,명평근 충남대학교 약학대학 의약품개발연구소 2009 藥學論文集 Vol.24 No.-

This study was to evaluate the protective effects of the catechol compound of Camellia japonica leaf on the tert-butyl hydroperoxide(t-BHP) induced oxidative injury in mice. To examine the in vitro effects of catechol on oxidative stress, human hepatoma cell line, Hep G2 was used and the tetrazolium dye colorimetric test(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay was employed to monitor cytotoxicity. The in vivo study was carried out by administering catechol(0.01, 0.1, 1mg/kg b.w.) by orally for 5 days before a single dose of t-BHP(1.5 mmol/kg i.p.). When the concentration of catechol pretreatment was increased, the liver MDA level was decreased. It was shown that catechol treatment did not alter the serum levels of the hepatic enzyme markers such as aspartate amino-transferase(AST) and alanine aminotransferase(ALT). Next, expression of antioxidant enzymes in liver after catechol treatment were studied using RT-PCR. The liver mRNA expression for antioxidant enzymes; such as Cu/Zn SOD or extracellular SOD were increased after catechol treatment group. These results suggest that catechol may have a potential role in the prevention of oxidative damage of liver in living organism.