運動負荷前後 肥滿女中生의 血中 Glucose, Insulin 및 Apolipoprotein 代謝變化

김태운,신군수,김종인,이광무,김성헌,안병철,고기준 釜山大學校 附設 體育科學硏究所 1994 體育科學硏究所 論文集 Vol.10 No.-

The purpose of this study was to determin a study on the change of blood glucose, insulin and apolipoprotein metabolism before and after maximal exercise in obese middle School girls. The subjects were included 2 groups (each group n=6) : obese group, non-obese group. The measurement variables were blood glucose, insulin and apolipoprotein before and after maximal exercise. The conclusion of this study was as follows: 1. Changes in glucose 1) Obese group had no significant differences by maximal exercise. 2) Non-obese group has been increased significantly by maximal exercise (P<.05). 3) No significant difference was found between two groups. 2. Changes in insulin 1) Obese group had non-obese group had no significant differences by maximal exercise. 2) Obese group has been increased significantly when comparing with non-obese group (P<.05). 3. Changes in apoliporprotein 1) Two groups in Apo-AI has been increased significantly pre and post maximal exercise(P<.05). 2) No significant difference on Apo-AI was found between two groups. 3) Obese group and non-obese group in Apo-B had no significant differences by maximal exercise. 4) No significant difference on Apo-B was found between two groups.

성상신경절 차단 후 발생한 경부 혈종 및 혈흉 : 증례보고

고우석,임경준,유병식,임영재,조성일 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

The stellate ganglion block is one of the most frequently performed blocks in the pain clinic due to its wide range of indications and its simplicity. But it has a potential to cause severe complications because there are some major vessels and nerves around the stellate ganglion. We experienced a rare case of intrathoracic bleeding and hematoma in neck after stellate ganglion block. A 61-years old female patient admitted to ER because of breathing difficulty. She was taken stellate ganglion block in local pain clinic 6 hours before the admission to ER. The patient complained of pain in the neck and dyspnea. We confirmed severe hematoma and contrast leakage in thyroid region and hemothorax. So we applied a endotracheal intubation for the airway insurance and surgical hematoma removal and vessel ligation were done. The patient was discharged from hospital after the treatment of pharyngeal and laryngeal hematoma and hemothorax without further problem or complications after 22 days.

비만 여중생과 정상 여중생의 혈중지질 비교분석

김태운,신군수,김종인,이광무,김성헌,안병철,고기준 釜山大學校 附設 體育科學硏究所 1995 體育科學硏究所 論文集 Vol.11 No.-

The purpose of this study was to analyze and identify the serum lipids of the middle school girls in order to utilize them as the basic data for the prevention of the middle school girls against arteriosclerosis and diabetes tending to lower age. We used total of twelve middle school girls as subject and devided them into two groups : obese group(n=6), normal group(n=6). The measurement items were the Total-cholesterol, HDL-cholesterol, LDL-cholesterol, TG, FFA. The conclusion of this study was as follows : 1. Total-cholesterol 1) All two groups was a little increased by maximal exercise, but there was no significant difference statistically. 2) Normal group was a little higher than obese group, but there was no significant difference. 2. HDL-cholesterol 1) All two groups was a little increased by maximal exercise, but there was no significant difference. 2) In comparison of two groups, normal group was a little high on empty stomach and obese group was a little high before and after exercise, but there was no significant difference. 3. LDL-cholesterol 1) All two groups was a little increased on post-exercise than pre-exercise, but there was no significant difference statistically. 2) In comparison of two groups, normal group was a little higher than obese group, but there was no significant difference. 4. Triglyceride 1) All two groups was a little increased by maximal exercise, but there was no significant difference. 2) In comparison of two groups, normal group was a little higher than obese group on empty stomach and obese group was a little higher than normal group on pre and post-exercise, but there was no significant difference. 5. T-chol./HDL-chol. 1) All two groups was a little increased by maximal exercise, but there was no significant difference. 2) In comparison of two groups, normal group was a little higher than obese group, but there was no significant difference. 6. Free Fatty Acid 1) All two groups was a little decreased by maximal exercise, but there was no significant difference. 2) In comparison of two groups, obese group was a little higher than normal group, but there was no significant difference.

