C형 간염바이러스 항체 면역블롯검사에서 불확정판정을 받은 헌혈자의 HCV 양성 확인

조연정,서동희,황병갑,김동집,정남현 大韓輸血學會 2001 大韓輸血學會誌 Vol.12 No.2

도시지역 보건사업에서 컴퓨터의 활용방안에 관한 연구

염용태,이명숙,조병희,송동빈 고려대학교 의과대학 1990 고려대 의대 잡지 Vol.27 No.2

Nacessity of new communication media in information society is repidly increasing in many fields of Korea. It includes the field of primary helath care in the courses of collecting informations on demographic feature, social characteristics and health behavior of peoples. In light of above reasons, the authors attempted to utilize personal computers for the primary health services to promote health of unban people as a pilot study in Guro-6- Dong, Seoul. Five nurses working in Guro-6-Dong Health Subcenter completed family health records of 3,930 households among the total of 4,270. A total of 3,904 family health records among 3,930 were computerized and sorted out in categories of population characteristics, population dymanics, characteristics of householders, housing, family planning, maternal and child health(M.C.H), health status of residents and of others. Names of risky category in M.C.H, and family planning were listed and the lists were handed to the nurses concerned in order to practice proper cares in time. Sorted data were compared with ones of City of Seoul, average of other cities, and ones of nationwide. With the results of above practice, in terms of utilization of computer in uban primary health sevices, the following strategy was proposed. In order to provide proper health services the unban people demanded, efficient devices of information collection, processing and interpretation systems on health were urgently needed in every dong unit(health subcenter) of health centers. Recommended was personal computer network as a new communication media. Additional advantages of the devices were continuity and efficiency in services, and utilization in evaluation of health services and analysis of cost -effectiveness.

조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

原料乳의 貯藏中 滴定酸度 및 總生菌數의 變化에 關한 硏究 : Ⅰ. 貯藏時間 및 溫度差에 의한 變化 Ⅰ. Studies on the Time of Storage and Difference Temperature

趙永來,尹東根,李乙熙 진주산업대학교 1980 論文集 Vol.18 No.-

機械搾乳한 原料乳를 5℃,15℃ 및 30℃에서 保存하여 5時間 간격을 두고 經視的으로 酸度測定, 總生菌數檢査 및 大腸菌群檢査를 한 結果는 다음과 같다. 1. 搾乳卽時의 滴定酸度는 0.1455%였다. 2. 搾乳卽時의 總生菌數는 4.5×10exp(4)/㎖이었다. 3. 滴定酸度는 5℃에서는 25時間이상 20℃에서는 5∼10時間 사이에 30℃에서는 5時間에서 기준치 이하였다. 4. 총생균수는 5℃에서는 20시간 이상 20℃에서는 10시간 30℃에서는 5시간 保存까지 基準(2×10exp(6)/㎖)이하로 나타났다. 5. 搾乳卽時 大腸菌群은 4.0×10exp(2)/㎖이었으나 15時間까지는 增加하였고 그 率은 점차 감소되었다. This study was conducted to fine out the titratable acidity and microbiological change during storage raw maik. It were taken from the mixed milk by Holstein cows in Jinju Agriculture & Forestry Junier Technical College under temperature of 30℃, 20℃ and 5℃ each for 25 hours in the laboratory. The results obtained were as follows; 1. The titratable acidity was 0.1455% in right after the milking. 2. The total bacterial counts of right after the milking was 4.5×10exp(4)/㎖. 3. The titratable acidity did not increase up to the inedible level of goverment standard until more than 25, between 5 and 10. and before 5 hours at 5, 20 and 30℃ conditions, respectively. 4. The total bacterial counts of raw milk did not increase up to inedible level of goverment standard until more than 20, 10 and 5 hours at 5, 20, and 30℃ conditions, respectively. 5. The colforms count of raw milk of right after the milking was 4.0×10exp(2)㎖ and there after it were incressed a space of 15 hours. But as the time passed it were decreased every temperature conditions.

한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

시분할 방식 고주파 공진 인버터의 특성해석

조규판,원재선,김동희,노채균,배영호 영남대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.28 No.1

In this paper, we propose the high frequency resonant inverter of the time sharing type which has the effects that the duty cycle of each elements and the thermal loss can be reduce. The analysis of the proposed circuit is described generally by using the normalized parameters. Also, the principle of basic operation and the characteristics of drive were estimated by the switching frequency and the load parameters. And we got the data for designing by the characteristic values obtained at the estimate of characteristic. At the same time, the example of the design's method was proposed and the waveforms of simulation were compared with theoretical waveforms. It is certain that the proposed circuit will be used and expanded in the high frequency power supplies like induction heating systems.

