노인의 자살사고에 영향을 미치는 신체적, 정신적, 사회적 위험 요인

최미지,김동현,이강욱,이중서 대한신경정신의학회 2015 신경정신의학 Vol.54 No.4

Objectives The aim of this study is to examine the physical, psychological, and social factors influencing suicidal ideation among elderly Koreans. Methods Community Health Survey data obtained in 2013 were used for this study with a sample of 4367 elderly who reside in Gangwon province. The data were analyzed using the chi-square test and the logistic regression test to examine the relationship between suicidal ideation and other variables. Results Depression was the single most influential variable, both directly and indirectly increas¬ing suicidal ideation. In particular, the increase of suicidal ideation among those with severe dis¬ease was affected by depression. Perceived poor social support and perceived poor health sta¬tus were the two highest risk factors after depression, implying that subjective assessment of the elderly affects suicidal ideation significantly. Poor economic status and current smoking showed significantly higher risk for women only, although poor health, poor social support, and poor so¬cial activity commonly attributed to the risk of suicidal ideation in both genders. Conclusion This study suggests that suicidal ideation among the elderly should be approached in a multi-perspective way considering depression, social support, and physical health. It is notable that not only lack of resources but also perceived sense of poor social and physical well-being significantly affect suicidal ideation.

성인애착이 이성관계 만족도에 미치는 영향에서 정서조절곤란의 매개효과

최미지,김현숙 한국재활심리학회 2019 재활심리연구 Vol.26 No.3

본 연구는 대학생의 성인애착과 이성관계 만족도, 정서조절곤란의 관계를 알아보고, 대학생의 성인애착과 이성관계 만족도의 관계에서 정서조절곤란의 매개효과를 알아보고자 하였다. 연구를 위하여 B시에 위치한 4년제 대학교 대학생들을 대상으로 실시한 자기보고식 설문지 205부를 사용하여 상관분석과 중다회귀분석을 실시하였다. 연구결과로는 첫째, 성인애착의 두 차원의 애착불안과 애착회피는 이성관계 만족도와 부적상관을, 정서조절곤란과 이성관계 만족도 또한 부적상관을, 애착불안과 애착회피는 정서조절곤란과 정적상관이 있는 것으로 나타났다. 둘째, 애착불안과 이성관계 만족도와의 관계에서 정서조절곤란의 매개효과는 통계적으로 유의미하지 않는 것으로 나타났다. 셋째, 애착회피와 이성관계 만족도와의 관계에서 정서조절곤란의 매개효과는 부분 매개하는 것으로 나타났다. 즉, 대학생의 회피애착이 이성관계 만족도에 직접적인 영향을 미칠 뿐만 아니라 정서조절곤란을 통하여 이성관계 만족도에 간접적인 영향을 주는 것으로 나타났다. 본 연구의 결과는 불안정한 애착을 형성한 개인이 자신의 정서를 인식하고 이해하여 표현함에 있어 어려움을 갖는다는 사실에 기초하여 이성관계에서 어려움을 호소하는 대학생의 성인애착과 감정을 인식하고 표현하는 정서조절에 대한 개입이 필요하다는 시사점을 제공하였다는 데에 의의가 있다.

한국판 문제행동 평가도구(Behavior Problems Inventory-01) 표준화 연구

최미지(Miji Choi),김예니(Yeni Kim),반지정(Ji-Jeong Ban),황석현(Samuel Suk-Hyun Hwang),김붕년(Bung-Nyun Kim),양영희(Young-Hui Yang) 대한소아청소년정신의학회 2017 소아청소년정신의학 Vol.28 No.4