Effect of β-carotene on Cell Growth Inhibition of KB Human Oral Cancer Cells

Sung-Su Yang,Su-Gwan Kim,Byung-Sun Park,Dae-San Go,Sun-Kyoung Yu,Chun Sung Kim,Jeongsun Kim,Do Kyung Kim 대한구강생물학회 2016 International Journal of Oral Biology Vol.41 No.3

β-carotene is present in carrots, pumpkins, and sweet potatoes. It suppresses many types of cancers by regulating cellular proliferation and apoptosis through a variety of mechanisms. However, the effects of β -carotene on oral cancer cells have not been clearly established. The main goal of this study was to investigate the effects of β-carotene on cell growth and apoptosis in oral cancer cells. Our results demonstrate that treatment with β-carotene induced inhibition of cell growth, and that the effect was dependent on β-carotene treatment time and concentration in KB cells. Furthermore, treatment with β-carotene induced nuclear condensation and fragmentation in KB cells. β-carotene promoted proteolytic cleavage of procaspase-3, -7, -8 and –9 with associated increases in the concentration of cleaved caspase-3, -7, -8 and –9. In addition, the level of cleaved PARP was increased by β-carotene treatment in KB cells. These results suggest that β-carotene can suppress cell growth and induce apoptosis in KB human oral cancer cells, and that it may have potential usefulness in anti-cancer drug discovery efforts.

First report of cross-species transmission of deer hepatitis E virus to a guanaco in Korea

Byung-Joo Park,Ji-Hyung Yi,Hee-Seop Ahn,Sang-Hoon Han,Yong-Hyun Kim,Hyeon-Jeong Go,Dong-Hwi Kim,Joong-Bok Lee,Seung-Yong Park,Chang-Seon Song,Sang-Won Lee,In-Soo Choi 한국예방수의학회 2017 예방수의학회지 Vol.41 No.3

The hepatitis E virus (HEV) is a leading causative agent of acute hepatitis in humans. Zoonotic HEV strains have been isolated from several animal species, including pigs. New HEV variants have been recently isolated from camels in the Middle East. In the present study, fecal samples from fallow deer, formosan deer, alpaca, and guanaco were analyzed for the detection of HEV. One HEV strain was detected from guanaco, a species of camelids. The nucleotide sequence of guanaco HEV was identical to those of deer HEV-3 strains, which implied the cross-species transmission of HEV-3 from deer to guanaco.

사람 구강암세포 KB에서 bavachin에 의한 세포성장 억제

박병수 ( Byung Soo Park ),김진수 ( Jin Soo Kim ),고대산 ( Dae San Go ),김수관 ( Su Gwan Kim ),오지수 ( Ji Su Oh ),서요섭 ( Yo Seob Seo ),김춘성 ( Chun Sung Kim ),김도경 ( Do Kyung Kim ) 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.1

Psoralea corylifolia is widely distributed over southeastern Asian countries and has been used in traditional Chinese medicine. Bavachin, one of the main constituents of P. corylifolia, possesses various biological activities such as inhibition of platelet aggregation, anti-oxidation, and anti-bacterial activity. However, the anti-cancer activity of bavachin has not yet been well defined. In this study, the cytotoxic activity of bavachin and its mechanism of cell death were examined in KB human oral cancer cells. Treatment of KB cells with bavachin cells induced inhibition of cell growth in a concentration- and a time-dependent manner as determined by MTT assay. Treatment with bavachin induced nuclear condensation and DNA fragmentation in KB cells. Proteolytic processing of caspases-3, -7, -8, and -9 was elevated by bavachin treatment in KB cells. These results suggest that bavachin can induce suppression of cell growth and cell apoptosis in KB human oral cancer cells, and thus it may have potential effects for anti-cancer drug discovery.

스냅스루 좌굴을 이용한 미소스위치의 설계, 제작 및 실험

고정상,조영호,곽병만,박관흠,Go, Jeung-Sang,Cho, Young-Ho,Kwak, Byung-Man,Park, Kwan-Hum 대한기계학회 1996 大韓機械學會論文集A Vol.20 No.2

A snapping-beam microswitch has been designed, fabricated and tested. From a design analysis, necessary and sufficient conditions for a snap-through switching fouction have been derived for a clamped shallow beam. The necessary condition has resulted in a geometric relation, in which the ratio of beam thickness to initial beam deflection plays a key role in the snapping ability. The sufficient condition for the snapping action has been obtained as a function of the inertia force due to applied acceleration, and the electrostatic force, adjustable by an inter-electrode voltage. For experimental investigations, a set of microbeams of silicon dioxide/$P^+$silicon bimorphs have been fabricated. Geometric size and mechanical behavior of each material film have been measured from on-chip test structures. Estimated and measured characteristics of the fabricated devices are compared.

