측방교합유도 형태에 따른 저작형태의 분석

김오영 ( O Young Kim ),이재훈 ( Jae Hoon Lee ) 조선대학교 치의학연구원 2009 口腔生物學硏究 Vol.33 No.1

Case series of maxillary anterior bone augmentation with a novel biphasic calcium phosphate: a clinical and radiographic pilot study

이재홍,Eun-Hee Jung,Hyun-Wook An,Jae-Seung Im,Dong-Won Lee,Jeong-Ho Yun 조선대학교 치의학연구원 2022 Oral Biology Research (Oral Biol Res) Vol.46 No.4

The purpose of this pilot case series was to evaluate the clinical and radiographic outcomes of employing newly developed alloplastic biphasic calcium phosphate (BCP) in guided bone regeneration (GBR) for maxillary anterior peri-implant defects. Six peri-implant dehiscence defects were grafted with BCP. For all included treatment sites, clinical (defect width [DW] and defect height [DH]), radiographic (horizontal hard tissue thickness [HT]), patient discomfort, and early wound healing outcomes were evaluated. At reentry surgery, all surgical sites indicated a change in DW, DH, HT0, HT1, HT2, and HT3 from 4.08±1.39 mm to 1.13±1.76 mm, 3.57±1.42 mm to 0.58±1.09 mm, 2.18±0.66 mm to 1.50±0.53 mm, 2.11±0.57 mm to 1.73±0.28 mm, 2.22±0.54 mm to 1.75±0.26 mm, and 2.63±0.87 mm to 1.83±0.46 mm, respectively. Significant differences were discovered between paired DW and DH (p<0.05), whereas radiographic parameters had no significant differences. The severity of pain and swelling was 4.8±1.9 and 6.5±1.9, respectively, and the duration of pain and swelling was 4.5±3.8 and 5.8±2.9 days, respectively, according to early postoperative discomfort assessment. No adverse reactions occurred at any treatment site. In terms of clinical and radiographic outcomes, the newly developed BCP is acceptable biocompatible and suitable for the GBR of maxillary anterior peri-implant dehiscence defects within the limitations of this study.

Necessity of miniplate removal after orthognathic surgery

( Han Seung Jang ),( Su Gwan Kim ),( Ji Su Oh ) 조선대학교 치의학연구원 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.1

Purpose: The purpose of this article was to examine the necessity of miniplate removal following orthognathic surgery. This was accomplished through a retrospective study and an article review. Materials and Methods: Patients who underwent orthognathic surgery since 2003 at the Department of Oral and Maxillofacial Surgery of Chosun University Dental Hospital (Gwangju, Korea) were investigated. Patients` age, sex, surgery type, and reason for plate removal were examined. Results: In total, 522 patients were investigated, and 67 patients (13%) had their plates removed. It was revealed that 38 patients (57%) wanted to receive the surgery without any particular reason. Conclusion: There was no reason for removal of the plates if the patients were not already experiencing complications.

Removal of miniplates following facial trauma and orthognathic surgery: a 3-year study

Na-Ra Shin,오지수,신상훈,김수관 조선대학교 치의학연구원 2018 Oral Biology Research (Oral Biol Res) Vol.42 No.4

The purpose of this study was to determine the cause and risk factors of removing bone plateby investigating and analyzing 359 patientswho underwent reduction of fracture or orthognathic surgery with bone plate insertion over the past 3 years. Patients were evaluatedwith respect to age, smoking status, reason for insertion of plates, the numbers of inserted plates, sites of insertion, time betweeninsertion and removal, reasons for removal of plates. The removal rate of bone plates was 33.1%. Of these, 17.0% of patients had clinicalsymptoms which led to remove plates. The removal rate of men was 29.9% and the rate of women was 39.2%. There were high removalrates from less than 20s (45.8%) and 20s (34.4%) those who are relatively young age group. On the other hand people in their 50s hada removal rate of 27.8% which was higher than those in their 60s with a rate of 20.7%. The removal rate of bone plate inserted into themandible was 33.5%, and the removal rate of bone plate inserted into the maxilla was 34.7%. The mean period between the insertionand removal of bone plate was 10.9 months. The main reason for the removal of bone plate was the patient's requirement (44.5%). Themost common cause of clinical symptoms was infection (22.7%). Infection was manifested within about a year and led to the platebeing removed. Therefore, lowering the possibility of infection after surgery could decrease the removal rate of bone plate.

Clinical evaluation of implants survival rate: Eight-year retrospective study

( Su Yong Jeon ),( Woo Hyuk Yun ),( Ha Na Hyun ),( Hee Yung Chang ),( Hyung Keun You ),( Sung Hee Pi ) 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.1

Purpose: Since endosseous implants are used for the treatment of various types of tooth loss, they are considered a primary therapeutic options. Many studies regarding implant survival rates have been published. However, there have been few long-term studies on implant survival rate in Koreans. Therefore, the aim of this study was to examine implant survival rate for 8 years as well as identify potential risk factors for failure. Materials and Methods: The present study included 535 implants in 332 patients at the Department of Periodontology of Wonkwang Dental Hospital. By means of a chart review, 1) implant site, 2) age and sex of patients, 3) diameter and length of placed implant, 4) advanced technique at recipient site, 5) periodontal treatments before implant therapy, and 6) systemic diseases such as diabetes mellitus, hypertension, or osteoporosis were recorded. The effects of evaluated variables on implant failure were analyzed using chi-square test. Statistical significance was accepted at p<0.05. Results: The present study showed an implant survival rate of 97.76%. Overall, 12 of 535 (2.24%) implants were explanted. Two explanted implants were in the maxillary anterior area, five were in the maxillary posterior area, and five were in the mandibular posterior area. The average time from placement to explantation was 11.92±15.30 months. None of the investigated factors was significantly associated with implant failure (p>0.05). Conclusion: Survival rate in this study was 97.76%. Despite the lack of significant association between implant failure and associated factors, there are potential risk factors. Cautious diagnosis and treatment planning are needed.