Objectives: The purpose of this study was to examine the reliability and validity of the Korean version of the Behavior Problems Inventory (BPI-01) among children and adolescents aged between 3 and 18. Methods: The control group consisting of one hundred children and adolescents was recruited from schools and the patient group consisting of forty one children and adolescents with autism spectrum disorder were recruited from a hospital. We compared the measurements of both groups. To assess the concurrent validity of the BPI-01, we compared the problem behavior index of the Korean Scale of Independent Behavior-Revised (K-SIB-R) and, to assess the discriminant validity, we compared the Korean version of the Child Behavior Checklist (K-CBCL). The Cronbach’s alpha of the BPI-01 was measured to assess its reliability. Correlation analyses between the BPI-01 and the other scale were carried out to examine the former’s concurrent and discriminant validity. Results: The patient group showed a significantly higher score for all three subscales of the BPI than the control group. The Cronbach’s alpha was 0.92 for the total severity score of the BPI and ranged between 0.67–0.89 for each subscale in the patient group. All subscales of the BPI-01’s, i.e., self injurious behavior, stereotyped behavior and aggressive/destructive behavior, were significantly correlated with the corresponding subscales of the K-SIB-R. The BPI-01 generally did not demonstrate any significant correlation with emotional items such as anxiety/depression in the K-CBCL. Especially, the BPI-01’s stereotyped behavior subscale showed little correlation with externalizing behaviors such as social problems and aggressive behaviors. Conclusion: This study found that the Korean version of BPI-01 is a reliable and valid behavior rating instrument for problem behavior in developmental disabilities among children and adolescents.

ANK₃ 유전자 다형성과 조현병의 연관성에 대한 연합연구

양소영,허익수,조은영,최미지,박태성,이유상,홍경수,Yang, So Yung,Huh, Ik-Soo,Cho, Eun Young,Choi, Mi Ji,Park, Taesung,Lee, Yu-Sang,Hong, Kyung Sue 대한생물정신의학회 2015 생물정신의학 Vol.22 No.4

Objectives Previous genome-wide association studies have indicated the association between ankyrin 3 (ANK3) and the vulnerability of schizophrenia. We investigated the association between single nucleotide polymorphisms (SNPs) covering the whole ANK3 locus and schizophrenia in the Korean population. Methods The study subjects were 582 patients with schizophrenia and 502 healthy controls. Thirty-eight tag SNPs on ANK3 and five additional SNPs showing significant association with schizophrenia in previous studies were genotyped. Results Three (rs10994181, rs16914791, rs1938526) of 43 SNPs showed a nominally significant association (p < 0.05) with at least one genotype model. But none of these associations remained significant after adjusting for multiple testing errors with Bonferroni's correction. Conclusions We could not identify a significant association between ANK3 and schizophrenia in the Korean population. However, three SNPs showing an association signal with nominal significance need to be investigated in future studies with higher statistical power and more specific phenotype crossing the current diagnostic categories.

양극성 장애 환자에서 비정형 항정신병약물 치료 후에 나타나는 지연성 운동장애와 지연성 근긴장이상의 유병률 및 위험요인

이아람,김주현,백지현,김지선,최미지,윤세창,하규섭,홍경수,Lee, Ahram,Kim, Joo Hyun,Baek, Ji Hyun,Kim, Ji Sun,Choi, Mi Ji,Yoon, Se Chang,Ha, Kyooseob,Hong, Kyung Sue 대한생물정신의학회 2015 생물정신의학 Vol.22 No.4

Objectives Second-generation antipsychotics (SGAs) are frequently used in the treatment of bipolar disorder. However, there is still no consensus on their risk of tardive movement syndromes especially for first-generation antipsychotics (FGAs)-naive patients. This study aimed to investigate the prevalence and associated factors of SGAs-related tardive dyskinesia and tardive dystonia in patients with bipolar disorder, in a naturalistic out-patient clinical setting. Methods The authors assessed 78 non-elderly patients with bipolar (n = 71) or schizoaffective disorder (n = 7) who received SGAs with a combined use of mood stabilizers for more than three months without previous exposure to FGAs. Multiple direct assessments were performed and hospital records longer than one recent year describing any observed tardive movement symptoms were also reviewed. Results The prevalence rates of tardive dyskinesia and tardive dystonia were 7.7% and 6.4%, respectively. These patients were being treated with ziprasidone, risperidone, olanzapine, quetiapine, or paliperidone at the time of the onset of the movement symptoms. Tardive dyskinesia was mostly observed in the orolingual area, and tardive dystonia was most frequently detected in oromandibular area. A past history of acute dystonia was significantly associated with presence of both tardive movement syndromes. Conclusions Our findings suggest that SGAs-related tardive movement syndromes occur in a substantial portion of bipolar disorder patients. Acute dystonia, a reported risk factor of tardive movement syndromes in the era of FGAs is confirmed as a risk factor of both tardive dyskinesia and tardive dystonia that were induced-by SGAs.