Modified Nance appliance를 이용한 매복치의 교정치료

문철현(Cheol-Hyun Moon),이동근(Dong-Gun Lee) 대한치과의사협회 2007 대한치과의사협회지 Vol.45 No.4

저자들은 modified Nance appliance를 이용하여 환자의 협조에 의존하지 않고 매복된 치아의 교정적인 맹출을 시행하여 양호한 결과를 얻을 수 있었다. 특히 Moon’s appliance를 이용하여 동일 악궁 내에서 약하고 정교한 지속적인 힘을 적용 할 수 있었으며, 힘의 방향을 바꾸기 위한 과정에서 장치 전체를 철거해야 하는 번거로움을 해소 할 수 있었다. Traction of impacted tooth often requires patient compliance to place elastics to surgically exposed impacted tooth. It can be very difficult and time-consuming. The aim of this article was to describe an impacted tooth tractor, Moon s appliance, which was modified from the Nance holding arch appliance. Moon s appliance eliminates patient compliance and generates a light continuous force. We achieved the desired treatment results for impacted tooth using this appliance. This new fixed appliance can be a reasonable alternative to conventional appliances.

人命救助의 法的 考察

문현철 朝鮮大學校 法學硏究所 2001 法學論叢 Vol.7 No.-

Riluzole의 칼슘전류 억제효과에 관한 연구

문철현,김형찬 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

Riluzole is a recently synthesized antiglutarnate drug which has the potential therapeutic effect in amyotrophic lateral sclerosis(ALS). The aims of this experiment are to elucidate the pharmacological effect of riluzole on the calcium channels in bovine adrenal chromaffin cells and to verify the mechanism of pathogenesis of ALS, The authors recorded and analyzed the calcium currents of bovine adrenal chromaffin cells in the presence of riluzole by using whole-cell patch clamp technique. The results are as follows. 1. ICa.max was recorded at a voltage of 10 mV. 2. Riluzole inhibited ICaPK & ICaSS of bovine adrenal chromaffin cells. 3. There was a dose-dependent manner in the inhibiting rate of riluzole tested on calcium currents. 4. Inhibitory effect of riluzole on the ICaSS was greater than that on the ICaPK. Therapeutic effect of riluzole in amyotrophic lateral sclerosis seems to be related with the mobilization of calcium ions through voltage-gated calcium channels.

프롤린 함량 증가 및 내건성 강화 관련 새로운 RING-Type E3 유비퀴틴 리가아제 애기장대 atrzf1 돌연변이체의 생리적 기능 연구

주현우,민지희,정문수,김철수 전남대학교 농업과학기술연구소 2021 농업생명과학연구동향 Vol.59 No.-

The covalent attachment of ubiquitin to proteins plays a fundamental role in the regulation of cellular function through biological events involving abiotic of biotic stress responses, immune responses, and apoptosis, Here, we characterize the biological function of the Arabidopsis thaliana RING Zinc Finger 1 (AtRZF1) in dehydration response. AtRZF1 was significantly reduced by drought stress. The atrzf1 mutant was less sensitive to osmotic stress than the wild-type during early seedling development, wheareas transgenic pants overexpressing AtRZF1 were hypersensitive, indicating that AtRZF1 megatively regulates drought-mediated control of early seedling developmeng. Moreover, the ectopic expression of the AtRZF1 gene was very significantly influential in drought sensitiv parameters including proline content, water loss, membrance ion leakage and the expression of dehy-dration stress-relat genes. ARZF1 is a functional E3 ubiquitin ligase, and its conserved C3H2C3-type RING domain is likely important for the biological function of AtRZF1 in drought response. Together, these results suggest that the E3 ligase AtRZF1 is an important regulator of water deficit stress during early seedling development.