Histomorphometric evaluation for osseointegration after particulated-dentin coated implant placement

( Jae Seek You ),( Su Gwan Kim ),( Ji Su Oh ),( Sung Chul Lim ),( Jae Sung Kim ) 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.1

Purpose: The purpose of this study was to evaluate osseointegration after placement of a machined surface implant and particulated-dentin-coated implant in a canine model. Materials and Methods: Four dogs were randomly assigned to two groups, and each group was further divided into two subgroups 4 and 8 weeks after implantation. The implant was placed under different conditions. Group 1 included the machined surface implant and group 2 included the particulated-dentin-coated implant. Histologic sections and histomorphometric analysis were obtained 4 and 8 weeks after surgery. Results: Group 2 showed a higher bone-implant contact rate and bone formation rate than group 1 in the 8 week group. In group 2, the 8 week group revealed significant elevation of both bone-implant contact rate and new bone formation rate versus the 4 week group. Conclusion: According to these results, particulate-dentin-coated implants can provide satisfactory stability and increase the quantity and maturity of new bones in the later stages of implant placement.

Effects of cimifugin on cell growth inhibition and cell apoptosis induction in fadu human pharyngeal squamous cell carcinoma

Jong-Hyun Park,김도경 조선대학교 치의학연구원 2022 Oral Biology Research (Oral Biol Res) Vol.46 No.4

Cimifugin is an important component of chromones in the dry roots of Saposhnikovia divaricata and is used in treating inflammatory diseases. However, the effect of cimifugin on cancer is unclear. The aim of this study was to investigate the effects of cimifugin on cell apoptosis induction in FaDu human pharyngeal carcinoma cells using MTT assay, live/dead cell assay, and western blot. Cimifugininduced FaDu cell death in a dose-dependent manner. Cimifugin-induced apoptosis in FaDu cells was mediated by the expression of Fas and activation of caspase-8, caspase-3, and poly (ADP-ribose) polymerase (PARP). Western blot results showed the downregulation of Bcl-2 and Bcl-xL but the upregulation of Bad and Bax by cimifugin in FaDu cells. These results suggest that cimifugin inhibits cell survival and induces apoptotic cell death in FaDu human pharyngeal carcinoma cells via both the death receptor-mediated extrinsic apoptotic pathway and the mitochondria-mediated intrinsic apoptotic pathway.

치아재식술을 통한 치주 조직 재생의 가능성 문헌고찰

박도영 ( Do Young Park ),김병옥 ( Byung Ock Kim ),유상준 ( Sang Joun Yu ) 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.2

Periodontitis is caused primarily by dental plaque microorganism. Periodontitis is characterized by the destruction of the periodontium. Sometimes for the patients with severe periodontal diseases who have advanced bone destruction, both surgical and non-surgical methods may not be successful. In these cases, intentional replantation may be an alternative choice at least for a period of time. The following applications are needed for successful periodontal regeneration of replanted teeth. First of all, mechanical, environmental, inflammatory trauma need to be minimized to protect the periodontal tissue on the root surface and alveolar bone surface in the extraction socket. Second, root surface treatment is needed to remove infected tissue and conserve as much cementum as possible. Third, growth factors can be applied to promote the regeneration of periodontal tissue. Fourth, various cell-based approaches can be applied for periodontal tissue regeneration in severe compromised periodontal defect.

A case report of nonsurgical treatment of maxillary anterior peri-implantitis

Min-Cheol Yang,Seok-Hwan Jeong,Kyu-Man Lee,김병옥 조선대학교 치의학연구원 2022 Oral Biology Research (Oral Biol Res) Vol.46 No.4

Peri-implantitis is defined as an inflammatory reaction associated with bone loss beyond the initial biologic bone remodeling around a functional implant. This study aims to report the clinical and radiographic outcomes of nonsurgical peri-implantitis treatment in the maxillary anterior area. Subgingival irrigation with normal saline and antiseptics, systemic antibiotics, laser decontamination, and biofilm decontamination approach in department of periodontics and water irrigation as home care were conducted. Nonsurgical treatment of peri-implantitis resulted in healing, such as improvements in bleeding tendency, pus discharge, bad odor, and gingival recession, and resulted in a little bit bone changes around implants with severe bone resorption and shallow pocket probing depth over a 5-yr maintenance period. We confirmed that nonsurgical therapy with regular follow-up maintained peri-implantitis with an initial shallow pocket probing depth in the maxillary anterior area.

The etiology and possible molecular mechanisms underlying calcium channel blocker-induced gingival enlargement: a narrative review

Seul Lee,유형근 조선대학교 치의학연구원 2022 Oral Biology Research (Oral Biol Res) Vol.46 No.4

Gingival enlargement, defined as the abnormal proliferation of gingival tissue, can be caused by exposure to poor oral hygiene, periodontal diseases, or systemic drugs such as antihypertensive, immunosuppressive, and anticonvulsant agents. Although numerous clinical studies have examined drug-induced gingival enlargement, there is limited evidence on the molecular mechanisms underlying this disease. Therefore, the current study aims to summarize the available literature on the effects of systemic drugs such as antihypertensive agents and calcium channel blockers used for the treatment of cardiac diseases on gingival enlargement expression, and to discuss possible molecular mechanisms underlying drug-induced gingival enlargement.