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자기영동을 이용한 자성입자 분리 마이크로 칩 제작 및 성능평가
고정상,Go, Jeung-Sang 대한기계학회 2007 大韓機械學會論文集B Vol.31 No.4
We developed a microfluidic platform able to control the trap and release of magnetic beads used for separation of a specific biomolecules. The magnetic beads can be trapped and released conditionally by controlling the difference between the Stokes force induced by the fluid flow and magnetic force resulting from a permanent magnet. The permanent magnet of CoNiP alloy is electroplated. It is characterized to have the 1369 Oe of coercivity, 1762 Gauss of remanence, and 0.603MGOe of (BH)max. Through the experimental and numerical investigation, the magnetic beads are trapped under the flow velocity of 17 ${\mu}m/s$ and are released perfectly above the velocity of 174 ${\mu}m/s$.
오픈소스 기반의 하수 시설물 데이터베이스의 효율적 구축
고정상,徐春旭,윤희천,Ko, Jeongsang,Xu, Chunxu,Yun, Heecheon 한국측량학회 2022 한국측량학회지 Vol.40 No.5
Effective data management of underground facilities is very important in terms of human life. For this, input of up-to-date and high-accuracy data should be preceded. Therefore, it is important to have an efficient data input method. In this study, by developing a sewage facility site survey program using open source software, paper drawings could be replaced with tablet PCs. By using a tablet PC, figures and property information acquired from the field are transmitted in real time through a database server. PostGIS query is developed to automate structured editing to minimize manual work in constructing a GIS (Geographic Information System) database for sewage facilities. did. In addition, the database was built using the sewage facility GIS database building program. As a result of comparing and analyzing the existing sewage facility database construction, work process, and work time, the work process was simplified and work time was shortened. In addition, through simple customization of open source software, it will be able to be used for field surveys and database construction in other fields.
고정상,장승철,박덕수,김형훈,Yeon Kyoung Bahk 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.12
This study introduces a new concept for a simple, efficient and cheap sensitivity amplification of a Quartz Crystal Microbalance (QCM) based immunosensor system for the detection of tumor necrosis factor-alpha (TNF-α, TNF) by using an in-built magnetic system. The frequency shift due to the applied magnetic field was successfully observed on magnetic particles labeled detection antibodies, anti-human TNF-α, which were bound to the immunologically captured TNF-α on the gold coated quartz crystals. In the present system, the magnitude of frequency shift depends on both the strength of magnetic field and the amount of target antigen applied. Significant signal amplification was observed when the additional built-in residual stress generated by the modified magnetic particles under the magnetic field applied. Used in conjunction with a sandwich type non-competitive immunoassay format, the lower detection limit was calculated to be 25 ngmL−1 and showed good linearity up to TNF-α concentrations as high as 2.0 μgmL−1. The sensitivity, most importantly, was improved up to 4.3 times compared with the same QCM system which was used only an antigen-antibody binding without additional magnetic amplification.
스냅스루 좌굴을 이용한 미소스위치의 설계, 제작 및 실험
고정상,조영호,곽병만,박관흠,Go, Jeung-Sang,Cho, Young-Ho,Kwak, Byung-Man,Park, Kwan-Hum 대한기계학회 1996 大韓機械學會論文集A Vol.20 No.2
A snapping-beam microswitch has been designed, fabricated and tested. From a design analysis, necessary and sufficient conditions for a snap-through switching fouction have been derived for a clamped shallow beam. The necessary condition has resulted in a geometric relation, in which the ratio of beam thickness to initial beam deflection plays a key role in the snapping ability. The sufficient condition for the snapping action has been obtained as a function of the inertia force due to applied acceleration, and the electrostatic force, adjustable by an inter-electrode voltage. For experimental investigations, a set of microbeams of silicon dioxide/$P^+$silicon bimorphs have been fabricated. Geometric size and mechanical behavior of each material film have been measured from on-chip test structures. Estimated and measured characteristics of the fabricated devices are compared.