구강조건과 유사용액에서 치과용 소와열구 전색제의 잔류 단량체 용출

문현정,이용근,임범순,김철위 대한치과기재학회 2000 대한치과재료학회지 Vol.27 No.1

The estrogenic effect of Bisphenol A (BPA) was targeted because BPA can be present as an impurity in resins (Bis-GMA), or as a degradation product from other resins. 75% ethanol was used as a food-simulating liquids, similar liquid as oral environment, and solubility parameter of which matches that of resin. The purpose of this study was to identify and quantify BPA, TEGDMA, UDMA, Bis-GMA, and degradation product of Bis-GMA that might be released from seven resin-based pit and fissure sealants (CON ; Concise, PFS ; Pit & Fissure Sealant, ELT ; Elite, FSF ; Fissurit F, TMF ; Teethmate F1, UXF ; Ultraseal XT Plus, and HEL ; Helioseal). Specimens were embeded in 1 mm (T) x 5 mm (D) molds then cured and were immersed in 75% ethanol (EH) and artificial saliva (AS) for 1, 7, 14, 21, and 28 days. The extracts were analyzed by HPLC. All the components except BPA were leached highly at the initial stage, so the amount of component leached was not linear with the immersion time. In AS, only TEGDMA was leached. There were significant differences in the amount of eluted TEGDMA depending on the solution (p<0.05) in CON, PFS and ELI group (p<0.05). The amount of eluted BPA was various depending in the sealant (0.023∼2.790 ㎍/㎎). TEGDMA was leached highly from ELI, CON, and HEL in both EH and AS. Bis-GMA was leached from all the sealants, whereas UDMA was leached only from PFS, ELI, FSF, and UXP. The detected amount of BPA and the content of Bis-GMA was not correlated (p>0.05). Bis-GMA did not seem to be decomposed to BPA during the 28 days immersion period. EH penetrates the matrix of pit & fissure sealant, which has been shown to maximize the elution of resin components.

중합 및 미중합 소와열구 전색제의 잔류 단량체 용출에 관한 연구

문현정,임범순,김철위 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

Triethyleneglycol dimethacrylate(TEGDMA), Bis-glycidyl dimethacrylate(Bis-GMA), and Urethane dimethacrylate(UDMA) are components of dental resin-based pit & fissure sealants which may be released and enter the body via skin, dentin and pulp. A recent study reported that hormone-mimicking compound, Bisphenol-A leached into saliva from dental pit & fissure sealants. The purpose of this study was to identify and quantify Bisphenol-A and other leachable components that might be released from polymerized and unpolymerized dental pit & fissure sealants. Seven commercially available light-cured resin-based pit and fissure sealants as the experimental group(Concise, Pit & Fissure sealant, Elite, Fissurit F, Teethmate F-1, Ultraseal XT Plus and Helioseal) and one composite resin (Z100) as the control group were studied. Specimens were polymerized by using a 1 mm (thickness) x 0.5 mm (diameter) acrylic mold which were weighed and immersed in 99.99% ethyl alcohol for 4 min, 2 and 12 hrs., 3 and 7 days. Solutions were analyzed by using High-Performance Liquid Chromatography(HPLC) to detect various leachable components. Three specimens of each sealants were tested. From the experiment, the following results were obtained : Specimen peaks with retention times of 2.28, 3.37, 6.18 and 7.39 min were identified as BPA, TEGDMA, UDMA, and Bis-GMA respectively. BPA was not detected in eluates from unpolymerized specimens(CON, ELI, HEL, Z100). PFS and ELI leached significantly more BPA than other specimens did(p<0.05). Generally, the quantity of TEGDMA leached as a function of aging periods showed no statistically significant difference(p>0.05), but in TFI and UXP group, they showed statistically significant difference after 7 days(p<0.05). The amount of Bis-GMA and UDMA elution after 3 days showed statistically significant difference(p<0.05). The monomers(BPA, TEGDMA, Bis-GMA, and UDMA) of pit and fissure sealants were leached within a range of 0.0023∼2.94% of the original weight of the sealants cured for 4 min, 2 and 12 hours, 3 and 7 days.