A clinical study on herpes zoster during the four-year-period (2007-2011)

( Sang Yoon Lee ),( Jae Wan Go ),( Shin Han Kim ),( Byung In Ro ),( Han Kyoung Cho ) 대한피부과학회 2011 초록집 Vol.49 No.20

Prediction of Resistance to Standard Intravenous Immunoglobulin Therapy in Kawasaki Disease

Sang Min Lee,Jeong Bong Lee,Young Bin Go,Ho Young Song,Byung Jin Lee,Ji Hee Kwak 대한심장학회 2014 Korean Circulation Journal Vol.44 No.6

Background and Objectives: Ten to twenty percent of children with Kawasaki disease (KD) do not respond to initial intravenous immunoglobulin (IVIG) treatment. If untreated, approximately 15% to 25% of KD patients have complications. The aim of this study was to find useful predictors of responsiveness to initial IVIG treatment in KD. Subjects and Methods: We retrospectively reviewed medical records of 91 children diagnosed with KD at Myong Ji Hospital from March 2012 to April 2014. Before and after (24 hours to 36 hours) IVIG treatment, the following laboratory data were obtained: hemoglobin (Hb) level, white blood cell count, proportion of neutrophil, lymphocyte and eosinophil, platelet count, erythrocyte sedimentation rate (ERS), Creactive protein (CRP), creatine kinase (CK), creatine kinase MB (CK-MB), and N-terminal pro-brain natriuretic peptide (NT-proBNP). Subjects were then divided into two groups: IVIG-responsive or IVIG-resistant. Results: Of 91 patients, 11 (12%) required retreatment. By univariate analysis, before-IVIG laboratory parameters of white blood cell count, % neutrophil, ERS, CRP, sodium, CK, CK-MB, and NT- proBNP were significantly different between IVIG-responsive and IVIG-resistant patient groups. In the after-IVIG laboratory parameters, Hb level, white blood cell count, % neutrophil, % lymphocyte, CRP, CK, CK-MB, and NT-pro- BNP were significantly different between the two groups. While the mean-differences were not statistically significant, fractional change (FC)-CRP and FC-% neutrophil showed significant difference. By multivariate analysis, FC-CRP was confirmed to be an independent predictor for initial IVIG resistance. Conclusion: Fractional change-C-reactive protein might be a useful and important value for predicting initial IVIG resistance in KD patients.

Pathogenesis of Human Norovirus Genogroup II Genotype 4 in Post- Weaning Gnotobiotic Pigs

( Byung-joo Park ),( Soon-tag Jung ),( Changsun Choi ),( Jinjong Myoung ),( Hee-seop Ahn ),( Sang-hoon Han ),( Yong-hyun Kim ),( Hyeon-jeong Go ),( Joong-bok Lee ),( Seung-yong Park ),( Chang-seon Son 한국미생물 · 생명공학회 2018 Journal of microbiology and biotechnology Vol.28 No.12

Norovirus is the most common cause of acute gastroenteritis. Its pathogenesis is poorly understood owing to the difficulty of establishing viral infection in animal models. Here, postweaning gnotobiotic pigs were infected with human norovirus genogroup II genotype 4 (HuNoV GII.4) to investigate the pathogenesis and replication of the virus. Three groups of four pigs were infected with 1 × 10⁵, 1 × 10⁶, or 1 × 10⁷ genomic equivalent (GE) copies of HuNoV GII.4. Four pigs were used as negative controls. Blood and rectal swab samples were collected after viral infection, and gross legions were examined after necropsy. Diarrhea was induced in 25% and 75% of pigs infected with 1 × 10⁶ and 1 × 10⁷ GE copies, respectively. Viral shedding was detected in 50%, 75%, and 50% of pigs infected with 1 × 10⁵, 1 × 10⁶, and 1 × 10⁷ GE copies, respectively. Viremia was detected in 25% of pigs infected with either 1 × 10⁶ or 1 × 10⁷ GE copies. When gross lesions of gastroenteritis were investigated, the ileum walls of the infected pigs were thinner than those of the controls. Villi atrophy and inflammatory cell infiltration were identified in the ileum of each infected pig. Viral capsid was identified in the jejunum, ileum, colon, spleen, and mesenteric lymph node. Virus replication was newly verified in the spleen and mesenteric lymph nodes by detection of negative-sense viral RNA. In conclusion, HuNoV GII.4 could induce acute gastroenteritis and replicate in the extraintestinal lymphoid tissues in post-weaning gnotobiotic pigs. Therefore, such pigs would be a suitable animal model for studying the pathogenesis and replication of HuNoV.