동물과 사람유래 Vancomycin 내성 장구균의 항균제 감수성 비교

조윤상,이희수,김종만,류판동,박용호,유한상,이문한 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.1

It has been recently reported the possibility in the bansfer of antimicrobial resistance to other animals and humans. In particular, vancomycin resistant enterococci (VRE), which have been known as a principal antimicrobial resistant bacteria in humans, have been increased as a pathogen of nosocomial infections. And then animal VRE were suspected as an origin of human VRE. In this study, we isolated Enterococcus spp. from animals, identified by bio- chemical tests, examined for antimicrobial susceptibility, and then compared the antimicrobial susceptibility of VRE among each other as well as human VRE. Enterococcus iecium (29%) was predominant in Enterococcus species (n=122) isolated from animal feces in this study. E. hirae, E. iecalis, E. casseliflam and E. gallinarum were also isolated as rates of 24%, 21%, 16% and 7%, respectively. The resistance of enterococci to penicillin and tetracycline were 66% and 78%, respectively, and the susceptibility of them to chloramphenicol was 66%. Antimicrobial susceptibility test has shown that 91% of VRE from humans (n=11) was susceptible to chloramphenicol and all resistant to penicillin, rifampin and streptomycin. Seventy-five percentage of VRE from chickens (n = 12) was susceptible to rifampin and resistances of them to penicillin, tetracycline and sbeptomycin were 75%, 83%, and l00%, respectively. Therefore, we confirmed the difference of antimicrobial susceptibility from animals and humans, and the antimicrobial susceptibility test could be one of the simple and useful methods for the epidemiological survey of VRE.

Phase-Shift를 이용한 시분할형 부하병렬 고주파 인버터의 특성해석에 관한 연구

조규판,원재선,김동희,노채균,원규식,심광열 영남대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.28 No.2

A half bridge time sharing type load parallel high frequency resonant inverter to give VVVF function in the inverter used as power source of induction heating at high frequency is presented in this paper. This proposed inverter can reduce distribution of the switching current because of using the current of serial resonant circuit to the input current of the parallel one and this paper also realize the output control of independence irrespective of the switching frequency using Phase-Shift. The analysis of the proposed circuit is generally described by using the normalized parameters. Also, the principle of basic operation and the its characteristics are estimated by the parameters, such as switching frequency, the variation of phase angle(φ) of Phase-Shift. It is certain that the proposed circuit will be used and expanded in the high frequency power supplies like induction heating systems.

적층고무 받침을 사용한 강상형교의 시공단계별 대기온도변화에 따른 Steel Box의 실제 온도에 관한 연구

조동영,유희중,임삼규 호남대학교 2003 호남대학교 학술논문집 Vol.24 No.2

Random Amplified Polymorphic DNA Typing에 의한 동물과 사람 유래 Vancomycin 내성 장구균의 유전학적 비교

조윤상,이희수,김종만,류판동,박용호,유한상,이문한 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.1

It has been recently reported the possibility in the transfer of antimicrobial resistant to other animals and humans. In particular, the occurrence of vancomycin resistant enterococci (VRE), which have been known as a principal antimicrobial resistant bacteria in humans, has been increased as a pathogen of nosocomial infections. And then animal VRE were suspected as an origin of human VRE. In this work, we investigated the relatedness between VRE from animals and humans through random amplified polymorphic DNA (RAPD) typing. The genetic relatedness of vanA, vanB, vanC-1 and vanC-2 genotypes was examined by RAPD typing, respectively. van4 genotypes have not been shown high genetic relationship each other, containing VRE from humans (n = 8) and chickens (n = 5). In vanB genotypes from humans (n = 3), 2 isolates were made up one cluster, shown 77.8% homology. Chicken isolates of vanC-1 genotypes (n = 11) were constituted 2 clusters and the homology of 2 clusters was 81.8% and 80.0%, respectively. In case of vanC-2 genotypes (n = 19), 2 isolates from pigs have been shown 76.9% homology. But, between VRE from animals and humans, the isolates of high genetic relationship could not be found and RAPD typing was a useful epidemiological method that could be confirmed the genetic relationship among VRE.