치과용 소와열구 전색제의 조성 용출에 관한 실험적 연구

문현정,임범순,김철위 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

From the recent study, it has raised controversy and concern about an estrogenic chemical, bisphenol-A, which was released from resin-based dental pit and fissure sealants. The purpose of this study was to identify and quantify bisphenol-A and other key leachable components that might be released from dental pit and fissure sealants. Five commercially available light-cured resin-based pit and fissure sealants were studied (CON, PEI, ELI, FSF, and TFI). Specimens were prepared from approximately 50㎕ of each pit and fissure sealants. After curing, specimens were weighed and immersed in two different solution (deionized water and 99.99% ethyl alcohol) for 5 hrs. solutions were analyzed by using High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Mass Spectroscopy (MS), and Ultraviolet Spectrophotometer (US) to detect various leachable components (bisphenol-A ; BPA, triethyleneglycol dimethacrylate ; TEGDMA, bis-glycidyl dimethacrylate ; Bis-GMA). There specimens of each sealant were tested. From the experiment, the following results were obtained : In deionized water, peak with retention time of 2.70 min was identified as TEGDMA and the amount of TEGDMA elution from specimens showed statistically significant difference (p<0.05). In ethyl alcohol, peaks with retention times of 2.70 and 6.04 (4.80) min were identified as TEGDMA and Bis-GMA (UDMA), respectively. TEGDMA eluted from CON, PIF, and ELI showed no statistically significant difference (p>0.05). Also, Bis-GMA eluted from CON, ELI, and FSF showed no statistically significant difference(p>0.05). However bisphenol-A was detected at PIT specimen in ethyl alcohol (retention time : 2.51 min in HPLC and 8.02 min in GC-Mass.). The monomers of pit and fissure sealants were leached within a range of 0.04∼1.94 % of the original weight of the cured sealant for five hours.

콤포짓트 레진의 중합체계에 따른 중합률 및 잔류단량체 유출

문현정,임범순,이용근,송재경,김철위 대한치과기재학회 2001 대한치과재료학회지 Vol.28 No.2

Newly developed curing units for the dental composite resins are claimed to result in optimum properties and short curing time. The purpose of this study was to detemine the curing effectiveness of the curing units, and to evaluate the relationship between the degree of polymerization and leachability of residual monomer. Three composite resins were tested (Z100; z100, Herculite XRV; HX, Heliomolar; HM). Disk specimens of 2 mm in thickness and 6 mm in diameter were cured with a plasma arc [Apollo 95E; at 1370 mW/㎠, for 5 sec.(A5), 10 sec.(A10), 15sec(A15)], halogen lamp [VIP; at 500 mW/㎠, for 13 sec.(V13), 26 sec.(V26), 40 sec.(V40)] and custom made light emitting diode [LED; at 500 mW/㎠, for 13 sec.(L13), 26 sec.(L26), 40 sec.(L40)]. Specimens were immersed in 75% ethanol for 7 days. Eluates of the composites were analyzed by a high-performance liquid chromatography, and the degree of polymerization of composites were determined by a Fourier transform infrared spectroscopy. To obtain the sufficient curing by a plasma arc, the curing time should be longer than 10 sec. When the same light energy was irradiated, LED showed similar curing performance to halogen lamp. The light energy and the degree of polymerization was not correlated (p>0.05), but the light energy and the leachability of residual monomer was correlated (p<0.05). The leachability of residual monomer (TEGDMA+BisGMA) depended on the degree of polymerization.

過蓋咬合, 開咬合 및 正常咬合의 咬筋沈默期에 關한 硏究

문철현,정현수 대한치과교정학회 1987 대한치과교정학회지 Vol.17 No.1

The present study was carried out to investigate the relationships between the depth of overbite and the masseteric silent period. Normal subjects of 44 were selected, which consisted of 9 open bites, 24 normal overbites and 11 deep bites, all were 19-29 years of age. EMG activity was recorded on the bilateral masseteric muscles and craniofacial radiography was done. The following results were obtained. 1. The mean duration of masseteric silent period was 18.58±4.50 msec in open bite, 17.37±7.05 msec in normal overbite and 19.30±7.62 msec in deep bite groups. 2. There were no significant differences on masseteric silent period among open bite, normal overbite and deep bite groups. 3. There were no significant correlations between masseteric silent period and craniofacial variables.

防災行政組織에 關한 硏究 : 문제점과 개선방안을 중심으로 Centering on Problems and Solutions

文炫喆 朝鮮大學校 法學硏究所 2000 法學論叢 Vol.6 No.-